Biochemical Journal

2-APB-potentiated channels amplify CatSper-induced Ca signals in human sperm

Lefièvre, L., Nash, K., Mansell, S., Costello, S., Punt, E., Correia, J., Morris, J., Kirkman-Brown, J., Wilson, S. M., Barratt, C. L. R. & Publicover, S. Dec-2012 In : Biochemical Journal. 448, 2, p. 189-200, 12 p.

Research output: Contribution to journal › Article

Akt is efficiently activated by PIF-pocket- and PtdIns(3,4,5)P-3-dependent mechanisms leading to resistance to PDK1 inhibitors

Najafov, A., Shpiro, N. & Alessi, D. R. Dec-2012 In : Biochemical Journal. 448, 2, p. 285-295, 11 p.

Research output: Contribution to journal › Article

AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

Bultot, L., Guigas, B., Von Wilamowitz-Moellendorff, A., Maisin, L., Vertommen, D., Hussain, N., Beullens, M., Guinovart, J. J., Foretz, M., Viollet, B., Sakamoto, K., Hue, L. & Rider, M. H. 1-Apr-2012 In : Biochemical Journal. 443, p. 193-203, 11 p.

Research output: Contribution to journal › Article

The anti-neurodegenerative agent clioquinol regulates the transcription factor FOXO1a

Cameron, A. R., Wallace, K., Logie, L., Prescott, A. R., Unterman, T. G., Harthill, J. & Rena, G. 1-Apr-2012 In : Biochemical Journal. 443, p. 57-64, 8 p.

Research output: Contribution to journal › Article

Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells

Navarro, M. N., Sinclair, L. V., Feijoo-Carnero, C., Clarke, R., Matthews, S. A. & Cantrell, D. A. 15-Mar-2012 In : Biochemical Journal. 442, 3, p. 649-659, 11 p.

Research output: Contribution to journal › Article

Both p110 alpha and p110 beta isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor

Berenjeno, I. M., Guillermet-Guibert, J., Pearce, W., Gray, A., Fleming, S. & Vanhaesebroeck, B. 15-Feb-2012 In : Biochemical Journal. 442, p. 151-159, 9 p.

Research output: Contribution to journal › Article

Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes

Hjerpe, R., Thomas, Y., Chen, J., Zemla, A., Curran, S., Shpiro, N., Dick, L. R. & Kurz, T. 1-Feb-2012 In : Biochemical Journal. 441, p. 927-936, 10 p.

Research output: Contribution to journal › Article

Characterization of the cellular action of the MSK inhibitor SB-747651A

Naqvi, S., Macdonald, A., McCoy, C. E., Darragh, J., Reith, A. D. & Arthur, J. S. C. 1-Jan-2012 In : Biochemical Journal. 441, p. 347-357, 11 p.

Research output: Contribution to journal › Article

Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system

Goh, E. T. H., Arthur, J. S. C., Cheung, P. C. F., Akira, S., Toth, R. & Cohen, P. 1-Jan-2012 In : Biochemical Journal. 441, p. 339-346, 8 p.

Research output: Contribution to journal › Article

Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice

Meakin, P. J., Harper, A. J., Hamilton, D. L., Gallagher, J., McNeilly, A. D., Burgess, L. A., Vaanholt, L. M., Bannon, K. A., Latcham, J., Hussain, I., Speakman, J. R., Howlett, D. R. & Ashford, M. L. J. 1-Jan-2012 In : Biochemical Journal. 441, p. 285-296, 12 p.

Research output: Contribution to journal › Article