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  1. Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1

    Najafov, A., Sommer, E. M., Axten, J. M., DeYoung, M. P. & Alessi, D. R. 15 Jan 2011 In : Biochemical Journal. 433, p. 357-369 13 p.

    Research output: Contribution to journalArticle

  2. Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis

    Dias, M. V. B., Snee, W. C., Bromfield, K. M., Payne, R. J., Palaninathan, S. K., Ciulli, A., Howard, N. I., Abell, C., Sacchettini, J. C. & Blundell, T. L. 2011 In : Biochemical Journal. 436, 3, p. 729-739 11 p.

    Research output: Contribution to journalArticle

  3. TTBK2 kinase substrate specificity and the impact of spinocerebellar-ataxia-causing mutations on expression, activity, localization and development

    Bouskila, M., Esoof, N., Gay, L., Fang, E. H., Deak, M., Begley, M. J., Cantley, L. C., Prescott, A., Storey, K. G. & Alessi, D. R. 2011 In : Biochemical Journal. 437, p. 157-167 11 p.

    Research output: Contribution to journalArticle

  4. Human OGA binds substrates in a conserved peptide recognition groove

    Schimpl, M., Schuettelkopf, A. W., Borodkin, V. S. & van Aalten, D. M. F. 15 Nov 2010 In : Biochemical Journal. 432, p. 1-7 7 p.

    Research output: Contribution to journalArticle

  5. Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells

    Matthews, S. A., Navarro, M. N., Sinclair, L. V., Emslie, E., Feijoo-Carnero, C. & Cantrell, D. A. 15 Nov 2010 In : Biochemical Journal. 432, p. 153-163 11 p.

    Research output: Contribution to journalArticle

  6. Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)

    Pearce, L. R., Alton, G. R., Richter, D. T., Kath, J. C., Lingardo, L., Chapman, J., Hwang, C. & Alessi, D. R. 15 Oct 2010 In : Biochemical Journal. 431, p. 245-255 11 p.

    Research output: Contribution to journalArticle

  7. 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization

    Nichols, R. J., Dzamko, N., Morrice, N. A., Campbell, D. G., Deak, M., Ordureau, A., Macartney, T., Tong, Y., Shen, J., Prescott, A. R. & Alessi, D. R. 15 Sep 2010 In : Biochemical Journal. 430, p. 393-404 12 p.

    Research output: Contribution to journalArticle

  8. Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser(910)/Ser(935), disruption of 14-3-3 binding and altered cytoplasmic localization

    Dzamko, N., Deak, M., Hentati, F., Reith, A. D., Prescott, A. R., Alessi, D. R. & Nichols, R. J. 15 Sep 2010 In : Biochemical Journal. 430, p. 405-413 9 p.

    Research output: Contribution to journalArticle

  9. Loss of AMP-activated protein kinase alpha 2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia

    Beall, C., Piipari, K., Al-Qassab, H., Smith, M. A., Parker, N., Carling, D., Viollet, B., Withers, D. J. & Ashford, M. L. J. 15 Jul 2010 In : Biochemical Journal. 429, 2, p. 323-333 11 p.

    Research output: Contribution to journalArticle

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