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  1. Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)

    Pearce, L. R., Alton, G. R., Richter, D. T., Kath, J. C., Lingardo, L., Chapman, J., Hwang, C. & Alessi, D. R. 15 Oct 2010 In : Biochemical Journal. 431, p. 245-255 11 p.

    Research output: Contribution to journalArticle

  2. 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization

    Nichols, R. J., Dzamko, N., Morrice, N. A., Campbell, D. G., Deak, M., Ordureau, A., Macartney, T., Tong, Y., Shen, J., Prescott, A. R. & Alessi, D. R. 15 Sep 2010 In : Biochemical Journal. 430, p. 393-404 12 p.

    Research output: Contribution to journalArticle

  3. Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser(910)/Ser(935), disruption of 14-3-3 binding and altered cytoplasmic localization

    Dzamko, N., Deak, M., Hentati, F., Reith, A. D., Prescott, A. R., Alessi, D. R. & Nichols, R. J. 15 Sep 2010 In : Biochemical Journal. 430, p. 405-413 9 p.

    Research output: Contribution to journalArticle

  4. Loss of AMP-activated protein kinase alpha 2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia

    Beall, C., Piipari, K., Al-Qassab, H., Smith, M. A., Parker, N., Carling, D., Viollet, B., Withers, D. J. & Ashford, M. L. J. 15 Jul 2010 In : Biochemical Journal. 429, 2, p. 323-333 11 p.

    Research output: Contribution to journalArticle

  5. Structural basis for the efficient phosphorylation of AZT-MP (3 '-azido-3 '-deoxythymidine monophosphate) and dGMP by Plasmodium falciparum type I thymidylate kinase

    Whittingham, J. L., Carrero-Lerida, J., Brannigan, J. A., Ruiz-Perez, L. M., Silva, A. P. G., Fogg, M. J., Wilkinson, A. J., Gilbert, I. H., Wilson, K. S. & Gonzalez-Pacanowska, D. 15 Jun 2010 In : Biochemical Journal. 428, p. 499-509 11 p.

    Research output: Contribution to journalArticle

  6. Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins

    Remenyi, J., Hunter, C. J., Cole, C., Ando, H., Impey, S., Monk, C. E., Martin, K. J., Barton, G. J., Hutvagner, G. & Arthur, J. S. C. 1 Jun 2010 In : Biochemical Journal. 428, 2, p. 281-291 11 p.

    Research output: Contribution to journalArticle

  7. Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK

    Li, X., Vadrevu, S., Dunlop, A., Day, J., Advant, N., Troeger, J., Klussmann, E., Jaffray, E., Hay, R. T., Adams, D. R., Houslay, M. D. & Baillie, G. S. 15 May 2010 In : Biochemical Journal. 428, p. 55-65 11 p.

    Research output: Contribution to journalArticle

  8. Bioinformatic and experimental survey of 14-3-3-binding sites

    Johnson, C., Crowther, S., Stafford, M. J., Campbell, D. G., Toth, R. & MacKintosh, C. 1 Apr 2010 In : Biochemical Journal. 427, 1, p. 69-78 10 p.

    Research output: Contribution to journalArticle

  9. Molecular mechanism of elongation factor 1A inhibition by a Legionella pneumophila glycosyltransferase

    Hurtado-Guerrero, R., Zusman, T., Pathak, S., Ibrahim, A. F. M., Shepherd, S., Prescott, A., Segal, G. & van Aalten, D. M. F. 15 Mar 2010 In : Biochemical Journal. 426, p. 281-292 12 p.

    Research output: Contribution to journalArticle

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