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  1. Transcriptionally correlated subcellular dynamics of MBNL1 during lens development and their implication for the molecular pathology of myotonic dystrophy type 1

    Coleman, S. M., Prescott, A. R. & Sleeman, J. E. Mar 2014 In : Biochemical Journal. 458, 2, p. 267-280 14 p.

    Research output: Contribution to journalArticle

  2. Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity

    Houde, V. P., Ritorto, M. S., Gourlay, R., Davies, P., Shpiro, N., Sakamoto, K. & Alessi, D. R. 15 Feb 2014 In : Biochemical Journal. 458, 1, p. 41-56 16 p.

    Research output: Contribution to journalArticle

  3. Bisubstrate UDP-peptide conjugates as human O-GlcNAc transferase inhibitors

    Borodkin, V. S., Schimpl, M., Gundogdu, M., Rafie, K., Dorfmueller, H. C., Robinson, D. A. & van Aalten, D. M. F. 1 Feb 2014 In : Biochemical Journal. 457, 3, p. 497-502 6 p.

    Research output: Contribution to journalArticle

  4. RAM function is dependent on Kapβ2-mediated nuclear entry

    Gonatopoulos-Pournatzis, T. & Cowling, V. H. 1 Feb 2014 In : Biochemical Journal. 457, 3, p. 473-484 12 p.

    Research output: Contribution to journalArticle

  5. Cap-binding complex (CBC)

    Gonatopoulos-Pournatzis, T. & Cowling, V. H. 15 Jan 2014 In : Biochemical Journal. 457, 2, p. 231-242 12 p.

    Research output: Contribution to journalScientific review

  6. Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases

    Banerjee, S., Buhrlage, S. J., Huang, H-T., Deng, X., Zhou, W., Wang, J., Traynor, R., Prescott, A. R., Alessi, D. R. & Gray, N. S. 1 Jan 2014 In : Biochemical Journal. 457, 1, p. 215-225 11 p.

    Research output: Contribution to journalArticle

  7. Nrf2 affects the efficiency of mitochondrial fatty acid oxidation

    Ludtmann, M. H. R., Angelova, P. R., Zhang, Y., Abramov, A. Y. & Dinkova-Kostova, A. T. 2014 In : Biochemical Journal. 457, 3, p. 415-424 10 p.

    Research output: Contribution to journalArticle

  8. Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Serine65

    Kazlauskaite, A., Kondapalli, C., Gourlay, R., Campbell, D. G., Ritorto, M. S., Hofmann, K., Alessi, D. R., Knebel, A., Trost, M. & Muqit, M. M. K. 2014 In : Biochemical Journal.

    Research output: Contribution to journalArticle

  9. Chemical tools to probe cellular O-GlcNAc signalling

    Ostrowski, A. & van Aalten, D. M. F. 15 Nov 2013 In : Biochemical Journal. 456, 1, p. 1-12 12 p.

    Research output: Contribution to journalArticle

  10. Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites

    Aregger, M. & Cowling, V. H. 18 Jul 2013 In : Biochemical Journal. 455, 1, p. 67-73 7 p.

    Research output: Contribution to journalArticle

  11. Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies

    Davies, P., Hinkle, K. M., Sukar, N. N., Sepulveda, B., Mesias, R., Serrano, G., Alessi, D. R., Beach, T. G., Benson, D. L., White, C. L., Cowell, R. M., Das, S. S., West, A. B. & Melrose, H. L. 1 Jul 2013 In : Biochemical Journal. 453, 1, p. 101-113 13 p.

    Research output: Contribution to journalArticle

  12. Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors

    Sommer, E. M., Dry, H., Cross, D., Guichard, S., Davies, B. R. & Alessi, D. R. 15 Jun 2013 In : Biochemical Journal. 452, 3, p. 499-508 10 p.

    Research output: Contribution to journalArticle

  13. Characterisation of a pre-export enzyme-chaperone complex on the twin-arginine transport pathway

    Dow, J. M., Gabel, F., Sargent, F. & Palmer, T. 15 May 2013 In : Biochemical Journal. 452, 1, p. 57-66 10 p.

    Research output: Contribution to journalArticle

  14. The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system

    Strickson, S., Campbell, D. G., Emmerich, C. H., Knebel, A., Plater, L., Ritorto, M. S., Shpiro, N. & Cohen, P. 1 May 2013 In : Biochemical Journal. 451, 3, p. 427-437 11 p.

    Research output: Contribution to journalArticle

  15. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability

    Bett, J. S., Ibrahim, A. F. M., Garg, A. K., Kelly, V., Pedrioli, P., Rocha, S. & Hay, R. T. 15 Apr 2013 In : Biochemical Journal. 451, 2, p. 185-194 10 p.BJ20130026

    Research output: Contribution to journalArticle

  16. The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction

    Ohta, A., Schumacher, F-R., Mehellou, Y., Johnson, C., Knebel, A., Macartney, T. J., Wood, N. T., Alessi, D. R. & Kurz, T. 1 Apr 2013 In : Biochemical Journal. 451, 1, p. 111-122 12 p.

    Research output: Contribution to journalArticle

  17. DNA-binding regulates site-specific ubiquitination of IRF-1

    Landré, V., Pion, E., Narayan, V., Xirodimas, D. P. & Ball, K. L. 1 Feb 2013 In : Biochemical Journal. 449, 3, p. 707-717 11 p.

    Research output: Contribution to journalArticle

  18. AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues.

    Chen, H-Y., Ducommun, S., Quan, C., Xie, B., Li, M., Wasserman, D. H., Sakamoto, K., MacKintosh, C. & Chen, S. 15 Jan 2013 In : Biochemical Journal. 449, 2, p. 479-489 11 p.

    Research output: Contribution to journalArticle

  19. Characterization of Staphylococcus aureus EssB, an integral membrane component of the Type VII secretion system: atomic resolution crystal structure of the cytoplasmic segment

    Zoltner, M., Fyfe, P. K., Palmer, T. & Hunter, W. N. 15 Jan 2013 In : Biochemical Journal. 449, 2, p. 469-477 9 p.

    Research output: Contribution to journalArticle

  20. CFTR mutations altering CFTR fragmentation

    Tosoni, K., Stobbart, M., Cassidy, D. M., Venerando, A., Pagano, M. A., Luz, S., Amaral, M. D., Kunzelmann, K., Pinna, L. A., Farinha, C. M. & Mehta, A. 2013 In : Biochemical Journal. 449, 1, p. 295-305 11 p.

    Research output: Contribution to journalArticle

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