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Biochemical Journal

  1. Mechanism of activation of SGK3 by growth factors-via the Class 1 and Class 3 PI3Ks

    Malik, N., Macartney, T., Hornberger, A., Anderson, K., Tovell, H., Prescott, A. R. & Alessi, D. R. 17 Nov 2017 In : Biochemical Journal.

    Research output: Contribution to journalArticle

  2. Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson’s disease kinase

    Lis, P., Burel, S., Steger, M., Mann, M., Brown, F., Diez, F., Tonelli, F., Holton, J. L., Winglok Ho, P., Ho, S-L., Chou, M-Y., Polinski, N. K., Martinez, T. N., Davies, P. & Alessi, D. R. 10 Nov 2017 In : Biochemical Journal.

    Research output: Contribution to journalArticle

  3. Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils

    Fan, Y., Howden, A. J. M., Sarhan, A. R., Lis, P., Ito, G., Martinez, T. N., Brockmann, K., Gasser, T., Alessi, D. R. & Sammler, E. 10 Nov 2017 In : Biochemical Journal.

    Research output: Contribution to journalArticle

  4. The dual-function chaperone HycH improves assembly of the formate hydrogenlyase complex

    Lindenstrauß, U., Skorupa, P., McDowall, J. S., Sargent, F. & Pinske, C. Sep 2017 In : Biochemical Journal. 474, 17, p. 2937-2350 14 p.

    Research output: Contribution to journalArticle

  5. Interleukin-1 and TRAF6-dependent activation of TAK1 in the absence of TAB2 and TAB3

    Zhang, J., Macartney, T., Peggie, M. & Cohen, P. 26 Jul 2017 In : Biochemical Journal. 474, 13, p. 2235-2248 16 p.

    Research output: Contribution to journalArticle

  6. The mechanism of activation of IRAK1 and IRAK4 by interleukin-1 and TollLike receptor agonists

    Vollmer, S., Strickson, S., Zhang, T., Gray, N., Lee, K., Rao, V. & Cohen, P. 6 Jun 2017 In : Biochemical Journal. 474, 12, p. 2027-2038 12 p.

    Research output: Contribution to journalArticle

  7. Structural Basis of Molecular Recognition of Helical Histone H3 Tail by PHD Finger Domains

    Bortoluzzi, A., Amato, A., Lucas, X., Blank, M. & Ciulli, A. 4 May 2017 In : Biochemical Journal. 474, 10, p. 1633-1651 19 p.

    Research output: Contribution to journalArticle

  8. Ubiquitin and Parkinson's disease through the looking glass of Genetics

    Walden, H. & Muqit, M. M. K. May 2017 In : Biochemical Journal. 474, 9, p. 1439-1451 13 p.

    Research output: Contribution to journalReview article

  9. The biochemical properties of the two Arabidopsis thaliana isochorismate synthases

    Macaulay, K. M., Heath, G. A., Ciulli, A., Murphy, A. M., Abell, C., Carr, J. P. & Smith, A. G. 28 Apr 2017 In : Biochemical Journal. 474, 10, p. 1579-1590 12 p.

    Research output: Contribution to journalArticle

  10. Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β

    Bakshi, S., Taylor, J., Strickson, S., Macartney, T. & Cohen, P. 15 Mar 2017 In : Biochemical Journal. 474, 7, p. 1163-1174 12 p.

    Research output: Contribution to journalArticle

  11. GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis

    Zibrova, D., Vandermoere, F., Göransson, O., Peggie, M., Mariño, K., Knierim, A., Spengler, K., Weigert, C., Viollet, B., Morrice, N. A., Sakamoto, K. & Heller, R. 7 Mar 2017 In : Biochemical Journal. 474, 6, p. 983-1001 19 p.

    Research output: Contribution to journalArticle

  12. Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages

    Darling, N. J., Toth, R., Arthur, J. S. C. & Clark, K. 3 Feb 2017 In : Biochemical Journal. 474, 4, p. 521-537 17 p.

    Research output: Contribution to journalArticle

  13. c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production

    Dunn, S., Lombardi, O. & Cowling, V. 20 Jan 2017 In : Biochemical Journal. 474, 3, p. 377-384 8 p.

    Research output: Contribution to journalArticle

  14. Mechanism and disease-association of E2 conjugating enzymes: lessons from UBE2T and UBE2L3

    Alpi, A. F., Chaugule, V. & Walden, H. 11 Oct 2016 In : Biochemical Journal. 473, 20, p. 3401-3419 19 p.

    Research output: Contribution to journalReview article

  15. Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors

    Ito, G., Katsemonova, K., Tonelli, F., Lis, P., Baptista, M., Shpiro, N., Duddy, G., Wilson, S., Wing-Lok Ho, P., Ho, S-L., Reith, A. D. & Alessi, D. 30 Aug 2016 In : Biochemical Journal. 473, 17, p. 2671-2685 15 p.

    Research output: Contribution to journalArticle

  16. EssC: domain structures inform on the elusive translocation channels in the Type VII secretion system.

    Zoltner, M., Ng, W. M. A. V., Money, J. J., Fyfe, P. K., Kneuper, H., Palmer, T. & Hunter, W. N. Jul 2016 In : Biochemical Journal. 473, 13, p. 1941-1952 12 p.

    Research output: Contribution to journalArticle

  17. Nucleocytoplasmic human O-GlcNAc transferase is sufficient for O-GlcNAcylation of mitochondrial proteins

    Trapannone, R., Mariappa, D., Ferenbach, A. T. & van Aalten, D. M. F. 10 Jun 2016 In : Biochemical Journal. 473, 12, p. 1693-1702 10 p.

    Research output: Contribution to journalArticle

  18. Chemical Ubiquitination for Decrypting a Cellular Code

    Stanley, M. & Virdee, S. 11 May 2016 In : Biochemical Journal. 473, 10, p. 1297-1314 18 p.

    Research output: Contribution to journalReview article

  19. Biophysical characterization of laforin-carbohydrate interaction

    Dias, D. M., Furtado, J., Wasielewski, E., Cruz, R., Costello, B., Cole, L., Faria, T. Q., Baaske, P., Brito, R. M. M., Ciulli, A., Simões, I., Macedo-Ribeiro, S., Faro, C., Geraldes, C. F. G. C. & Castanheira, P. 1 Feb 2016 In : Biochemical Journal. 473, 3, p. 335-345 11 p.

    Research output: Contribution to journalArticle

  20. Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms

    Ross, F. A., Jensen, T. E. & Hardie, D. G. 15 Jan 2016 In : Biochemical Journal. 473, 2, p. 189-199 11 p.

    Research output: Contribution to journalArticle

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