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  1. Dissecting fragment-based lead discovery at the von hippel-lindau protein: Hypoxia inducible factor 1α protein-protein interface

    Van Molle, I., Thomann, A., Buckley, D. L., So, E. C., Lang, S., Crews, C. M. & Ciulli, A. 26 Oct 2012 In : Chemistry & Biology. 19, 10, p. 1300-1312 13 p.

    Research output: Contribution to journalArticle

  2. ALDH2 mediates 5-nitrofuran activity in multiple species

    Zhou, L., Ishizaki, H., Spitzer, M., Taylor, K. L., Temperley, N. D., Johnson, S. L., Brear, P., Gautier, P., Zeng, Z., Mitchell, A., Narayan, V., McNeil, E. M., Melton, D. W., Smith, T. K., Tyers, M., Westwood, N. J. & Patton, E. E. 27 Jul 2012 In : Chemistry & Biology. 19, 7, p. 883-892 10 p.

    Research output: Contribution to journalArticle

  3. Synergy of peptide and sugar in O-GlcNAcase substrate recognition

    Schimpl, M., Borodkin, V. S., Gray, L. J. & van Aalten, D. M. F. 24 Feb 2012 In : Chemistry & Biology. 19, 2, p. 173-178 6 p.

    Research output: Contribution to journalArticle

  4. Discovery of potent and selective covalent inhibitors of JNK

    Zhang, T., Inesta-Vaquera, F., Niepel, M., Zhang, J., Ficarro, S. B., Machleidt, T., Xie, T., Marto, J. A., Kim, N., Sim, T., Laughlin, J. D., Park, H., LoGrasso, P. V., Patricelli, M., Nomanbhoy, T. K., Sorger, P. K., Alessi, D. R. & Gray, N. S. 27 Jan 2012 In : Chemistry & Biology. 19, 1, p. 140-154 15 p.

    Research output: Contribution to journalArticle

  5. A designed inhibitor of a clc antiporter blocks function through a unique binding mode

    Howery, A. E., Elvington, S., Abraham, S. J., Choi, K-H., Dworschak-Simpson, S., Phillips, S., Ryan, C. M., Sanford, R. L., Almqvist, J., Tran, K., Chew, T. A., Zachariae, U., Andersen, O. S., Whitelegge, J., Matulef, K., Du Bois, J. & Maduke, M. C. 2012 In : Chemistry & Biology. 19, 11, p. 1460-1470 11 p.

    Research output: Contribution to journalArticle

  6. HSF1-Dependent Upregulation of Hsp70 by Sulfhydryl-Reactive Inducers of the KEAP1/NRF2/ARE Pathway

    Zhang, Y., Ahn, Y-H., Benjamin, I. J., Honda, T., Hicks, R. J., Calabrese, V., Cole, P. A. & Dinkova-Kostova, A. T. 23 Nov 2011 In : Chemistry & Biology. 18, 11, p. 1355-1361 7 p.

    Research output: Contribution to journalArticle

  7. Analyzing airway inflammation with chemical biology: dissection of acidic mammalian chitinase function with a selective drug-like inhibitor

    Sutherland, T. E., Andersen, O. A., Betou, M., Eggleston, I. M., Maizels, R. M., van Aalten, D. & Allen, J. E. 27 May 2011 In : Chemistry & Biology. 18, 5, p. 569-579 11 p.

    Research output: Contribution to journalArticle

  8. Novel Ligands for a Purine Riboswitch Discovered by RNA-Ligand Docking

    Daldrop, P., Reyes, F. E., Robinson, D. A., Hammond, C. M., Lilley, D. M., Batey, R. T. & Brenk, R. 25 Mar 2011 In : Chemistry & Biology. 18, 3, p. 324-335 12 p.

    Research output: Contribution to journalArticle

  9. Natural product-guided discovery of a fungal chitinase inhibitor

    Rush, C. L., Schuettelkopf, A. W., Hurtado-Guerrero, R., Blair, D. E., Ibrahim, A. F. M., Desvergnes, S., Eggleston, I. M. & van Aalten, D. M. F. 22 Dec 2010 In : Chemistry & Biology. 17, 12, p. 1275-1281 7 p.

    Research output: Contribution to journalArticle

  10. Cell-penetrant, nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases

    Dorfmueller, H. C., Borodkin, V. S., Schimpl, M., Zheng, X., Kime, R., Read, K. D. & van Aalten, D. M. F. 24 Nov 2010 In : Chemistry & Biology. 17, 11, p. 1250-1255 6 p.

    Research output: Contribution to journalArticle

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