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ChemMedChem

  1. 3-(2-oxoethylidene)indolin-2-one derivatives activate Nrf2 and inhibit NF-κB: potential candidates for chemoprevention

    Nagle, A. A., Reddy, S. A., Bertrand, H., Tajima, H., Dang, T-M., Wong, S-C., Hayes, J. D., Wells, G. & Chew, E-H. 2014 In : ChemMedChem. 9, 8, p. 1763-1774 12 p.

    Research output: Contribution to journalArticle

  2. Cellular accumulation, lipophilicity and photocytotoxicity of diazido platinum(IV) anticancer complexes

    Pizarro, A. M., Mcquitty, R. J., Mackay, F. S., Zhao, Y., Woods, J. A. & Sadler, P. J. 2014 In : ChemMedChem. 9, 6, p. 1169-1175 7 p.

    Research output: Contribution to journalArticle

  3. From on-target to off-target activity: identification and optimisation of Trypanosoma brucei GSK3 inhibitors and their characterisation as anti-Trypanosoma brucei drug discovery lead molecules

    Woodland, A., Grimaldi, R., Luksch, T., Cleghorn, L. A. T., Ojo, K. K., Van Voorhis, W. C., Brenk, R., Frearson, J. A., Gilbert, I. H. & Wyatt, P. G. Jul 2013 In : ChemMedChem. 8, 7, p. 1127-1137 11 p.

    Research output: Contribution to journalArticle

  4. Structure-Activity Relationship Studies of Pyrrolone Antimalarial Agents

    Murugesan, D., Kaiser, M., White, K. L., Norval, S., Riley, J., Wyatt, P. G., Charman, S. A., Read, K. D., Yeates, C. & Gilbert, I. H. 2013 In : ChemMedChem.

    Research output: Contribution to journalArticle

  5. Design, Synthesis and Biological Evaluation of Trypanosoma brucei Trypanothione Synthetase Inhibitors

    Spinks, D., Torrie, L. S., Thompson, S., Harrison, J. R., Frearson, J. A., Read, K. D., Fairlamb, A. H., Wyatt, P. G. & Gilbert, I. H. 2 Jan 2012 In : ChemMedChem. 7, 1, p. 95-106 12 p.

    Research output: Contribution to journalArticle

  6. Identification of Inhibitors of the Leishmania cdc2-Related Protein Kinase CRK3

    Cleghorn, L. A. T., Woodland, A., Collie, I. T., Torrie, L. S., Norcross, N., Luksch, T., Mpamhanga, C., Walker, R. G., Mottram, J. C., Brenk, R., Frearson, J. A., Gilbert, I. H. & Wyatt, P. G. 9 Dec 2011 In : ChemMedChem. 6, 12, p. 2214-2224 11 p.

    Research output: Contribution to journalArticle

  7. Design, Synthesis, and Evaluation of 5 '-Diphenyl Nucleoside Analogues as Inhibitors of the Plasmodium falciparum dUTPase

    Hampton, S. E., Baragana, B., Schipani, A., Bosch-Navarrete, C., Alexander Musso-Buendia, J., Recio, E., Kaiser, M., Whittingham, J. L., Roberts, S. M., Shevtsov, M., Brannigan, J. A., Kahnberg, P., Brun, R., Wilson, K. S., Gonzalez-Pacanowska, D., Johansson, N. G. & Gilbert, I. H. 4 Oct 2011 In : ChemMedChem. 6, 10, p. 1816-1831 16 p.

    Research output: Contribution to journalArticle

  8. Optimisation of the Anti-Trypanosoma brucei Activity of the Opioid Agonist U50488

    Smith, V. C., Cleghorn, L. A. T., Woodland, A., Spinks, D., Hallyburton, I., Collie, I. T., Mok, N. Y., Norval, S., Brenk, R., Fairlamb, A. H., Frearson, J. A., Read, K. D., Gilbert, I. H. & Wyatt, P. G. 4 Oct 2011 In : ChemMedChem. 6, 10, p. 1832-1840 9 p.

    Research output: Contribution to journalArticle

  9. Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1

    Spinks, D., Ong, H. B., Mpamhanga, C. P., Shanks, E. J., Robinson, D. A., Collie, I. T., Read, K. D., Frearson, J. A., Wyatt, P. G., Brenk, R., Fairlamb, A. H. & Gilbert, I. H. 7 Feb 2011 In : ChemMedChem. 6, 2, p. 302-308 7 p.

    Research output: Contribution to journalArticle

  10. Synthesis and Evaluation of Indatraline-Based Inhibitors for Trypanothione Reductase

    Walton, J. G. A., Jones, D. C., Kiuru, P., Durie, A. J., Westwood, N. J. & Fairlamb, A. H. 7 Feb 2011 In : ChemMedChem. 6, 2, p. 321-328 8 p.

    Research output: Contribution to journalArticle

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