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Diabetes

  1. The Na+/glucose co-transporter inhibitor canagliflozin activates AMP-activated protein kinase by inhibiting mitochondrial function and increasing cellular AMP levels

    Hawley, S., Ford, R. J., Smith, B. K., Gowans, G. J., Mancini, S. J., Pitt, R. D., A. Day, E., Salt, I. P., Steinberg, G. R. & Hardie, D. G. 3 Jun 2016 In : Diabetes.

    Research output: Contribution to journalArticle

  2. Integrin-linked kinase in muscle is necessary for the development of insulin resistance in diet-induced obese mice

    Kang, L., Mokshagundam, S., Reuter, B., Lark, D. S., Sneddon, C. C., Hennayake, C., Williams, A. S., Bracy, D. P., James, F. D., Pozzi, A., Zent, R. & Wasserman, D. H. 1 Jun 2016 In : Diabetes. 65, 6, p. 1590-1600 11 p.

    Research output: Contribution to journalArticle

  3. Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension and heart disease

    Yaghootkar, H. , Lotta, L. A. , Tyrrell, J. , Smit, R. A. J. , Jones, S. E. , Donnelly, L. , Beaumont, R. , Campbell, A. , Tuke, M. A. , Hayward, C. , Ruth, K. S. , Padmanabhan, S. , Jukema, J. W. , Palmer, C. C. , Hattersley, A. , Freathy, R. M. , Langenberg, C. , Wareham, N. J. , Wood, A. R. & 6 others Murray, A., Weedon, M. N., Sattar, N., Pearson, E., Scott, R. A. & Frayling, T. M. 26 Apr 2016 In : Diabetes.

    Research output: Contribution to journalArticle

  4. Dissecting the etiology of type 2 diabetes in the Pima Indian population

    Pearson, E. R. Dec 2015 In : Diabetes. 64, 12, p. 3993-3995 3 p.

    Research output: Contribution to journalComment/debate

  5. Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion

    Morris, A. D. & 26 others Yaghootkar, H., Stancáková, A., Freathy, R. M., Vangipurapu, J., Weedon, M. N., Xie, W., Wood, A. R., Ferrannini, E., Mari, A., Ring, S. M., Lawlor, D. A., Davey Smith, G., Jørgensen, T., Hansen, T., Pedersen, O., Steinthorsdottir, V., Guðbjartsson, D. F., Thorleifsson, G., Thorsteinsdottir, U., Stefansson, K., Hattersley, A. T., Walker, M., McCarthy, M. I., Palmer, C. N. A., Laakso, M. & Frayling, T. M. Jun 2015 In : Diabetes. 64, 6, p. 2279-2285 7 p.

    Research output: Contribution to journalArticle

  6. Diazoxide improves hormonal counterregulatory responses to acute hypoglycemia in long-standing Type 1 Diabetes

    George, P. S., Tavendale, R., Palmer, C. N. A. & McCrimmon, R. J. Jun 2015 In : Diabetes. 64, 6, p. 2234-2241 8 p.

    Research output: Contribution to journalArticle

  7. Association of organic cation transporter 1 with intolerance to metformin in Type 2 diabetes: a GoDARTS study

    Dujic, T., Zhou, K., Donnelly, L. A., Tavendale, R., Palmer, C. N. A. & Pearson, E. R. May 2015 In : Diabetes. 64, 5, p. 1786-1793 8 p.

    Research output: Contribution to journalArticle

  8. Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation

    Pirkmajer, S., Kulkarni, S. S., Tom, R. Z., Ross, F. A., Hawley, S. A., Hardie, D. G., Zierath, J. R. & Chibalin, A. V. Feb 2015 In : Diabetes. 64, 2, p. 360-369 10 p.

    Research output: Contribution to journalArticle

  9. Heterozygous SOD2 deletion impairs glucose-stimulated insulin secretion, but not insulin action in high fat-fed mice

    Kang, L., Dai, C., Lustig, M. E., Bonner, J. S., Mayes, W. H., Mokshagundam, S., James, F. D., Thompson, C. S., Lin, C-T., Perry, C. G. R., Anderson, E. J., Neufer, P. D., Wasserman, D. H. & Powers, A. C. Nov 2014 In : Diabetes. 63, 11, p. 3699-3710 12 p.

    Research output: Contribution to journalArticle

  10. Glucose-6-phosphate-mediated activation of liver glycogen synthase plays a key role in hepatic glycogen synthesis

    von Wilamowitz-Moellendorff, A., Hunter, R. W., García-Rocha, M., Kang, L., López-Soldado, I., Lantier, L., Patel, K., Peggie, M. W., Martínez-Pons, C., Voss, M., Calbó, J., Cohen, P. T. W., Wasserman, D. H., Guinovart, J. J. & Sakamoto, K. Dec 2013 In : Diabetes. 62, 12, p. 4070-4082 13 p.

    Research output: Contribution to journalArticle

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