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Diabetes

  1. An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

    Scott, R. A. , Scott, L. J. , Maegi, R. , Marullo, L. , Gaulton, K. J. , Kaakinen, M. , Pervjakova, N. , Pers, T. H. , Johnson, A. D. , Eicher, J. D. , Jackson, A. U. , Ferreira, T. , Lee, Y. , Ma, C. , Steinthorsdottir, V. , Thorleifsson, G. , Qi, L. , Van Zuydam, N. R. , Mahajan, A. , Chen, H. & 156 others Almgren, P., Voight, B. F., Grallert, H., Mueller-Nurasyid, M., Ried, J. S., Rayner, N. W., Robertson, N., Karssen, L. C., Van Leeuwen, E. M., Willems, S. M., Fuchsberger, C., Kwan, P., Teslovich, T. M., Chanda, P., Li, M., Lu, Y., Dina, C., Thuillier, D., Yengo, L., Jiang, L., Sparso, T., Kestler, H. A., Chheda, H., Eisele, L., Gustafsson, S., Franberg, M., Strawbridge, R. J., Benediktsson, R., Hreidarsson, A. B., Kong, A., Sigurdsson, G., Kerrison, N. D., Luan, J., Liang, L., Meitinger, T., Roden, M., Thorand, B., Esko, T., Mihailov, E., Fox, C., Liu, C-T., Rybin, D., Isomaa, B., Lyssenko, V., Tuomi, T., Couper, D. J., Pankow, J. S., Grarup, N., Have, C. T., Jorgensen, M. E., Jorgensen, T., Linneberg, A., Cornelis, M. C., Van Dam, R. M., Hunter, D. J., Kraft, P., Sun, Q., Edkins, S., Owen, K. R., Perry, J. R. B., Wood, A. R., Zeggini, E., Tajes-Fernandes, J., Abecasis, G. R., Bonnycastle, L. L., Chines, P. S., Stringham, H. M., Koistinen, H. A., Kinnunen, L., Sennblad, B., Muehleisen, T. W., Noethen, M. M., Pechlivanis, S., Baldassarre, D., Gertow, K., Humphries, S. E., Tremoli, E., Klopp, N., Meyer, J., Steinbach, G., Wennauer, R., Eriksson, J. G., Mannisto, S., Peltonen, L., Tikkanen, E., Charpentier, G., Eury, E., Lobbens, S., Gigante, B., Leander, K., McLeod, O., Bottinger, E. P., Gottesman, O., Ruderfer, D., Blueher, M., Kovacs, P., Tonjes, A., Maruthur, N. M., Scapoli, C., Erbel, R., Joeckel, K-H., Moebus, S., De Faire, U., Hamsten, A., Stumvoll, M., Deloukas, P., Donnelly, P. J., Frayling, T. M., Hattersley, A. T., Ripatti, S., Salomaa, V., Pedersen, N. L., Boehm, B. O., Bergman, R. N., Collins, F. S., Mohlke, K. L., Tuomilehto, J., Hansen, T., Pedersen, O., Barroso, I., Lannfelt, L., Ingelsson, E., Lind, L., Lindgren, C. M., Cauchi, S., Froguel, P., Loos, R. J. F., Balkau, B., Boeing, H., Franks, P. W., Gurrea, A. B., Palli, D., Van der Schouw, Y. T., Altshuler, D., Groop, L. C., Langenberg, C., Wareham, N. J., Sijbrands, E., Van Duijn, C. M., Florez, J. C., Meigs, J. B., Boerwinkle, E., Gieger, C., Strauch, K., Metspalu, A., Morris, A. D., Palmer, C. N. A., Hu, F. B., Thorsteinsdottir, U., Stefansson, K., Dupuis, J., Morris, A. P., Boehnke, M., McCarthy, M. I., Prokopenko, I. & for the DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium Nov 2017 In : Diabetes. 66, 11, p. 2888-2902 15 p.

    Research output: Contribution to journalArticle

  2. A Genome-Wide Association Study of IVGTT-Based Measures of First Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

    Wood, A. R. , Jonsson, A. , Jackson, A. U. , Wang, N. , van Leewen, N. , Palmer, N. D. , Kobes, S. , Deelen, J. , Boquete-Vilarino, L. , Paananen, J. , Stančáková, A. , Boomsma, D. I. , de Geus, E. J. C. , Eekhoff, E. M. W. , Fritsche, A. , Kramer, M. H. H. , Nijpels, G. , Simonis-Bik, A. M. C. , van Haeften, T. W. , Mahajan, A. & 31 others Boehnke, M., Bergman, R. N., Tuomilehto, J., Collins, F. S., Mohlke, K. L., Banasik, K., Groves, C. J., McCarthy, M. I., Pearson, E. R., Natali, A., Mari, A., Buchanan, T. A., Taylor, K. D., Xiang, A. H., Gjesing, A. P., Grarup, N., Eiberg, H., Pedersen, O., Chen, Y-D., Laakso, M., Norris, J. M., Smith, U., Wagenknecht, L. E., Baier, L., Bowden, D. W., Hansen, T., Walker, M., Watanabe, R. M., 't Hart, L. M., Hanson, R. L. & Frayling, T. M. 21 Jul 2017 In : Diabetes. 66, 8, p. 2296-2309 14 p.

    Research output: Contribution to journalArticle

  3. A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

    Manning, A. , Highland, H. M. , Gasser, J. , Sim, X. , Tukiainen, T. , Fontanillas, P. , Grarup, N. , Rivas, M. A. , Mahajan, A. , Locke, A. E. , Cingolani, P. , Pers, T. H. , Viñuela, A. , Brown, A. A. , Wu, Y. , Flannick, J. , Fuchsberger, C. , Gamazon, E. R. , Gaulton, K. J. , Im, H. K. & 242 others Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., DePristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., Hrabé de Angelis, M., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Fowler, S. P., Arya, R., DeFronzo, R. A., Abboud, H. E., Syvänen, A-C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S-T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J-Y., Han, B-G., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., Melander, O., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., Liu, J., Khor, C-C., Chia, K. S., Lim, W. Y., Cheng, C-Y., Chan, E., Tai, E. S., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Kravic, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Owen, K. R., Farmer, A. J., Frayling, T. M., O'Rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stančáková, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Kesaniemi, Y. A., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M. Jul 2017 In : Diabetes. 66, 7, p. 2019-2032 14 p.

    Research output: Contribution to journalArticle

  4. High intensity exercise as a dishabituating stimulus restores counterregulatory responses in recurrently hypoglycemic rodents

    McNeilly, A. D., Gallagher, J. R., Huang, J. T-J., Ashford, M. L. J. & McCrimmon, R. J. 1 Jun 2017 In : Diabetes. 66, 6, p. 1696-1702 7 p.

    Research output: Contribution to journalArticle

  5. Nrf2-mediated neuroprotection response to recurrent hypoglycemia is insufficient to prevent cognitive impairment in a rodent model of type 1 diabetes

    McNeilly, A. D., Gallagher, J. R., Dinkova-Kostova, A. T., Hayes, J. D., Sharkey, J., Ashford, M. L. J. & McCrimmon, R. J. 1 Oct 2016 In : Diabetes. 65, 10, p. 3151-3160 10 p.

    Research output: Contribution to journalArticle

  6. The common p.R114W HNF4A mutation causes a distinct clinical subtype of monogenic diabetes

    Laver, T. W., Colclough, K., Shepherd, M., Patel, K., Houghton, J. A. L., Dusatkova, P., Pruhova, S., Morris, A. D., Palmer, C. N., McCarthy, M. I., Ellard, S., Hattersley, A. T. & Weedon, M. N. Oct 2016 In : Diabetes. 65, 10, p. 3212-3217 6 p.

    Research output: Contribution to journalArticle

  7. The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

    Hawley, S., Ford, R. J., Smith, B. K., Gowans, G. J., Mancini, S. J., Pitt, R. D., A. Day, E., Salt, I. P., Steinberg, G. R. & Hardie, D. G. Sep 2016 In : Diabetes. 65, 9, p. 2784-2794 11 p.

    Research output: Contribution to journalArticle

  8. Genetic evidence for a link between favorable adiposity and lower risk of type 2 diabetes, hypertension and heart disease

    Yaghootkar, H. , Lotta, L. A. , Tyrrell, J. , Smit, R. A. J. , Jones, S. E. , Donnelly, L. , Beaumont, R. , Campbell, A. , Tuke, M. A. , Hayward, C. , Ruth, K. S. , Padmanabhan, S. , Jukema, J. W. , Palmer, C. C. , Hattersley, A. , Freathy, R. M. , Langenberg, C. , Wareham, N. J. , Wood, A. R. , Murray, A. & 5 others Weedon, M. N., Sattar, N., Pearson, E., Scott, R. A. & Frayling, T. M. Aug 2016 In : Diabetes. 65, 8, p. 2448-2460 13 p.

    Research output: Contribution to journalArticle

  9. Integrin-linked kinase in muscle is necessary for the development of insulin resistance in diet-induced obese mice

    Kang, L., Mokshagundam, S., Reuter, B., Lark, D. S., Sneddon, C. C., Hennayake, C., Williams, A. S., Bracy, D. P., James, F. D., Pozzi, A., Zent, R. & Wasserman, D. H. 1 Jun 2016 In : Diabetes. 65, 6, p. 1590-1600 11 p.

    Research output: Contribution to journalArticle

  10. Dissecting the etiology of type 2 diabetes in the Pima Indian population

    Pearson, E. R. Dec 2015 In : Diabetes. 64, 12, p. 3993-3995 3 p.

    Research output: Contribution to journalComment/debate

  11. Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion

    Yaghootkar, H. , Stancáková, A. , Freathy, R. M. , Vangipurapu, J. , Weedon, M. N. , Xie, W. , Wood, A. R. , Ferrannini, E. , Mari, A. , Ring, S. M. , Lawlor, D. A. , Davey Smith, G. , Jørgensen, T. , Hansen, T. , Pedersen, O. , Steinthorsdottir, V. , Guðbjartsson, D. F. , Thorleifsson, G. , Thorsteinsdottir, U. , Stefansson, K. & 7 others Hattersley, A. T., Walker, M., Morris, A. D., McCarthy, M. I., Palmer, C. N. A., Laakso, M. & Frayling, T. M. Jun 2015 In : Diabetes. 64, 6, p. 2279-2285 7 p.

    Research output: Contribution to journalArticle

  12. Diazoxide improves hormonal counterregulatory responses to acute hypoglycemia in long-standing Type 1 Diabetes

    George, P. S., Tavendale, R., Palmer, C. N. A. & McCrimmon, R. J. Jun 2015 In : Diabetes. 64, 6, p. 2234-2241 8 p.

    Research output: Contribution to journalArticle

  13. Association of organic cation transporter 1 with intolerance to metformin in Type 2 diabetes: a GoDARTS study

    Dujic, T., Zhou, K., Donnelly, L. A., Tavendale, R., Palmer, C. N. A. & Pearson, E. R. May 2015 In : Diabetes. 64, 5, p. 1786-1793 8 p.

    Research output: Contribution to journalArticle

  14. Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation

    Pirkmajer, S., Kulkarni, S. S., Tom, R. Z., Ross, F. A., Hawley, S. A., Hardie, D. G., Zierath, J. R. & Chibalin, A. V. Feb 2015 In : Diabetes. 64, 2, p. 360-369 10 p.

    Research output: Contribution to journalArticle

  15. Heterozygous SOD2 deletion impairs glucose-stimulated insulin secretion, but not insulin action in high fat-fed mice

    Kang, L., Dai, C., Lustig, M. E., Bonner, J. S., Mayes, W. H., Mokshagundam, S., James, F. D., Thompson, C. S., Lin, C-T., Perry, C. G. R., Anderson, E. J., Neufer, P. D., Wasserman, D. H. & Powers, A. C. Nov 2014 In : Diabetes. 63, 11, p. 3699-3710 12 p.

    Research output: Contribution to journalArticle

  16. Glucose-6-phosphate-mediated activation of liver glycogen synthase plays a key role in hepatic glycogen synthesis

    von Wilamowitz-Moellendorff, A., Hunter, R. W., García-Rocha, M., Kang, L., López-Soldado, I., Lantier, L., Patel, K., Peggie, M. W., Martínez-Pons, C., Voss, M., Calbó, J., Cohen, P. T. W., Wasserman, D. H., Guinovart, J. J. & Sakamoto, K. Dec 2013 In : Diabetes. 62, 12, p. 4070-4082 13 p.

    Research output: Contribution to journalArticle

  17. Mendelian randomisation studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes

    Yaghootkar, H. , Lamina, C. , Scott, R. A. , Dastani, Z. , Hivert, M-F. , Warren, L. L. , Stancáková, A. , Buxbaum, S. G. , Lyytikäinen, L-P. , Henneman, P. , Wu, Y. , Cheung, C. Y. Y. , Pankow, J. S. , Jackson, A. U. , Gustafsson, S. , Zhao, J. H. , Ballantyne, C. M. , Xie, W. , Bergman, R. N. , Boehnke, M. & 58 others el Bouazzaoui, F., Collins, F. S., Dunn, S. H., Dupuis, J., Forouhi, N. G., Gillson, C., Hattersley, A. T., Hong, J., Kähönen, M., Kuusisto, J., Kedenko, L., Kronenberg, F., Doria, A., Assimes, T. L., Ferrannini, E., Hansen, T., Hao, K., Häring, H., Knowles, J. W., Lindgren, C. M., Nolan, J. J., Paananen, J., Pedersen, O., Quertermous, T., Smith, U., the GENESIS consortium, the RISC consortium, Lehtimäki, T., Liu, C-T., Loos, R. J. F., McCarthy, M. I., Morris, A. D., Vasan, R. S., Spector, T. D., Teslovich, T. M., Tuomilehto, J., Willems van Dijk, K., Viikari, J. S., Zhu, N., Langenberg, C., Ingelsson, E., Semple, R. K., Sinaiko, A. R., Palmer, C. N. A., Walker, M., Lam, K. S. L., Paulweber, B., Mohlke, K. L., van Duijn, C., Raitakari, O. T., Bidulescu, A., Wareham, N. J., Laakso, M., Waterworth, D. M., Lawlor, D. A., Meigs, J. B., Richards, J. B. & Frayling, T. M. Oct 2013 In : Diabetes. 62, 10, p. 3589-3598 10 p.

    Research output: Contribution to journalArticle

  18. Mitochondrial Substrate Availability and its Role in Lipid-Induced Insulin Resistance and Proinflammatory Signalling in Skeletal Muscle

    Lipina, C., Macrae, K., Suhm, T., Weigert, C., Blachnio-Zabielska, A., Baranowksi, M., Gorski, J., Burgess, K. & Hundal, H. S. Oct 2013 In : Diabetes. 62, 10, p. 3426-3436 11 p.

    Research output: Contribution to journalArticle

  19. AMPK: a target for drugs and natural products with effects on both diabetes and cancer

    Hardie, D. G. Jul 2013 In : Diabetes. 62, 7, p. 2164-2172 9 p.

    Research output: Contribution to journalArticle

  20. Biomarkers for type 2 diabetes and impaired fasting glucose using a non-targeted metabolomics approach

    Menni, C. , Fauman, E. , Erte, I. , Perry, J. R. B. , Kastenmüller, G. , Shin, S-Y. , Petersen, A-K. , Hyde, C. , Psatha, M. , Ward, K. J. , Yuan, W. , Milburn, M. , Palmer, C. N. A. , Frayling, T. M. , Trimmer, J. , Bell, J. T. , Gieger, C. , Mohney, R. , Brosnan, M. J. , Suhre, K. & 2 others Soranzo, N. & Spector, T. D. 2013 In : Diabetes.

    Research output: Contribution to journalArticle

  21. The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway

    't Hart, L. M. , Fritsche, A. , Nijpels, G. , van Leeuwen, N. , Donnelly, L. A. , Dekker, J. M. , Alssema, M. , Fadista, J. , Carlotti, F. , Gjesing, A. P. , Palmer, C. N. A. , van Haeften, T. W. , Herzberg-Schäfer, S. A. , Simonis-Bik, A. M. C. , Houwing-Duistermaat, J. J. , Helmer, Q. , Deelen, J. , Guigas, B. , Hansen, T. , Machicao, F. & 14 others Willemsen, G., Heine, R. J., Kramer, M. H. H., Holst, J. J., de Koning, E. J. P., Häring, H-U., Pedersen, O., Groop, L., de Geus, E. J. C., Slagboom, P. E., Boomsma, D. I., Eekhoff, E. M. W., Pearson, E. R. & Diamant, M. 2013 In : Diabetes.

    Research output: Contribution to journalArticle

  22. Cellular Responses to the Metal-Binding Properties of Metformin

    Logie, L., Harthill, J., Patel, K., Bacon, S., Hamilton, D. L., Macrae, K., McDougall, G., Wang, H-H., Xue, L., Jiang, H., Sakamoto, K., Prescott, A. R. & Rena, G. Jun 2012 In : Diabetes. 61, 6, p. 1423-1433 11 p.

    Research output: Contribution to journalArticle

  23. Deep Resequencing Unveils Genetic Architecture of ADIPOQ and Identifies a Novel Low-Frequency Variant Strongly Associated With Adiponectin Variation

    Warren, L. L. , Li, L. , Nelson, M. R. , Ehm, M. G. , Shen, J. , Fraser, D. J. , Aponte, J. L. , Nangle, K. L. , Slater, A. J. , Woollard, P. M. , Hall, M. D. , Topp, S. D. , Yuan, X. , Cardon, L. R. , Chissoe, S. L. , Mooser, V. , Morris, A. D. , Palmer, C. N. A. , Perry, J. R. , Frayling, T. M. & 2 others Whittaker, J. C. & Waterworth, D. M. May 2012 In : Diabetes. 61, 5, p. 1297-1301 5 p.

    Research output: Contribution to journalArticle

  24. Total soluble and endogenous secretory receptor for advanced glycation end products as predictive biomarkers of coronary heart disease risk in patients with type 2 Diabetes: an analysis from the CARDS trial

    Colhoun, H. M., Betteridge, D. J., Durrington, P., Hitman, G., Neil, A., Livingstone, S., Charlton-Menys, V., Bao, W., DeMicco, D. A., Preston, G. M., Deshmukh, H., Tan, K. & Fuller, J. H. Sep 2011 In : Diabetes. 60, 9, p. 2379-2385 7 p.

    Research output: Contribution to journalArticle

  25. Deletion of Lkb1 in Pro-Opiomelanocortin Neurons Impairs Peripheral Glucose Homeostasis in Mice

    Claret, M. , Smith, M. A. , Knauf, C. , Al-Qassab, H. , Woods, A. , Heslegrave, A. , Piipari, K. , Emmanuel, J. J. , Colom, A. , Valet, P. , Cani, P. D. , Begum, G. , White, A. , Mucket, P. , Peters, M. , Mizuno, K. , Batterham, R. L. , Giese, K. P. , Ashworth, A. , Burcelin, R. & 3 others Ashford, M. L., Carling, D. & Withers, D. J. Mar 2011 In : Diabetes. 60, 3, p. 735-745 11 p.

    Research output: Contribution to journalArticle

  26. Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance.

    De Silva, N. M. G. , Freathy, R. M. , Palmer, T. M. , Donnelly, L. A. , Luan, J. , Gaunt, T. , Langenberg, C. , Weedon, M. N. , Shields, B. , Knight, B. A. , Ward, K. J. , Sandhu, M. S. , Harbord, R. M. , McCarthy, M. I. , Smith, G. D. , Ebrahim, S. , Hattersley, A. T. , Wareham, N. , Lawlor, D. A. , Morris, A. D. & 2 others Palmer, C. N. A. & Frayling, T. M. Mar 2011 In : Diabetes. 60, 3, p. 1008-1018 11 p.

    Research output: Contribution to journalArticle

  27. Combined effect of inflammatory gene polymorphisms and the risk of ischemic stroke in a prospective cohort of subjects with type 2 diabetes: A Go-DARTS study

    Palmer, C. N. A., Kimber, C. H., Doney, A. S. F., Proia, A. S., Morris, A. D., Gaetani, E., Quarta, M., Smith, R. C. & Pola, R. Nov 2010 In : Diabetes. 59, 11, p. 2945-2948 4 p.

    Research output: Contribution to journalArticle

  28. Hypoglycemia in Type 1 Diabetes

    McCrimmon, R. J. & Sherwin, R. S. Oct 2010 In : Diabetes. 59, 10, p. 2333-2339 7 p.

    Research output: Contribution to journalArticle

  29. The Medial Amygdalar Nucleus: A Novel Glucose-Sensing Region That Modulates the Counterregulatory Response to Hypoglycemia

    Zhou, L., Podolsky, N., Sang, Z., Ding, Y., Fan, X., Tong, Q., Levin, B. E. & McCrimmon, R. J. Oct 2010 In : Diabetes. 59, 10, p. 2646-2652 7 p.

    Research output: Contribution to journalArticle

  30. Hypothalamic FKBP5 Is Induced by Fasting and Leptin Deficiency and Elevated Expression Promotes Obese Phenotypes

    Nguyen, L., Yen, K., Mastaitis, J., Dunn-Meynell, A., Levin, B., Routh, V., McCrimmon, R., Isoda, F., Sherwin, R., Musatov, S. & Mobbs, C. Jun 2010 In : Diabetes. 59, p. A470-A470 1 p.

    Research output: Contribution to journalBook/Film/Article review

  31. Influence of Insulin in the Ventromedial Hypothalamus on Pancreatic Glucagon Secretion In Vivo

    Paranjape, S. A., Chan, O., Zhu, W., Horblitt, A. M., McNay, E. C., Cresswell, J. A., Bogan, J. S., McCrimmon, R. J. & Sherwin, R. S. Jun 2010 In : Diabetes. 59, 6, p. 1521-1527 7 p.

    Research output: Contribution to journalArticle

  32. Multimodal Characterization of Brain Responses to Acute Insulin-Induced Hypoglycemia: An In Vivo fMRI and Electrophysiology Study

    Herman, P., Herzog, R., Zhou, L., Sherwin, R., Hyder, F. & McCrimmon, R. Jun 2010 In : Diabetes. 59, p. A213-A213 1 p.

    Research output: Contribution to journalBook/Film/Article review

  33. PPARG, insulin resistance and metformin pharmacogenetics-A GoDARTS study

    Zhou, K., Burch, L., Hattersley, A. T., McCarthy, M. I., Morris, A. D., Palmer, C. N. A. & Pearson, E. R. Jun 2010 In : Diabetes. 59, p. A115-A115 1 p.

    Research output: Contribution to journalBook/Film/Article review

  34. Thiazolidinedione associated fractures are not limited to distal fractures and occur in men as well as women

    Colhoun, H. M. & Scottish Diabet Research Network Epidemiology Group Jun 2010 In : Diabetes. 59, p. A20-A21 2 p.

    Research output: Contribution to journalBook/Film/Article review

  35. Regulation of MAP Kinase-Directed Mitogenic and Protein Kinase B-Mediated Signaling by Cannabinoid Receptor Type 1 in Skeletal Muscle Cells

    Lipina, C., Stretton, C., Hastings, S., Hundal, J. S., Mackie, K., Irving, A. J. & Hundal, H. S. Feb 2010 In : Diabetes. 59, 2, p. 375-385 11 p.

    Research output: Contribution to journalArticle

  36. Ventromedial Hypothalamic Nitric Oxide Production Is Necessary for Hypoglycemia Detection and Counterregulation

    Fioramonti, X., Marsollier, N., Song, Z., Fakira, K. A., Patel, R. M., Brown, S., Duparc, T., Pica-Mendez, A., Sanders, N. M., Knauf, C., Valet, P., McCrimmon, R. J., Beuve, A., Magnan, C. & Routh, V. H. Feb 2010 In : Diabetes. 59, 2, p. 519-528 10 p.

    Research output: Contribution to journalArticle

  37. Novel Insights Into the Etiology of Diabetes From Genome-Wide Association Studies

    Palmer, C. N. A. Nov 2009 In : Diabetes. 58, 11, p. 2444-2447 4 p.

    Research output: Contribution to journalEditorial

  38. Linkage Disequilibrium Mapping of the Replicated Type 2 Diabetes Linkage Signal on Chromosome 1q

    Prokopenko, I. , Zeggini, E. , Hanson, R. L. , Mitchell, B. D. , Rayner, N. W. , Akan, P. , Baier, L. , Das, S. K. , Elliott, K. S. , Fu, M. , Frayling, T. M. , Groves, C. J. , Gwilliam, R. , Scott, L. J. , Voight, B. F. , Hattersley, A. T. , Hu, C. , Morris, A. D. , Ng, M. , Palmer, C. N. A. & 13 others Tello-Ruiz, M., Vaxillaire, M., Wang, C., Stein, L., Chan, J., Jia, W., Froguel, P., Elbein, S. C., Deloukas, P., Bogardus, C., Shuldiner, A. R., McCarthy, M. I. & Int Type 2 Diabet 1q Consortium Jul 2009 In : Diabetes. 58, 7, p. 1704-1709 6 p.

    Research output: Contribution to journalArticle

  39. Activation of EphA5 Receptors in the Ventromedial Hypothalemus(VMH) Stimulates the Counterregulatory Response to Acute Hypoglycemia

    Szepietowska, B., Zhu, W., Chan, O., Paran-Jape, S., Zhou, L., Mccrimmon, R. J. & Sherwin, R. S. Jun 2009 In : Diabetes. 58, p. A169-A169 1 p.

    Research output: Contribution to journalBook/Film/Article review

  40. Insulin Acts in the VMH To Suppress Pancreatic Glucagon Secretion

    Paranjape, S. A., Chan, O., Zhu, W., Horblitt, A., McCrimmon, R. & Sherwin, R. Jun 2009 In : Diabetes. 58, p. A34-A34 1 p.

    Research output: Contribution to journalBook/Film/Article review

  41. Medial Amygadalar Nucleus, a Novel Limbic Glu - cosensing Region in Rodent, Modulates Counterregulatory Hormone Response to Hypoglycemia

    Zhou, L., Podolsky, N., Sang, Z., Tong, Q., Lowell, B., Vale, W., Levin, B. E. & McCrimmon, R. J. Jun 2009 In : Diabetes. 58, p. A15-A15 1 p.

    Research output: Contribution to journalBook/Film/Article review

  42. Reduced-function SLC22A1 polymorphisms encoding organic cation transporter 1 and glycemic response to metformin: A GoDARTS study

    Zhou, K., Donnelly, L. A., Kimber, C. H., Donnan, P. T., Doney, A. S. F., Leese, G., Hattersley, A. T., McCarthy, M. I., Morris, A. D., Palmer, C. N. A. & Pearson, E. R. Jun 2009 In : Diabetes. 58, 6, p. 1434-1439 6 p.

    Research output: Contribution to journalArticle

  43. The Sources of GABAergic Innervation of the Ventromedial Hypothalamus

    Zhou, L., Chan, O., McCrimmon, R. J. & Sherwin, R. S. Jun 2009 In : Diabetes. 58, p. A14-A15 2 p.

    Research output: Contribution to journalBook/Film/Article review

  44. Medium-Chain Fatty Acids Improve Cognitive Function in Intensively Treated Type 1 Diabetic Patients and Support In Vitro Synaptic Transmission During Acute Hypoglycemia

    Page, K. A., Williamson, A., Yu, N., McNay, E. C., Dzuira, J., McCrimmon, R. J. & Sherwin, R. S. May 2009 In : Diabetes. 58, 5, p. 1237-1244 8 p.

    Research output: Contribution to journalArticle

  45. Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data

    Timpson, N. J., Lindgren, C. M., Weedon, M. N., Randall, J., Ouwehand, W. H., Strachan, D. P., Rayner, N. W., Walker, M., Hitman, G. A., Doney, A. S. F., Palmer, C. N. A., Morris, A. D., Hattersley, A. T., Zeggini, E., Frayling, T. M. & McCarthy, M. I. Feb 2009 In : Diabetes. 58, 2, p. 505-510 6 p.

    Research output: Contribution to journalArticle

  46. Amplified Hormonal Counterregulatory Responses to Hypoglycemia in Rats After Systemic Delivery of a SUR-1-Selective K+ Channel Opener?

    Fan, X., Ding, Y., Cheng, H., Gram, D. X., Sherwin, R. S. & McCrimmon, R. J. Dec 2008 In : Diabetes. 57, 12, p. 3327-3334 8 p.

    Research output: Contribution to journalArticle

  47. Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk

    Lango, H., Palmer, C. N. A., Morris, A. D., Zeggini, E., Hattersley, A. T., McCarthy, M. I., Frayling, T. M., Weedon, M. N. & UK Type Diab Genetics Consortium Nov 2008 In : Diabetes. 57, 11, p. 3129-3135 7 p.

    Research output: Contribution to journalArticle

  48. Dual role of hypothalamic nitric oxide (NO) production in the control of the counter-regulatory response to hypoglycemia

    Fioramonti, X., Sayed, N., Marsollier, N., Mccrimmon, R. J., Pica-Mendez, A., Bogorff, D., Tobon, K. E., Smith, P. J., Sherwin, R. S., Sanders, N. M., Magnan, C., Beuve, A. & Routh, V. H. Jun 2008 In : Diabetes. 57, p. A171-A171 1 p.

    Research output: Contribution to journalBook/Film/Article review

  49. Insulin signaling in the ventromedial hypothalamus (VMH) regulates glucagon secretion during Eu- and hypoglycemia

    Paranjape, S. A., Chan, O., Zhu, W., Wang, A., Fan, X., Mccrimmon, R. & Sherwin, R. Jun 2008 In : Diabetes. 57, p. A39-A40 2 p.

    Research output: Contribution to journalBook/Film/Article review

  50. Medium chain triglycerides improve memory performance during acute hypoglycemia in intensively treated type 1 diabetics

    Page, K. A., McCrimmon, R., Yu, N., Dziura, J. & Sherwin, R. Jun 2008 In : Diabetes. 57, p. A5-A5 1 p.

    Research output: Contribution to journalBook/Film/Article review

  51. Orexin mediates feeding, but not counter regulatory hormonal responses to acute hypoglycemia

    Zhou, L., Sang, Z., Brown, S., Fan, X. & Mccrimmon, R. Jun 2008 In : Diabetes. 57, p. A39-A39 1 p.

    Research output: Contribution to journalBook/Film/Article review

  52. Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

    Freathy, R. M. , Timpson, N. J. , Lawlor, D. A. , Pouta, A. , Ben-Shlomo, Y. , Ruokonen, A. , Ebrahim, S. , Shields, B. , Zeggini, E. , Weedon, M. N. , Lindgren, C. M. , Lango, H. , Melzer, D. , Ferrucci, L. , Paolisso, G. , Neville, M. J. , Karpe, F. , Palmer, C. N. A. , Morris, A. D. , Elliott, P. & 5 others Jarvelin, M-R., Smith, G. D., McCarthy, M. I., Hattersley, A. T. & Frayling, T. M. May 2008 In : Diabetes. 57, 5, p. 1419-1426 8 p.

    Research output: Contribution to journalArticle

  53. Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory reponses after antecedent Hypoglycemia

    Chan, O., Cheng, H., Herzog, R., Czyzyk, D., Zhu, W., Wang, A., McCrimmon, R. J., Seashore, M. R. & Sherwin, R. S. May 2008 In : Diabetes. 57, 5, p. 1363-1370 8 p.

    Research output: Contribution to journalArticle

  54. Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia

    McCrimmon, R. J., Shaw, M., Fan, X., Cheng, H., Ding, Y., Vella, M. C., Zhou, L., Mcnay, E. C. & Sherwin, R. S. Feb 2008 In : Diabetes. 57, 2, p. 444-450 7 p.

    Research output: Contribution to journalArticle

  55. Identification of small compounds that mimic insulin action on the transcription factor FOXO1a

    Cameron, A., Anton, S., Reetoo, N., Melville, L., Houston, N., Dayal, S., McDougall, G., Stewart, D. & Rena, G. 2008 In : Diabetes. 57, Suppl., p. A699-A700 2 p.

    Research output: Contribution to journalMeeting abstract

  56. Characterization of a protein kinase B inhibitor in vitro and in insulin-treated liver cells

    Logie, L., Ruiz-Alcaraz, A. J., Keane, M., Woods, Y. L., Bain, J., Marquez, R., Alessi, D. R. & Sutherland, C. Sep 2007 In : Diabetes. 56, 9, p. 2218-2227 10 p.

    Research output: Contribution to journalArticle

  57. Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study

    Pearson, E. R., Donnelly, L. A., Kimber, C., Whitley, A., Doney, A. S. F., McCarthy, M. I., Hattersley, A. T., Morris, A. D. & Palmer, C. N. A. Aug 2007 In : Diabetes. 56, 8, p. 2178-2182 5 p.

    Research output: Contribution to journalArticle

  58. A role for uncoupling proteins in neuroprotection following recurrent hypoglycemia?

    McCrimmon, R., Andrews, Z., Coppola, A., Cheng, H., Sherwin, R. & Diano, S. Jun 2007 In : Diabetes. 56, Suppl 1, p. A166-A166 1 p., 626-P

    Research output: Contribution to journalArticle

  59. Acute hypoglycemia induces activated neurons in the lateral hypothalamus of the brain and in the intermediolateral cell column of the spinal cord; while recurrent hypoglycemia blunts them

    Zhou, L., Fan, X., Ding, Y., Zhu, W., Chan, O., Vella, M. C., Sherwin, R. S. & McCrimmon, R. J. Jun 2007 In : Diabetes. 56, Suppl 1, p. A101-A101 1 p., 385-OR

    Research output: Contribution to journalArticle

  60. Role of VMH glutamate in counterregulatory response to hypoglycemia

    McCrimmon, R., Tong, Q., Wang, A., Zhou, L., Lowell, B. B. & Sherwin, R. Jun 2007 In : Diabetes. 56, Suppl 1, p. A99-A99 1 p., 379-OR

    Research output: Contribution to journalArticle

  61. 5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside acutely stimulates skeletal muscle 2-deoxyglucose uptake in healthy men

    Cuthbertson, D. J., Babraj, J. A., Mustard, K. J. W., Towler, M. C., Green, K. A., Wackerhage, H., Leese, G. P., Baar, K., Thomason-Hughes, M., Sutherland, C., Hardie, D. G. & Rennie, M. J. 2007 In : Diabetes. 56, 8, p. 2078-2084 7 p.

    Research output: Contribution to journalArticle

  62. Activation of AMP-activated protein kinase within the ventromedial hypothalamus amplifies counterregulatory hormone responses in rats with defective counterregulation

    McCrimmon, R. J., Fan, X., Cheng, H., McNay, E., Chan, O., Shaw, M., Ding, Y., Zhu, W. & Sherwin, R. S. Jun 2006 In : Diabetes. 55, 6, p. 1755-1760 6 p.

    Research output: Contribution to journalArticle

  63. AMP-activated protein kinase (AMPK): A key mediator of hypoglycemia-sensing in the ventromedial hypothalamus (VMH)

    McCrimmon, R. J., Shaw, M., Fan, X., Cheng, H., Ding, Y., Wang, A. & Sherwin, R. S. Jun 2006 In : Diabetes. 55, Suppl 1, p. A15-A15 1 p., 62-OR

    Research output: Contribution to journalArticle

  64. ATP-sensitive potassium channels in the ventromedial hypothalamus regulate GABA release during hypoglycemia

    Chan, O., Zhu, W., Wang, A., McCrimmon, R. J. & Sherwin, R. S. Jun 2006 In : Diabetes. 55, Suppl 1, p. A146-A147 2 p., 616-P

    Research output: Contribution to journalArticle

  65. Effect of acute and recurrent hypoglycemia on regional changes in brain glycogen concentration

    Herzog, R. I., McNay, E. C., McCrimmon, R., Yeckel, C. W., Zhu, W., Ding, Y., Wang, A., Fan, X. & Sherwin, R. S. Jun 2006 In : Diabetes. 55, Suppl 1, p. A149-A149 1 p., 626-P

    Research output: Contribution to journalArticle

  66. Modulation of type 1 corticotrophin releasing factor receptors (CRF-R1) in the ventromedial hypothalamus (VMR) affects hypoglycemia-induced hormonal counterregulation

    Cheng, H., Wang, A., Zhu, W., Fan, X., Ding, Y., Tang, C., Zhong, M., Sherwin, R. & McCrimmon, R. Jun 2006 In : Diabetes. 55, Suppl 1, p. A16-A16 1 p., 65-OR

    Research output: Contribution to journalArticle

  67. Systemic insulin resistance alters cognitive and metabolic responses to intrahippocampal insulin

    McNay, E. C., Herzog, R., McCrimmon, R. J. & Sherwin, R. S. Jun 2006 In : Diabetes. 55, Suppl 1, p. A295-A295 1 p., 1254-P

    Research output: Contribution to journalArticle

  68. Antecedent hypercortisolemia is not primarily responsible for generating hypoglycemia-associated autonomic failure

    Goldberg, P. A., Weiss, R., McCrimmon, R. J., Hintz, E. V., Dziura, J. D. & Sherwin, R. S. Apr 2006 In : Diabetes. 55, 4, p. 1121-1126 6 p.

    Research output: Contribution to journalArticle

  69. Blockade of GABAA receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia

    Chan, O., Zhu, W., Ding, Y., McCrimmon, R. J. & Sherwin, R. S. Apr 2006 In : Diabetes. 55, 4, p. 1080-1087 8 p.

    Research output: Contribution to journalArticle

  70. Cognitive and neural hippocampal effects of long-term moderate recurrent hypoglycemia

    McNay, E. C., Williamson, A., McCrimmon, R. J. & Sherwin, R. S. Apr 2006 In : Diabetes. 55, 4, p. 1088-1095 8 p.

    Research output: Contribution to journalArticle

  71. Contrasting insulin sensitivity of endogenous glucose production rate in subjects with hepatocyte nuclear factor-1β and -1α mutations

    Brackenridge, A., Pearson, E. R., Shojaee-Moradie, F., Hattersley, A. T., Russell-Jones, D. & Umpleby, A. M. Feb 2006 In : Diabetes. 55, 2, p. 405-411 7 p.

    Research output: Contribution to journalArticle

  72. Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats

    McCrimmon, R. J., Evans, M. L., Fan, X., McNay, E. C., Chan, O., Ding, Y., Zhu, W., Gram, D. X. & Sherwin, R. S. Nov 2005 In : Diabetes. 54, 11, p. 3169-3174 6 p.

    Research output: Contribution to journalArticle

  73. Insulin-stimulated glucose uptake does not require p38 mitogen-activated protein kinase in adipose tissue or skeletal muscle

    Turban, S., Beardmore, V. A., Carr, J. M., Sakamoto, K., Hajduch, E., Arthur, J. S. C. & Hundal, H. S. Nov 2005 In : Diabetes. 54, 11, p. 3161-3168 8 p.

    Research output: Contribution to journalArticle

  74. Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses

    Evans, M. L., McCrimmon, R. J., Flanagan, D. E., Keshavarz, T., Fan, X., McNay, E. C., Jacob, R. J. & Sherwin, R. S. Oct 2004 In : Diabetes. 53, 10, p. 2542-2551 10 p.

    Research output: Contribution to journalArticle

  75. Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus

    McCrimmon, R. J., Fan, X., Ding, Y., Zhu, W., Jacob, R. J. & Sherwin, R. S. Aug 2004 In : Diabetes. 53, 8, p. 1953-1958 6 p.

    Research output: Contribution to journalArticle

  76. Initial characterization of a rat model of diabetic nephropathy

    Nobrega, M. A., Fleming, S., Roman, R. J., Shiozawa, M., Schlick, N., Lazar, J. & Jacob, H. J. 2004 In : Diabetes. 53, 3, p. 735-42 8 p.

    Research output: Contribution to journalArticle

  77. Disruption of the striated muscle glycogen targeting subunit PPP1R3A of protein phosphatase 1 leads to increased weight gain, fat deposition, and development of insulin resistance

    Delibegovic, M., Armstrong, C. G., Dobbie, L., Watt, P. W., Smith, A. J. H. & Cohen, T. Mar 2003 In : Diabetes. 52, 3, p. 596-604 9 p.

    Research output: Contribution to journalArticle

  78. Cognitive ability and brain structure in type 1 diabetes: relation to microangiopathy and preceding severe hypoglycemia

    Ferguson, S. C., Blane, A., Perros, P., McCrimmon, R. J., Best, J. J. K., Wardlaw, J., Deary, I. J. & Frier, B. M. Jan 2003 In : Diabetes. 52, 1, p. 149-156 8 p.

    Research output: Contribution to journalArticle

  79. Relationship of phospholipid transfer protein activity to HDL and apolipoprotein B–Containing lipoproteins in subjects with and without type 1 diabetes

    Colhoun, H. M., Taskinen, M-R., Otvos, J. D., van den Berg, P., O'Connor, J. & Van Tol, A. Nov 2002 In : Diabetes. 51, 11, p. 3300-3305 6 p.

    Research output: Contribution to journalArticle

  80. Lipoprotein subclasses and particle sizes and their relationship with coronary artery calcification in men and women with and without type 1 diabetes

    Colhoun, H. M., Otvos, J. D., Rubens, M. B., Taskinen, M. R., Underwood, S. R. & Fuller, J. H. Jun 2002 In : Diabetes. 51, 6, p. 1949-56 8 p.

    Research output: Contribution to journalArticle

  81. Human skeletal muscle expresses a glycogen-targeting subunit of PP1 that is identical to the insulin-sensitive glycogen-targeting subunit G(L) of liver

    Munro, S., Cuthbertson, D. J. R., Cunningham, J., Sales, M. & Cohen, P. T. W. 2002 In : Diabetes. 51, 3, p. 591-598 8 p.

    Research output: Contribution to journalArticle

  82. Lipid transfer protein activities in type 1 diabetic patients without renal failure and nondiabetic control subjects and their association with coronary artery calcification

    Colhoun, H. M., Scheek, L. M., Rubens, M. B., Van Gent, T., Underwood, S. R., Fuller, J. H. & Van Tol, A. Mar 2001 In : Diabetes. 50, 3, p. 652-659 8 p.

    Research output: Contribution to journalArticle

  83. Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups

    Dinkova-Kostova, A. T., Massiah, M. A., Bozak, R. E., Hicks, R. J. & Talalay, P. Mar 2001 In : Diabetes. 98, 6, p. 3404-3409 6 p.

    Research output: Contribution to journalArticle

  84. Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphoenolpyruvate carboxykinase gene expression

    Lochhead, P. A., Coghlan, M., Rice, S. Q. J. & Sutherland, C. 2001 In : Diabetes. 50, 5, p. 937-946 10 p.

    Research output: Contribution to journalArticle

  85. 5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase

    Lochhead, P. A., Salt, I. P., Walker, K. S., Hardie, D. G. & Sutherland, C. 2000 In : Diabetes. 49, 6, p. 896-903 8 p.

    Research output: Contribution to journalArticle

  86. Oxidative and chemical stress mimic insulin by selectively inhibiting the expression of phosphoenolpyruvate carboxykinase in hepatoma cells

    Sutherland, C., Tebbey, P. W. & Granner, D. K. 1997 In : Diabetes. 46, 1, p. 17-22 6 p.

    Research output: Contribution to journalArticle

  87. ATP-sensitive K+ channels in pancreatic β-cells: Spare-channel hypothesis

    Cook, D. L., Satin, L. S., Ashford, M. L. J. & Hales, C. N. May 1988 In : Diabetes. 37, 5, p. 495-498 4 p.

    Research output: Contribution to journalArticle

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