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Diabetes

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  1. Glucose-6-phosphate-mediated activation of liver glycogen synthase plays a key role in hepatic glycogen synthesis

    von Wilamowitz-Moellendorff, A., Hunter, R. W., García-Rocha, M., Kang, L., López-Soldado, I., Lantier, L., Patel, K., Peggie, M. W., Martínez-Pons, C., Voss, M., Calbó, J., Cohen, P. T. W., Wasserman, D. H., Guinovart, J. J. & Sakamoto, K. Dec 2013 In : Diabetes. 62, 12, p. 4070-4082 13 p.

    Research output: Contribution to journalArticle

  2. Mitochondrial Substrate Availability and its Role in Lipid-Induced Insulin Resistance and Proinflammatory Signalling in Skeletal Muscle

    Lipina, C., Macrae, K., Suhm, T., Weigert, C., Blachnio-Zabielska, A., Baranowksi, M., Gorski, J., Burgess, K. & Hundal, H. S. Oct 2013 In : Diabetes. 62, 10, p. 3426-3436 11 p.

    Research output: Contribution to journalArticle

  3. AMPK: a target for drugs and natural products with effects on both diabetes and cancer

    Hardie, D. G. Jul 2013 In : Diabetes. 62, 7, p. 2164-2172 9 p.

    Research output: Contribution to journalArticle

  4. Biomarkers for type 2 diabetes and impaired fasting glucose using a non-targeted metabolomics approach

    Menni, C. , Fauman, E. , Erte, I. , Perry, J. R. B. , Kastenmüller, G. , Shin, S-Y. , Petersen, A-K. , Hyde, C. , Psatha, M. , Ward, K. J. , Yuan, W. , Milburn, M. , Palmer, C. N. A. , Frayling, T. M. , Trimmer, J. , Bell, J. T. , Gieger, C. , Mohney, R. , Brosnan, M. J. , Suhre, K. & 2 others Soranzo, N. & Spector, T. D. 2013 In : Diabetes.

    Research output: Contribution to journalArticle

  5. Mendelian randomisation studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes

    Yaghootkar, H. , Lamina, C. , Scott, R. A. , Dastani, Z. , Hivert, M-F. , Warren, L. L. , Stancáková, A. , Buxbaum, S. G. , Lyytikäinen, L-P. , Henneman, P. , Wu, Y. , Cheung, C. Y. Y. , Pankow, J. S. , Jackson, A. U. , Gustafsson, S. , Zhao, J. H. , Ballantyne, C. M. , Xie, W. , Bergman, R. N. , Boehnke, M. & 58 others El Bouazzaoui, F., Collins, F. S., Dunn, S. H., Dupuis, J., Forouhi, N. G., Gillson, C., Hattersley, A. T., Hong, J., Kähönen, M., Kuusisto, J., Kedenko, L., Kronenberg, F., Doria, A., Assimes, T. L., Ferrannini, E., Hansen, T., Hao, K., Häring, H., Knowles, J. W., Lindgren, C. M., Nolan, J. J., Paananen, J., Pedersen, O., Quertermous, T., Smith, U., the GENESIS consortium, the RISC consortium, Lehtimäki, T., Liu, C-T., Loos, R. J. F., McCarthy, M. I., Morris, A. D., Vasan, R. S., Spector, T. D., Teslovich, T. M., Tuomilehto, J., Willems van Dijk, K., Viikari, J. S., Zhu, N., Langenberg, C., Ingelsson, E., Semple, R. K., Sinaiko, A. R., Palmer, C. N. A., Walker, M., Lam, K. S. L., Paulweber, B., Mohlke, K. L., van Duijn, C., Raitakari, O. T., Bidulescu, A., Wareham, N. J., Laakso, M., Waterworth, D. M., Lawlor, D. A., Meigs, J. B., Richards, J. B. & Frayling, T. M. 2013 In : Diabetes.

    Research output: Contribution to journalArticle

  6. The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway

    't Hart, L. M. , Fritsche, A. , Nijpels, G. , van Leeuwen, N. , Donnelly, L. A. , Dekker, J. M. , Alssema, M. , Fadista, J. , Carlotti, F. , Gjesing, A. P. , Palmer, C. N. A. , van Haeften, T. W. , Herzberg-Schäfer, S. A. , Simonis-Bik, A. M. C. , Houwing-Duistermaat, J. J. , Helmer, Q. , Deelen, J. , Guigas, B. , Hansen, T. , Machicao, F. & 14 others Willemsen, G., Heine, R. J., Kramer, M. H. H., Holst, J. J., de Koning, E. J. P., Häring, H-U., Pedersen, O., Groop, L., de Geus, E. J. C., Slagboom, P. E., Boomsma, D. I., Eekhoff, E. M. W., Pearson, E. R. & Diamant, M. 2013 In : Diabetes.

    Research output: Contribution to journalArticle

  7. Cellular Responses to the Metal-Binding Properties of Metformin

    Logie, L., Harthill, J., Patel, K., Bacon, S., Hamilton, D. L., Macrae, K., McDougall, G., Wang, H-H., Xue, L., Jiang, H., Sakamoto, K., Prescott, A. R. & Rena, G. Jun 2012 In : Diabetes. 61, 6, p. 1423-1433 11 p.

    Research output: Contribution to journalArticle

  8. Deep Resequencing Unveils Genetic Architecture of ADIPOQ and Identifies a Novel Low-Frequency Variant Strongly Associated With Adiponectin Variation

    Warren, L. L. , Li, L. , Nelson, M. R. , Ehm, M. G. , Shen, J. , Fraser, D. J. , Aponte, J. L. , Nangle, K. L. , Slater, A. J. , Woollard, P. M. , Hall, M. D. , Topp, S. D. , Yuan, X. , Cardon, L. R. , Chissoe, S. L. , Mooser, V. , Morris, A. D. , Palmer, C. N. A. , Perry, J. R. , Frayling, T. M. & 2 others Whittaker, J. C. & Waterworth, D. M. May 2012 In : Diabetes. 61, 5, p. 1297-1301 5 p.

    Research output: Contribution to journalArticle

  9. Total soluble and endogenous secretory receptor for advanced glycation end products as predictive biomarkers of coronary heart disease risk in patients with type 2 Diabetes: an analysis from the CARDS trial

    Colhoun, H. M., Betteridge, D. J., Durrington, P., Hitman, G., Neil, A., Livingstone, S., Charlton-Menys, V., Bao, W., DeMicco, D. A., Preston, G. M., Deshmukh, H., Tan, K. & Fuller, J. H. Sep 2011 In : Diabetes. 60, 9, p. 2379-2385 7 p.

    Research output: Contribution to journalArticle

  10. Deletion of Lkb1 in Pro-Opiomelanocortin Neurons Impairs Peripheral Glucose Homeostasis in Mice

    Ashford, M. L. & 22 others Claret, M., Smith, M. A., Knauf, C., Al-Qassab, H., Woods, A., Heslegrave, A., Piipari, K., Emmanuel, J. J., Colom, A., Valet, P., Cani, P. D., Begum, G., White, A., Mucket, P., Peters, M., Mizuno, K., Batterham, R. L., Giese, K. P., Ashworth, A., Burcelin, R., Carling, D. & Withers, D. J. Mar 2011 In : Diabetes. 60, 3, p. 735-745 11 p.

    Research output: Contribution to journalArticle

  11. Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance.

    De Silva, N. M. G. , Freathy, R. M. , Palmer, T. M. , Donnelly, L. A. , Luan, J. , Gaunt, T. , Langenberg, C. , Weedon, M. N. , Shields, B. , Knight, B. A. , Ward, K. J. , Sandhu, M. S. , Harbord, R. M. , McCarthy, M. I. , Smith, G. D. , Ebrahim, S. , Hattersley, A. T. , Wareham, N. , Lawlor, D. A. , Morris, A. D. & 2 others Palmer, C. N. A. & Frayling, T. M. Mar 2011 In : Diabetes. 60, 3, p. 1008-1018 11 p.

    Research output: Contribution to journalArticle

  12. Combined effect of inflammatory gene polymorphisms and the risk of ischemic stroke in a prospective cohort of subjects with type 2 diabetes: A Go-DARTS study

    Palmer, C. N. A., Kimber, C. H., Doney, A. S. F., Proia, A. S., Morris, A. D., Gaetani, E., Quarta, M., Smith, R. C. & Pola, R. Nov 2010 In : Diabetes. 59, 11, p. 2945-2948 4 p.

    Research output: Contribution to journalArticle

  13. Hypoglycemia in Type 1 Diabetes

    McCrimmon, R. J. & Sherwin, R. S. Oct 2010 In : Diabetes. 59, 10, p. 2333-2339 7 p.

    Research output: Contribution to journalArticle

  14. The Medial Amygdalar Nucleus: A Novel Glucose-Sensing Region That Modulates the Counterregulatory Response to Hypoglycemia

    Zhou, L., Podolsky, N., Sang, Z., Ding, Y., Fan, X., Tong, Q., Levin, B. E. & McCrimmon, R. J. Oct 2010 In : Diabetes. 59, 10, p. 2646-2652 7 p.

    Research output: Contribution to journalArticle

  15. Hypothalamic FKBP5 Is Induced by Fasting and Leptin Deficiency and Elevated Expression Promotes Obese Phenotypes

    Nguyen, L., Yen, K., Mastaitis, J., Dunn-Meynell, A., Levin, B., Routh, V., McCrimmon, R., Isoda, F., Sherwin, R., Musatov, S. & Mobbs, C. Jun 2010 In : Diabetes. 59, p. A470-A470 1 p.

    Research output: Contribution to journalBook/Film/Article review

  16. Influence of Insulin in the Ventromedial Hypothalamus on Pancreatic Glucagon Secretion In Vivo

    Paranjape, S. A., Chan, O., Zhu, W., Horblitt, A. M., McNay, E. C., Cresswell, J. A., Bogan, J. S., McCrimmon, R. J. & Sherwin, R. S. Jun 2010 In : Diabetes. 59, 6, p. 1521-1527 7 p.

    Research output: Contribution to journalArticle

  17. Multimodal Characterization of Brain Responses to Acute Insulin-Induced Hypoglycemia: An In Vivo fMRI and Electrophysiology Study

    Herman, P., Herzog, R., Zhou, L., Sherwin, R., Hyder, F. & McCrimmon, R. Jun 2010 In : Diabetes. 59, p. A213-A213 1 p.

    Research output: Contribution to journalBook/Film/Article review

  18. PPARG, insulin resistance and metformin pharmacogenetics-A GoDARTS study

    Zhou, K., Burch, L., Hattersley, A. T., McCarthy, M. I., Morris, A. D., Palmer, C. N. A. & Pearson, E. R. Jun 2010 In : Diabetes. 59, p. A115-A115 1 p.

    Research output: Contribution to journalBook/Film/Article review

  19. Thiazolidinedione associated fractures are not limited to distal fractures and occur in men as well as women

    Colhoun, H. M. & Scottish Diabet Research Network Epidemiology Group Jun 2010 In : Diabetes. 59, p. A20-A21 2 p.

    Research output: Contribution to journalBook/Film/Article review

  20. Regulation of MAP Kinase-Directed Mitogenic and Protein Kinase B-Mediated Signaling by Cannabinoid Receptor Type 1 in Skeletal Muscle Cells

    Lipina, C., Stretton, C., Hastings, S., Hundal, J. S., Mackie, K., Irving, A. J. & Hundal, H. S. Feb 2010 In : Diabetes. 59, 2, p. 375-385 11 p.

    Research output: Contribution to journalArticle

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