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Drug Metabolism and Disposition

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  1. A role for cytochrome b5 in the in vivo disposition of anti-cancer and cytochrome P450 probe drugs in mice

    Henderson, C. J., McLaughlin, L. A., Finn, R. D., Ronseaux, S., Kapelyukh, Y. & Wolf, C. R. Jan 2014 In : Drug Metabolism and Disposition. 42, 1, p. 70-77 8 p.

    Research output: Contribution to journalArticle

  2. Deletion of 30 murine cytochrome p450 genes results in viable mice with compromised drug metabolism

    Scheer, N., McLaughlin, L. A., Rode, A., MacLeod, A. K., Henderson, C. J. & Wolf, C. R. 2014 In : Drug Metabolism and Disposition. 42, 6, p. 1022-1030 9 p.

    Research output: Contribution to journalArticle

  3. NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology

    Riddick, D. S., Ding, X., Wolf, C. R., Porter, T. D., Pandey, A. V., Zhang, Q-Y., Gu, J., Finn, R. D., Ronseaux, S., McLaughlin, L. A., Henderson, C. J., Zou, L. & Flück, C. E. Jan 2013 In : Drug Metabolism and Disposition. 41, 1, p. 12-23 12 p.

    Research output: Contribution to journalArticle

  4. Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1

    McNeilly, A. D., Woods, J. A., Ibbotson, S. H., Wolf, C. R. & Smith, G. Feb 2012 In : Drug Metabolism and Disposition. 40, 2, p. 283-289 7 p.

    Research output: Contribution to journalArticle

  5. Generation and characterization of a novel multidrug resistance protein 2 humanized mouse line

    Scheer, N., Balimane, P., Hayward, M. D., Buechel, S., Kauselmann, G. & Wolf, C. R. 2012 In : Drug Metabolism and Disposition. 40, 11, p. 2212-2218 7 p.

    Research output: Contribution to journalArticle

  6. Neonatal development of hepatic UGT1A9: implications of pediatric pharmacokinetics

    Miyagi, S. J., Milne, A. M., Coughtrie, M. W. H. & Collier, A. C. 2012 In : Drug Metabolism and Disposition. 40, 7, p. 1321-1327 7 p.

    Research output: Contribution to journalArticle

  7. Effect of hepatic cytochrome P450 (P450) oxidoreductase deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 reductase conditional null mice

    Arlt, V. M., Singh, R., Stiborova, M., da Costa, G. G., Frei, E., Evans, J. D., Farmer, P. B., Wolf, C. R., Henderson, C. J. & Phillips, D. H. Dec 2011 In : Drug Metabolism and Disposition. 39, 12, p. 2169-2173 5 p.

    Research output: Contribution to journalArticle

  8. The Imidazoacridinone Antitumor Drug, C-1311, Is Metabolized by Flavin Monooxygenases but Not by Cytochrome P450s

    Potega, A., Dabrowska, E., Niemira, M., Kot-Wasik, A., Ronseaux, S., Henderson, C. J., Wolf, C. R. & Mazerska, Z. Aug 2011 In : Drug Metabolism and Disposition. 39, 8, p. 1423-1432 10 p.

    Research output: Contribution to journalArticle

  9. A novel method for the immunoquantification of UDP-glucuronosyltransferases in human tissue

    Milne, A. M., Burchell, B. & Coughtrie, M. W. H. 2011 In : Drug Metabolism and Disposition. 39, 12, p. 2258-2263 6 p.

    Research output: Contribution to journalArticle

  10. In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in Mice

    Scheer, N., Ross, J., Kapelyukh, Y., Rode, A. & Wolf, C. R. Jul 2010 In : Drug Metabolism and Disposition. 38, 7, p. 1046-1053 8 p.

    Research output: Contribution to journalArticle

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