Drug Metabolism and Disposition

Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1

McNeilly, A. D., Woods, J. A., Ibbotson, S. H., Wolf, C. R. & Smith, G. Feb-2012 In : Drug Metabolism and Disposition. 40, 2, p. 283-289, 7 p.

Research output: Contribution to journal › Article

Generation and characterization of a novel multidrug resistance protein 2 humanized mouse line

Scheer, N., Balimane, P., Hayward, M. D., Buechel, S., Kauselmann, G. & Wolf, C. R. 2012 In : Drug Metabolism and Disposition. 40, 11, p. 2212-2218, 7 p.

Research output: Contribution to journal › Article

Neonatal development of hepatic UGT1A9: implications of pediatric pharmacokinetics

Miyagi, S. J., Milne, A. M., Coughtrie, M. W. H. & Collier, A. C. 2012 In : Drug Metabolism and Disposition. 40, 7, p. 1321-1327, 7 p.

Research output: Contribution to journal › Article

Effect of hepatic cytochrome P450 (P450) oxidoreductase deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 reductase conditional null mice

Arlt, V. M., Singh, R., Stiborova, M., da Costa, G. G., Frei, E., Evans, J. D., Farmer, P. B., Wolf, C. R., Henderson, C. J. & Phillips, D. H. Dec-2011 In : Drug Metabolism and Disposition. 39, 12, p. 2169-2173, 5 p.

Research output: Contribution to journal › Article

The Imidazoacridinone Antitumor Drug, C-1311, Is Metabolized by Flavin Monooxygenases but Not by Cytochrome P450s

Potega, A., Dabrowska, E., Niemira, M., Kot-Wasik, A., Ronseaux, S., Henderson, C. J., Wolf, C. R. & Mazerska, Z. Aug-2011 In : Drug Metabolism and Disposition. 39, 8, p. 1423-1432, 10 p.

Research output: Contribution to journal › Article

A novel method for the immunoquantification of UDP-glucuronosyltransferases in human tissue

Milne, A. M., Burchell, B. & Coughtrie, M. W. H. 2011 In : Drug Metabolism and Disposition. 39, 12, p. 2258-2263, 6 p.

Research output: Contribution to journal › Article

In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in Mice

Scheer, N., Ross, J., Kapelyukh, Y., Rode, A. & Wolf, C. R. Jul-2010 In : Drug Metabolism and Disposition. 38, 7, p. 1046-1053, 8 p.

Research output: Contribution to journal › Article

Expression and Localization of Rat Aldo-Keto Reductases and Induction of the 1B13 and 1D2 Isoforms by Phenolic Antioxidants

MacLeod, A. K., Kelly, V. P., Higgins, L. G., Kelleher, M. O., Price, S. A., Bigley, A. L., Betton, G. R. & Hayes, J. D. Feb-2010 In : Drug Metabolism and Disposition. 38, 2, p. 341-346, 6 p.

Research output: Contribution to journal › Article

Quantitative evaluation of the expression and activity of five major sulfotransferases (SULTs) in human tissues: the SULT "pie"

Riches, Z., Stanley, E. L., Bloomer, J. C. & Coughtrie, M. W. H. Nov-2009 In : Drug Metabolism and Disposition. 37, 11, p. 2255-2261, 7 p.

Research output: Contribution to journal › Article

Receptor occupancy and brain free fraction

Watson, J., Wright, S., Lucas, A., Clarke, K. L., Viggers, J., Cheetham, S., Jeffrey, P., Porter, R. & Read, K. D. Apr-2009 In : Drug Metabolism and Disposition. 37, 4, p. 753-760, 8 p.

Research output: Contribution to journal › Article