Discovery - University of Dundee - Online Publications

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Drug Metabolism and Disposition

  1. Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening

    McLaughlin, L. A., Dickmann, L. J., Wolf, C. R. & Henderson, C. J. Jul 2008 In : Drug Metabolism and Disposition. 36, 7, p. 1322-1331 10 p.

    Research output: Contribution to journalArticle

  2. Multiple substrate binding by cytochrome P450 3A4: Estimation of the number of bound substrate molecules

    Kapelyukh, Y., Paine, M., Marechal, J-D., Sutcliffe, M. J., Wolf, C. R. & Roberts, G. C. K. Oct 2008 In : Drug Metabolism and Disposition. 36, 10, p. 2136-2144 9 p.

    Research output: Contribution to journalArticle

  3. Receptor occupancy and brain free fraction

    Watson, J., Wright, S., Lucas, A., Clarke, K. L., Viggers, J., Cheetham, S., Jeffrey, P., Porter, R. & Read, K. D. Apr 2009 In : Drug Metabolism and Disposition. 37, 4, p. 753-760 8 p.

    Research output: Contribution to journalArticle

  4. Quantitative evaluation of the expression and activity of five major sulfotransferases (SULTs) in human tissues: the SULT "pie"

    Riches, Z., Stanley, E. L., Bloomer, J. C. & Coughtrie, M. W. H. Nov 2009 In : Drug Metabolism and Disposition. 37, 11, p. 2255-2261 7 p.

    Research output: Contribution to journalArticle

  5. Expression and Localization of Rat Aldo-Keto Reductases and Induction of the 1B13 and 1D2 Isoforms by Phenolic Antioxidants

    MacLeod, A. K., Kelly, V. P., Higgins, L. G., Kelleher, M. O., Price, S. A., Bigley, A. L., Betton, G. R. & Hayes, J. D. Feb 2010 In : Drug Metabolism and Disposition. 38, 2, p. 341-346 6 p.

    Research output: Contribution to journalArticle

  6. In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in Mice

    Scheer, N., Ross, J., Kapelyukh, Y., Rode, A. & Wolf, C. R. Jul 2010 In : Drug Metabolism and Disposition. 38, 7, p. 1046-1053 8 p.

    Research output: Contribution to journalArticle

  7. A novel method for the immunoquantification of UDP-glucuronosyltransferases in human tissue

    Milne, A. M., Burchell, B. & Coughtrie, M. W. H. 2011 In : Drug Metabolism and Disposition. 39, 12, p. 2258-2263 6 p.

    Research output: Contribution to journalArticle

  8. The Imidazoacridinone Antitumor Drug, C-1311, Is Metabolized by Flavin Monooxygenases but Not by Cytochrome P450s

    Potega, A., Dabrowska, E., Niemira, M., Kot-Wasik, A., Ronseaux, S., Henderson, C. J., Wolf, C. R. & Mazerska, Z. Aug 2011 In : Drug Metabolism and Disposition. 39, 8, p. 1423-1432 10 p.

    Research output: Contribution to journalArticle

  9. Effect of hepatic cytochrome P450 (P450) oxidoreductase deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 reductase conditional null mice

    Arlt, V. M., Singh, R., Stiborova, M., da Costa, G. G., Frei, E., Evans, J. D., Farmer, P. B., Wolf, C. R., Henderson, C. J. & Phillips, D. H. Dec 2011 In : Drug Metabolism and Disposition. 39, 12, p. 2169-2173 5 p.

    Research output: Contribution to journalArticle

  10. Generation and characterization of a novel multidrug resistance protein 2 humanized mouse line

    Scheer, N., Balimane, P., Hayward, M. D., Buechel, S., Kauselmann, G. & Wolf, C. R. 2012 In : Drug Metabolism and Disposition. 40, 11, p. 2212-2218 7 p.

    Research output: Contribution to journalArticle

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