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EMBO Journal

  1. The hVPS34-SGK3 pathway counteracts inhibition of the PI3K-Akt to maintain mTORC1 and tumour growth

    Bago, R., Eskelinen, E-L., Castel , P., Crafter, C., Bailey, F. P., Shpiro, N., Baselga, J., Cross, D., Eyers, P. & Alessi, D. 15 Aug 2016 In : EMBO Journal. 35, 16, p. 1721-1843 33 p., e201693929

    Research output: Contribution to journalArticle

  2. Phosphopeptide binding by Sld3 links Dbf4-dependent kinase to MCM replicative helicase activation

    Deegan, T. D., Yeeles, J. T. P. & Diffley, J. F. X. 2016 In : EMBO Journal. 35

    Research output: Contribution to journalArticle

  3. Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis

    Kumar, A., Aguirre, J. D., Condos, T. E. C., Martinez-Torres, R. J., Chaugule, V. K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D. E., Barber, K. R., Shaw, G. S. & Walden, H. 14 Oct 2015 In : EMBO Journal. 34, 20, p. 2506-2521 16 p.

    Research output: Contribution to journalArticle

  4. mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival

    Munson, M. J., Allen, G. F. G., Toth, R., Campbell, D. G., Lucocq, J. M. & Ganley, I. G. 2 Sep 2015 In : EMBO Journal. 34, 17, p. 2272-2290 19 p.

    Research output: Contribution to journalArticle

  5. Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes

    Preston, G. C., Sinclair, L. V., Kaskar, A., Hukelmann, J. L., Navarro, M., Ferrero, I., MacDonald, H. R., Cowling, V. H. & Cantrell, D. A. 4 Aug 2015 In : EMBO Journal. 34, 15, p. 2008-2024 17 p.

    Research output: Contribution to journalArticle

  6. USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses

    Perez-Oliva, A. B., Lachaud, C., Szyniarowski, P., Muñoz, I., Macartney, T., Hickson, I., Rouse, J. & Alessi, D. R. 3 Feb 2015 In : EMBO Journal. 34, 3, p. 326-343 18 p.

    Research output: Contribution to journalArticle

  7. Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1

    Lai, Y-C., Kondapalli, C., Lehneck, R., Procter, J. B., Dill, B. D., Woodroof, H. I., Gourlay, R., Peggie, M., Macartney, T. J., Corti, O., Corvol, J-C., Campbell, D. G., Itzen, A., Trost, M. & Muqit, M. M. K. 2015 In : EMBO Journal. 22 p.

    Research output: Contribution to journalArticle

  8. A cyclic GMP-dependent signalling pathway regulates bacterial phytopathogenesis

    An, S-Q., Chin, K-H., Febrer, M., McCarthy, Y., Yang, J-G., Liu, C-L., Swarbreck, D., Rogers, J., Dow, J. M., Chou, S-H. & Ryan, R. P. 11 Sep 2013 In : EMBO Journal. 32, 18, p. 2430-2438

    Research output: Contribution to journalArticle

  9. Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease

    Sharifi, R. , Morra, R. , Appel, C. D. , Tallis, M. , Chioza, B. , Jankevicius, G. , Simpson, M. A. , Matic, I. , Ozkan, E. , Golia, B. , Schellenberg, M. J. , Weston, R. , Williams, J. G. , Rossi, M. N. , Galehdari, H. , Krahn, J. , Wan, A. , Trembath, R. C. , Crosby, A. H. & 6 others Ahel, D., Hay, R., Ladurner, A. G., Timinszky, G., Williams, R. S. & Ahel, I. 2 May 2013 In : EMBO Journal. 32, 9, p. 1225-1237 13 p.

    Research output: Contribution to journalArticle

  10. PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development

    Venigalla, R. K. C., McGuire, V. A., Clarke, R., Patterson-Kane, J. C., Najafov, A., Toth, R., McCarthy, P. C., Simeons, F., Stojanovski, L. & Arthur, J. S. C. 3 Apr 2013 In : EMBO Journal. 32, 7, p. 1008-22 15 p.

    Research output: Contribution to journalArticle

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