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  1. PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development

    Venigalla, R. K. C., McGuire, V. A., Clarke, R., Patterson-Kane, J. C., Najafov, A., Toth, R., McCarthy, P. C., Simeons, F., Stojanovski, L. & Arthur, J. S. C. 3-Apr-2013 In : EMBO Journal. 32, 7, p. 1008-22, 15 p.

    Research output: Contribution to journalArticle

  2. A sweet TET-a-tete-synergy of TET proteins and O-GlcNAc transferase in transcription

    Mariappa, D., Pathak, S. & van Aalten, D. M. F. 2013 In : EMBO Journal. 32, 5, p. 612-613, 2 p.

    Research output: Contribution to journalEditorial

  3. Sperm are promiscuous and CatSper is to blame...

    Barratt, C. L. R. & Publicover, S. J. 4-Apr-2012 In : EMBO Journal. 31, 7, p. 1624-1626, 3 p.

    Research output: Contribution to journalArticle

  4. O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release

    Pathak, S., Borodkin, V. S., Albarbarawi, O., Campbell, D. G., Ibrahim, A. & van Aalten, D. M. F. 21-Mar-2012 In : EMBO Journal. 31, 6, p. 1394-1404, 11 p.

    Research output: Contribution to journalArticle

  5. The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains

    Ryan, D. P., Sundaramoorthy, R., Martin, D., Singh, V. & Owen-Hughes, T. 6-Jul-2011 In : EMBO Journal. 30, 13, p. 2596-2609, 14 p.

    Research output: Contribution to journalArticle

  6. The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4

    Gkikopoulos, T., Singh, V., Tsui, K., Awad, S., Renshaw, M. J., Scholfield, P., Barton, G. J., Nislow, C., Tanaka, T. U. & Owen-Hughes, T. 18-May-2011 In : EMBO Journal. 30, 10, p. 1919-1927, 9 p.

    Research output: Contribution to journalArticle

  7. MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases

    Filippi, B. M., de los Heros, P., Mehellou, Y., Navratilova, I., Gourlay, R., Deak, M., Plater, L., Toth, R., Zeqiraj, E. & Alessi, D. R. 4-May-2011 In : EMBO Journal. 30, 9, p. 1730-1741, 12 p.

    Research output: Contribution to journalArticle

  8. AMPK and autophagy get connected

    Hardie, D. G. 16-Feb-2011 In : EMBO Journal. 30, 4, p. 634-635, 2 p.

    Research output: Contribution to journalEditorial

  9. Kinetochore-microtubule interactions: steps towards bi-orientation

    Tanaka, T. U. 15-Dec-2010 In : EMBO Journal. 29, 24, p. 4070-4082, 13 p.

    Research output: Contribution to journalScientific review

  10. RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells

    Piwko, W., Olma, M. H., Held, M., Pedrioli, P. G. A., Gerlich, D. W., Peter, M., Bianco, J. N., Pasero, P. & Hofmann, K. 15-Dec-2010 In : EMBO Journal. 29, 24, p. 4210-4222, 13 p.

    Research output: Contribution to journalArticle

  11. Tyrosine dephosphorylation is required for Bak activation in apoptosis

    Fox, J. L., Ismail, F., Azad, A., Ternette, N., Leverrier, S., Edelmann, M. J., Kessler, B. M., Leigh, I. M., Jackson, S. & Storey, A. 17-Nov-2010 In : EMBO Journal. 29, 22, p. 3853-3868, 16 p.

    Research output: Contribution to journalArticle

  12. IKK and NF-kappa B-mediated regulation of Claspin impacts on ATR checkpoint function

    Kenneth, N. S., Mudie, S. & Rocha, S. 1-Sep-2010 In : EMBO Journal. 29, 17, p. 2966-2978, 13 p.

    Research output: Contribution to journalArticle

  13. S6K1 is a multifaceted regulator of Mdm2 that connects nutrient status and DNA damage response

    Lai, K. P., Leong, W. F., Chau, J. F. L., Jia, D., Zeng, L., Liu, H., He, L., Hao, A., Zhang, H., Meek, D., Velagapudi, C., Habib, S. L. & Li, B. 1-Sep-2010 In : EMBO Journal. 29, 17, p. 2994-3006, 13 p.

    Research output: Contribution to journalArticle

  14. Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor

    Maertens, G. N., El Messaoudi-Aubert, S., Elderkin, S., Hiom, K. & Peters, G. 4-Aug-2010 In : EMBO Journal. 29, 15, p. 2553-2565, 13 p.

    Research output: Contribution to journalArticle

  15. Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest

    Harley, M. E., Allan, L. A., Sanderson, H. S. & Clarke, P. R. 21-Jul-2010 In : EMBO Journal. 29, 14, p. 2407-2420, 14 p.

    Research output: Contribution to journalArticle

  16. Analysis of small RNA in fission yeast; centromeric siRNAs are potentially generated through a structured RNA

    Djupedal, I., Kos-Braun, I. C., Mosher, R. A., Soderholm, N., Simmer, F., Hardcastle, T. J., Fender, A., Heidrich, N., Kagansky, A., Bayne, E., Wagner, E. G. H., Baulcombe, D. C., Allshire, R. C. & Ekwall, K. 16-Dec-2009 In : EMBO Journal. 28, 24, p. 3832-3844, 13 p.

    Research output: Contribution to journalArticle

  17. Cullin neddylation and substrate-adaptors counteract SCF inhibition by the CAND1-like protein Lag2 in Saccharomyces cerevisiae

    Siergiejuk, E., Scott, D. C., Schulman, B. A., Hofmann, K., Kurz, T. & Peter, M. 16-Dec-2009 In : EMBO Journal. 28, 24, p. 3845-3856, 12 p.

    Research output: Contribution to journalArticle

  18. The MRT-1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegans

    Meier, B., Barber, L. J., Liu, Y., Shtessel, L., Boulton, S. J., Gartner, A. & Ahmed, S. 18-Nov-2009 In : EMBO Journal. 28, 22, p. 3549-3563, 15 p.

    Research output: Contribution to journalArticle

  19. Distinct donor and acceptor specificities of Trypanosoma brucei oligosaccharyltransferases

    Izquierdo, L., Schulz, B. L., Rodrigues, J. A., Guther, M. L. S., Procter, J. B., Barton, G. J., Aebi, M. & Ferguson, M. A. J. 2-Sep-2009 In : EMBO Journal. 28, 17, p. 2650-2661, 12 p.

    Research output: Contribution to journalArticle

  20. Gene activation at the edge of the nucleus

    Chubb, J. R. 5-Aug-2009 In : EMBO Journal. 28, 15, p. 2145-2146, 2 p.

    Research output: Contribution to journalComment/debate

  21. Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export-competent RNP

    Topisirovic, I., Siddiqui, N., Lapointe, V. L., Trost, M., Thibault, P., Bangeranye, C., Pinol-Roma, S. & Borden, K. L. B. 22-Apr-2009 In : EMBO Journal. 28, 8, p. 1087-1098, 12 p.

    Research output: Contribution to journalArticle

  22. FACT facilitates chromatin transcription by RNA polymerases I and III

    Birch, J. L., Tan, B. C-M., Panov, K. I., Panova, T. B., Andersen, J. S., Owen-Hughes, T. A., Russell, J., Lee, S-C. & Zomerdijk, J. C. B. M. 8-Apr-2009 In : EMBO Journal. 28, 7, p. 854-865, 12 p.

    Research output: Contribution to journalArticle

  23. TRF2 promotes, remodels and protects telomeric Holliday junctions

    Poulet, A., Buisson, R., Faivre-Moskalenko, C., Koelblen, M., Amiard, S., Montel, F., Cuesta-Lopez, S., Bornet, O., Guerlesquin, F., Godet, T., Moukhtar, J., Argoul, F., Declais, A-C., Lilley, D. M. J., Ip, S. C. Y., West, S. C., Gilson, E. & Giraud-Panis, M-J. 18-Mar-2009 In : EMBO Journal. 28, 6, p. 641-651, 11 p.

    Research output: Contribution to journalArticle

  24. Structural insights into mechanism and specificity of O-GlcNAc transferase

    Clarke, A. J., Hurtado-Guerrero, R., Pathak, S., Schuettelkopf, A., Borodkin, V., Shepherd, S. M., Ibrahim, A. F. M. & van Aalten, D. M. F. 22-Oct-2008 In : EMBO Journal. 27, 20, p. 2780-2788, 9 p.

    Research output: Contribution to journalArticle

  25. The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development

    Kulathu, Y., Hobeika, E., Turchinovich, G. & Reth, M. 7-May-2008 In : EMBO Journal. 27, 9, p. 1333-44, 12 p.

    Research output: Contribution to journalArticle

  26. Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

    Hamilton, G., Colbert, J. D., Schuettelkopf, A. W. & Watts, C. 6-Feb-2008 In : EMBO Journal. 27, 3, p. 499-508, 10 p.

    Research output: Contribution to journalArticle

  27. Cajal bodies and the nucleolus are required for a plant virus systemic infection

    Kim, S. H., Ryabov, E. V., Kalinina, N. O., Rakitina, D. V., Gillespie, T., MacFarlane, S., Haupt, S., Brown, J. W. S. & Taliansky, M. Apr-2007 In : The EMBO Journal. 26, 8, p. 2169-2179, 11 p.

    Research output: Contribution to journalArticle

  28. A novel TBP-associated factor of SL1 functions in RNA polymerase I transcription

    Gorski, J. J., Pathak, S., Panov, K., Kasciukovic, T., Panova, T., Russell, J. & Zomerdijk, J. C. B. M. Mar-2007 In : The EMBO Journal. 26, 6, p. 1560-1568, 9 p.

    Research output: Contribution to journalArticle

  29. A cell cycle regulatory network controlling NF-B subunit activity and function

    Barre, B. & Perkins, N. 2007 In : The EMBO Journal. 26, 23, p. 4841-4855, 15 p.

    Research output: Contribution to journalArticle

  30. The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2

    Stevenson, L. F., Sparks, A., Allende-Vega, N., Xirodimas, D. P., Lane, D. & Saville, M. K. 2007 In : The EMBO Journal. 26, 4, p. 976-986, 11 p.

    Research output: Contribution to journalArticle

  31. Regulation of p53 tumour suppressor target gene expression by the p52 NF-kappaB subunit

    Schumm, K., Rocha, S., Caamano, J. & Perkins, N. D. Oct-2006 In : The EMBO Journal. 25, 20, p. 4820-4832, 13 p.

    Research output: Contribution to journalArticle

  32. A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic β-cells

    Ning, K., Miller, L. C., Laidlaw, H. A., Burgess, L. A., Perera, N. M., Downes, C. P., Leslie, N. R. & Ashford, M. L. J. Jun-2006 In : The EMBO Journal. 25, 11, p. 2377-2387, 11 p.

    Research output: Contribution to journalArticle

  33. Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysis

    Rao, F. V., Dorfmueller, H. C., Villa, F., Allwood, M., Eggleston, I. M. & van Aalten, D. M. F. 2006 In : The EMBO Journal. 25, 7, p. 1569-1578, 10 p.

    Research output: Contribution to journalArticle

  34. UBF activates RNA polymerase I transcription by stimulating promoter escape

    Panov, K. I., Friedrich, J. K., Russell, J. & Zomerdijk, J. C. B. M. 2006 In : The EMBO Journal. 25, 14, p. 3310-3322, 13 p.

    Research output: Contribution to journalArticle

  35. Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction

    Sakamoto, K., McCarthy, A., Smith, D., Green, K. A., Hardie, D. G., Ashworth, A. & Alessi, D. R. May-2005 In : The EMBO Journal. 24, 10, p. 1810-1820, 11 p.

    Research output: Contribution to journalArticle

  36. The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells

    Cartlidge, R. A., Knebel, A., Peggie, M., Alexandrov, A., Phizicky, E. M. & Cohen, P. May-2005 In : The EMBO Journal. 24, 9, p. 1696-1705, 10 p.

    Research output: Contribution to journalArticle

  37. Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis

    McManus, E. J., Sakamoto, K., Armit, L. J., Ronaldson, L., Shpiro, N., Marquez, R. & Alessi, D. R. Apr-2005 In : The EMBO Journal. 24, 8, p. 1571-1583, 13 p.

    Research output: Contribution to journalArticle

  38. Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1

    Shen, L., Liu, H., Dong, C., Xirodimas, D., Naismith, J. H. & Hay, R. T. Apr-2005 In : The EMBO Journal. 24, 7, p. 1341-1351, 11 p.

    Research output: Contribution to journalArticle

  39. Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor

    Rocha, S., Garrett, M. D., Campbell, K. J., Schumm, K. & Perkins, N. D. Mar-2005 In : EMBO Journal. 24, 6, p. 1157-1169, 13 p.

    Research output: Contribution to journalArticle

  40. The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor

    Bates, G. J., Nicol, S. M., Wilson, B. J., Jacobs, A-M. F., Bourdon, J-C., Wardrop, J., Gregory, D. J., Lane, D. P., Perkins, N. D. & Fuller-Pace, F. V. 9-Feb-2005 In : The EMBO Journal. 24, 3, p. 543-553, 11 p.

    Research output: Contribution to journalArticle

  41. Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus

    Li, A. & Blow, J. J. Jan-2005 In : The EMBO Journal. 24, 2, p. 395-404, 10 p.

    Research output: Contribution to journalArticle

  42. Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway

    Seternes, O-M., Mikalsen, T., Johansen, B., Michaelsen, E., Armstrong, C. G., Morrice, N. A., Turgeon, B., Meloche, S., Moens, U. & Keyse, S. M. Dec-2004 In : The EMBO Journal. 23, 24, p. 4780-4791, 12 p.

    Research output: Contribution to journalArticle

  43. Chemical validation of GPI biosynthesis as a drug target against African sleeping sickness

    Smith, T. K., Crossman, A., Brimacombe, J. S. & Ferguson, M. A. J. Nov-2004 In : The EMBO Journal. 23, 23, p. 4701-4708, 8 p.

    Research output: Contribution to journalArticle

  44. LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

    Lizcano, J. M., Goransson, O., Toth, R., Deak, M., Morrice, N. A., Boudeau, J., Hawley, S., Udd, L., Makela, T. P., Hardie, D. G. & Alessi, D. R. Feb-2004 In : The EMBO Journal. 23, 4, p. 833-843, 11 p.

    Research output: Contribution to journalArticle

  45. Coordinating assembly and export of complex bacterial proteins

    Jack, R. L., Buchanan, G., Dubini, A., Hatzixanthis, K., Palmer, T. & Sargent, F. 2004 In : The EMBO Journal. 23, 20, p. 3962-3972, 11 p.

    Research output: Contribution to journalArticle

  46. Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage

    Rouse, J. 2004 In : The EMBO Journal. 23, 5, p. 1188-1197, 10 p.

    Research output: Contribution to journalArticle

  47. Sin mutations alter inherent nucleosome mobility

    Flaus, A., Rencurel, C., Ferreira, H., Wiechens, N. & Owen-Hughes, T. 2004 In : The EMBO Journal. 23, 2, p. 343-353, 11 p.

    Research output: Contribution to journalArticle

  48. Redox regulation of PI 3-kinase signalling via inactivation of PTEN

    Leslie, N., Bennett, D., Downes, P., Gray, A., Lindsay, Y. E. & Stewart, H. Oct-2003 In : EMBO Journal. 22, 20, p. 5501-5510, 10 p.

    Research output: Contribution to journalArticle

  49. Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

    Mora, A., Davies, A. M., Bertrand, L., Sharif, I., Budas, G. R., Jovanovic, S., Mouton, V., Kahn, C. R., Lucocq, J. M., Gray, G. A., Jovanovic, A. & Alessi, D. R. Sep-2003 In : The EMBO Journal. 22, 18, p. 4666-4676, 11 p.

    Research output: Contribution to journalArticle

  50. Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways

    Gatfield, D., Unterholzner, L., Ciccarelli, F. D., Bork, P. & Izaurralde, E. 1-Aug-2003 In : EMBO Journal. 22, 15, p. 3960-70, 11 p.

    Research output: Contribution to journalArticle

  51. 14-3-3s regulate fructose-2,6-bisphosphate levels by binding to PKB-phosphorylated cardiac fructose-2,6-bisphosphate kinase/phosphatase

    Pozuelo-Rubio, M., Peggie, M., Wong, B. H. C., Morrice, N. & MacKintosh, C. 15-Jul-2003 In : The EMBO Journal. 22, 14, p. 3514-3523, 10 p.

    Research output: Contribution to journalArticle

  52. MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14

    Soloaga, A., Thomson, S., Wiggin, G. R., Rampersaud, N., Dyson, M. H., Hazzalin, C. A., Mahadevan, L. C. & Arthur, J. S. C. Jun-2003 In : The EMBO Journal. 22, 11, p. 2788-2797, 10 p.

    Research output: Contribution to journalArticle

  53. Autoregulation of FCA pre-mRNA processing controls Arabidopsis flowering time

    Quesada, V., Macknight, R., Dean, C. & Simpson, G. G. Jan-2003 In : The EMBO Journal. 22, 12, p. 3142-3152, 11 p.

    Research output: Contribution to journalArticle

  54. Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD

    Baas, A. F., Boudeau, J., Sapkota, G. P., Smit, L., Medema, R., Morrice, N. A., Alessi, D. R. & Clevers, H. C. 2003 In : EMBO Journal. 22, 12, p. 3062-3072, 11 p.

    Research output: Contribution to journalArticle

  55. Feedback control of the protein kinase TAK1 by SAPK2a/p38

    Cheung, P. C. F., Campbell, D. G., Nebreda, A. R. & Cohen, P. 2003 In : The EMBO Journal. 22, 21, p. 5793-5805, 13 p.

    Research output: Contribution to journalArticle

  56. Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs

    Rousseau, S., Morrice, N., Peggie, M., Campbell, D. G., Gaestel, M. & Cohen, P. Dec-2002 In : The EMBO Journal. 21, 23, p. 6505-6514, 10 p.

    Research output: Contribution to journalArticle

  57. Altered aggregation properties of mutant γ-crystallins cause inherited cataract

    Sandilands, A., Hutcheson, A. M., Long, H. A., Prescott, A. R., Vrensen, G., Loster, J., Klopp, N., Lutz, R. B., Graw, J., Masaki, S., Dobson, C. M., MacPhee, C. E. & Quinlan, R. A. Nov-2002 In : The EMBO Journal. 21, 22, p. 6005-6014, 10 p.

    Research output: Contribution to journalArticle

  58. Different Smad2 partners bind a common hydrophobic pocket in Smad2 via a defined proline-rich motif

    Randall, R. A., Germain, S., Inman, G. J., Bates, P. A. & Hill, C. S. 2002 In : EMBO Journal. 21, 1-2, p. 145-156, 12 p.

    Research output: Contribution to journalArticle

  59. Four new subunits of the Dam1-Duo1 complex reveal novel functions in sister kinetochore biorientation

    Janke, C., Ortíz, J., Tanaka, T. U., Lechner, J. & Schiebel, E. 2002 In : EMBO Journal. 21, 1-2, p. 181-93, 13 p.

    Research output: Contribution to journalArticle

  60. Metal ions bound at the active site of the junction-resolving enzyme T7 endonuclease I

    Hadden, J. M., Declais, A-C., Phillips, S. E. V. & Lilley, D. M. J. 2002 In : The EMBO Journal. 21, 13, p. 3505-3515, 11 p.

    Research output: Contribution to journalArticle

  61. The global structure of the VS ribozyme

    Lafontaine, D. A., Norman, D. G. & Lilley, D. M. J. 2002 In : EMBO Journal. 21, 10, p. 2461-2471, 11 p.

    Research output: Contribution to journalArticle

  62. Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

    Rena, G., Woods, Y. L., Prescott, A. R., Peggie, M., Unterman, T. G., Williams, M. R. & Cohen, P. 2002 In : The EMBO Journal. 21, 9, p. 2263-2271, 9 p.

    Research output: Contribution to journalArticle

  63. A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38

    Knebel, A., Morrice, N. & Cohen, P. Aug-2001 In : The EMBO Journal. 20, 16, p. 4360-4369, 10 p.

    Research output: Contribution to journalArticle

  64. Specificity of GlcNAc-Pl de-N-acetylase of GPI biosynthesis and synthesis of parasite-specific suicide substrate inhibitors

    Smith, T. K., Crossman, A., Borissow, C. N., Paterson, M. J., Dix, A., Brimacombe, J. S. & Ferguson, M. A. J. 2-Jul-2001 In : EMBO Journal. 20, 13, p. 3322-3332, 11 p.

    Research output: Contribution to journalArticle

  65. Human acrocentric chromosomes with transcriptionally silent nucleolar organizer regions associate with nucleoli

    Sullivan, G. J., Bridger, J. M., Cuthbert, A. P., Newbold, R. F., Bickmore, W. A. & McStay, B. Jun-2001 In : The EMBO Journal. 20, 11, p. 2867-2877, 11 p.

    Research output: Contribution to journalArticle

  66. hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters

    Miller, G., Panov, K. I., Friedrich, J. K., Trinkle-Mulcahy, L., Lamond, A. I. & Zomerdijk, J. C. B. M. Mar-2001 In : The EMBO Journal. 20, 6, p. 1373-1382, 10 p.

    Research output: Contribution to journalArticle

  67. Control of chromosomal DNA replication in the early Xenopus embryo

    Blow, J. J. 2001 In : EMBO Journal. 20, 13, p. 3293-3297, 5 p.

    Research output: Contribution to journalArticle

  68. Modes of spindle pole body inheritance and segregation of the Bfa1p-Bub2p checkpoint protein complex

    Pereira, G., Tanaka, T. U., Nasmyth, K. & Schiebel, E. 2001 In : EMBO Journal. 20, 22, p. 6359-70, 12 p.

    Research output: Contribution to journalArticle

  69. Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1

    Holmberg, C. I., Hietakangas, V., Mikhailov, A., Rantanen, J. O., Kallio, M., Meinander, A., Hellman, J., Morrice, N., MacKintosh, C., Morimoto, R. I., Eriksson, J. E. & Sistonen, L. 2001 In : EMBO Journal. 20, 14, p. 3800-3810, 11 p.

    Research output: Contribution to journalArticle

  70. Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei

    Güther, M. L. S., Leal, S., Morrice, N. A., Cross, G. A. M. & Ferguson, M. A. J. 2001 In : The EMBO Journal. 20, 17, p. 4923-4934, 12 p.

    Research output: Contribution to journalArticle

  71. Structure, folding and activity of the VS ribozyme: importance of the 2-3-6 helical junction

    Lafontaine, D. A., Norman, D. G. & Lilley, D. M. J. 2001 In : The EMBO Journal. 20, 6, p. 1415-1424, 10 p.

    Research output: Contribution to journalArticle

  72. Highly purified glycosylphosphatidylinositols from Trypanosoma cruzi are potent proinflammatory agents

    Almeida, I. C., Camargo, M. M., Procopio, D. O., Silva, L. S., Mehlert, A., Travassos, L. R., Gazzinelli, R. T. & Ferguson, M. A. J. 3-Apr-2000 In : EMBO Journal. 19, 7, p. 1476-1485, 10 p.

    Research output: Contribution to journalArticle

  73. 14-3-3s regulate global cleavage of their diverse binding partners in sugar-starved Arabidopsis cells

    Cotelle, V., Meek, S. E. M., Provan, F., Milne, F. C., Morrice, N. & MacKintosh, C. 2000 In : EMBO Journal. 19, 12, p. 2869-2876, 8 p.

    Research output: Contribution to journalArticle

  74. Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry

    Ajuh, P., Kuster, B., Panov, K., Zomerdijk, J. C. B. M., Mann, M. & Lamond, A. I. 2000 In : EMBO Journal. 19, 23, p. 6569-6581, 13 p.

    Research output: Contribution to journalArticle

  75. Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins

    Nijtmans, L. G. J., de Jong, L., Artal Sanz, M., Coates, P. J., Berden, J. A., Back, J. W., Muijsers, A. O., van der Spek, H. & Grivell, L. A. 2000 In : EMBO Journal. 19, 11, p. 2444-2451, 8 p.

    Research output: Contribution to journalArticle

  76. Promiscuous targeting of Bacillus subtilis cell division protein DivIVA to division sites in Escherichia coli and fission yeast

    Edwards, D. H., Thomaides, H. B. & Errington, J. 2000 In : EMBO Journal. 19, 11, p. 2719-2727, 9 p.

    Research output: Contribution to journalArticle

  77. Spatial and temporal regulation of protein kinase D (PKD)

    Matthews, S. A., Iglesias, T., Rozengurt, E. & Cantrell, D. 2000 In : EMBO Journal. 19, 12, p. 2935-45, 11 p.

    Research output: Contribution to journalArticle

  78. Serine 15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2

    Dumaz, N. & Meek, D. W. 15-Dec-1999 In : EMBO Journal. 18, 24, p. 7002-7010, 9 p.

    Research output: Contribution to journalArticle

  79. Selective inhibitors of the glycosylphosphatidylinositol biosynthetic pathway of Trypanosoma brucei

    Smith, T. K., Sharma, D. K., Crossman, A., Brimacombe, J. S. & Ferguson, M. A. J. 1-Nov-1999 In : EMBO Journal. 18, 21, p. 5922-5930, 9 p.

    Research output: Contribution to journalArticle

  80. Regulation of JNK signaling by GSTp

    Adler, V., Yin, Z., Fuchs, S. Y., Benezra, M., Rosario, L., Tew, K. D., Pincus, M. R., Sardana, M., Henderson, C. J., Wolf, C. R., Davis, R. J. & Ronai, Z. 1-Mar-1999 In : EMBO Journal. 18, 5, p. 1321-1334, 14 p.

    Research output: Contribution to journalArticle

  81. Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry

    Brunet, A., Roux, D., Lenormand, P., Dowd, S., Keyse, S. & Pouysségur, J. 1-Feb-1999 In : EMBO Journal. 18, 3, p. 664-74, 11 p.

    Research output: Contribution to journalArticle

  82. Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage

    Alexandru, G., Zachariae, W., Schleiffer, A. & Nasmyth, K. 1999 In : EMBO Journal. 18, 10, p. 2707-2721, 15 p.

    Research output: Contribution to journalArticle

  83. Overlapping functions of components of a bacterial Sec-independent protein export pathway

    Sargent, F., Bogsch, E. G., Stanley, N. R., Wexler, M., Robinson, C., Berks, B. C. & Palmer, T. 1998 In : EMBO Journal. 17, 13, p. 3640-3650, 11 p.

    Research output: Contribution to journalArticle

  84. The RLF-M component of the replication licensing system forms complexes containing all six MCM/P1 polypeptides

    Thömmes, P., Kubota, Y., Takisawa, H. & Blow, J. J. 1-Jun-1997 In : EMBO Journal. 16, 11, p. 3312-3319, 8 p.

    Research output: Contribution to journalArticle

  85. Parasite and mammalian GPI biosynthetic pathways can be distinguished using synthetic substrate analogues

    Smith, T. K., Sharma, D. K., Crossman, A., Dix, A., Brimacombe, J. S. & Ferguson, M. A. J. 1997 In : EMBO Journal. 16, 22, p. 6667-6675, 9 p.

    Research output: Contribution to journalArticle

  86. Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase

    Groom, L. A., Sneddon, A. A., Alessi, D. R., Dowd, S. & Keyse, S. M. 1996 In : EMBO Journal. 15, 14, p. 3621-32, 12 p.

    Research output: Contribution to journalArticle

  87. DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective

    Allday, M. J., Inman, G. J., Crawford, D. H. & Farrell, P. J. 16-Oct-1995 In : EMBO Journal. 14, 20, p. 4994-5005, 12 p.

    Research output: Contribution to journalArticle

  88. The role of inositol acylation and inositol deacylation in GPI biosynthesis in Trypanosoma brucei

    Guther, M. L. S. & Ferguson, M. A. J. 1-Jan-1995 In : EMBO Journal. 14, 13, p. 3080-3093, 14 p.

    Research output: Contribution to journalArticle

  89. Interaction with calmodulin is required for the function of Spc110p, an essential component of the yeast spindle pole body

    Stirling, D. A., Welch, K. A. & Stark, M. J. R. 1994 In : EMBO Journal. 13, 18, p. 4329-4342, 14 p.

    Research output: Contribution to journalArticle

  90. Developmental modification of lipophosphoglycan during the differentiation of Leishmania major promastigotes to an infectious stage.

    McConville, M. J., Turco, S. J., Ferguson, M. A. J. & Sacks, D. L. Oct-1992 In : EMBO Journal. 11, 10, p. 3593-3600, 8 p.

    Research output: Contribution to journalArticle

  91. Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates

    Norbury, C., Blow, J. & Nurse, P. Nov-1991 In : EMBO Journal. 10, 11, p. 3321-9, 9 p.

    Research output: Contribution to journalArticle

  92. Phenylmethanesulphonyl fluoride inhibits GPI anchor biosynthesis in the African trypanosome

    Masterson, W. J. & Ferguson, M. A. J. Aug-1991 In : EMBO Journal. 10, 8, p. 2041-2045, 5 p.

    Research output: Contribution to journalArticle

  93. Saccharomyces cerevisiae protein phosphatase 2A performs an essential cellular function and is encoded by two genes

    Sneddon, A. A., Cohen, P. T. W. & Stark, M. J. R. Dec-1990 In : EMBO Journal. 9, 13, p. 4339-4346, 8 p.

    Research output: Contribution to journalArticle

  94. The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II

    Meek, D. W., Simon, S., Kikkawa, U. & Eckhart, W. 1990 In : EMBO Journal. 9, 10, p. 3253-3260, 8 p.

    Research output: Contribution to journalArticle

  95. The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei

    Zomerdijk, J. C. B. M., Ouellette, M., ten Asbroek, A. L. M. A., Kieft, R., Bommer, A. M. M., Clayton, C. E. & Borst, P. 1990 In : EMBO Journal. 9, 9, p. 2791-2801, 11 p.

    Research output: Contribution to journalArticle

  96. Isolation and structural analysis of a peptide containing the novel tyrosyl-glucose linkage in glycogenin.

    Smythe, C., Caudwell, F. B., Ferguson, M. A. J. & Cohen, P. 7-Sep-1988 In : EMBO Journal. 7, 9, p. 2681-2686, 6 p.

    Research output: Contribution to journalArticle

  97. Nuclei act as independent and integrated units of replication in a Xenopus cell-free DNA replication system

    Blow, J. J. & Watson, J. V. Jul-1987 In : EMBO Journal. 6, 7, p. 1997-2002, 6 p.

    Research output: Contribution to journalArticle

  98. In vivo labelling of intermediates in the discontinuous synthesis of mRNAs in Trypanosoma brucei

    Laird, P. W., Zomerdijk, J. C. B. M., de Korte, D. & Borst, P. 1987 In : EMBO Journal. 6, 4, p. 1055-1062, 8 p.

    Research output: Contribution to journalArticle

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