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EMBO Journal

  1. The hVPS34-SGK3 pathway counteracts inhibition of the PI3K-Akt to maintain mTORC1 and tumour growth

    Bago, R., Eskelinen, E-L., Castel , P., Crafter, C., Bailey, F. P., Shpiro, N., Baselga, J., Cross, D., Eyers, P. & Alessi, D. 15 Aug 2016 In : EMBO Journal. 35, 16, p. 1721-1843 33 p., e201693929

    Research output: Contribution to journalArticle

  2. Phosphopeptide binding by Sld3 links Dbf4-dependent kinase to MCM replicative helicase activation

    Deegan, T. D., Yeeles, J. T. P. & Diffley, J. F. X. 2016 In : EMBO Journal. 35

    Research output: Contribution to journalArticle

  3. Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis

    Kumar, A., Aguirre, J. D., Condos, T. E. C., Martinez-Torres, R. J., Chaugule, V. K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D. E., Barber, K. R., Shaw, G. S. & Walden, H. 14 Oct 2015 In : EMBO Journal. 34, 20, p. 2506-2521 16 p.

    Research output: Contribution to journalArticle

  4. mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival

    Munson, M. J., Allen, G. F. G., Toth, R., Campbell, D. G., Lucocq, J. M. & Ganley, I. G. 2 Sep 2015 In : EMBO Journal. 34, 17, p. 2272-2290 19 p.

    Research output: Contribution to journalArticle

  5. Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes

    Preston, G. C., Sinclair, L. V., Kaskar, A., Hukelmann, J. L., Navarro, M., Ferrero, I., MacDonald, H. R., Cowling, V. H. & Cantrell, D. A. 4 Aug 2015 In : EMBO Journal. 34, 15, p. 2008-2024 17 p.

    Research output: Contribution to journalArticle

  6. USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses

    Perez-Oliva, A. B., Lachaud, C., Szyniarowski, P., Muñoz, I., Macartney, T., Hickson, I., Rouse, J. & Alessi, D. R. 3 Feb 2015 In : EMBO Journal. 34, 3, p. 326-343 18 p.

    Research output: Contribution to journalArticle

  7. Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1

    Lai, Y-C., Kondapalli, C., Lehneck, R., Procter, J. B., Dill, B. D., Woodroof, H. I., Gourlay, R., Peggie, M., Macartney, T. J., Corti, O., Corvol, J-C., Campbell, D. G., Itzen, A., Trost, M. & Muqit, M. M. K. 2015 In : EMBO Journal. 22 p.

    Research output: Contribution to journalArticle

  8. A cyclic GMP-dependent signalling pathway regulates bacterial phytopathogenesis

    An, S-Q., Chin, K-H., Febrer, M., McCarthy, Y., Yang, J-G., Liu, C-L., Swarbreck, D., Rogers, J., Dow, J. M., Chou, S-H. & Ryan, R. P. 11 Sep 2013 In : EMBO Journal. 32, 18, p. 2430-2438

    Research output: Contribution to journalArticle

  9. Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease

    Sharifi, R. , Morra, R. , Appel, C. D. , Tallis, M. , Chioza, B. , Jankevicius, G. , Simpson, M. A. , Matic, I. , Ozkan, E. , Golia, B. , Schellenberg, M. J. , Weston, R. , Williams, J. G. , Rossi, M. N. , Galehdari, H. , Krahn, J. , Wan, A. , Trembath, R. C. , Crosby, A. H. & 6 others Ahel, D., Hay, R., Ladurner, A. G., Timinszky, G., Williams, R. S. & Ahel, I. 2 May 2013 In : EMBO Journal. 32, 9, p. 1225-1237 13 p.

    Research output: Contribution to journalArticle

  10. PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development

    Venigalla, R. K. C., McGuire, V. A., Clarke, R., Patterson-Kane, J. C., Najafov, A., Toth, R., McCarthy, P. C., Simeons, F., Stojanovski, L. & Arthur, J. S. C. 3 Apr 2013 In : EMBO Journal. 32, 7, p. 1008-22 15 p.

    Research output: Contribution to journalArticle

  11. A sweet TET-a-tete-synergy of TET proteins and O-GlcNAc transferase in transcription

    Mariappa, D., Pathak, S. & van Aalten, D. M. F. 2013 In : EMBO Journal. 32, 5, p. 612-613 2 p.

    Research output: Contribution to journalEditorial

  12. TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes

    Kelsall, I. R., Duda, D. M., Olszewski, J. L., Hofmann, K., Knebel, A., Langevin, F., Wood, N., Wightman, M., Schulman, B. A. & Alpi, A. F. 2013 In : EMBO Journal. 32, p. 2848-2860 13 p.

    Research output: Contribution to journalArticle

  13. The Mitotic Exit Network and Cdc14 phosphatase initiate cytokinesis by counteracting CDK phosphorylations and blocking polarised growth

    Sanchez-Diaz, A., Nkosi, P. J., Murray, S. & Labib, K. 29 Aug 2012 In : EMBO Journal. 31, 17, p. 3620-3634 15 p.

    Research output: Contribution to journalArticle

  14. Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation

    van Deursen, F., Sengupta, S., De Piccoli, G., Sanchez-Diaz, A. & Labib, K. 2 May 2012 In : EMBO Journal. 31, 9, p. 2195-2206 12 p.

    Research output: Contribution to journalArticle

  15. Sperm are promiscuous and CatSper is to blame...

    Barratt, C. L. R. & Publicover, S. J. 4 Apr 2012 In : EMBO Journal. 31, 7, p. 1624-1626 3 p.

    Research output: Contribution to journalArticle

  16. O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release

    Pathak, S., Borodkin, V. S., Albarbarawi, O., Campbell, D. G., Ibrahim, A. & van Aalten, D. M. F. 21 Mar 2012 In : EMBO Journal. 31, 6, p. 1394-1404 11 p.

    Research output: Contribution to journalArticle

  17. Building a double hexamer of DNA helicase at eukaryotic replication origins

    Labib, K. 14 Dec 2011 In : EMBO Journal. 30, 24, p. 4853-4855 3 p.

    Research output: Contribution to journalArticle

  18. Autoregulation of Parkin activity through its ubiquitin-like domain

    Chaugule, V. K., Burchell, L., Barber, K. R., Sidhu, A., Leslie, S. J., Shaw, G. S. & Walden, H. 20 Jul 2011 In : EMBO Journal. 30, 14, p. 2853-2867 15 p.

    Research output: Contribution to journalArticle

  19. The DNA-binding domain of the Chd1 chromatin-remodelling enzyme contains SANT and SLIDE domains

    Ryan, D. P., Sundaramoorthy, R., Martin, D., Singh, V. & Owen-Hughes, T. 6 Jul 2011 In : EMBO Journal. 30, 13, p. 2596-2609 14 p.

    Research output: Contribution to journalArticle

  20. The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4

    Gkikopoulos, T., Singh, V., Tsui, K., Awad, S., Renshaw, M. J., Scholfield, P., Barton, G. J., Nislow, C., Tanaka, T. U. & Owen-Hughes, T. 18 May 2011 In : EMBO Journal. 30, 10, p. 1919-1927 9 p.

    Research output: Contribution to journalArticle

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