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  1. A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

    Wypijewski, K. J., Howie, J., Reilly, L., Tulloch, L. B., Aughton, K. L., McLatchie, L. M., Shattock, M. J., Calaghan, S. C. & Fuller, W. 2013 In : Journal of Biological Chemistry.

    Research output: Contribution to journal › Article

  2. Ca2+ signalling through CatSper and Ca2+ stores regulate different behaviours in human sperm

    Alasmari, W., Costello, S., Correia, J., Oxenham, S. K., Morris, J., Fernandes, L., Ramalho Santos, J., Kirkman-Brown, J., Michelangeli, F., Publicover, S. & Barratt, C. L. R. 2013 In : Journal of Biological Chemistry.

    Research output: Contribution to journal › Article

  3. Dual regulation of Glycogen Synthase Kinase 3 (GSK3)alpha/beta by Protein Kinase C (PKC)alpha and Akt promotes Thrombin-mediated Integrin alpha(IIb)beta(3) activation and granule secretion in platelets

    Moore, S. F., van den Bosch, M. T. J., Hunter, R. W., Sakamoto, K., Poole, A. W. & Hers, I. 2013 In : Journal of Biological Chemistry. 288, 6, p. 3918-3928, 11 p.

    Research output: Contribution to journal › Article

  4. The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow

    Lek, H. S., Morrison, V. L., Conneely, M., Campbell, P. A., McGloin, D., Kliche, S., Watts, C., Prescott, A. & Fagerholm, S. C. 2013 In : Journal of Biological Chemistry.

    Research output: Contribution to journal › Article

  5. Family with Sequence Similarity 60A (FAM60A) Protein Is a Cell Cycle-fluctuating Regulator of the SIN3-HDAC1 Histone Deacetylase Complex

    Munoz, I. M., Macartney, T., Sanchez-Pulido, L., Ponting, C. P., Rocha, S. & Rouse, J. 21-Sep-2012 In : Journal of Biological Chemistry. 287, 39, p. 32346-53, 8 p.

    Research output: Contribution to journal › Article

  6. Monoubiquitination Promotes Calpain Cleavage of the Protein Phosphatase 2A (PP2A) Regulatory Subunit alpha 4, Altering PP2A Stability and Microtubule-associated Protein Phosphorylation

    Watkins, G. R., Wang, N., Mazalouskas, M. D., Gomez, R. J., Guthrie, C. R., Kraemer, B. C., Schweiger, S., Spiller, B. W. & Wadzinski, B. E. 13-Jul-2012 In : Journal of Biological Chemistry. 287, 29, p. 24207-24215, 9 p.

    Research output: Contribution to journal › Article

  7. IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold

    Dixon, M. J., Gray, A., Schenning, M., Agacan, M., Tempel, W., Tong, Y., Nedyalkova, L., Park, H-W., Leslie, N. R., van Aalten, D. M. F., Downes, C. P. & Batty, I. H. 29-Jun-2012 In : Journal of Biological Chemistry. 287, 27, p. 22483-22496, 14 p.

    Research output: Contribution to journal › Article

  8. Defining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cells

    Turban, S., Stretton, C., Drouin, O., Green, C. J., Watson, M. L., Gray, A., Ross, F., Lantier, L., Viollet, B., Hardie, D. G., Hundal, H. S. & Marette, A. 8-Jun-2012 In : Journal of Biological Chemistry. 287, 24, p. 20088-20099, 12 p.

    Research output: Contribution to journal › Article

  9. Essential Role for IKK beta in Production of Type 1 Interferons by Plasmacytoid Dendritic Cells

    Pauls, E., Shpiro, N., Peggie, M., Young, E. R., Sorcek, R. J., Tan, L., Choi, H. G. & Cohen, P. 1-Jun-2012 In : Journal of Biological Chemistry. 287, 23, p. 19216-19228, 13 p.

    Research output: Contribution to journal › Article

  10. Escherichia coli TatA and TatB Proteins Have N-out, C-in Topology in Intact Cells

    Koch, S., Fritsch, M. J., Buchanan, G. & Palmer, T. 27-Apr-2012 In : Journal of Biological Chemistry. 287, 18, p. 14420-14431, 12 p.

    Research output: Contribution to journal › Article

  11. Distinct control of MyD88 adapter-dependent and Akt kinase-regulated responses by the interleukin (IL)-1RI co-receptor, TILRR

    Zhang, X., Montagut Pino, G., Shephard, F., Kiss-Toth, E. & Qwarnstrom, E. E. 6-Apr-2012 In : Journal of Biological Chemistry. 287, 15, p. 12348-12352, 5 p.

    Research output: Contribution to journal › Article

  12. Phosphorylation of FOXO3a on Ser-7 by p38 promotes its nuclear localization in response to doxorubicin

    Ho, K-K., McGuire, V. A., Koo, C-Y., Muir, K. W., de Olano, N., Maifoshie, E., Kelly, D. J., McGovern, U. B., Monteiro, L. J., Gomes, A. R., Nebreda, A. R., Campbell, D. G., Arthur, J. S. C. & Lam, E. W. -F. 6-Jan-2012 In : Journal of Biological Chemistry. 287, 2, p. 1545-1555, 11 p.

    Research output: Contribution to journal › Article

  13. Modulation of L-alpha-Lysophosphatidylinositol/GPR55 Mitogen-activated Protein Kinase (MAPK) Signaling by Cannabinoids

    Anavi-Goffer, S., Baillie, G., Irving, A. J., Gertsch, J., Greig, I. R., Pertwee, R. G. & Ross, R. A. 2-Jan-2012 In : Journal of Biological Chemistry. 287, 1, p. 91-104, 14 p.

    Research output: Contribution to journal › Article

  14. Avirulence protein 3a (AVR3a) from the potato pathogen Phytophthora infestans forms homodimers through its predicted translocation region and does not specifically bind phospholipids

    Wawra, S., Agacan, M., Boddey, J. A., Davidson, I., Gachon, C. M. M., Zanda, M., Grouffaud, S., Whisson, S. C., Birch, P. R. J., Porter, A. J. & Van West, P. 2012 In : Journal of Biological Chemistry. 287, 45, p. 38101-38109, 9 p.

    Research output: Contribution to journal › Article

  15. Pellino1 Is Required for Interferon Production by Viral Double-stranded RNA

    Enesa, K., Ordureau, A., Smith, H., Barford, D., Cheung, P. C. F., Patterson-Kane, J., Arthur, J. S. C. & Cohen, P. 2012 In : Journal of Biological Chemistry. 287, 41, p. 34825-34835, 11 p.

    Research output: Contribution to journal › Article

  16. Role of binding and nucleoside diphosphate kinase A in the regulation of the cystic fibrosis transmembrane conductance regulator by AMP-activated protein kinase

    King, J. D., Lee, J., Riemen, C. E., Neumann, D., Xiong, S., Foskett, J. K., Mehta, A., Muimo, R. & Hallows, K. R. 2012 In : Journal of Biological Chemistry. 287, 40, p. 33389-33400, 12 p.

    Research output: Contribution to journal › Article

  17. Transforming Growth Factor-β directly induces PUMA during the rapid induction of apoptosis in Myc-driven B-cell lymphomas.

    Spender, L. C., Carter, M. J., O'Brien, D. I., Clark, L. J., Yu, J., Michalak, E. M., Happo, L., Cragg, M. S. & Inman, G. J. 2012 In : Journal of Biological Chemistry.

    Research output: Contribution to journal › Article

  18. Distinct Docking Mechanisms Mediate Interactions between the Msg5 Phosphatase and Mating or Cell Integrity Mitogen-activated Protein Kinases (MAPKs) in Saccharomyces cerevisiae

    Palacios, L., Dickinson, R. J., Sacristan-Reviriego, A., Didmon, M. P., Jose Marin, M., Martin, H., Keyse, S. M. & Molina, M. 9-Dec-2011 In : Journal of Biological Chemistry. 286, 49, p. 42037-42050, 14 p.

    Research output: Contribution to journal › Article

  19. Internalization of Exogenous Cystatin F Supresses Cysteine Proteases and Induces the Accumulation of Single-chain Cathepsin L by Multiple Mechanisms

    Colbert, J. D., Matthews, S. P., Kos, J. & Watts, C. 9-Dec-2011 In : Journal of Biological Chemistry. 286, 49, p. 42082-42090, 9 p.

    Research output: Contribution to journal › Article

  20. Chemical structure of Trichomonas vaginalis surface lipoglycan: a role for short galactose (beta 1-4/3) N-acetylglucosamine repeats in host cell interaction

    Ryan, C. M., Mehlert, A., Richardson, J. M., Ferguson, M. A. J. & Johnson, P. J. 25-Nov-2011 In : Journal of Biological Chemistry. 286, 47, p. 40494-40508, 15 p.

    Research output: Contribution to journal › Article

  21. Protein Phosphatase 2A (PP2A)-specific Ubiquitin Ligase MID1 Is a Sequence-dependent Regulator of Translation Efficiency Controlling 3-Phosphoinositide-dependent Protein Kinase-1 (PDPK-1)

    Aranda-Orgilles, B., Rutschow, D., Zeller, R., Karagiannidis, A. I., Koehler, A., Chen, C., Wilson, T., Krause, S., Roepcke, S., Lilley, D., Schneider, R. & Schweiger, S. 18-Nov-2011 In : Journal of Biological Chemistry. 286, 46, p. 39945-39957, 13 p.

    Research output: Contribution to journal › Article

  22. Phosphorylation of the Kinase Interaction Motif in Mitogen-activated Protein (MAP) Kinase Phosphatase-4 Mediates Cross-talk between Protein Kinase A and MAP Kinase Signaling Pathways

    Dickinson, R. J., Delavaine, L., Cejudo-Marin, R., Stewart, G., Staples, C. J., Didmon, M. P., Garcia Trinidad, A., Alonso, A., Pulido, R. & Keyse, S. M. 4-Nov-2011 In : Journal of Biological Chemistry. 286, 44, p. 38018-38026, 9 p.

    Research output: Contribution to journal › Article

  23. Polyubiquitin Binding to Optineurin Is Required for Optimal Activation of TANK-binding Kinase 1 and Production of Interferon beta

    Gleason, C. E., Ordureau, A., Gourlay, R., Arthur, J. S. C. & Cohen, P. 14-Oct-2011 In : Journal of Biological Chemistry. 286, 41, p. 35663-35674, 12 p.

    Research output: Contribution to journal › Article

  24. The inhibitory effect of phospholemman on the sodium pump requires Its palmitoylation

    Tulloch, L. B., Howie, J., Wypijewski, K. J., Wilson, C. R., Bernard, W. G., Shattock, M. J. & Fuller, W. 14-Oct-2011 In : Journal of Biological Chemistry. 286, 41, p. 36020-36031, 12 p.

    Research output: Contribution to journal › Article

  25. Early murine T-lymphocyte activation is accompanied by a switch from N-glycolyl- to N-acetyl-neuraminic acid and generation of ligands for siglec-E

    Redelinghuys, P., Antonopoulos, A., Liu, Y., Campanero-Rhodes, M. A., McKenzie, E., Haslam, S. M., Dell, A., Feizi, T. & Crocker, P. R. 7-Oct-2011 In : Journal of Biological Chemistry. 286, 40, p. 34522-34532, 11 p.

    Research output: Contribution to journal › Article

  26. Low Resolution Structure of a Bacterial SLC26 Transporter Reveals Dimeric Stoichiometry and Mobile Intracellular Domains

    Compton, E. L. R., Karinou, E., Naismith, J. H., Gabel, F. & Javelle, A. 29-Jul-2011 In : Journal of Biological Chemistry. 286, 30, p. 27058-27067, 10 p.

    Research output: Contribution to journal › Article

  27. Bioinformatic Prediction and Confirmation of beta-Adducin as a Novel Substrate of Glycogen Synthase Kinase 3

    Farghaian, H., Turnley, A. M., Sutherland, C. & Cole, A. R. 15-Jul-2011 In : Journal of Biological Chemistry. 286, 28, p. 25274-25283, 10 p.

    Research output: Contribution to journal › Article

  28. Identification of a Proline-rich Inositol Polyphosphate 5-Phosphatase (PIPP)center dot Collapsin Response Mediator Protein 2 (CRMP2) Complex That Regulates Neurite Elongation

    Astle, M. V., Ooms, L. M., Cole, A. R., Binge, L. C., Dyson, J. M., Layton, M. J., Petratos, S., Sutherland, C. & Mitchell, C. A. 1-Jul-2011 In : Journal of Biological Chemistry. 286, 26, p. 23407-23418, 12 p.

    Research output: Contribution to journal › Article

  29. A Systemic Lupus Erythematosus-associated R77H Substitution in the CD11b Chain of the Mac-1 Integrin Compromises Leukocyte Adhesion and Phagocytosis

    MacPherson, M., Lek, H. S., Prescott, A. & Fagerholm, S. C. 13-May-2011 In : Journal of Biological Chemistry. 286, 19, p. 17303-17310, 8 p.

    Research output: Contribution to journal › Article

  30. Rings of Charge within the Extracellular Vestibule Influence Ion Permeation of the 5-HT(3)A Receptor

    Livesey, M. R., Cooper, M. A., Lambert, J. J. & Peters, J. A. 6-May-2011 In : Journal of Biological Chemistry. 286, 18, p. 16008-16017, 10 p.

    Research output: Contribution to journal › Article

  31. A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1

    Narayan, V., Halada, P., Hernychová, L., Chong, Y. P., Žáková, J., Hupp, T. R., Vojtesek, B. & Ball, K. L. 22-Apr-2011 In : Journal of Biological Chemistry. 286, 16, p. 14291-14303, 13 p.

    Research output: Contribution to journal › Article

  32. Selective Expression in Carotid Body Type I Cells of a Single Splice Variant of the Large Conductance Calcium- and Voltage-activated Potassium Channel Confers Regulation by AMP-activated Protein Kinase

    Ross, F. A., Rafferty, J. N., Dallas, M. L., Ogunbayo, O., Ikematsu, N., McClafferty, H., Tian, L., Widmer, H., Rowe, I. C. M., Wyatt, C. N., Shipston, M. J., Peers, C., Hardie, D. G. & Evans, A. M. 8-Apr-2011 In : Journal of Biological Chemistry. 286, 14, p. 11929-11936, 8 p.

    Research output: Contribution to journal › Article

  33. MCM2-7 Form Double Hexamers at Licensed Origins in Xenopus Egg Extract

    Gambus, A., Khoudoli, G. A., Jones, R. C. & Blow, J. J. 1-Apr-2011 In : Journal of Biological Chemistry. 286, 13, p. 11855-11864, 10 p.

    Research output: Contribution to journal › Article

  34. Dissecting the Metabolic Roles of Pteridine Reductase 1 in Trypanosoma brucei and Leishmania major

    Ong, H. B., Sienkiewicz, N., Wyllie, S. & Fairlamb, A. H. 25-Mar-2011 In : Journal of Biological Chemistry. 286, 12, p. 10429-10438, 10 p.

    Research output: Contribution to journal › Article

  35. Antitumor Quinol PMX464 Is a Cytocidal Anti-trypanosomal Inhibitor Targeting Trypanothione Metabolism

    Konig, J., Wyllie, S., Wells, G., Stevens, M. F., Wyatt, P. G. & Fairlamb, A. H. 11-Mar-2011 In : Journal of Biological Chemistry. 286, 10, p. 8523-8533, 11 p.

    Research output: Contribution to journal › Article

  36. Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway

    Deleris, P., Trost, M., Topisirovic, I., Tanguay, P-L., Borden, K. L. B., Thibault, P. & Meloche, S. 25-Feb-2011 In : Journal of Biological Chemistry. 286, 8, p. 6470-6478, 9 p.

    Research output: Contribution to journal › Article

  37. Cooperative Binding and Activation of Fibronectin by a Bacterial Surface Protein

    Marjenberg, Z. R., Ellis, I. R., Hagan, R. M., Prabhakaran, S., Hoeoek, M., Talay, S. R., Potts, J. R., Staunton, D. & Schwarz-Linek, U. 21-Jan-2011 In : Journal of Biological Chemistry. 286, 3, p. 1884-1894, 11 p.

    Research output: Contribution to journal › Article

  38. Docking-dependent ubiquitination of the interferon regulatory factor-1 tumor suppressor protein by the ubiquitin ligase CHIP

    Narayan, V., Pion, E., Landré, V., Müller, P. & Ball, K. L. 7-Jan-2011 In : Journal of Biological Chemistry. 286, 1, p. 607-619, 13 p.

    Research output: Contribution to journal › Article

  39. Functional dissection of Adenylate Cyclase R, an inducer of spore encapsulation

    Chen, Z., Schilde, C. & Schaap, P. 31-Dec-2010 In : Journal of Biological Chemistry. 285, 53, p. 41724-41731, 8 p.

    Research output: Contribution to journal › Article

  40. Intracellular activation of interferon regulatory factor-1 by nanobodies to the multifunctional (Mf1) domain

    Möller, A., Pion, E., Narayan, V. & Ball, K. L. 3-Dec-2010 In : Journal of Biological Chemistry. 285, 49, p. 38348-38361, 14 p.

    Research output: Contribution to journal › Article

  41. Evolution and Multiplicity of Arginine Decarboxylases in Polyamine Biosynthesis and Essential Role in Bacillus subtilis Biofilm Formation

    Burrell, M., Hanfrey, C. C., Murray, E. J., Stanley-Wall, N. R. & Michael, A. J. Dec-2010 In : Journal of Biological Chemistry. 285, 50, p. 39224-39238, 15 p.

    Research output: Contribution to journal › Article

  42. Identification of key functional residues in the active site of human beta 1, 4-Galactosyltransferase 7: a major enzyme in the glycosaminoglycan synthesis pathway

    Talhaoui, I., Bui, C., Oriol, R., Mulliert, G., Gulberti, S., Netter, P., Coughtrie, M. W. H., Ouzzine, M. & Fournel-Gigleux, S. 26-Nov-2010 In : Journal of Biological Chemistry. 285, 48, p. 37342-37358, 17 p.

    Research output: Contribution to journal › Article

  43. An Exceptionally Potent Inducer of Cytoprotective Enzymes elucidation of the structural features that determine inducer potency and reactivity with Keap1

    Dinkova-Kostova, A. T., Talalay, P., Sharkey, J., Zhang, Y., Holtzclaw, W. D., Wang, X. J., David, E., Schiavoni, K. H., Finlayson, S., Mierke, D. F. & Honda, T. 29-Oct-2010 In : Journal of Biological Chemistry. 285, 44, p. 33747-33755, 9 p.

    Research output: Contribution to journal › Article

  44. Cot/tpl2 (MAP3K8) Mediates Myeloperoxidase Activity and Hypernociception following Peripheral Inflammation

    Soria-Castro, I., Krzyzanowska, A., Pelaéz, M. L., Regadera, J., Ferrer, G., Montoliu, L., Rodríguez-Ramos, R., Fernández, M. & Alemany, S. 29-Oct-2010 In : Journal of Biological Chemistry. 285, 44, p. 33805-33815, 11 p.

    Research output: Contribution to journal › Article

  45. RIC-3 Exclusively Enhances the Surface Expression of Human Homomeric 5-Hydroxytryptamine Type 3A (5-HT(3)A) Receptors Despite Direct Interactions with 5-HT3A, -C, -D, and -E Subunits

    Walstab, J., Hammer, C., Lasitschka, F., Moeller, D., Connolly, C. N., Rappold, G., Bruess, M., Boenish, H. & Niesler, B. 27-Aug-2010 In : Journal of Biological Chemistry. 285, 35, p. 26956-26965, 10 p.

    Research output: Contribution to journal › Article

  46. Cross-talk between the p38 alpha and JNK MAPK Pathways Mediated by MAP Kinase Phosphatase-1 Determines Cellular Sensitivity to UV Radiation

    Staples, C. J., Owens, D. M., Maier, J. V., Cato, A. C. B. & Keyse, S. M. 20-Aug-2010 In : Journal of Biological Chemistry. 285, 34, p. 25928-25940, 13 p.

    Research output: Contribution to journal › Article

  47. Two novel Src homology 2 domain proteins interact to regulate Dictyostelium gene expression during growth and early development

    Sugden, C., Ross, S., Bloomfield, G., Ivens, A., Skelton, J., Mueller-Taubenberger, A. & Williams, J. G. 23-Jul-2010 In : Journal of Biological Chemistry. 285, 30, p. 22927-22935, 9 p.

    Research output: Contribution to journal › Article

  48. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription

    Jain, A., Lamark, T., Sjottem, E., Larsen, K. B., Awuh, J. A., Overvatn, A., McMahon, M., Hayes, J. D. & Johansen, T. 16-Jul-2010 In : Journal of Biological Chemistry. 285, 29, p. 22576-22591, 16 p.

    Research output: Contribution to journal › Article

  49. Nuclear DBF-2-related Kinases Are Essential Regulators of Cytokinesis in Bloodstream Stage Trypanosoma brucei

    Ma, J., Benz, C., Grimaldi, R., Stockdale, C., Wyatt, P., Frearson, J. & Hammarton, T. C. 14-May-2010 In : Journal of Biological Chemistry. 285, 20, p. 15356-15368, 13 p.

    Research output: Contribution to journal › Article

  50. Ubiquitination of PTEN (Phosphatase and Tensin Homolog) Inhibits Phosphatase Activity and Is Enhanced by Membrane Targeting and Hyperosmotic Stress

    Maccario, H., Perera, N. M., Gray, A., Downes, C. P. & Leslie, N. R. 23-Apr-2010 In : Journal of Biological Chemistry. 285, 17, p. 12620-12628, 9 p.

    Research output: Contribution to journal › Article

  51. The Snf2 Homolog Fun30 acts as a homodimeric ATP-dependent chromatin-remodeling enzyme

    Awad, S., Ryan, D., Prochasson, P., Owen-Hughes, T. & Hassan, A. H. 26-Mar-2010 In : Journal of Biological Chemistry. 285, 13, p. 9477-9484, 8 p.

    Research output: Contribution to journal › Article

  52. How Escherichia coli is equipped to oxidize hydrogen under different redox conditions

    Lukey, M. J., Parkin, A., Roessler, M. M., Murphy, B. J., Harmer, J., Armstrong, F. A., Palmer, T. & Sargent, F. 5-Feb-2010 In : Journal of Biological Chemistry. 285, 6, p. 3928-3938, 11 p.

    Research output: Contribution to journal › Article

  53. Chemical Validation of Trypanothione Synthetase a potential drug targer for human trypanosomiasis

    Torrie, L. S., Wyllie, S., Spinks, D., Oza, S. L., Thompson, S., Harrison, J. R., Gilbert, I. H., Wyatt, P. G., Fairlamb, A. H. & Frearson, J. A. 25-Dec-2009 In : Journal of Biological Chemistry. 284, 52, p. 36137-36145, 9 p.

    Research output: Contribution to journal › Article

  54. Identification of a novel family of laminin N-terminal alternate splice isoforms structural and functional characterization

    Hamill, K. J., Langbein, L., Jones, J. C. R. & McLean, W. H. I. 18-Dec-2009 In : Journal of Biological Chemistry. 284, 51, p. 35588-35596, 9 p.

    Research output: Contribution to journal › Article

  55. CK1 alpha Plays a Central Role in Mediating MDM2 Control of p53 and E2F-1 Protein Stability

    Huart, A-S., MacLaine, N. J., Meek, D. W. & Hupp, T. R. 20-Nov-2009 In : Journal of Biological Chemistry. 284, 47, p. 32384-32394, 11 p.

    Research output: Contribution to journal › Article

  56. Blom7 alpha Is a Novel Heterogeneous Nuclear Ribonucleoprotein K Homology Domain Protein Involved in Pre-mRNA Splicing That Interacts with SNEVPrp19-Pso4

    Grillari, J., Loescher, M., Denegri, M., Lee, K., Fortschegger, K., Eisenhaber, F., Ajuh, P., Lamond, A. I., Katinger, H. & Grillari-Voglauer, R. 16-Oct-2009 In : Journal of Biological Chemistry. 284, 42, p. 29193-29204, 12 p.

    Research output: Contribution to journal › Article

  57. Cooperative regulation of the interferon regulatory factor-1 tumor suppressor protein by core components of the molecular chaperone machinery

    Narayan, V., Eckert, M., Zylicz, A., Zylicz, M. & Ball, K. L. 18-Sep-2009 In : Journal of Biological Chemistry. 284, 38, p. 25889-25899, 11 p.

    Research output: Contribution to journal › Article

  58. ABC50 promotes translation initiation in mammalian cells

    Paytubi, S., Wang, X., Lam, Y. W., Izquierdo, L., Hunter, M. J., Jan, E., Hundal, H. S. & Proud, C. G. 4-Sep-2009 In : Journal of Biological Chemistry. 284, 36, p. 24061-24073, 13 p.

    Research output: Contribution to journal › Article

  59. Keep Nibbling at the Edges

    Cohen, P. 4-Sep-2009 In : Journal of Biological Chemistry. 284, 36, p. 23891-23901, 11 p.

    Research output: Contribution to journal › Editorial

  60. Phosphorylation of histone H3 Thr-45 is linked to apoptosis

    Hurd, P. J., Bannister, A. J., Halls, K., Dawson, M. A., Vermeulen, M., Olsen, J. V., Ismail, H., Somers, J., Mann, M., Owen-Hughes, T., Gout, I. & Kouzarides, T. 12-Jun-2009 In : Journal of Biological Chemistry. 284, 24, p. 16575-16583, 9 p.

    Research output: Contribution to journal › Article

  61. Angiotensin-converting enzyme Ii a modifier of hypertensive end organ damage

    Liu, X., Bellamy, C. O. C., Bailey, M. A., Mullins, L. J., Dunbar, D. R., Kenyon, C. J., Brooker, G., Kantachuvesiri, S., Maratou, K., Ashek, A., Clark, A. F., Fleming, S. & Mullins, J. J. 5-Jun-2009 In : Journal of Biological Chemistry. 284, 23, p. 15564-15572, 9 p.

    Research output: Contribution to journal › Article

  62. Motogenic Sites in Human Fibronectin Are Masked by Long Range Interactions

    Vakonakis, I., Staunton, D., Ellis, I. R., Sarkies, P., Flanagan, A., Schor, A. M., Schor, S. L. & Campbell, I. D. 5-Jun-2009 In : Journal of Biological Chemistry. 284, 23, p. 15668-15675, 8 p.

    Research output: Contribution to journal › Article

  63. Use of the Pharmacological Inhibitor BX795 to Study the Regulation and Physiological Roles of TBK1 and I kappa B Kinase epsilon A DISTINCT UPSTREAM KINASE MEDIATES SER-172 PHOSPHORYLATION AND ACTIVATION

    Clark, K., Plater, L., Peggie, M. & Cohen, P. 22-May-2009 In : Journal of Biological Chemistry. 284, 21, p. 14136-14146, 11 p.

    Research output: Contribution to journal › Article

  64. Structure-based ligand design and the promise held for antiprotozoan drug discovery

    Hunter, W. N. 1-May-2009 In : Journal of Biological Chemistry. 284, 18, p. 11749-11753, 5 p.

    Research output: Contribution to journal › Scientific review

  65. ULK1 center dot ATG13 center dot FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

    Ganley, I. G., Lam, D. H., Wang, J., Ding, X., Chen, S. & Jiang, X. 1-May-2009 In : Journal of Biological Chemistry. 284, 18, p. 12297-12305, 9 p.

    Research output: Contribution to journal › Article

  66. RIG-I-mediated activation of p38 MAPK is essential for viral induction of interferon and activation of dendritic cells: dependence on TRAF2 and TAK1

    Mikkelsen, S. S., Jensen, S. B., Chiliveru, S., Melchjorsen, J., Julkunen, I., Gaestel, M., Arthur, J. S. C., Flavell, R. A., Ghosh, S. & Paludan, S. R. 17-Apr-2009 In : Journal of Biological Chemistry. 284, 16, p. 10774-10782, 9 p.

    Research output: Contribution to journal › Article

  67. Leptin-dependent Phosphorylation of PTEN Mediates Actin Restructuring and Activation of ATP-sensitive K+ Channels

    Ning, K., Miller, L. C., Laidlaw, H. A., Watterson, K. R., Gallagher, J., Sutherland, C. & Ashford, M. L. J. 3-Apr-2009 In : Journal of Biological Chemistry. 284, 14, p. 9331-9340, 10 p.

    Research output: Contribution to journal › Article

  68. Molecular mechanisms of yeast cell wall glucan remodeling

    Hurtado-Guerrero, R., Schuettelkopf, A. W., Mouyna, I., Ibrahim, A. F. M., Shepherd, S., Fontaine, T., Latge, J-P. & van Aalten, D. M. F. 27-Mar-2009 In : Journal of Biological Chemistry. 284, 13, p. 8461-8469, 9 p.

    Research output: Contribution to journal › Article

  69. Enhancing the receptor affinity of the sialic acid-binding domain of Vibrio cholerae sialidase through multivalency

    Connaris, H., Crocker, P. R. & Taylor, G. L. 13-Mar-2009 In : Journal of Biological Chemistry. 284, 11, p. 7339-7351, 13 p.

    Research output: Contribution to journal › Article

  70. Basic Residues Are Critical to the Activity of Peptide Inhibitors of Human T Cell Leukemia Virus Type 1 Entry

    Lamb, D., Mirsaliotis, A., Kelly, S. M. & Brighty, D. W. 6-Mar-2009 In : Journal of Biological Chemistry. 284, 10, p. 6575-6584, 10 p.

    Research output: Contribution to journal › Article

  71. Mechanistic Insight into Control of CFTR by AMPK

    Kongsuphol, P., Cassidy, D., Hieke, B., Treharne, K. J., Schreiber, R., Mehta, A. & Kunzelmann, K. 27-Feb-2009 In : Journal of Biological Chemistry. 284, 9, p. 5645-5653, 9 p.

    Research output: Contribution to journal › Article

  72. Suppression of the Deubiquitinating Enzyme USP5 Causes the Accumulation of Unanchored Polyubiquitin and the Activation of p53

    Dayal, S., Sparks, A., Jacob, J., Allende-Vega, N., Lane, D. & Saville, M. K. 20-Feb-2009 In : Journal of Biological Chemistry. 284, 8, p. 5030-5041, 12 p.

    Research output: Contribution to journal › Article

  73. SWI/SNF regulates the cellular response to hypoxia

    Kenneth, N. S., Mudie, S., van Uden, P. & Rocha, S. 13-Feb-2009 In : Journal of Biological Chemistry. 284, 7, p. 4123-4131, 9 p.

    Research output: Contribution to journal › Article

  74. The Nrf3 transcription factor is a membrane-bound glycoprotein targeted to the endoplasmic reticulum through Its N-terminal Homology Box 1 Sequence

    Zhang, Y., Kobayashi, A., Yamamoto, M. & Hayes, J. D. 30-Jan-2009 In : Journal of Biological Chemistry. 284, 5, p. 3195-3210, 16 p.

    Research output: Contribution to journal › Article

  75. Characterization of the Effects of Charged Residues in the Intracellular Loop on Ion Permeation in alpha 1 Glycine Receptor Channels

    Carland, J. E., Cooper, M. A., Sugiharto, S., Jeong, H-J., Lewis, T. M., Barry, P. H., Peters, J. A., Lambert, J. J. & Moorhouse, A. J. 23-Jan-2009 In : Journal of Biological Chemistry. 284, 4, p. 2023-2030, 8 p.

    Research output: Contribution to journal › Article

  76. TGF-beta Induces Growth Arrest in Burkitt Lymphoma Cells via Transcriptional Repression of E2F-1

    Spender, L. C. & Inman, G. J. 16-Jan-2009 In : Journal of Biological Chemistry. 284, 3, p. 1435-1442, 8 p.

    Research output: Contribution to journal › Article

  77. ABF1-binding sites promote efficient global genome nucleotide excision repair

    Yu, S., Smirnova, J. B., Friedberg, E. C., Stillman, B., Akiyama, M., Owen-Hughes, T., Waters, R. & Reed, S. H. 9-Jan-2009 In : Journal of Biological Chemistry. 284, 2, p. 966-973, 8 p.

    Research output: Contribution to journal › Article

  78. C-terminal Phosphorylation of LKB1 Is Not Required for Regulation of AMP-activated Protein Kinase, BRSK1, BRSK2, or Cell Cycle Arrest

    Fogarty, S. & Hardie, D. G. 2-Jan-2009 In : Journal of Biological Chemistry. 284, 1, p. 77-84, 8 p.

    Research output: Contribution to journal › Article

  79. Docking of PRAK/MK5 to the atypical MAPKs ERK3 and ERK4 defines a novel MAPK interaction motif

    Aberg, E., Torgersen, K. M., Johansen, B., Keyse, S. M., Perander, M. & Seternes, O-M. 2009 In : Journal of Biological Chemistry. 284, 29, p. 19392-401, 10 p.

    Research output: Contribution to journal › Article

  80. Protein Kinase C-mediated Phosphorylation and activation of PDE3A Regulate cAMP levels in human platelets

    Hunter, R., MacKintosh, C. & Hers, I. 2009 In : Journal of Biological Chemistry. 284, 18, p. 12339-12348, 10 p.

    Research output: Contribution to journal › Article

  81. FANCJ Is a Structure-specific DNA Helicase Associated with the Maintenance of Genomic G/C Tracts

    London, T. B. C., Barber, L. J., Mosedale, G., Kelly, G. P., Balasubramanian, S., Hickson, I. D., Boulton, S. J. & Hiom, K. 26-Dec-2008 In : Journal of Biological Chemistry. 283, 52, p. 36132-36139, 8 p.

    Research output: Contribution to journal › Article

  82. Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes

    Ohtsuji, M., Katsuoka, F., Kobayashi, A., Aburatani, H., Hayes, J. D. & Yamamoto, M. 28-Nov-2008 In : Journal of Biological Chemistry. 283, 48, p. 33554-33562, 9 p.

    Research output: Contribution to journal › Article

  83. Defining the in Vivo Role for Cytochrome b(5) in Cytochrome P450 Function through the Conditional Hepatic Deletion of Microsomal Cytochrome b(5)

    Finn, R. D., McLaughlin, L. A., Ronseaux, S., Rosewell, I., Houston, J. B., Henderson, C. J. & Wolf, C. R. 14-Nov-2008 In : Journal of Biological Chemistry. 283, 46, p. 31385-31393, 9 p.

    Research output: Contribution to journal › Article

  84. Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment

    Mace, P. D., Linke, K., Feltham, R., Schumacher, F-R., Smith, C. A., Vaux, D. L., Silke, J. & Day, C. L. 14-Nov-2008 In : Journal of Biological Chemistry. 283, 46, p. 31633-31640, 8 p.

    Research output: Contribution to journal › Article

  85. A central role for CK1 in catalyzing phosphorylation of the p53 transactivation domain at serine 20 after HHV-6B viral infection

    MacLaine, N. J., Oster, B., Bundgaard, B., Fraser, J. A., Buckner, C., Lazo, P. A., Meek, D. W., Hoellsberg, P. & Hupp, T. R. 17-Oct-2008 In : Journal of Biological Chemistry. 283, 42, p. 28563-28573, 11 p.

    Research output: Contribution to journal › Article

  86. Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake

    Green, C. J., Goransson, O., Kular, G. S., Leslie, N. R., Gray, A., Alessi, D. R., Sakamoto, K. & Hundal, H. S. 10-Oct-2008 In : Journal of Biological Chemistry. 283, 41, p. 27653-27667, 15 p.

    Research output: Contribution to journal › Article

  87. DsbA plays a critical and multifaceted role in the production of secreted virulence factors by the phytopathogen Erwinia carotovora subsp atroseptica

    Coulthurst, S. J., Lilley, K. S., Hedley, P. E., Liu, H., Toth, I. K. & Salmond, G. P. C. 29-Aug-2008 In : Journal of Biological Chemistry. 283, 35, p. 23739-23753, 15 p.

    Research output: Contribution to journal › Article

  88. Phosphatidylethanolamine in Trypanosoma brucei is organized in two separate pools and is synthesized exclusively by the Kennedy pathway

    Signorell, A., Rauch, M., Jelk, J., Ferguson, M. A. J. & Buetikofer, P. 29-Aug-2008 In : Journal of Biological Chemistry. 283, 35, p. 23636-23644, 9 p.

    Research output: Contribution to journal › Article

  89. Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor

    Livesey, M. R., Cooper, M. A., Deeb, T. Z., Carland, J. E., Kozuska, J., Hales, T. G., Lambert, J. J. & Peters, J. A. 11-Jul-2008 In : Journal of Biological Chemistry. 283, 28, p. 19301-19313, 13 p.

    Research output: Contribution to journal › Article

  90. The scaffold MyD88 acts to couple protein kinase C epsilon to toll-like receptors

    Faisal, A., Saurin, A., Gregory, B., Foxwell, B. & Parker, P. J. 4-Jul-2008 In : Journal of Biological Chemistry. 283, 27, p. 18591-18600, 10 p.

    Research output: Contribution to journal › Article

  91. Elevated levels of oncogenic protein kinase pim-1 induce the p53 pathway in cultured cells and correlate with increased mdm2 in mantle cell lymphoma

    Hogan, C., Hutchison, C., Marcar, L., Milne, D., Saville, M., Goodlad, J., Kernohan, N. & Meek, D. 27-Jun-2008 In : Journal of Biological Chemistry. 283, 26, p. 18012-18023, 12 p.

    Research output: Contribution to journal › Article

  92. Relative resistance of Cdk5-phosphorylated CRMP2 to dephosphorylation

    Cole, A. R., Soutar, M. P. M., Rembutsu, M., van Aalten, L., Hastie, C. J., Mclauchlan, H., Peggie, M., Balastik, M., Lu, K. P. & Sutherland, C. 27-Jun-2008 In : Journal of Biological Chemistry. 283, 26, p. 18227-18237, 11 p.

    Research output: Contribution to journal › Article

  93. A common theme in interaction of bacterial immunoglobulin-binding proteins with immunoglobulins illustrated in the equine system

    Lewis, M. J., Meehan, M., Owen, P. & Woof, J. M. 20-Jun-2008 In : Journal of Biological Chemistry. 283, 25, p. 17615-17623, 9 p.

    Research output: Contribution to journal › Article

  94. Leishmania trypanothione synthetase-amidase structure reveals a basis for regulation of conflicting synthetic and hydrolytic activities

    Fyfe, P. K., Oza, S. L., Fairlamb, A. H. & Hunter, W. N. 20-Jun-2008 In : Journal of Biological Chemistry. 283, 25, p. 17672-17680, 9 p.

    Research output: Contribution to journal › Article

  95. The synthesis of UDP-N-acetylglucosamine is essential for bloodstream form Trypanosoma brucei in vitro and in vivo and UDP-N-acetylglucosamine starvation reveals a hierarchy in parasite protein glycosylation

    Stokes, M. J., Guther, M. L. S., Turnock, D. C., Prescott, A. R., Martin, K. L., Alphey, M. S. & Ferguson, M. A. J. 6-Jun-2008 In : Journal of Biological Chemistry. 283, 23, p. 16147-16161, 15 p.

    Research output: Contribution to journal › Article

  96. The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior

    Lee, H., Cho, J. S., Lambacher, N., Lee, J., Lee, S-J., Lee, T. H., Gartner, A. & Koo, H-S. 30-May-2008 In : Journal of Biological Chemistry. 283, 22, p. 14988-14993, 6 p.

    Research output: Contribution to journal › Article

  97. Regulation of the epithelial Na+ channel by the protein kinase CK2

    Bachhuber, T., Almaca, J., Aldehni, F., Mehta, A., Amaral, M. D., Schreiber, R. & Kunzelmann, K. 9-May-2008 In : Journal of Biological Chemistry. 283, 19, p. 13225-13232, 8 p.

    Research output: Contribution to journal › Article

  98. The docking interaction of caspase-9 with ERK2 provides a mechanism for the selective inhibitory phosphorylation of caspase-9 at threonine 125

    Martin, M. C., Allan, L. A., Mancini, E. J. & Clarke, P. R. 15-Feb-2008 In : Journal of Biological Chemistry. 283, 7, p. 3854-3865, 12 p.

    Research output: Contribution to journal › Article

  99. 3-phosphoinositide-dependent kinase 1 deficiency perturbs toll-like receptor signaling events and actin cytoskeleton dynamics in dendritic cells

    Zaru, R., Mollahan, P. & Watts, C. 11-Jan-2008 In : Journal of Biological Chemistry. 283, 2, p. 929-939, 11 p.

    Research output: Contribution to journal › Article

  100. Rosiglitazone stimulates nitric oxide synthesis in human aortic endothelial cells via AMP-activated protein kinase

    Boyle, J. G., Logan, P. J., Ewart, M-A., Reihill, J. A., Ritchie, S. A., Connell, J. M. C., Cleland, S. J. & Salt, I. P. 2008 In : Journal of Biological Chemistry. 283, 17, p. 11210-11217, 8 p.

    Research output: Contribution to journal › Article

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