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  1. Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling

    Moreno, E., Andradas, C., Medrano, M., Caffarel, M. M., Pérez-Gómez, E., Blasco-Benito, S., Gómez-Cañas, M., Pazos, M. R., Irving, A. J., Lluís, C., Canela, E. I., Fernández-Ruiz, J., Guzmán, M., McCormick, P. J. & Sánchez, C. 8 Aug 2014 In : Journal of Biological Chemistry. 289, p. 21960-21972 12 p.

    Research output: Contribution to journalArticle

  2. Siglec-E promotes β2-integrin-dependent NADPH oxidase activation to suppress neutrophil recruitment to the lung

    McMillan, S. J., Sharma, R. S., Richards, H. E., Hegde, V. & Crocker, P. R. 18 Jul 2014 In : Journal of Biological Chemistry. 289, 29, p. 20370-20376 7 p.

    Research output: Contribution to journalArticle

  3. Molecular cloning and functional characterization of components of the capsule biosynthesis complex of Neisseria meningitidis serogroup A: toward in vitro vaccine production

    Fiebig, T., Freiberger, F., Pinto, V., Romano, M. R., Black, A., Litschko, C., Bethe, A., Yashunsky, D., Adamo, R., Nikolaev, A., Berti, F. & Gerardy-Schahn, R. 11 Jul 2014 In : Journal of Biological Chemistry. 289, 28, p. 19395-19407 13 p.

    Research output: Contribution to journalArticle

  4. Identification and functional characterization of a highly divergent N-acetylglucosaminyltransferase I (TbGnTI) in Trypanosoma brucei

    Damerow, M., Rodrigues, J. A., Wu, D., Güther, M. L. S., Mehlert, A. & Ferguson, M. A. J. 28 Mar 2014 In : Journal of Biological Chemistry. 289, 13, p. 9328-9339 12 p.

    Research output: Contribution to journalArticle

  5. 5-HT cellular sequestration during chronic exposure delays 5-HT3 receptor resensitization due to its subsequent release

    Hothersall, J. D., Alexander, A., Samson, A. J., Moffat, C., Bollan, K. A. & Connolly, C. N. 2014 In : Journal of Biological Chemistry. 20 p.

    Research output: Contribution to journalArticle

  6. A structural and biochemical model of processive chitin synthesis

    Dorfmueller, H. C., Ferenbach, A. T., Borodkin, V. S. & van Aalten, D. M. F. 2014 In : Journal of Biological Chemistry.

    Research output: Contribution to journalArticle

  7. Identification of small molecule inhibitors of pre-mRNA splicing

    Pawellek, A., McElroy, S., Samatov, T., Mitchell, L., Woodland, A., Ryder, U., Gray, D., Lührmann, R. & Lamond, A. I. 2014 In : Journal of Biological Chemistry. 29 p.

    Research output: Contribution to journalArticle

  8. O-GlcNAcase: promiscuous hexosaminidase or key regulator of O-GlcNAc signalling?

    Alonso , J., Schimpl, M. & van Aalten, D. M. F. 2014 In : Journal of Biological Chemistry. 16 p.

    Research output: Contribution to journalArticle

  9. Mutagenic analysis of the intracellular portals of the human 5-HT3A receptor

    Carland, J. E., Cooper, M. A., Livesey, M. R., Hales, T. G., Lambert, J. J. & Peters, J. A. 1 Nov 2013 In : Journal of Biological Chemistry. 288, 44, p. 31592-31601 10 p.

    Research output: Contribution to journalArticle

  10. The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing

    Caillat, C., Pefani, D-E., Gillespie, P. J., Taraviras, S., Blow, J. J., Lygerou, Z. & Perrakis, A. Nov 2013 In : Journal of Biological Chemistry. 288, 44, p. 31624-31634 11 p.

    Research output: Contribution to journalArticle

  11. DEAF1 is a Pellino1-interacting protein required for interferon production by Sendai virus and double-stranded RNA

    Ordureau, A., Enesa, K., Nanda, S., Le Francois, B., Peggie, M., Prescott, A., Albert, P. R. & Cohen, P. 23 Aug 2013 In : Journal of Biological Chemistry. 288, 34, p. 24569-24580 12 p.

    Research output: Contribution to journalArticle

  12. The minimum M3-M4 loop length of neurotransmitteractivated pentameric receptors is critical for the structural integrity of cytoplasmic portals

    Baptista-Hon, D. T., Deeb, T. Z., Lambert, J. J., Peters, J. A. & Hales, T. G. 26 Jul 2013 In : Journal of Biological Chemistry. 288, 30, p. 21558-21568 11 p.

    Research output: Contribution to journalArticle

  13. The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow

    Lek, H. S., Morrison, V. L., Conneely, M., Campbell, P. A., McGloin, D., Kliche, S., Watts, C., Prescott, A. & Fagerholm, S. C. 24 May 2013 In : Journal of Biological Chemistry. 288, 21, p. 14698-14708 11 p.

    Research output: Contribution to journalArticle

  14. A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

    Wypijewski, K. J., Howie, J., Reilly, L., Tulloch, L. B., Aughton, K. L., McLatchie, L. M., Shattock, M. J., Calaghan, S. C. & Fuller, W. 10 May 2013 In : Journal of Biological Chemistry. 288, 19, p. 13808-13820 13 p.

    Research output: Contribution to journalArticle

  15. Structure of a complex phosphoglycan epitope from gp72 of Trypanosoma cruzi

    Allen, S., Richardson, J. M., Mehlert, A. & Ferguson, M. A. J. 19 Apr 2013 In : Journal of Biological Chemistry. 288, 16, p. 11093-11105 13 p.

    Research output: Contribution to journalArticle

  16. Ca2+ signalling through CatSper and Ca2+ stores regulate different behaviours in human sperm

    Alasmari, W., Costello, S., Correia, J., Oxenham, S. K., Morris, J., Fernandes, L., Ramalho Santos, J., Kirkman-Brown, J., Michelangeli, F., Publicover, S. & Barratt, C. L. R. 1 Mar 2013 In : Journal of Biological Chemistry. 288, 9, p. 6248-6258 11 p.

    Research output: Contribution to journalArticle

  17. Dual regulation of Glycogen Synthase Kinase 3 (GSK3)alpha/beta by Protein Kinase C (PKC)alpha and Akt promotes Thrombin-mediated Integrin alpha(IIb)beta(3) activation and granule secretion in platelets

    Moore, S. F., van den Bosch, M. T. J., Hunter, R. W., Sakamoto, K., Poole, A. W. & Hers, I. 2013 In : Journal of Biological Chemistry. 288, 6, p. 3918-3928 11 p.

    Research output: Contribution to journalArticle

  18. N-terminal serine dephosphorylation is required for KCC3 cotransporter full activation by cell swelling

    Melo, Z., De Los Heros, P., Cruz-Rangel, S., Vázquez, N., Bobadilla, N. A., Pasantes-Morales, H., Alessi, D. R., Mercado, A. & Gamba, G. 2013 In : Journal of Biological Chemistry. 288, 44, p. 31468-31476 9 p.

    Research output: Contribution to journalArticle

  19. The involvement of mitochondrial amidoxime reducing components 1 and 2 and mitochondrial cytochrome b5 in N-reductive metabolism in human cells

    Plitzko, B., Ott, G., Reichmann, D., Henderson, C. J., Wolf, C. R., Mendel, R., Bittner, F., Clement, B. & Havemeyer, A. 2013 In : Journal of Biological Chemistry. 288, 28, p. 20228-20237 10 p.

    Research output: Contribution to journalArticle

  20. Family with Sequence Similarity 60A (FAM60A) Protein Is a Cell Cycle-fluctuating Regulator of the SIN3-HDAC1 Histone Deacetylase Complex

    Munoz, I. M., Macartney, T., Sanchez-Pulido, L., Ponting, C. P., Rocha, S. & Rouse, J. 21 Sep 2012 In : Journal of Biological Chemistry. 287, 39, p. 32346-53 8 p.

    Research output: Contribution to journalArticle

  21. Monoubiquitination Promotes Calpain Cleavage of the Protein Phosphatase 2A (PP2A) Regulatory Subunit alpha 4, Altering PP2A Stability and Microtubule-associated Protein Phosphorylation

    Watkins, G. R., Wang, N., Mazalouskas, M. D., Gomez, R. J., Guthrie, C. R., Kraemer, B. C., Schweiger, S., Spiller, B. W. & Wadzinski, B. E. 13 Jul 2012 In : Journal of Biological Chemistry. 287, 29, p. 24207-24215 9 p.

    Research output: Contribution to journalArticle

  22. A conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome

    Kilkenny, M. L., De Piccoli, G., Perera, R. L., Labib, K. & Pellegrini, L. 6 Jul 2012 In : Journal of Biological Chemistry. 287, 28, p. 23740-23747 8 p.

    Research output: Contribution to journalArticle

  23. IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold

    Dixon, M. J., Gray, A., Schenning, M., Agacan, M., Tempel, W., Tong, Y., Nedyalkova, L., Park, H-W., Leslie, N. R., van Aalten, D. M. F., Downes, C. P. & Batty, I. H. 29 Jun 2012 In : Journal of Biological Chemistry. 287, 27, p. 22483-22496 14 p.

    Research output: Contribution to journalArticle

  24. Defining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cells

    Turban, S., Stretton, C., Drouin, O., Green, C. J., Watson, M. L., Gray, A., Ross, F., Lantier, L., Viollet, B., Hardie, D. G., Marette, A. & Hundal, H. S. 8 Jun 2012 In : Journal of Biological Chemistry. 287, 24, p. 20088-20099 12 p.

    Research output: Contribution to journalArticle

  25. Essential Role for IKK beta in Production of Type 1 Interferons by Plasmacytoid Dendritic Cells

    Pauls, E., Shpiro, N., Peggie, M., Young, E. R., Sorcek, R. J., Tan, L., Choi, H. G. & Cohen, P. 1 Jun 2012 In : Journal of Biological Chemistry. 287, 23, p. 19216-19228 13 p.

    Research output: Contribution to journalArticle

  26. Escherichia coli TatA and TatB Proteins Have N-out, C-in Topology in Intact Cells

    Koch, S., Fritsch, M. J., Buchanan, G. & Palmer, T. 27 Apr 2012 In : Journal of Biological Chemistry. 287, 18, p. 14420-14431 12 p.

    Research output: Contribution to journalArticle

  27. Distinct control of MyD88 adapter-dependent and Akt kinase-regulated responses by the interleukin (IL)-1RI co-receptor, TILRR

    Zhang, X., Montagut Pino, G., Shephard, F., Kiss-Toth, E. & Qwarnstrom, E. E. 6 Apr 2012 In : Journal of Biological Chemistry. 287, 15, p. 12348-12352 5 p.

    Research output: Contribution to journalArticle

  28. Phosphorylation of FOXO3a on Ser-7 by p38 promotes its nuclear localization in response to doxorubicin

    Ho, K-K., McGuire, V. A., Koo, C-Y., Muir, K. W., de Olano, N., Maifoshie, E., Kelly, D. J., McGovern, U. B., Monteiro, L. J., Gomes, A. R., Nebreda, A. R., Campbell, D. G., Arthur, J. S. C. & Lam, E. W. -F. 6 Jan 2012 In : Journal of Biological Chemistry. 287, 2, p. 1545-1555 11 p.

    Research output: Contribution to journalArticle

  29. Modulation of L-alpha-Lysophosphatidylinositol/GPR55 Mitogen-activated Protein Kinase (MAPK) Signaling by Cannabinoids

    Anavi-Goffer, S., Baillie, G., Irving, A. J., Gertsch, J., Greig, I. R., Pertwee, R. G. & Ross, R. A. 2 Jan 2012 In : Journal of Biological Chemistry. 287, 1, p. 91-104 14 p.

    Research output: Contribution to journalArticle

  30. Avirulence protein 3a (AVR3a) from the potato pathogen Phytophthora infestans forms homodimers through its predicted translocation region and does not specifically bind phospholipids

    Wawra, S., Agacan, M., Boddey, J. A., Davidson, I., Gachon, C. M. M., Zanda, M., Grouffaud, S., Whisson, S. C., Birch, P. R. J., Porter, A. J. & Van West, P. 2012 In : Journal of Biological Chemistry. 287, 45, p. 38101-38109 9 p.

    Research output: Contribution to journalArticle

  31. Pellino1 Is Required for Interferon Production by Viral Double-stranded RNA

    Enesa, K., Ordureau, A., Smith, H., Barford, D., Cheung, P. C. F., Patterson-Kane, J., Arthur, J. S. C. & Cohen, P. 2012 In : Journal of Biological Chemistry. 287, 41, p. 34825-34835 11 p.

    Research output: Contribution to journalArticle

  32. Role of binding and nucleoside diphosphate kinase A in the regulation of the cystic fibrosis transmembrane conductance regulator by AMP-activated protein kinase

    King, J. D., Lee, J., Riemen, C. E., Neumann, D., Xiong, S., Foskett, J. K., Mehta, A., Muimo, R. & Hallows, K. R. 2012 In : Journal of Biological Chemistry. 287, 40, p. 33389-33400 12 p.

    Research output: Contribution to journalArticle

  33. Transforming Growth Factor-β directly induces PUMA during the rapid induction of apoptosis in Myc-driven B-cell lymphomas.

    Spender, L. C., Carter, M. J., O'Brien, D. I., Clark, L. J., Yu, J., Michalak, E. M., Happo, L., Cragg, M. S. & Inman, G. J. 2012 In : Journal of Biological Chemistry.

    Research output: Contribution to journalArticle

  34. Distinct Docking Mechanisms Mediate Interactions between the Msg5 Phosphatase and Mating or Cell Integrity Mitogen-activated Protein Kinases (MAPKs) in Saccharomyces cerevisiae

    Palacios, L., Dickinson, R. J., Sacristan-Reviriego, A., Didmon, M. P., Jose Marin, M., Martin, H., Keyse, S. M. & Molina, M. 9 Dec 2011 In : Journal of Biological Chemistry. 286, 49, p. 42037-42050 14 p.

    Research output: Contribution to journalArticle

  35. Internalization of Exogenous Cystatin F Supresses Cysteine Proteases and Induces the Accumulation of Single-chain Cathepsin L by Multiple Mechanisms

    Colbert, J. D., Matthews, S. P., Kos, J. & Watts, C. 9 Dec 2011 In : Journal of Biological Chemistry. 286, 49, p. 42082-42090 9 p.

    Research output: Contribution to journalArticle

  36. Chemical structure of Trichomonas vaginalis surface lipoglycan: a role for short galactose (beta 1-4/3) N-acetylglucosamine repeats in host cell interaction

    Ryan, C. M., Mehlert, A., Richardson, J. M., Ferguson, M. A. J. & Johnson, P. J. 25 Nov 2011 In : Journal of Biological Chemistry. 286, 47, p. 40494-40508 15 p.

    Research output: Contribution to journalArticle

  37. Protein Phosphatase 2A (PP2A)-specific Ubiquitin Ligase MID1 Is a Sequence-dependent Regulator of Translation Efficiency Controlling 3-Phosphoinositide-dependent Protein Kinase-1 (PDPK-1)

    Aranda-Orgilles, B., Rutschow, D., Zeller, R., Karagiannidis, A. I., Köhler, A., Chen, C., Wilson, T., Krause, S., Roepcke, S., Lilley, D., Schneider, R. & Schweiger, S. 18 Nov 2011 In : Journal of Biological Chemistry. 286, 46, p. 39945-39957 13 p.

    Research output: Contribution to journalArticle

  38. Phosphorylation of the Kinase Interaction Motif in Mitogen-activated Protein (MAP) Kinase Phosphatase-4 Mediates Cross-talk between Protein Kinase A and MAP Kinase Signaling Pathways

    Dickinson, R. J., Delavaine, L., Cejudo-Marin, R., Stewart, G., Staples, C. J., Didmon, M. P., Garcia Trinidad, A., Alonso, A., Pulido, R. & Keyse, S. M. 4 Nov 2011 In : Journal of Biological Chemistry. 286, 44, p. 38018-38026 9 p.

    Research output: Contribution to journalArticle

  39. Polyubiquitin Binding to Optineurin Is Required for Optimal Activation of TANK-binding Kinase 1 and Production of Interferon beta

    Gleason, C. E., Ordureau, A., Gourlay, R., Arthur, J. S. C. & Cohen, P. 14 Oct 2011 In : Journal of Biological Chemistry. 286, 41, p. 35663-35674 12 p.

    Research output: Contribution to journalArticle

  40. The inhibitory effect of phospholemman on the sodium pump requires Its palmitoylation

    Tulloch, L. B., Howie, J., Wypijewski, K. J., Wilson, C. R., Bernard, W. G., Shattock, M. J. & Fuller, W. 14 Oct 2011 In : Journal of Biological Chemistry. 286, 41, p. 36020-36031 12 p.

    Research output: Contribution to journalArticle

  41. Early murine T-lymphocyte activation is accompanied by a switch from N-glycolyl- to N-acetyl-neuraminic acid and generation of ligands for siglec-E

    Redelinghuys, P., Antonopoulos, A., Liu, Y., Campanero-Rhodes, M. A., McKenzie, E., Haslam, S. M., Dell, A., Feizi, T. & Crocker, P. R. 7 Oct 2011 In : Journal of Biological Chemistry. 286, 40, p. 34522-34532 11 p.

    Research output: Contribution to journalArticle

  42. Structural analysis of human FANCL, the E3 ligase in the Fanconi anemia pathway

    Hodson, C., Cole, A. R., Lewis, L. P. C., Miles, J. A., Purkiss, A. & Walden, H. 16 Sep 2011 In : Journal of Biological Chemistry. 286, 37, p. 32628-32637 10 p.

    Research output: Contribution to journalArticle

  43. Low Resolution Structure of a Bacterial SLC26 Transporter Reveals Dimeric Stoichiometry and Mobile Intracellular Domains

    Compton, E. L. R., Karinou, E., Naismith, J. H., Gabel, F. & Javelle, A. 29 Jul 2011 In : Journal of Biological Chemistry. 286, 30, p. 27058-27067 10 p.

    Research output: Contribution to journalArticle

  44. Bioinformatic Prediction and Confirmation of beta-Adducin as a Novel Substrate of Glycogen Synthase Kinase 3

    Farghaian, H., Turnley, A. M., Sutherland, C. & Cole, A. R. 15 Jul 2011 In : Journal of Biological Chemistry. 286, 28, p. 25274-25283 10 p.

    Research output: Contribution to journalArticle

  45. Identification of a Proline-rich Inositol Polyphosphate 5-Phosphatase (PIPP)center dot Collapsin Response Mediator Protein 2 (CRMP2) Complex That Regulates Neurite Elongation

    Astle, M. V., Ooms, L. M., Cole, A. R., Binge, L. C., Dyson, J. M., Layton, M. J., Petratos, S., Sutherland, C. & Mitchell, C. A. 1 Jul 2011 In : Journal of Biological Chemistry. 286, 26, p. 23407-23418 12 p.

    Research output: Contribution to journalArticle

  46. A Systemic Lupus Erythematosus-associated R77H Substitution in the CD11b Chain of the Mac-1 Integrin Compromises Leukocyte Adhesion and Phagocytosis

    MacPherson, M., Lek, H. S., Prescott, A. & Fagerholm, S. C. 13 May 2011 In : Journal of Biological Chemistry. 286, 19, p. 17303-17310 8 p.

    Research output: Contribution to journalArticle

  47. Rings of Charge within the Extracellular Vestibule Influence Ion Permeation of the 5-HT(3)A Receptor

    Livesey, M. R., Cooper, M. A., Lambert, J. J. & Peters, J. A. 6 May 2011 In : Journal of Biological Chemistry. 286, 18, p. 16008-16017 10 p.

    Research output: Contribution to journalArticle

  48. A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1

    Narayan, V., Halada, P., Hernychová, L., Chong, Y. P., Žáková, J., Hupp, T. R., Vojtesek, B. & Ball, K. L. 22 Apr 2011 In : Journal of Biological Chemistry. 286, 16, p. 14291-14303 13 p.

    Research output: Contribution to journalArticle

  49. Selective Expression in Carotid Body Type I Cells of a Single Splice Variant of the Large Conductance Calcium- and Voltage-activated Potassium Channel Confers Regulation by AMP-activated Protein Kinase

    Ross, F. A., Rafferty, J. N., Dallas, M. L., Ogunbayo, O., Ikematsu, N., McClafferty, H., Tian, L., Widmer, H., Rowe, I. C. M., Wyatt, C. N., Shipston, M. J., Peers, C., Hardie, D. G. & Evans, A. M. 8 Apr 2011 In : Journal of Biological Chemistry. 286, 14, p. 11929-11936 8 p.

    Research output: Contribution to journalArticle

  50. MCM2-7 Form Double Hexamers at Licensed Origins in Xenopus Egg Extract

    Gambus, A., Khoudoli, G. A., Jones, R. C. & Blow, J. J. 1 Apr 2011 In : Journal of Biological Chemistry. 286, 13, p. 11855-11864 10 p.

    Research output: Contribution to journalArticle

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