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  1. Mutagenic analysis of the intracellular portals of the human 5-HT3A receptor

    Carland, J. E., Cooper, M. A., Livesey, M. R., Hales, T. G., Lambert, J. J. & Peters, J. A. 1 Nov 2013 In : Journal of Biological Chemistry. 288, 44, p. 31592-31601 10 p.

    Research output: Contribution to journalArticle

  2. The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing

    Caillat, C., Pefani, D-E., Gillespie, P. J., Taraviras, S., Blow, J. J., Lygerou, Z. & Perrakis, A. Nov 2013 In : Journal of Biological Chemistry. 288, 44, p. 31624-31634 11 p.

    Research output: Contribution to journalArticle

  3. The minimum M3-M4 loop length of neurotransmitteractivated pentameric receptors is critical for the structural integrity of cytoplasmic portals

    Baptista-Hon, D. T., Deeb, T. Z., Lambert, J. J., Peters, J. A. & Hales, T. G. 26 Jul 2013 In : Journal of Biological Chemistry. 288, 30, p. 21558-21568 11 p.

    Research output: Contribution to journalArticle

  4. The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow

    Lek, H. S., Morrison, V. L., Conneely, M., Campbell, P. A., McGloin, D., Kliche, S., Watts, C., Prescott, A. & Fagerholm, S. C. 24 May 2013 In : Journal of Biological Chemistry. 288, 21, p. 14698-14708 11 p.

    Research output: Contribution to journalArticle

  5. A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle

    Wypijewski, K. J., Howie, J., Reilly, L., Tulloch, L. B., Aughton, K. L., McLatchie, L. M., Shattock, M. J., Calaghan, S. C. & Fuller, W. 10 May 2013 In : Journal of Biological Chemistry. 288, 19, p. 13808-13820 13 p.

    Research output: Contribution to journalArticle

  6. Structure of a complex phosphoglycan epitope from gp72 of Trypanosoma cruzi

    Allen, S., Richardson, J. M., Mehlert, A. & Ferguson, M. A. J. 19 Apr 2013 In : Journal of Biological Chemistry. 288, 16, p. 11093-11105 13 p.

    Research output: Contribution to journalArticle

  7. Ca2+ signalling through CatSper and Ca2+ stores regulate different behaviours in human sperm

    Alasmari, W., Costello, S., Correia, J., Oxenham, S. K., Morris, J., Fernandes, L., Ramalho Santos, J., Kirkman-Brown, J., Michelangeli, F., Publicover, S. & Barratt, C. L. R. 1 Mar 2013 In : Journal of Biological Chemistry. 288, 9, p. 6248-6258 11 p.

    Research output: Contribution to journalArticle

  8. Dual regulation of Glycogen Synthase Kinase 3 (GSK3)alpha/beta by Protein Kinase C (PKC)alpha and Akt promotes Thrombin-mediated Integrin alpha(IIb)beta(3) activation and granule secretion in platelets

    Moore, S. F., van den Bosch, M. T. J., Hunter, R. W., Sakamoto, K., Poole, A. W. & Hers, I. 2013 In : Journal of Biological Chemistry. 288, 6, p. 3918-3928 11 p.

    Research output: Contribution to journalArticle

  9. N-terminal serine dephosphorylation is required for KCC3 cotransporter full activation by cell swelling

    Melo, Z., De Los Heros, P., Cruz-Rangel, S., Vázquez, N., Bobadilla, N. A., Pasantes-Morales, H., Alessi, D. R., Mercado, A. & Gamba, G. 2013 In : Journal of Biological Chemistry. 288, 44, p. 31468-31476 9 p.

    Research output: Contribution to journalArticle

  10. The involvement of mitochondrial amidoxime reducing components 1 and 2 and mitochondrial cytochrome b5 in N-reductive metabolism in human cells

    Plitzko, B., Ott, G., Reichmann, D., Henderson, C. J., Wolf, C. R., Mendel, R., Bittner, F., Clement, B. & Havemeyer, A. 2013 In : Journal of Biological Chemistry. 288, 28, p. 20228-20237 10 p.

    Research output: Contribution to journalArticle

  11. Family with Sequence Similarity 60A (FAM60A) Protein Is a Cell Cycle-fluctuating Regulator of the SIN3-HDAC1 Histone Deacetylase Complex

    Munoz, I. M., Macartney, T., Sanchez-Pulido, L., Ponting, C. P., Rocha, S. & Rouse, J. 21 Sep 2012 In : Journal of Biological Chemistry. 287, 39, p. 32346-53 8 p.

    Research output: Contribution to journalArticle

  12. Monoubiquitination Promotes Calpain Cleavage of the Protein Phosphatase 2A (PP2A) Regulatory Subunit alpha 4, Altering PP2A Stability and Microtubule-associated Protein Phosphorylation

    Watkins, G. R., Wang, N., Mazalouskas, M. D., Gomez, R. J., Guthrie, C. R., Kraemer, B. C., Schweiger, S., Spiller, B. W. & Wadzinski, B. E. 13 Jul 2012 In : Journal of Biological Chemistry. 287, 29, p. 24207-24215 9 p.

    Research output: Contribution to journalArticle

  13. A conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome

    Kilkenny, M. L., De Piccoli, G., Perera, R. L., Labib, K. & Pellegrini, L. 6 Jul 2012 In : Journal of Biological Chemistry. 287, 28, p. 23740-23747 8 p.

    Research output: Contribution to journalArticle

  14. IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold

    Dixon, M. J., Gray, A., Schenning, M., Agacan, M., Tempel, W., Tong, Y., Nedyalkova, L., Park, H-W., Leslie, N. R., van Aalten, D. M. F., Downes, C. P. & Batty, I. H. 29 Jun 2012 In : Journal of Biological Chemistry. 287, 27, p. 22483-22496 14 p.

    Research output: Contribution to journalArticle

  15. Defining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cells

    Turban, S., Stretton, C., Drouin, O., Green, C. J., Watson, M. L., Gray, A., Ross, F., Lantier, L., Viollet, B., Hardie, D. G., Marette, A. & Hundal, H. S. 8 Jun 2012 In : Journal of Biological Chemistry. 287, 24, p. 20088-20099 12 p.

    Research output: Contribution to journalArticle

  16. Essential Role for IKK beta in Production of Type 1 Interferons by Plasmacytoid Dendritic Cells

    Pauls, E., Shpiro, N., Peggie, M., Young, E. R., Sorcek, R. J., Tan, L., Choi, H. G. & Cohen, P. 1 Jun 2012 In : Journal of Biological Chemistry. 287, 23, p. 19216-19228 13 p.

    Research output: Contribution to journalArticle

  17. Escherichia coli TatA and TatB Proteins Have N-out, C-in Topology in Intact Cells

    Koch, S., Fritsch, M. J., Buchanan, G. & Palmer, T. 27 Apr 2012 In : Journal of Biological Chemistry. 287, 18, p. 14420-14431 12 p.

    Research output: Contribution to journalArticle

  18. Distinct control of MyD88 adapter-dependent and Akt kinase-regulated responses by the interleukin (IL)-1RI co-receptor, TILRR

    Zhang, X., Montagut Pino, G., Shephard, F., Kiss-Toth, E. & Qwarnstrom, E. E. 6 Apr 2012 In : Journal of Biological Chemistry. 287, 15, p. 12348-12352 5 p.

    Research output: Contribution to journalArticle

  19. Phosphorylation of FOXO3a on Ser-7 by p38 promotes its nuclear localization in response to doxorubicin

    Ho, K-K., McGuire, V. A., Koo, C-Y., Muir, K. W., de Olano, N., Maifoshie, E., Kelly, D. J., McGovern, U. B., Monteiro, L. J., Gomes, A. R., Nebreda, A. R., Campbell, D. G., Arthur, J. S. C. & Lam, E. W. -F. 6 Jan 2012 In : Journal of Biological Chemistry. 287, 2, p. 1545-1555 11 p.

    Research output: Contribution to journalArticle

  20. Modulation of L-alpha-Lysophosphatidylinositol/GPR55 Mitogen-activated Protein Kinase (MAPK) Signaling by Cannabinoids

    Anavi-Goffer, S., Baillie, G., Irving, A. J., Gertsch, J., Greig, I. R., Pertwee, R. G. & Ross, R. A. 2 Jan 2012 In : Journal of Biological Chemistry. 287, 1, p. 91-104 14 p.

    Research output: Contribution to journalArticle

  21. Avirulence protein 3a (AVR3a) from the potato pathogen Phytophthora infestans forms homodimers through its predicted translocation region and does not specifically bind phospholipids

    Wawra, S., Agacan, M., Boddey, J. A., Davidson, I., Gachon, C. M. M., Zanda, M., Grouffaud, S., Whisson, S. C., Birch, P. R. J., Porter, A. J. & Van West, P. 2012 In : Journal of Biological Chemistry. 287, 45, p. 38101-38109 9 p.

    Research output: Contribution to journalArticle

  22. Pellino1 Is Required for Interferon Production by Viral Double-stranded RNA

    Enesa, K., Ordureau, A., Smith, H., Barford, D., Cheung, P. C. F., Patterson-Kane, J., Arthur, J. S. C. & Cohen, P. 2012 In : Journal of Biological Chemistry. 287, 41, p. 34825-34835 11 p.

    Research output: Contribution to journalArticle

  23. Role of binding and nucleoside diphosphate kinase A in the regulation of the cystic fibrosis transmembrane conductance regulator by AMP-activated protein kinase

    King, J. D., Lee, J., Riemen, C. E., Neumann, D., Xiong, S., Foskett, J. K., Mehta, A., Muimo, R. & Hallows, K. R. 2012 In : Journal of Biological Chemistry. 287, 40, p. 33389-33400 12 p.

    Research output: Contribution to journalArticle

  24. Transforming Growth Factor-β directly induces PUMA during the rapid induction of apoptosis in Myc-driven B-cell lymphomas.

    Spender, L. C., Carter, M. J., O'Brien, D. I., Clark, L. J., Yu, J., Michalak, E. M., Happo, L., Cragg, M. S. & Inman, G. J. 2012 In : Journal of Biological Chemistry.

    Research output: Contribution to journalArticle

  25. Distinct Docking Mechanisms Mediate Interactions between the Msg5 Phosphatase and Mating or Cell Integrity Mitogen-activated Protein Kinases (MAPKs) in Saccharomyces cerevisiae

    Palacios, L., Dickinson, R. J., Sacristan-Reviriego, A., Didmon, M. P., Jose Marin, M., Martin, H., Keyse, S. M. & Molina, M. 9 Dec 2011 In : Journal of Biological Chemistry. 286, 49, p. 42037-42050 14 p.

    Research output: Contribution to journalArticle

  26. Internalization of Exogenous Cystatin F Supresses Cysteine Proteases and Induces the Accumulation of Single-chain Cathepsin L by Multiple Mechanisms

    Colbert, J. D., Matthews, S. P., Kos, J. & Watts, C. 9 Dec 2011 In : Journal of Biological Chemistry. 286, 49, p. 42082-42090 9 p.

    Research output: Contribution to journalArticle

  27. Chemical structure of Trichomonas vaginalis surface lipoglycan: a role for short galactose (beta 1-4/3) N-acetylglucosamine repeats in host cell interaction

    Ryan, C. M., Mehlert, A., Richardson, J. M., Ferguson, M. A. J. & Johnson, P. J. 25 Nov 2011 In : Journal of Biological Chemistry. 286, 47, p. 40494-40508 15 p.

    Research output: Contribution to journalArticle

  28. Protein Phosphatase 2A (PP2A)-specific Ubiquitin Ligase MID1 Is a Sequence-dependent Regulator of Translation Efficiency Controlling 3-Phosphoinositide-dependent Protein Kinase-1 (PDPK-1)

    Aranda-Orgilles, B., Rutschow, D., Zeller, R., Karagiannidis, A. I., Koehler, A., Chen, C., Wilson, T., Krause, S., Roepcke, S., Lilley, D., Schneider, R. & Schweiger, S. 18 Nov 2011 In : Journal of Biological Chemistry. 286, 46, p. 39945-39957 13 p.

    Research output: Contribution to journalArticle

  29. Phosphorylation of the Kinase Interaction Motif in Mitogen-activated Protein (MAP) Kinase Phosphatase-4 Mediates Cross-talk between Protein Kinase A and MAP Kinase Signaling Pathways

    Dickinson, R. J., Delavaine, L., Cejudo-Marin, R., Stewart, G., Staples, C. J., Didmon, M. P., Garcia Trinidad, A., Alonso, A., Pulido, R. & Keyse, S. M. 4 Nov 2011 In : Journal of Biological Chemistry. 286, 44, p. 38018-38026 9 p.

    Research output: Contribution to journalArticle

  30. Polyubiquitin Binding to Optineurin Is Required for Optimal Activation of TANK-binding Kinase 1 and Production of Interferon beta

    Gleason, C. E., Ordureau, A., Gourlay, R., Arthur, J. S. C. & Cohen, P. 14 Oct 2011 In : Journal of Biological Chemistry. 286, 41, p. 35663-35674 12 p.

    Research output: Contribution to journalArticle

  31. The inhibitory effect of phospholemman on the sodium pump requires Its palmitoylation

    Tulloch, L. B., Howie, J., Wypijewski, K. J., Wilson, C. R., Bernard, W. G., Shattock, M. J. & Fuller, W. 14 Oct 2011 In : Journal of Biological Chemistry. 286, 41, p. 36020-36031 12 p.

    Research output: Contribution to journalArticle

  32. Early murine T-lymphocyte activation is accompanied by a switch from N-glycolyl- to N-acetyl-neuraminic acid and generation of ligands for siglec-E

    Redelinghuys, P., Antonopoulos, A., Liu, Y., Campanero-Rhodes, M. A., McKenzie, E., Haslam, S. M., Dell, A., Feizi, T. & Crocker, P. R. 7 Oct 2011 In : Journal of Biological Chemistry. 286, 40, p. 34522-34532 11 p.

    Research output: Contribution to journalArticle

  33. Structural analysis of human FANCL, the E3 ligase in the Fanconi anemia pathway

    Hodson, C., Cole, A. R., Lewis, L. P. C., Miles, J. A., Purkiss, A. & Walden, H. 16 Sep 2011 In : Journal of Biological Chemistry. 286, 37, p. 32628-32637 10 p.

    Research output: Contribution to journalArticle

  34. Low Resolution Structure of a Bacterial SLC26 Transporter Reveals Dimeric Stoichiometry and Mobile Intracellular Domains

    Compton, E. L. R., Karinou, E., Naismith, J. H., Gabel, F. & Javelle, A. 29 Jul 2011 In : Journal of Biological Chemistry. 286, 30, p. 27058-27067 10 p.

    Research output: Contribution to journalArticle

  35. Bioinformatic Prediction and Confirmation of beta-Adducin as a Novel Substrate of Glycogen Synthase Kinase 3

    Farghaian, H., Turnley, A. M., Sutherland, C. & Cole, A. R. 15 Jul 2011 In : Journal of Biological Chemistry. 286, 28, p. 25274-25283 10 p.

    Research output: Contribution to journalArticle

  36. Identification of a Proline-rich Inositol Polyphosphate 5-Phosphatase (PIPP)center dot Collapsin Response Mediator Protein 2 (CRMP2) Complex That Regulates Neurite Elongation

    Astle, M. V., Ooms, L. M., Cole, A. R., Binge, L. C., Dyson, J. M., Layton, M. J., Petratos, S., Sutherland, C. & Mitchell, C. A. 1 Jul 2011 In : Journal of Biological Chemistry. 286, 26, p. 23407-23418 12 p.

    Research output: Contribution to journalArticle

  37. A Systemic Lupus Erythematosus-associated R77H Substitution in the CD11b Chain of the Mac-1 Integrin Compromises Leukocyte Adhesion and Phagocytosis

    MacPherson, M., Lek, H. S., Prescott, A. & Fagerholm, S. C. 13 May 2011 In : Journal of Biological Chemistry. 286, 19, p. 17303-17310 8 p.

    Research output: Contribution to journalArticle

  38. Rings of Charge within the Extracellular Vestibule Influence Ion Permeation of the 5-HT(3)A Receptor

    Livesey, M. R., Cooper, M. A., Lambert, J. J. & Peters, J. A. 6 May 2011 In : Journal of Biological Chemistry. 286, 18, p. 16008-16017 10 p.

    Research output: Contribution to journalArticle

  39. A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1

    Narayan, V., Halada, P., Hernychová, L., Chong, Y. P., Žáková, J., Hupp, T. R., Vojtesek, B. & Ball, K. L. 22 Apr 2011 In : Journal of Biological Chemistry. 286, 16, p. 14291-14303 13 p.

    Research output: Contribution to journalArticle

  40. Selective Expression in Carotid Body Type I Cells of a Single Splice Variant of the Large Conductance Calcium- and Voltage-activated Potassium Channel Confers Regulation by AMP-activated Protein Kinase

    Ross, F. A., Rafferty, J. N., Dallas, M. L., Ogunbayo, O., Ikematsu, N., McClafferty, H., Tian, L., Widmer, H., Rowe, I. C. M., Wyatt, C. N., Shipston, M. J., Peers, C., Hardie, D. G. & Evans, A. M. 8 Apr 2011 In : Journal of Biological Chemistry. 286, 14, p. 11929-11936 8 p.

    Research output: Contribution to journalArticle

  41. MCM2-7 Form Double Hexamers at Licensed Origins in Xenopus Egg Extract

    Gambus, A., Khoudoli, G. A., Jones, R. C. & Blow, J. J. 1 Apr 2011 In : Journal of Biological Chemistry. 286, 13, p. 11855-11864 10 p.

    Research output: Contribution to journalArticle

  42. Dissecting the Metabolic Roles of Pteridine Reductase 1 in Trypanosoma brucei and Leishmania major

    Ong, H. B., Sienkiewicz, N., Wyllie, S. & Fairlamb, A. H. 25 Mar 2011 In : Journal of Biological Chemistry. 286, 12, p. 10429-10438 10 p.

    Research output: Contribution to journalArticle

  43. Antitumor Quinol PMX464 Is a Cytocidal Anti-trypanosomal Inhibitor Targeting Trypanothione Metabolism

    Konig, J., Wyllie, S., Wells, G., Stevens, M. F., Wyatt, P. G. & Fairlamb, A. H. 11 Mar 2011 In : Journal of Biological Chemistry. 286, 10, p. 8523-8533 11 p.

    Research output: Contribution to journalArticle

  44. Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway

    Deleris, P., Trost, M., Topisirovic, I., Tanguay, P-L., Borden, K. L. B., Thibault, P. & Meloche, S. 25 Feb 2011 In : Journal of Biological Chemistry. 286, 8, p. 6470-6478 9 p.

    Research output: Contribution to journalArticle

  45. Cooperative Binding and Activation of Fibronectin by a Bacterial Surface Protein

    Marjenberg, Z. R., Ellis, I. R., Hagan, R. M., Prabhakaran, S., Hoeoek, M., Talay, S. R., Potts, J. R., Staunton, D. & Schwarz-Linek, U. 21 Jan 2011 In : Journal of Biological Chemistry. 286, 3, p. 1884-1894 11 p.

    Research output: Contribution to journalArticle

  46. Docking-dependent ubiquitination of the interferon regulatory factor-1 tumor suppressor protein by the ubiquitin ligase CHIP

    Narayan, V., Pion, E., Landré, V., Müller, P. & Ball, K. L. 7 Jan 2011 In : Journal of Biological Chemistry. 286, 1, p. 607-619 13 p.

    Research output: Contribution to journalArticle

  47. Functional dissection of Adenylate Cyclase R, an inducer of spore encapsulation

    Chen, Z., Schilde, C. & Schaap, P. 31 Dec 2010 In : Journal of Biological Chemistry. 285, 53, p. 41724-41731 8 p.

    Research output: Contribution to journalArticle

  48. Intracellular activation of interferon regulatory factor-1 by nanobodies to the multifunctional (Mf1) domain

    Möller, A., Pion, E., Narayan, V. & Ball, K. L. 3 Dec 2010 In : Journal of Biological Chemistry. 285, 49, p. 38348-38361 14 p.

    Research output: Contribution to journalArticle

  49. Evolution and Multiplicity of Arginine Decarboxylases in Polyamine Biosynthesis and Essential Role in Bacillus subtilis Biofilm Formation

    Burrell, M., Hanfrey, C. C., Murray, E. J., Stanley-Wall, N. R. & Michael, A. J. Dec 2010 In : Journal of Biological Chemistry. 285, 50, p. 39224-39238 15 p.

    Research output: Contribution to journalArticle

  50. Identification of key functional residues in the active site of human beta 1, 4-Galactosyltransferase 7: a major enzyme in the glycosaminoglycan synthesis pathway

    Talhaoui, I., Bui, C., Oriol, R., Mulliert, G., Gulberti, S., Netter, P., Coughtrie, M. W. H., Ouzzine, M. & Fournel-Gigleux, S. 26 Nov 2010 In : Journal of Biological Chemistry. 285, 48, p. 37342-37358 17 p.

    Research output: Contribution to journalArticle

  51. An Exceptionally Potent Inducer of Cytoprotective Enzymes elucidation of the structural features that determine inducer potency and reactivity with Keap1

    Dinkova-Kostova, A. T., Talalay, P., Sharkey, J., Zhang, Y., Holtzclaw, W. D., Wang, X. J., David, E., Schiavoni, K. H., Finlayson, S., Mierke, D. F. & Honda, T. 29 Oct 2010 In : Journal of Biological Chemistry. 285, 44, p. 33747-33755 9 p.

    Research output: Contribution to journalArticle

  52. Cot/tpl2 (MAP3K8) Mediates Myeloperoxidase Activity and Hypernociception following Peripheral Inflammation

    Soria-Castro, I., Krzyzanowska, A., Pelaéz, M. L., Regadera, J., Ferrer, G., Montoliu, L., Rodríguez-Ramos, R., Fernández, M. & Alemany, S. 29 Oct 2010 In : Journal of Biological Chemistry. 285, 44, p. 33805-33815 11 p.

    Research output: Contribution to journalArticle

  53. RIC-3 Exclusively Enhances the Surface Expression of Human Homomeric 5-Hydroxytryptamine Type 3A (5-HT(3)A) Receptors Despite Direct Interactions with 5-HT3A, -C, -D, and -E Subunits

    Walstab, J., Hammer, C., Lasitschka, F., Moeller, D., Connolly, C. N., Rappold, G., Bruess, M., Boenish, H. & Niesler, B. 27 Aug 2010 In : Journal of Biological Chemistry. 285, 35, p. 26956-26965 10 p.

    Research output: Contribution to journalArticle

  54. Cross-talk between the p38 alpha and JNK MAPK Pathways Mediated by MAP Kinase Phosphatase-1 Determines Cellular Sensitivity to UV Radiation

    Staples, C. J., Owens, D. M., Maier, J. V., Cato, A. C. B. & Keyse, S. M. 20 Aug 2010 In : Journal of Biological Chemistry. 285, 34, p. 25928-25940 13 p.

    Research output: Contribution to journalArticle

  55. Two novel Src homology 2 domain proteins interact to regulate Dictyostelium gene expression during growth and early development

    Sugden, C., Ross, S., Bloomfield, G., Ivens, A., Skelton, J., Mueller-Taubenberger, A. & Williams, J. G. 23 Jul 2010 In : Journal of Biological Chemistry. 285, 30, p. 22927-22935 9 p.

    Research output: Contribution to journalArticle

  56. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription

    Jain, A., Lamark, T., Sjottem, E., Larsen, K. B., Awuh, J. A., Overvatn, A., McMahon, M., Hayes, J. D. & Johansen, T. 16 Jul 2010 In : Journal of Biological Chemistry. 285, 29, p. 22576-22591 16 p.

    Research output: Contribution to journalArticle

  57. Nuclear DBF-2-related Kinases Are Essential Regulators of Cytokinesis in Bloodstream Stage Trypanosoma brucei

    Ma, J., Benz, C., Grimaldi, R., Stockdale, C., Wyatt, P., Frearson, J. & Hammarton, T. C. 14 May 2010 In : Journal of Biological Chemistry. 285, 20, p. 15356-15368 13 p.

    Research output: Contribution to journalArticle

  58. Ubiquitination of PTEN (Phosphatase and Tensin Homolog) Inhibits Phosphatase Activity and Is Enhanced by Membrane Targeting and Hyperosmotic Stress

    Maccario, H., Perera, N. M., Gray, A., Downes, C. P. & Leslie, N. R. 23 Apr 2010 In : Journal of Biological Chemistry. 285, 17, p. 12620-12628 9 p.

    Research output: Contribution to journalArticle

  59. The Snf2 Homolog Fun30 acts as a homodimeric ATP-dependent chromatin-remodeling enzyme

    Awad, S., Ryan, D., Prochasson, P., Owen-Hughes, T. & Hassan, A. H. 26 Mar 2010 In : Journal of Biological Chemistry. 285, 13, p. 9477-9484 8 p.

    Research output: Contribution to journalArticle

  60. How Escherichia coli is equipped to oxidize hydrogen under different redox conditions

    Lukey, M. J., Parkin, A., Roessler, M. M., Murphy, B. J., Harmer, J., Armstrong, F. A., Palmer, T. & Sargent, F. 5 Feb 2010 In : Journal of Biological Chemistry. 285, 6, p. 3928-3938 11 p.

    Research output: Contribution to journalArticle

  61. Chemical Validation of Trypanothione Synthetase a potential drug targer for human trypanosomiasis

    Torrie, L. S., Wyllie, S., Spinks, D., Oza, S. L., Thompson, S., Harrison, J. R., Gilbert, I. H., Wyatt, P. G., Fairlamb, A. H. & Frearson, J. A. 25 Dec 2009 In : Journal of Biological Chemistry. 284, 52, p. 36137-36145 9 p.

    Research output: Contribution to journalArticle

  62. Identification of a novel family of laminin N-terminal alternate splice isoforms structural and functional characterization

    Hamill, K. J., Langbein, L., Jones, J. C. R. & McLean, W. H. I. 18 Dec 2009 In : Journal of Biological Chemistry. 284, 51, p. 35588-35596 9 p.

    Research output: Contribution to journalArticle

  63. CK1 alpha Plays a Central Role in Mediating MDM2 Control of p53 and E2F-1 Protein Stability

    Huart, A-S., MacLaine, N. J., Meek, D. W. & Hupp, T. R. 20 Nov 2009 In : Journal of Biological Chemistry. 284, 47, p. 32384-32394 11 p.

    Research output: Contribution to journalArticle

  64. Blom7 alpha Is a Novel Heterogeneous Nuclear Ribonucleoprotein K Homology Domain Protein Involved in Pre-mRNA Splicing That Interacts with SNEVPrp19-Pso4

    Grillari, J., Loescher, M., Denegri, M., Lee, K., Fortschegger, K., Eisenhaber, F., Ajuh, P., Lamond, A. I., Katinger, H. & Grillari-Voglauer, R. 16 Oct 2009 In : Journal of Biological Chemistry. 284, 42, p. 29193-29204 12 p.

    Research output: Contribution to journalArticle

  65. Cooperative regulation of the interferon regulatory factor-1 tumor suppressor protein by core components of the molecular chaperone machinery

    Narayan, V., Eckert, M., Zylicz, A., Zylicz, M. & Ball, K. L. 18 Sep 2009 In : Journal of Biological Chemistry. 284, 38, p. 25889-25899 11 p.

    Research output: Contribution to journalArticle

  66. ABC50 promotes translation initiation in mammalian cells

    Paytubi, S., Wang, X., Lam, Y. W., Izquierdo, L., Hunter, M. J., Jan, E., Hundal, H. S. & Proud, C. G. 4 Sep 2009 In : Journal of Biological Chemistry. 284, 36, p. 24061-24073 13 p.

    Research output: Contribution to journalArticle

  67. Keep Nibbling at the Edges

    Cohen, P. 4 Sep 2009 In : Journal of Biological Chemistry. 284, 36, p. 23891-23901 11 p.

    Research output: Contribution to journalEditorial

  68. Phosphorylation of histone H3 Thr-45 is linked to apoptosis

    Hurd, P. J., Bannister, A. J., Halls, K., Dawson, M. A., Vermeulen, M., Olsen, J. V., Ismail, H., Somers, J., Mann, M., Owen-Hughes, T., Gout, I. & Kouzarides, T. 12 Jun 2009 In : Journal of Biological Chemistry. 284, 24, p. 16575-16583 9 p.

    Research output: Contribution to journalArticle

  69. Angiotensin-converting enzyme Ii a modifier of hypertensive end organ damage

    Liu, X., Bellamy, C. O. C., Bailey, M. A., Mullins, L. J., Dunbar, D. R., Kenyon, C. J., Brooker, G., Kantachuvesiri, S., Maratou, K., Ashek, A., Clark, A. F., Fleming, S. & Mullins, J. J. 5 Jun 2009 In : Journal of Biological Chemistry. 284, 23, p. 15564-15572 9 p.

    Research output: Contribution to journalArticle

  70. Motogenic Sites in Human Fibronectin Are Masked by Long Range Interactions

    Vakonakis, I., Staunton, D., Ellis, I. R., Sarkies, P., Flanagan, A., Schor, A. M., Schor, S. L. & Campbell, I. D. 5 Jun 2009 In : Journal of Biological Chemistry. 284, 23, p. 15668-15675 8 p.

    Research output: Contribution to journalArticle

  71. Structure-based ligand design and the promise held for antiprotozoan drug discovery

    Hunter, W. N. 1 May 2009 In : Journal of Biological Chemistry. 284, 18, p. 11749-11753 5 p.

    Research output: Contribution to journalScientific review

  72. ULK1 center dot ATG13 center dot FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

    Ganley, I. G., Lam, D. H., Wang, J., Ding, X., Chen, S. & Jiang, X. 1 May 2009 In : Journal of Biological Chemistry. 284, 18, p. 12297-12305 9 p.

    Research output: Contribution to journalArticle

  73. RIG-I-mediated activation of p38 MAPK is essential for viral induction of interferon and activation of dendritic cells: dependence on TRAF2 and TAK1

    Mikkelsen, S. S., Jensen, S. B., Chiliveru, S., Melchjorsen, J., Julkunen, I., Gaestel, M., Arthur, J. S. C., Flavell, R. A., Ghosh, S. & Paludan, S. R. 17 Apr 2009 In : Journal of Biological Chemistry. 284, 16, p. 10774-10782 9 p.

    Research output: Contribution to journalArticle

  74. Leptin-dependent Phosphorylation of PTEN Mediates Actin Restructuring and Activation of ATP-sensitive K+ Channels

    Ning, K., Miller, L. C., Laidlaw, H. A., Watterson, K. R., Gallagher, J., Sutherland, C. & Ashford, M. L. J. 3 Apr 2009 In : Journal of Biological Chemistry. 284, 14, p. 9331-9340 10 p.

    Research output: Contribution to journalArticle

  75. Molecular mechanisms of yeast cell wall glucan remodeling

    Hurtado-Guerrero, R., Schuettelkopf, A. W., Mouyna, I., Ibrahim, A. F. M., Shepherd, S., Fontaine, T., Latge, J-P. & van Aalten, D. M. F. 27 Mar 2009 In : Journal of Biological Chemistry. 284, 13, p. 8461-8469 9 p.

    Research output: Contribution to journalArticle

  76. Enhancing the receptor affinity of the sialic acid-binding domain of Vibrio cholerae sialidase through multivalency

    Connaris, H., Crocker, P. R. & Taylor, G. L. 13 Mar 2009 In : Journal of Biological Chemistry. 284, 11, p. 7339-7351 13 p.

    Research output: Contribution to journalArticle

  77. Basic Residues Are Critical to the Activity of Peptide Inhibitors of Human T Cell Leukemia Virus Type 1 Entry

    Lamb, D., Mirsaliotis, A., Kelly, S. M. & Brighty, D. W. 6 Mar 2009 In : Journal of Biological Chemistry. 284, 10, p. 6575-6584 10 p.

    Research output: Contribution to journalArticle

  78. Mechanistic Insight into Control of CFTR by AMPK

    Kongsuphol, P., Cassidy, D., Hieke, B., Treharne, K. J., Schreiber, R., Mehta, A. & Kunzelmann, K. 27 Feb 2009 In : Journal of Biological Chemistry. 284, 9, p. 5645-5653 9 p.

    Research output: Contribution to journalArticle

  79. Suppression of the Deubiquitinating Enzyme USP5 Causes the Accumulation of Unanchored Polyubiquitin and the Activation of p53

    Dayal, S., Sparks, A., Jacob, J., Allende-Vega, N., Lane, D. & Saville, M. K. 20 Feb 2009 In : Journal of Biological Chemistry. 284, 8, p. 5030-5041 12 p.

    Research output: Contribution to journalArticle

  80. SWI/SNF regulates the cellular response to hypoxia

    Kenneth, N. S., Mudie, S., van Uden, P. & Rocha, S. 13 Feb 2009 In : Journal of Biological Chemistry. 284, 7, p. 4123-4131 9 p.

    Research output: Contribution to journalArticle

  81. The Nrf3 transcription factor is a membrane-bound glycoprotein targeted to the endoplasmic reticulum through Its N-terminal Homology Box 1 Sequence

    Zhang, Y., Kobayashi, A., Yamamoto, M. & Hayes, J. D. 30 Jan 2009 In : Journal of Biological Chemistry. 284, 5, p. 3195-3210 16 p.

    Research output: Contribution to journalArticle

  82. Characterization of the Effects of Charged Residues in the Intracellular Loop on Ion Permeation in alpha 1 Glycine Receptor Channels

    Carland, J. E., Cooper, M. A., Sugiharto, S., Jeong, H-J., Lewis, T. M., Barry, P. H., Peters, J. A., Lambert, J. J. & Moorhouse, A. J. 23 Jan 2009 In : Journal of Biological Chemistry. 284, 4, p. 2023-2030 8 p.

    Research output: Contribution to journalArticle

  83. TGF-beta Induces Growth Arrest in Burkitt Lymphoma Cells via Transcriptional Repression of E2F-1

    Spender, L. C. & Inman, G. J. 16 Jan 2009 In : Journal of Biological Chemistry. 284, 3, p. 1435-1442 8 p.

    Research output: Contribution to journalArticle

  84. ABF1-binding sites promote efficient global genome nucleotide excision repair

    Yu, S., Smirnova, J. B., Friedberg, E. C., Stillman, B., Akiyama, M., Owen-Hughes, T., Waters, R. & Reed, S. H. 9 Jan 2009 In : Journal of Biological Chemistry. 284, 2, p. 966-973 8 p.

    Research output: Contribution to journalArticle

  85. C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest

    Fogarty, S. & Hardie, D. G. 2 Jan 2009 In : Journal of Biological Chemistry. 284, 1, p. 77-84 8 p.

    Research output: Contribution to journalArticle

  86. Docking of PRAK/MK5 to the atypical MAPKs ERK3 and ERK4 defines a novel MAPK interaction motif

    Aberg, E., Torgersen, K. M., Johansen, B., Keyse, S. M., Perander, M. & Seternes, O-M. 2009 In : Journal of Biological Chemistry. 284, 29, p. 19392-401 10 p.

    Research output: Contribution to journalArticle

  87. Protein Kinase C-mediated Phosphorylation and activation of PDE3A Regulate cAMP levels in human platelets

    Hunter, R., MacKintosh, C. & Hers, I. 2009 In : Journal of Biological Chemistry. 284, 18, p. 12339-12348 10 p.

    Research output: Contribution to journalArticle

  88. FANCJ Is a Structure-specific DNA Helicase Associated with the Maintenance of Genomic G/C Tracts

    London, T. B. C., Barber, L. J., Mosedale, G., Kelly, G. P., Balasubramanian, S., Hickson, I. D., Boulton, S. J. & Hiom, K. 26 Dec 2008 In : Journal of Biological Chemistry. 283, 52, p. 36132-36139 8 p.

    Research output: Contribution to journalArticle

  89. Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes

    Ohtsuji, M., Katsuoka, F., Kobayashi, A., Aburatani, H., Hayes, J. D. & Yamamoto, M. 28 Nov 2008 In : Journal of Biological Chemistry. 283, 48, p. 33554-33562 9 p.

    Research output: Contribution to journalArticle

  90. Defining the in Vivo Role for Cytochrome b(5) in Cytochrome P450 Function through the Conditional Hepatic Deletion of Microsomal Cytochrome b(5)

    Finn, R. D., McLaughlin, L. A., Ronseaux, S., Rosewell, I., Houston, J. B., Henderson, C. J. & Wolf, C. R. 14 Nov 2008 In : Journal of Biological Chemistry. 283, 46, p. 31385-31393 9 p.

    Research output: Contribution to journalArticle

  91. Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment

    Mace, P. D., Linke, K., Feltham, R., Schumacher, F-R., Smith, C. A., Vaux, D. L., Silke, J. & Day, C. L. 14 Nov 2008 In : Journal of Biological Chemistry. 283, 46, p. 31633-31640 8 p.

    Research output: Contribution to journalArticle

  92. A central role for CK1 in catalyzing phosphorylation of the p53 transactivation domain at serine 20 after HHV-6B viral infection

    MacLaine, N. J., Oster, B., Bundgaard, B., Fraser, J. A., Buckner, C., Lazo, P. A., Meek, D. W., Hoellsberg, P. & Hupp, T. R. 17 Oct 2008 In : Journal of Biological Chemistry. 283, 42, p. 28563-28573 11 p.

    Research output: Contribution to journalArticle

  93. Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake

    Green, C. J., Goransson, O., Kular, G. S., Leslie, N. R., Gray, A., Alessi, D. R., Sakamoto, K. & Hundal, H. S. 10 Oct 2008 In : Journal of Biological Chemistry. 283, 41, p. 27653-27667 15 p.

    Research output: Contribution to journalArticle

  94. DsbA plays a critical and multifaceted role in the production of secreted virulence factors by the phytopathogen Erwinia carotovora subsp atroseptica

    Coulthurst, S. J., Lilley, K. S., Hedley, P. E., Liu, H., Toth, I. K. & Salmond, G. P. C. 29 Aug 2008 In : Journal of Biological Chemistry. 283, 35, p. 23739-23753 15 p.

    Research output: Contribution to journalArticle

  95. Phosphatidylethanolamine in Trypanosoma brucei is organized in two separate pools and is synthesized exclusively by the Kennedy pathway

    Signorell, A., Rauch, M., Jelk, J., Ferguson, M. A. J. & Buetikofer, P. 29 Aug 2008 In : Journal of Biological Chemistry. 283, 35, p. 23636-23644 9 p.

    Research output: Contribution to journalArticle

  96. Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor

    Livesey, M. R., Cooper, M. A., Deeb, T. Z., Carland, J. E., Kozuska, J., Hales, T. G., Lambert, J. J. & Peters, J. A. 11 Jul 2008 In : Journal of Biological Chemistry. 283, 28, p. 19301-19313 13 p.

    Research output: Contribution to journalArticle

  97. The scaffold MyD88 acts to couple protein kinase C epsilon to toll-like receptors

    Faisal, A., Saurin, A., Gregory, B., Foxwell, B. & Parker, P. J. 4 Jul 2008 In : Journal of Biological Chemistry. 283, 27, p. 18591-18600 10 p.

    Research output: Contribution to journalArticle

  98. Elevated levels of oncogenic protein kinase pim-1 induce the p53 pathway in cultured cells and correlate with increased mdm2 in mantle cell lymphoma

    Hogan, C., Hutchison, C., Marcar, L., Milne, D., Saville, M., Goodlad, J., Kernohan, N. & Meek, D. 27 Jun 2008 In : Journal of Biological Chemistry. 283, 26, p. 18012-18023 12 p.

    Research output: Contribution to journalArticle

  99. Relative resistance of Cdk5-phosphorylated CRMP2 to dephosphorylation

    Cole, A. R., Soutar, M. P. M., Rembutsu, M., van Aalten, L., Hastie, C. J., Mclauchlan, H., Peggie, M., Balastik, M., Lu, K. P. & Sutherland, C. 27 Jun 2008 In : Journal of Biological Chemistry. 283, 26, p. 18227-18237 11 p.

    Research output: Contribution to journalArticle

  100. A common theme in interaction of bacterial immunoglobulin-binding proteins with immunoglobulins illustrated in the equine system

    Lewis, M. J., Meehan, M., Owen, P. & Woof, J. M. 20 Jun 2008 In : Journal of Biological Chemistry. 283, 25, p. 17615-17623 9 p.

    Research output: Contribution to journalArticle

  101. Leishmania trypanothione synthetase-amidase structure reveals a basis for regulation of conflicting synthetic and hydrolytic activities

    Fyfe, P. K., Oza, S. L., Fairlamb, A. H. & Hunter, W. N. 20 Jun 2008 In : Journal of Biological Chemistry. 283, 25, p. 17672-17680 9 p.

    Research output: Contribution to journalArticle

  102. The synthesis of UDP-N-acetylglucosamine is essential for bloodstream form Trypanosoma brucei in vitro and in vivo and UDP-N-acetylglucosamine starvation reveals a hierarchy in parasite protein glycosylation

    Stokes, M. J., Guther, M. L. S., Turnock, D. C., Prescott, A. R., Martin, K. L., Alphey, M. S. & Ferguson, M. A. J. 6 Jun 2008 In : Journal of Biological Chemistry. 283, 23, p. 16147-16161 15 p.

    Research output: Contribution to journalArticle

  103. The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior

    Lee, H., Cho, J. S., Lambacher, N., Lee, J., Lee, S-J., Lee, T. H., Gartner, A. & Koo, H-S. 30 May 2008 In : Journal of Biological Chemistry. 283, 22, p. 14988-14993 6 p.

    Research output: Contribution to journalArticle

  104. Regulation of the epithelial Na+ channel by the protein kinase CK2

    Bachhuber, T., Almaca, J., Aldehni, F., Mehta, A., Amaral, M. D., Schreiber, R. & Kunzelmann, K. 9 May 2008 In : Journal of Biological Chemistry. 283, 19, p. 13225-13232 8 p.

    Research output: Contribution to journalArticle

  105. The docking interaction of caspase-9 with ERK2 provides a mechanism for the selective inhibitory phosphorylation of caspase-9 at threonine 125

    Martin, M. C., Allan, L. A., Mancini, E. J. & Clarke, P. R. 15 Feb 2008 In : Journal of Biological Chemistry. 283, 7, p. 3854-3865 12 p.

    Research output: Contribution to journalArticle

  106. Rosiglitazone stimulates nitric oxide synthesis in human aortic endothelial cells via AMP-activated protein kinase

    Boyle, J. G., Logan, P. J., Ewart, M-A., Reihill, J. A., Ritchie, S. A., Connell, J. M. C., Cleland, S. J. & Salt, I. P. 2008 In : Journal of Biological Chemistry. 283, 17, p. 11210-11217 8 p.

    Research output: Contribution to journalArticle

  107. The PSF.p54nrb complex is a novel Mnk substrate that binds the mRNA for tumor necrosis factor alpha

    Buxadé, M., Morrice, N., Krebs, D. L. & Proud, C. G. 2008 In : Journal of Biological Chemistry. 283, 1, p. 57-65 9 p.

    Research output: Contribution to journalArticle

  108. Resistance to neutralization by antibodies targeting the coiled coil of fusion-active envelope is a common feature of retroviruses

    Mirsaliotis, A., Nurkiyanova, K., Lamb, D., Kuo, C-W. S. & Brighty, D. W. 14 Dec 2007 In : Journal of Biological Chemistry. 282, 50, p. 36724-36735 12 p.

    Research output: Contribution to journalArticle

  109. Differential subcellular localization of RIC-3 Isoforms and their role in determining 5-HT3 receptor composition

    Cheng, A., Bollan, K. A., Greenwood, S. M., Irving, A. J. & Connolly, C. N. 7 Sep 2007 In : Journal of Biological Chemistry. 282, 36, p. 26158-26166 9 p.

    Research output: Contribution to journalArticle

  110. Mitochondrial dysfunction and dendritic beading during neuronal toxicity

    Greenwood, S. M., Mizielinska, S. M., Frenguelli, B. G., Harvey, J. & Connolly, C. N. 7 Sep 2007 In : Journal of Biological Chemistry. 282, 36, p. 26235-26244 10 p.

    Research output: Contribution to journalArticle

  111. The de novo synthesis of GDP-fucose is essential for flagellar adhesion and cell growth in trypanosoma brucei

    Turnock, D. C., Izquierdo, L. & Ferguson, M. A. J. Sep 2007 In : Journal of Biological Chemistry. 282, 39, p. 28853-28863 11 p.

    Research output: Contribution to journalArticle

  112. PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex

    Fonseca, B. D., Smith, E. M., Lee, V. H. -Y., MacKintosh, C. & Proud, C. G. 24 Aug 2007 In : Journal of Biological Chemistry. 282, 34, p. 24514-24524 11 p.

    Research output: Contribution to journalArticle

  113. Distinct sensor pathways in the hierarchical control of SNAT2, a putative amino acid transceptor, by amino acid availability

    Hyde, R., Cwiklinski, E. L., MacAulay, K., Taylor, P. M. & Hundal, H. S. 6 Jul 2007 In : Journal of Biological Chemistry. 282, 27, p. 19788-19798 11 p.

    Research output: Contribution to journalArticle

  114. Hypoxia-inducible factor 1α is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif

    Land, S. C. & Tee, A. R. Jul 2007 In : Journal of Biological Chemistry. 282, 28, p. 20534-20543 10 p.

    Research output: Contribution to journalArticle

  115. ZnT5 variant B is a bidirectional zinc transporter and mediates zinc uptake in human intestinal Caco-2 cells

    Valentine, R. A., Jackson, K. A., Christie, G. R., Mathers, J. C., Taylor, P. M. & Ford, D. 11 May 2007 In : Journal of Biological Chemistry. 282, 19, p. 14389-14393 5 p.

    Research output: Contribution to journalArticle

  116. Dynamic modification of a mutant cytoplasmic cysteine residue modulates the conductance of the human 5-HT3A receptor

    Deeb, T. Z., Carland, J. E., Cooper, M. A., Livesey, M. R., Lambert, J. J., Peters, J. A. & Hales, T. G. Mar 2007 In : Journal of Biological Chemistry. 282, 9, p. 6172-6182 11 p.

    Research output: Contribution to journalArticle

  117. Phosphorylation of the LFA-1 integrin beta2-chain on Thr-758 leads to adhesion, Rac-1/Cdc42 activation, and stimulation of CD69 expression in human T cells

    Nurmi, S. M., Autero, M., Raunio, A. K., Gahmberg, C. G. & Fagerholm, S. C. Jan 2007 In : Journal of Biological Chemistry. 282, 2, p. 968-975 8 p.

    Research output: Contribution to journalArticle

  118. Cysteine scanning mutagenesis and disulfide mapping studies of the TatA component of the bacterial twin arginine translocase

    Greene, N. P., Porcelli, I., Buchanan, G., Hicks, M. G., Schermann, S. M., Palmer, T. & Berks, B. C. 2007 In : Journal of Biological Chemistry. 282, 33, p. 23937-23945 9 p.

    Research output: Contribution to journalArticle

  119. Export pathway selectivity of Escherichia coli twin arginine translocation signal peptides

    Tullman-Ercek, D., DeLisa, M. P., Kawarasaki, Y., Iranpour, P., Ribnicky, B., Palmer, T. & Georgiou, G. 2007 In : Journal of Biological Chemistry. 282, 11, p. 8309-8316 8 p.

    Research output: Contribution to journalArticle

  120. Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase

    Goransson, O., McBride, A., Hawley, S. A., Ross, F. A., Shpiro, N., Foretz, M., Viollet, B., Hardie, D. G. & Sakamoto, K. 2007 In : Journal of Biological Chemistry. 282, 45, p. 32549-32560 12 p.

    Research output: Contribution to journalArticle

  121. Protein kinase CK2, cystic fibrosis transmembrane conductance regulator, and the deltaF508 mutation: F508 deletion disrupts a kinase-binding site

    Treharne, K. J., Crawford, R. M., Xu, Z., Chen, J-H., Best, O. G., Schulte, E. A., Gruenert, D. C., Wilson, S. M., Sheppard, D. N., Kunzelmann, K. & Mehta, A. 2007 In : Journal of Biological Chemistry. 282, 14, p. 10804-10813 10 p.

    Research output: Contribution to journalArticle

  122. The non-mevalonate pathway of isoprenoid precursor biosynthesis

    Hunter, W. N. 2007 In : Journal of Biological Chemistry. 282, 30, p. 21573-21577 5 p.

    Research output: Contribution to journalArticle

  123. The role of inositol acylation and inositol deacylation in the Toxoplasma gondii glycosylphosphatidylinositol biosynthetic pathway

    Smith, T. G. . T., Kimmel, J., Azzouz, N., Shams-Eldin, H. & Schwarz, R. T. 2007 In : Journal of Biological Chemistry. 282, 44, p. 32032-32042 11 p.

    Research output: Contribution to journalArticle

  124. The role of the fibronectin IGD motif in stimulating fibroblast migration

    Millard, C. J., Ellis, I. R., Pickford, A. R., Schor, A. M., Schor, S. L. & Campbell, I. D. 2007 In : Journal of Biological Chemistry. 282, 49, p. 35530-35535 6 p.

    Research output: Contribution to journalArticle

  125. Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-β pathways

    Sapkota, G., Knockaert, M., Alarcón, C., Montalvo, E., Brivanlou, A. H. & Massagué, J. 29 Dec 2006 In : Journal of Biological Chemistry. 281, 52, p. 40412-40419 8 p.

    Research output: Contribution to journalArticle

  126. Regulation of MAPK-activated protein kinase 5 activity and subcellular localization by the atypical MAPK ERK4/MAPK4

    Aberg, E., Perander, M., Johansen, B., Julien, C., Meloche, S., Keyse, S. M. & Seternes, O-M. 17 Nov 2006 In : Journal of Biological Chemistry. 281, 46, p. 35499-510 12 p.

    Research output: Contribution to journalArticle

  127. Siglec-7 undergoes a major conformational change when complexed with the α(2,8)-disialylganglioside GT1b

    Attrill, H., Imamura, A., Sharma, R. S., Kiso, M., Crocker, P. R. & Van Aalten, D. M. F. 27 Oct 2006 In : Journal of Biological Chemistry. 281, 43, p. 32774-32783 10 p.

    Research output: Contribution to journalArticle

  128. A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160

    Ramm, G., Larance, M., Guilhaus, M. & James, D. E. 29 Sep 2006 In : Journal of Biological Chemistry. 281, 39, p. 29174-29180 7 p.

    Research output: Contribution to journalArticle

  129. Screening-based discovery and structural dissection of a novel family 18 chitinase inhibitor

    Schüttelkopf, A. W., Andersen, O. A., Rao, F. V., Allwood, M., Lloyd, C., Eggleston, I. M. & van Aalten, D. M. F. 15 Sep 2006 In : Journal of Biological Chemistry. 281, 37, p. 27278-27285 8 p.

    Research output: Contribution to journalArticle

  130. Oxidant-induced activation of type I protein kinase A is mediated by RI subunit interprotein disulfide bond formation

    Brennan, J. P., Bardswell, S. C., Burgoyne, J. R., Fuller, W., Schroder, E., Wait, R., Begum, S., Kentish, J. C. & Eaton, P. 4 Aug 2006 In : Journal of Biological Chemistry. 281, 31, p. 21827-21836 10 p.

    Research output: Contribution to journalArticle

  131. An asymmetric contribution to gamma-aminobutyric type a receptor function of a conserved lysine within TM2-3 of alpha 1, beta 2, and gamma 2 subunits

    Hales, T. G., Deeb, T. Z., Tang, H., Bollan, K. A., King, D. P., Johnson, S. J. & Connolly, C. N. 23 Jun 2006 In : Journal of Biological Chemistry. 281, 25, p. 17034-17043 10 p.

    Research output: Contribution to journalArticle

  132. Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo

    Cole, A. R., Causeret, F., Yadirgi, G., Hastie, C. J., Mclauchlan, H., McManus, E. J., Hernandez, F., Eickholt, B. J., Nikolic, M., Sutherland, C. & Sutherland, C. 16 Jun 2006 In : Journal of Biological Chemistry. 281, 24, p. 16591-16598 8 p.

    Research output: Contribution to journalArticle

  133. Structural basis of reduction-dependent activation of human cystatin F

    Schüttelkopf, A. W., Hamilton, G., Watts, C. & van Aalten, D. M. F. 16 Jun 2006 In : Journal of Biological Chemistry. 281, 24, p. 16570-16575 6 p.

    Research output: Contribution to journalArticle

  134. Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and α4β2 nicotinic acetylcholine receptors

    Hales, T. G., Dunlop, J. I., Deeb, T. Z., Carland, J. E., Kelley, S. P., Lambert, J. J. & Peters, J. A. Mar 2006 In : Journal of Biological Chemistry. 281, 12, p. 8062-8071 10 p.

    Research output: Contribution to journalArticle

  135. Outer chain N-glycans are required for cell wall integrity and virulence of Candida albicans

    Bates, S., Hughes, H. B., Munro, C. A., Thomas, W. P. H., MacCallum, D. M., Bertram, G., Atrih, A., Ferguson, M. A. J., Brown, A. J. P., Odds, F. C. & Gow, N. A. R. 6 Jan 2006 In : Journal of Biological Chemistry. 281, 1, p. 90-98 9 p.

    Research output: Contribution to journalArticle

  136. An unusual twin: his arrangement in the pore of ammonia channels is essential for substrate conductance

    Javelle, A., Lupo, D., Zheng, L., Li, X-D., Winkler, F. K. & Merrick, M. 2006 In : Journal of Biological Chemistry. 281, 51, p. 39492-8 7 p.

    Research output: Contribution to journalArticle

  137. Analysis of nucleosome repositioning by yeast ISWI and Chd1 chromatin remodeling complexes

    Stockdale, C., Flaus, A., Ferreira, H. & Owen-Hughes, T. 2006 In : Journal of Biological Chemistry. 281, 24, p. 16279-88 10 p.

    Research output: Contribution to journalArticle

  138. Cysteine-scanning mutagenesis and disulfide mapping studies of the conserved domain of the twin-arginine translocase TatB component

    Lee, P. A., Orriss, G. L., Buchanan, G., Greene, N. P., Bond, P. J., Punginelli, C., Jack, R. L., Sansom, M. S. P., Berks, B. C. & Palmer, T. 2006 In : Journal of Biological Chemistry. 281, 45, p. 34072-34085 14 p.

    Research output: Contribution to journalArticle

  139. The substrate radical of Escherichia coli oxygen-independent coproporphyrinogen III oxidase HemN

    Layer, G., Pierik, A. J., Trost, M., Rigby, S. E., Leech, H. K., Grage, K., Breckau, D., Astner, I., Jänsch, L., Heathcote, P., Warren, M. J., Heinz, D. W. & Jahn, D. 2006 In : Journal of Biological Chemistry. 281, 23, p. 15727-15734 8 p.

    Research output: Contribution to journalArticle

  140. Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking

    Larance, M., Ramm, G., Stöckli, J., van Dam, E. M., Winata, S., Wasinger, V., Simpson, F., Graham, M., Junutula, J. R., Guilhaus, M. & James, D. E. 11 Nov 2005 In : Journal of Biological Chemistry. 280, 45, p. 37803-37813 11 p.

    Research output: Contribution to journalArticle

  141. Deletion of the glucosidase II gene in Trypanosoma brucei reveals novel N-glycosylation mechanisms in the biosynthesis of variant surface glycoprotein

    Jones, D. C., Mehlert, A., Guther, M. L. S. & Ferguson, M. A. J. 28 Oct 2005 In : Journal of Biological Chemistry. 280, 43, p. 35929-35942 14 p.

    Research output: Contribution to journalArticle

  142. The N-acetyl-d-glucosaminylphosphatidylinositol De-N-acetylase of glycosylphosphatidylinositol biosynthesis is a zinc metalloenzyme

    Urbaniak, M. D., Crossman, A., Chang, T., Smith, T. K., van Aalten, D. M. F. & Ferguson, M. A. J. 17 Jun 2005 In : Journal of Biological Chemistry. 280, 24, p. 22831-22838 8 p.

    Research output: Contribution to journalArticle

  143. Cell surface expression of 5-hydroxytryptamine type 3 receptors is promoted by RIC-3

    Cheng, A., McDonald, N. A. & Connolly, C. N. 10 Jun 2005 In : Journal of Biological Chemistry. 280, 23, p. 22502-22507 6 p.

    Research output: Contribution to journalArticle

  144. The suppression of galactose metabolism in procylic form Trypanosoma brucei causes cessation of cell growth and alters procyclin glycoprotein structure and copy number

    Roper, J. R., Guther, M. L. S., MacRae, J. I., Prescott, A. R., Hallyburton, I., Acosta-Serrano, A. & Ferguson, M. A. J. 20 May 2005 In : Journal of Biological Chemistry. 280, 20, p. 19728-19736 9 p.

    Research output: Contribution to journalArticle

  145. Role of T-loop phosphorylation in PDK1 activation, stability, and substrate binding

    Komander, D., Kular, G., Deak, M., Alessi, D. R. & van Aalten, D. M. F. 13 May 2005 In : Journal of Biological Chemistry. 280, 19, p. 18797-18802 6 p.

    Research output: Contribution to journalArticle

  146. Structural characterization of NETNES, a novel glycoconjugate in Trypanosoma cruzi epimastigotes

    MacRae, J. I., Acosta-Serrano, A., Morrice, N. A., Mehlert, A. & Ferguson, M. A. J. 1 Apr 2005 In : Journal of Biological Chemistry. 280, 13, p. 12201-12211 11 p.

    Research output: Contribution to journalArticle

  147. Crystal structure and binding properties of the Serratia marcescens chitin-binding protein CBP21

    Vaaje-Kolstad, G., Houston, D. R., Riemen, A. H. K., Eijsink, V. G. H. & van Aalten, D. M. F. 25 Mar 2005 In : Journal of Biological Chemistry. 280, 12, p. 11313-11319 7 p.

    Research output: Contribution to journalArticle

  148. Constitutive activation of GSK3 down-regulates glycogen synthase abundance and glycogen deposition in rat skeletal muscle cells

    MacAulay, K., Blair, A. S., Hajduch, E., Terashima, T., Baba, O., Sutherland, C. & Hundal, H. S. 11 Mar 2005 In : Journal of Biological Chemistry. 280, 10, p. 9509-9518 10 p.

    Research output: Contribution to journalArticle

  149. The murine Cyp1a1 gene is expressed in a restricted spatial and temporal pattern during embryonic development

    Campbell, S. J., Henderson, C. J., Anthony, D. C., Davidson, D., Clark, A. J. & Wolf, C. R. 18 Feb 2005 In : Journal of Biological Chemistry. 280, 7, p. 5828-5835 8 p.

    Research output: Contribution to journalArticle

  150. Trypanosoma brucei glycoproteins contain novel giant poly-N-acetyllactosamine carbohydrate chains

    Atrih, A., Richardson, J. M., Prescott, A. R. & Ferguson, M. A. J. 14 Jan 2005 In : Journal of Biological Chemistry. 280, 2, p. 865-871 7 p.

    Research output: Contribution to journalArticle

  151. AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line

    Rencurel, F., Stenhouse, A., Hawley, S. A., Friedberg, T., Hardie, D. G., Sutherland, C. & Wolf, C. R. 2005 In : Journal of Biological Chemistry. 280, 6, p. 4367-4373 7 p.

    Research output: Contribution to journalArticle

  152. Mnt1p and Mnt2p of Candida albicans are partially redundant alpha-1,2-mannosyltransferases that participate in O-linked mannosylation and are required for adhesion and virulence

    Munro, C. A., Bates, S., Buurman, E. T., Hughes, H. B., MacCallum, D. M., Bertram, G., Atrih, A., Ferguson, M. A. J., Bain, J. M., Brand, A., Hamilton, S., Westwater, C., Thomson, L. M., Brown, A. J. P., Odds, F. C. & Gow, N. A. R. 2005 In : Journal of Biological Chemistry. 280, 2, p. 1051-1060 10 p.

    Research output: Contribution to journalArticle

  153. Siglec-5 (CD170)can mediate inhibitory signaling in the absence of immunoreceptor tyrosine-based inhibitory motif phosphorylation

    Avril, T., Freeman, S. D., Attrill, H., Clarke, R. G. & Crocker, P. R. 2005 In : Journal of Biological Chemistry. 280, 20, p. 19843-19851 9 p.

    Research output: Contribution to journalArticle

  154. TBP-TAF complex SL1 directs RNA polymerase I pre-initiation complex formation and stabilizes upstream binding factor at the rDNA promoter

    Friedrich, J. K., Panov, K. I., Cabart, P., Russell, J. & Zomerdijk, J. C. B. M. 2005 In : Journal of Biological Chemistry. 280, 33, p. 29551-29558 8 p.

    Research output: Contribution to journalArticle

  155. GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons

    Cole, A. R., Knebel, A., Morrice, N. A., Robertson, L. A., Irving, A. J., Connolly, C. N. & Sutherland, C. 26 Nov 2004 In : Journal of Biological Chemistry. 279, 48, p. 50176-50180 5 p.

    Research output: Contribution to journalArticle

  156. Both nuclear-cytoplasmic shuttling of the dual specificity phosphatase MKP-3 and its ability to anchor MAP kinase in the cytoplasm are mediated by a conserved nuclear export signal

    Karlsson, M., Mathers, J., Dickinson, R. J., Mandl, M. & Keyse, S. M. 1 Oct 2004 In : Journal of Biological Chemistry. 279, 40, p. 41882-91 10 p.

    Research output: Contribution to journalArticle

  157. Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo

    Saville, M. K., Sparks, A., Xirodimas, D. P., Wardrop, J., Stevenson, L. F., Bourdon, J-C., Woods, Y. L. & Lane, D. P. 1 Oct 2004 In : Journal of Biological Chemistry. 279, 40, p. 42169-42181 13 p.

    Research output: Contribution to journalArticle

  158. A Kazal-like extracellular serine protease inhibitor from Phytophthora infestans targets the tomato pathogenesis-related protease P69B

    Tian, M., Huitema, E., da Cunha, L., Torto-Alalibo, T. & Kamoun, S. 18 Jun 2004 In : Journal of Biological Chemistry. 279, 25, p. 26370-26377 8 p.

    Research output: Contribution to journalArticle

  159. Ammonium sensing in Escherichia coli.: role of the ammonium transporter AmtB and AmtB-GlnK complex formation

    Javelle, A., Severi, E., Thornton, J. & Merrick, M. 2004 In : Journal of Biological Chemistry. 279, 10, p. 8530-8 9 p.

    Research output: Contribution to journalArticle

  160. Dual action of antimonial drugs on thiol redox metabolism in the human pathogen Leishmania donovani

    Wyllie, S., Cunningham, M. L. & Fairlamb, A. H. 2004 In : Journal of Biological Chemistry. 279, 38, p. 39925-39932 8 p.

    Research output: Contribution to journalArticle

  161. Human PTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation

    Jowsey, P. A., Doherty, A. J. & Rouse, J. 2004 In : Journal of Biological Chemistry. 279, 53, p. 55562-55569 8 p.

    Research output: Contribution to journalArticle

  162. Novel phenotypes of Escherichia coli tat mutants revealed by global gene expression and phenotypic analysis

    Ize, B., Porcelli, I., Lucchini, S., Hinton, J. C., Berks, B. C. & Palmer, T. 2004 In : Journal of Biological Chemistry. 279, 46, p. 47543-47554 12 p.

    Research output: Contribution to journalArticle

  163. p14 arf promotes small ubiquitin-like modifier conjugation of Werners helicase

    Woods, Y. L., Xirodimas, D. P., Prescott, A. R., Sparks, A., Lane, D. P. & Saville, M. K. 2004 In : Journal of Biological Chemistry. 279, 48, p. 50157-50166 10 p.

    Research output: Contribution to journalArticle

  164. Phosphorylation of a distinct structural form of phosphatidylinositol transfer protein alpha at Ser166 by protein kinase C disrupts receptor-mediated phospholipase C signaling by inhibiting delivery of phosphatidylinositol to membranes

    Morgan, C. P., Skippen, A., Segui, B., Ball, A., Allen-Baume, V., Larijani, B., Murray-Rust, J., McDonald, N., Sapkota, G., Morrice, N. & Cockcroft, S. 2004 In : Journal of Biological Chemistry. 279, 45, p. 47159-47171 13 p.

    Research output: Contribution to journalArticle

  165. Primary cultured neurons devoid of cellular prion display lower responsiveness to Staurosporine through the control of p53 at both transcriptional and post-transcriptional levels

    Paitel, E., Sunyach, C., da Costa, C. A., Bourdon, J-C., Vincent, B. & Checler, F. 2004 In : Journal of Biological Chemistry. 279, 1, p. 612-618 7 p.

    Research output: Contribution to journalArticle

  166. The surface coat of the mammal-dwelling infective trypomastigote stage of Trypanosoma cruzi is formed by highly diverse immunogenic mucins

    Buscaglia, C. A. ., Campo, V. A., Di Noia, J. M., Torrecilhas, A. C. T., De Marchi, C. R., Ferguson, M. A. J., Frasch, A. C. C. & Almeida, I. C. 2004 In : Journal of Biological Chemistry. 279, 16, p. 15860-15869 10 p.

    Research output: Contribution to journalArticle

  167. Characterization of a low molecular weight glycolipid antigen from Cryptosporidium parvum

    Priest, J. W., Mehlert, A., Arrowood, M. J., Riggs, M. W. & Ferguson, M. A. J. 26 Dec 2003 In : Journal of Biological Chemistry. 278, 52, p. 52212-52222 11 p.

    Research output: Contribution to journalArticle

  168. Ether phospholipids and glycosylinositolphospholipids are not required for amastigote virulence or for inhibition of macrophage activation by Leishmania major

    Zufferey, R., Allen, S., Barron, T., Sullivan, D. R., Denny, P. W., Almeida, I. C., Smith, D. F., Turco, S. J., Ferguson, M. A. J. & Beverley, S. M. 7 Nov 2003 In : Journal of Biological Chemistry. 278, 45, p. 44708-44718 11 p.

    Research output: Contribution to journalArticle

  169. The modifier subunit of drosophila glutamate-cysteine ligase regulates catalytic activity by covalent and noncovalent interactions and influences glutathione homeostasis in vivo*

    Fraser, J. A., Kansagra, P., Kotecki, C., Saunders, R. D. C. & McLellan, L. I. Nov 2003 In : Journal of Biological Chemistry. 278, 47, p. 46369-46377 9 p.

    Research output: Contribution to journalArticle

  170. Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells

    Morrow, V. A., Foufelle, F., Connell, J. M. C., Petrie, J., Gould, G. W. & Salt, I. P. Aug 2003 In : Journal of Biological Chemistry. 278, 34, p. 31629-31639 11 p.

    Research output: Contribution to journalArticle

  171. Cell surface expression of 5-hydroxytryptamine type 3 receptors is controlled by an endoplasmic reticulum retention signal

    Boyd, G. W., Doward, A. I., Kirkness, E. F., Millar, N. S. & Connolly, C. N. 25 Jul 2003 In : Journal of Biological Chemistry. 278, 30, p. 27681-27687 7 p.

    Research output: Contribution to journalArticle

  172. Biochemical and structural analysis of the molybdenum cofactor biosynthesis protein MobA

    Guse, A., Stevenson, C. E. M., Kuper, J., Buchanan, G., Schwarz, G., Giordano, G., Magalon, A., Mendel, R. R., Lawson, D. M. & Palmer, T. 11 Jul 2003 In : Journal of Biological Chemistry. 278, 28, p. 25302-25307 6 p.

    Research output: Contribution to journalArticle

  173. Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi

    Elsby, R., Kitteringham, N. R., Goldring, C. E., Lovatt, C. A., Chamberlain, M., Henderson, C. J., Wolf, C. R. & Park, B. K. 20 Jun 2003 In : Journal of Biological Chemistry. 278, 25, p. 22243-22249 7 p.

    Research output: Contribution to journalArticle

  174. High glucose inhibits insulin-stimulated nitric oxide production without reducing endothelial nitric-oxide synthase Ser¹¹⁷⁷ phosphorylation in human aortic endothelial cells

    Salt, I. P., Morrow, V. A., Brandie, F. M., Connell, J. M. C. & Petrie, J. May 2003 In : Journal of Biological Chemistry. 278, 21, p. 18791-18797 7 p.

    Research output: Contribution to journalArticle

  175. Oligomerization of the human ARF tumor suppressor and its response to oxidative stress

    Menendez, S., Khan, Z., Coomber, D., Lane, D., Higgins, M., Koufali, M. M. & Lain, S. May 2003 In : Journal of Biological Chemistry. 278, 21, p. 18720-18729 10 p.

    Research output: Contribution to journalArticle

  176. Regulation of protein kinase Cnu by the B-cell antigen receptor

    Matthews, S. A., Dayalu, R., Thompson, L. J. & Scharenberg, A. M. Mar 2003 In : Journal of Biological Chemistry. 278, 11, p. 9086-9091 6 p.

    Research output: Contribution to journalArticle

  177. Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi

    Martins, L. M., Turk, B. E., Cowling, V., Borg, A., Jarrell, E. T., Cantley, L. C. & Downward, J. 2003 In : Journal of Biological Chemistry. 278, 49, p. 49417-27 11 p.

    Research output: Contribution to journalArticle

  178. GABAA receptor composition is determined by distinct assembly signals within α and β subunits

    Bollan, K., King, D., Robertson, L. A., Brown, K., Taylor, P. M., Moss, S. J. & Connolly, C. N. 2003 In : Journal of Biological Chemistry. 278, 7, p. 4747-4755 9 p.

    Research output: Contribution to journalArticle

  179. Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase

    Henderson, C. J., Otto, D. M. E., Carrie, D., Magnuson, M. A., McLaren, A. W., Rosewell, I. & Wolf, C. R. 2003 In : Journal of Biological Chemistry. 278, 15, p. 13480-13486 7 p.

    Research output: Contribution to journalArticle

  180. Post-transcriptional control of human maxiK potassium channel activity and acute oxygen sensitivity by chronic hypoxia

    Hartness, M. E., Brazier, S. P., Peers, C., Bateson, A. N., Ashford, M. L. J. & Kemp, P. J. 2003 In : Journal of Biological Chemistry. 278, 51, p. 51422-51432 11 p.

    Research output: Contribution to journalArticle

  181. Stoichiometry of active smad-transcription factor complexes on DNA

    Inman, G. J. & Hill, C. S. 27 Dec 2002 In : Journal of Biological Chemistry. 277, 52, p. 51008-16 9 p.

    Research output: Contribution to journalArticle

  182. Cloning of Trypanosoma brucei and Leishmania major genes encoding the GlcNAc-phosphatidylinositol De-N-acetylase of glycosylphosphatidylinositol biosynthesis that is essential to the African Sleeping sickness parasite

    Chang, T., Milne, K. G., Guther, M. L. S., Smith, T. K. & Ferguson, M. A. J. 20 Dec 2002 In : Journal of Biological Chemistry. 277, 51, p. 50176-50182 7 p.

    Research output: Contribution to journalArticle

  183. Partial structure of glutamic acid and alanine-rich protein, a major surface glycoprotein of the insect stages of Trypanosoma congolense

    Thomson, L. M., Lamont, D. J., Mehlert, A., Barry, J. D. & Ferguson, M. A. J. 13 Dec 2002 In : Journal of Biological Chemistry. 277, 50, p. 48899-48904 6 p.

    Research output: Contribution to journalArticle

  184. Specificities of enzymes of glycosylphosphatidylinositol biosynthesis in trypanosoma brucei and HeLa cells

    Smith, T. K., Crossman, A., Paterson, M. J., Borissow, C. N., Brimacombe, J. S. & Ferguson, M. A. J. 4 Oct 2002 In : Journal of Biological Chemistry. 277, 40, p. 37147-37153 7 p.

    Research output: Contribution to journalArticle

  185. Genetic analysis of the twin arginine translocator secretion pathway in bacteria

    DeLisa, M. P., Samuelson, P., Palmer, T. & Georgiou, G. 16 Aug 2002 In : Journal of Biological Chemistry. 277, 33, p. 29825-29831 7 p.

    Research output: Contribution to journalArticle

  186. A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane

    Cragg, R. A., Christie, G. R., Phillips, S. R., Russi, R. M., Kury, S., Mathers, J. C., Taylor, P. M. & Ford, D. 21 Jun 2002 In : Journal of Biological Chemistry. 277, 25, p. 22789-22797 9 p.

    Research output: Contribution to journalArticle

  187. S-thiolation of HSP27 regulates its multimeric aggregate size independently of phosphorylation

    Eaton, P., Fuller, W. & Shattock, M. J. 14 Jun 2002 In : Journal of Biological Chemistry. 277, 24, p. 21189-21196 8 p.

    Research output: Contribution to journalArticle

  188. Insulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activity

    Patel, S., Lochhead, P. A., Rena, G., Fumagalli, S., Pende, M., Kozma, S. C., Thomas, G. & Sutherland, C. 22 Mar 2002 In : Journal of Biological Chemistry. 277, 12, p. 9889-9895 7 p.

    Research output: Contribution to journalArticle

  189. Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner

    Christie, G. R., Hajduch, E., Hundal, H. S., Proud, C. G. & Taylor, P. M. 22 Mar 2002 In : Journal of Biological Chemistry. 277, 12, p. 9952-9957 6 p.

    Research output: Contribution to journalArticle

  190. The globular domain of the proα1(I) N-propeptide is not required for secretion, processing by procollagen N-proteinase, or fibrillogenesis of type I collagen in mice

    Bornstein, P., Walsh, V., Tullis, J., Stainbrook, E., Bateman, J. F. & Hormuzdi, S. G. 25 Jan 2002 In : Journal of Biological Chemistry. 277, 4, p. 2605-2613 9 p.

    Research output: Contribution to journalArticle

  191. Phosphorylation of the cytoplasmic domain of the integrin CD18 chain by protein kinase C isoforms in leukocytes

    Fagerholm, S., Morrice, N., Gahmberg, C. G. & Cohen, P. 18 Jan 2002 In : Journal of Biological Chemistry. 277, 3, p. 1728-1738 11 p.

    Research output: Contribution to journalArticle

  192. Drosophila melanogaster glutamate-cysteine ligase activity is regulated by a modifier subunit with a mechanism of action similar to that of the mammalian form

    Fraser, J. A., Saunders, R. D. C. & McLellan, L. I. Jan 2002 In : Journal of Biological Chemistry. 277, 2, p. 1158-1165 8 p.

    Research output: Contribution to journalArticle

  193. Muscarinic receptors mediate phospholipase C-dependent activation of protein kinase B via Ca2+, ErbB3, and phosphoinositide 3-Kinase in 1321N1 astrocytoma cells

    Tang, X., Batty, I. H. & Downes, C. P. Jan 2002 In : Journal of Biological Chemistry. 277, 1, p. 338-344 7 p.

    Research output: Contribution to journalArticle

  194. A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi

    Oza, S. L., Tetaud, E., Ariyanayagam, M. R., Warnon, S. S. & Fairlamb, A. H. 2002 In : Journal of Biological Chemistry. 277, 39, p. 35853-35861 9 p.

    Research output: Contribution to journalArticle

  195. Passive acquisition of ligand by the MopII molbindin from Clostridium pasteurianum: structures of apo and oxyanion-bound forms

    Schuttelkopf, A. W., Harrison, J. A., Boxer, D. H. & Hunter, W. N. 2002 In : Journal of Biological Chemistry. 277, 17, p. 15013-15020 8 p.

    Research output: Contribution to journalArticle

  196. The donor substrate specificity beta 1,3-glucuronosyltransferase I toward UDP-glucoronic acid is determined by two crucial histidine and arginine residues

    Ouzzine, M., Gulberti, S., Levoin, N., Netter, P., Magdalou, J. & Fournel-Gigleux, S. 2002 In : Journal of Biological Chemistry. 277, 28, p. 25439-25445 7 p.

    Research output: Contribution to journalArticle

  197. Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts

    Dourdin, N., Bhatt, A. K., Dutt, P., Greer, P. A., Arthur, J. S. C., Elce, J. S. & Huttenlocher, A. 21 Dec 2001 In : Journal of Biological Chemistry. 276, 51, p. 48382-48388 7 p.

    Research output: Contribution to journalArticle

  198. The peroxisome proliferator-activated receptor delta promotes lipid accumulation in human macrophages

    Vosper, H., Patel, L., Graham, T. L., Khoudoli, G. A., Hill, A., Macphee, C. H., Pinto, I., Smith, S. A., Suckling, K. E., Wolf, C. R. & Palmer, C. N. A. Nov 2001 In : Journal of Biological Chemistry. 276, 47, p. 44258-44265 8 p.

    Research output: Contribution to journalArticle

  199. Chromatin-associated Protein Phosphatase I Regulates Aurora-B and Histone H3 Phosphorylation

    Murnion, M. E., Adams, R. R., Callister, D. M., Allis, C. D., Earnshaw, W. C. & Swedlow, J. R. 13 Jul 2001 In : Journal of Biological Chemistry. 276, 28, p. 26656-26665 10 p.

    Research output: Contribution to journalArticle

  200. Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling

    Glading, A., Uberall, F., Keyse, S. M., Lauffenburger, D. A. & Wells, A. 29 Jun 2001 In : Journal of Biological Chemistry. 276, 26, p. 23341-8 8 p.

    Research output: Contribution to journalArticle

  201. Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90RSK and cAMP-dependent protein kinase, but not its farnesylation at Cys433, is essential for LKB1 to suppress cell growth

    Sapkota, G. P., Kieloch, A., Lizcano, J. M., Lain, S., Arthur, J. . S. C., Williams, M. R., Morrice, N., Deak, M. & Alessi, D. R. 1 Jun 2001 In : Journal of Biological Chemistry. 276, 22, p. 19469-19482 14 p.

    Research output: Contribution to journalArticle

  202. Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1

    Slack, D. N., Seternes, O-M., Gabrielsen, M. & Keyse, S. M. 30 Jan 2001 In : Journal of Biological Chemistry. 276, 19, p. 16491-500 10 p.

    Research output: Contribution to journalArticle

  203. A direct interaction between the carboxyl-terminal region of CDC5L and the WD40 domain of PLRG1 is essential for pre-mRNA splicing

    Ajuh, P., Sleeman, J., Chusainow, J. & Lamond, A. I. 2001 In : Journal of Biological Chemistry. 276, 45, p. 42370-42381 12 p.

    Research output: Contribution to journalArticle

  204. Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease

    Kantachuvesiri, S., Fleming, S., Peters, J., Peters, B., Brooker, G., Lammie, A. G., McGrath, I., Kotelevtsev, Y. & Mullins, J. J. 2001 In : Journal of Biological Chemistry. 276, 39, p. 36727-33 7 p.

    Research output: Contribution to journalArticle

  205. Cloning, expression, and characterization of the acyl-CoA-binding protein in African trypanosomes

    Milne, K. G. & Ferguson, M. A. J. 28 Apr 2000 In : Journal of Biological Chemistry. 275, 17, p. 12503-12508 6 p.

    Research output: Contribution to journalArticle

  206. Reduction of nitrite to nitric oxide catalyzed by xanthine oxidoreductase

    Godber, B. L., Doel, J. J., Sapkota, G. P., Blake, D. R., Stevens, C. R., Eisenthal, R. & Harrison, R. 17 Mar 2000 In : Journal of Biological Chemistry. 275, 11, p. 7757-7763 7 p.

    Research output: Contribution to journalArticle

  207. Essential role of phosphoinositide 3-kinase in leptin-induced KATP channel activation in the rat CRI-G1 insulinoma cell line

    Harvey, J., McKay, N. G., Walker, K. S., Van der Kaay, J., Downes, C. P. & Ashford, M. L. J. 18 Feb 2000 In : Journal of Biological Chemistry. 275, 7, p. 4660-4669 10 p.

    Research output: Contribution to journalArticle

  208. Granulation rescue and developmental marking of juxtaglomerular cells using "piggy-BAC" recombination of the mouse ren locus

    Mullins, L. J., Payne, C. M., Kotelevtseva, N., Brooker, G., Fleming, S., Harris, S. & Mullins, J. J. 2000 In : Journal of Biological Chemistry. 275, 51, p. 40378-84 7 p.

    Research output: Contribution to journalArticle

  209. Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis

    Munsch, D., Watanabe-Fukunaga, R., Bourdon, J-C., Nagata, S., May, E., Yonish-Rouach, E. & Reisdorf, P. 2000 In : Journal of Biological Chemistry. 275, 6, p. 3867-3872 6 p.

    Research output: Contribution to journalArticle

  210. Interaction of Xenopus Cdc2 x cyclin A1 with the origin recognition complex

    Romanowski, P., Marr, J., Madine, M. A., Rowles, A., Blow, J. J., Gautier, J. & Laskey, R. A. 2000 In : Journal of Biological Chemistry. 275, 6, p. 4239-4243 5 p.

    Research output: Contribution to journalArticle

  211. Membrane localization of cyclic nucleotide phosphodiesterase 3 (PDES): two N-terminal, domains are required for the efficient targeting to, and association of, PDE3 with endoplasmic reticulum

    Shakur, Y., Takeda, K., Kenan, Y., Yu, Z-X., Rena, G., Brandt, D., Houslay, M. D., Degerman, E., Ferrans, V. J. & Manganiello, V. C. 2000 In : Journal of Biological Chemistry. 275, 49, p. 38749-38761 13 p.

    Research output: Contribution to journalArticle

  212. NF-kappa B inhibits glucocorticoid and cAMP-mediated expression of the phosphoenolpyruvate carboxykinase gene

    Waltner-Law, M., Daniels, M. C., Sutherland, C. & Granner, D. K. 2000 In : Journal of Biological Chemistry. 275, 41, p. 31847-31856 10 p.

    Research output: Contribution to journalArticle

  213. Sequential MCM/P1 subcomplex assembly is required to form a heterohexamer with replication licensing activity

    Prokhorova, T. A. & Blow, J. J. 2000 In : Journal of Biological Chemistry. 275, 4, p. 2491-2498 8 p.

    Research output: Contribution to journalArticle

  214. TatD is a cytoplasmic protein with DNase activity. No requirement for TatD family proteins in sec-independent protein export

    Wexler, M., Sargent, F., Jack, R. L., Stanley, N. R., Bogsch, E. G., Robinson, C., Berks, B. C. & Palmer, T. 2000 In : Journal of Biological Chemistry. 275, 22, p. 16717-16722 6 p.

    Research output: Contribution to journalArticle

  215. The molecular physiology of hepatic nuclear factor 3 in the regulation of gluconeogenesis

    Wang, J-C., Stafford, J. M., Scott, D. K., Sutherland, C. & Granner, D. K. 2000 In : Journal of Biological Chemistry. 275, 19, p. 14717-14721 5 p.

    Research output: Contribution to journalArticle

  216. Cell surface stability of gamma-aminobutyric acid type A receptors: dependence on protein kinase C activity and subunit composition

    Connolly, C. N., Kittler, J. T., Thomas, P., Uren, J. M., Brandon, N. J., Smart, T. G. & Moss, S. J. 17 Dec 1999 In : Journal of Biological Chemistry. 274, 51, p. 36565-36572 8 p.

    Research output: Contribution to journalArticle

  217. The procyclin repertoire of Trypanosoma brucei: identification and structural characterization of the Glu-Pro-rich polypeptides

    Acosta-Serrano, A., Cole, R. N., Mehlert, A., Lee, M. G-S., Ferguson, M. A. J. & Englund, P. T. 15 Oct 1999 In : Journal of Biological Chemistry. 274, 42, p. 29763-29771 9 p.

    Research output: Contribution to journalArticle

  218. A novel glycosylphosphatidylinositol in African trypanosomes: a possible catabolic intermediate

    Milne, K. G., Ferguson, M. A. J. & Englund, P. T. 15 Jan 1999 In : Journal of Biological Chemistry. 274, 3, p. 1465-1471 7 p.

    Research output: Contribution to journalArticle

  219. Hydrogen peroxide induces intracellular calcium overload by activation of a non-selective cation channel in an insulin-secreting cell line

    Herson, P. S., Lee, K., Pinnock, R. D., Hughes, J. & Ashford, M. L. J. 8 Jan 1999 In : Journal of Biological Chemistry. 274, 2, p. 833-841 9 p.

    Research output: Contribution to journalArticle

  220. Characterization of serine 916 as an in vivo autophosphorylation site for protein kinase D/Protein kinase Cmu

    Matthews, S. A., Rozengurt, E. & Cantrell, D. 1999 In : Journal of Biological Chemistry. 274, 37, p. 26543-9 7 p.

    Research output: Contribution to journalArticle

  221. Dominant negative forms of Akt (protein kinase B) and atypical protein kinase Cλ do not prevent insulin inhibition of phosphoenolpyruvate carboxykinase gene transcription

    Kotani, K., Ogawa, W., Hino, Y., Kitamura, T., Ueno, H., Sano, W., Sutherland, C., Granner, D. K. & Kasuga, M. 1999 In : Journal of Biological Chemistry. 274, 30, p. 21305-21312 8 p.

    Research output: Contribution to journalArticle

  222. Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

    Rena, G., Guo, S., Cichy, S. C., Unterman, T. G. & Cohen, P. 1999 In : Journal of Biological Chemistry. 274, 24, p. 17179-17183 5 p.

    Research output: Contribution to journalArticle

  223. Activation of the Ras mitogen-activated protein kinase ribosomal protein kinase pathway is not required for the repression of phosphoenolpyruvate carboxykinase gene transcription by insulin

    Sutherland, C., Waltner-Law, M., Gnudi, L., Kahn, B. B. & Granner, D. K. 1998 In : Journal of Biological Chemistry. 273, 6, p. 3198-3204 7 p.

    Research output: Contribution to journalArticle

  224. An essential component of a novel bacterial protein export system with homologues in plastids and mitochondria

    Bogsch, E. G., Sargent, F., Stanley, N. R., Berks, B. C., Robinson, C. & Palmer, T. 1998 In : Journal of Biological Chemistry. 273, 29, p. 18003-18006 4 p.

    Research output: Contribution to journalArticle

  225. Renin-1 is essential for normal renal juxtaglomerular cell granulation and macula densa morphology

    Clark, A. F., Sharp, M. G. F., Morley, S. D., Fleming, S., Peters, J. & Mullins, J. J. 18 Jul 1997 In : Journal of Biological Chemistry. 272, 29, p. 18185-18190 6 p.

    Research output: Contribution to journalArticle

  226. Autolysis, Ca2+ requirement, and heterodimer stability in m-calpain

    Elce, J. S., Hegadorn, C. & Arthur, J. S. C. 25 Apr 1997 In : Journal of Biological Chemistry. 272, 17, p. 11268-11275 8 p.

    Research output: Contribution to journalArticle

  227. Bryostatin 1 induces biphasic activation of protein kinase D in intact cells

    Matthews, S. A., Pettit, G. R. & Rozengurt, E. 1997 In : Journal of Biological Chemistry. 272, 32, p. 20245-50 6 p.

    Research output: Contribution to journalArticle

  228. Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase

    Hawley, S. A., Davison, M., Woods, A., Davies, S. P., Beri, R. K., Carling, D. & Hardie, D. G. 1 Nov 1996 In : Journal of Biological Chemistry. 271, 44, p. 27879-27887 9 p.

    Research output: Contribution to journalArticle

  229. Substrate specificity of the dolichol phosphate mannose: Glucosaminyl phosphatidylinositol α1-4-mannosyltransferase of the glycosylphosphatidylinositol biosynthetic pathway of African trypanosomes

    Smith, T. K., Cottaz, S., Brimacombe, J. S. & Ferguson, M. A. J. 15 Mar 1996 In : Journal of Biological Chemistry. 271, 11, p. 6476-6482 7 p.

    Research output: Contribution to journalArticle

  230. Insulin regulation of phosphoenolpyruvate carboxykinase gene expression does not require activation of the Ras mitogen-activated protein kinase signaling pathway

    Gabbay, R. A., Sutherland, C., Gnudi, L., Kahn, B. B., O'Brien, R. M., Granner, D. K. & Flier, J. S. 26 Jan 1996 In : Journal of Biological Chemistry. 271, 4, p. 1890-1897 8 p.

    Research output: Contribution to journalArticle

  231. Assembly and cell surface expression of heteromeric and homomeric gamma-aminobutyric acid type A receptors

    Connolly, C. N., Krishek, B. J., McDonald, B. J., Smart, T. G. & Moss, S. J. 5 Jan 1996 In : Journal of Biological Chemistry. 271, 1, p. 89-96 8 p.

    Research output: Contribution to journalArticle

  232. Analysis of the signaling pathway involved in the regulation of hexokinase II gene transcription by insulin

    Osawa, H., Sutherland, C., Robey, R. B., Printz, R. L. & Granner, D. K. 1996 In : Journal of Biological Chemistry. 271, 28, p. 16690-16694 5 p.

    Research output: Contribution to journalArticle

  233. PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

    Alessi, D. R., Cuenda, A., Cohen, P., Dudley, D. T. & Saltiel, A. R. 17 Nov 1995 In : Journal of Biological Chemistry. 270, 46, p. 27489-27494 6 p.

    Research output: Contribution to journalArticle

  234. The lipid structure of the glycosylphosphatidylinositol-anchored mucin-like sialic acid acceptors of Trypanosoma cruzi changes during parasite differentiation from epimastigotes to infective metacyclic trypomastigote forms.

    Serrano, A. A., Schenkman, S., Yoshida, N., Mehlert, A., Richardson, J. M. & Ferguson, M. A. J. 10 Nov 1995 In : Journal of Biological Chemistry. 270, 45, p. 27244-27253 10 p.

    Research output: Contribution to journalArticle

  235. Structures of the glycosyl-phosphatidylinositol anchors of porcine and human renal membrane dipeptidase.: Comprehensive structural studies on the porcine anchor and interspecies comparison of the glycan core structures.

    Brewis, I. A., Ferguson, M. A. J., Mehlert, A., Turner, A. J. & Hooper, N. M. 29 Sep 1995 In : Journal of Biological Chemistry. 270, 39, p. 22946-22956 11 p.

    Research output: Contribution to journalArticle

  236. Newly synthesized transferrin receptors can be detected in the endosome before they appear on the cell surface

    Futter, C. E., Connolly, C. N., Cutler, D. F. & Hopkins, C. R. 5 May 1995 In : Journal of Biological Chemistry. 270, 18, p. 10999-11003 5 p.

    Research output: Contribution to journalArticle

  237. p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1

    Milne, D. M., Campbell, L. E., Campbell, D. G. & Meek, D. W. 10 Mar 1995 In : Journal of Biological Chemistry. 270, 10, p. 5511-5518 8 p.

    Research output: Contribution to journalArticle

  238. Primary structure of CD52

    Treumann, A., Lifely, M. R., Schneider, P. & Ferguson, M. A. J. 1 Jan 1995 In : Journal of Biological Chemistry. 270, 11, p. 6088-6099 12 p.

    Research output: Contribution to journalArticle

  239. Evidence that aspartic acid 301 is a critical substrate-contact residue in the active site of cytochrome P450 2D6

    Ellis, S. W., Hayhurst, G. P., Smith, G., Lightfoot, T., Wong, M. M. S., Simula, A. P., Ackland, M. J., Sternberg, M. J. E., Lennard, M. S., Tucker, G. T. & Wolf, C. R. 1995 In : Journal of Biological Chemistry. 270, 49, p. 29055-29058 4 p.

    Research output: Contribution to journalComment/debate

  240. The effects of phenylmethylsulfonyl fluoride on inositol-acylation and fatty acid remodeling in African trypanosomes

    Güther, M. L. S., Masterson, W. J. & Ferguson, M. A. J. 15 Jul 1994 In : Journal of Biological Chemistry. 269, 28, p. 18694-18701 8 p.

    Research output: Contribution to journalArticle

  241. Phosphorylation of the tumor suppressor protein p53 by mitogen-activated protein kinases

    Milne, D. M., Campbell, D. G., Caudwell, F. B. & Meek, D. W. 25 Mar 1994 In : Journal of Biological Chemistry. 269, 12, p. 9253-9260 8 p.

    Research output: Contribution to journalArticle

  242. O- and N-Glycosylation of the Leishmania mexicana-secreted acid phosphatase: characterization of a new class of phosphoserine-linked glycans

    Ilg, T., Overath, P., Ferguson, M. A. J., Rutherford, T., Campbell, D. G. & McConville, M. J. 1 Jan 1994 In : Journal of Biological Chemistry. 269, 39, p. 24073-24081 9 p.

    Research output: Contribution to journalArticle

  243. Characterization of GDP-α-D-arabinopyranose, the precursor of D-Ara(p) in Leishmania major lipophosphoglycan

    Schneider, P., McConville, M. J. & Ferguson, M. A. J. 1 Jan 1994 In : Journal of Biological Chemistry. 269, 28, p. 18332-18337 6 p.

    Research output: Contribution to journalArticle

  244. Partial purification and characterization of the N-acetylglucosaminyl- phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol anchor biosynthesis in African trypanosomes

    Milne, K. G., Field, R. A., Masterson, W. J., Cottaz, S., Brimacombe, J. S. & Ferguson, M. A. J. 1 Jan 1994 In : Journal of Biological Chemistry. 269, 23, p. 16403-16408 6 p.

    Research output: Contribution to journalArticle

  245. Structures of glycosylphosphatidylinositol membrane anchors from Saccharomyces cerevisiae*

    Fankhauser, C., Homans, S. W., Thomas-Oates, J. E., McConville, M. J., Desponds, C., Conzelmann, A. & Ferguson, M. A. J. 1993 In : Journal of Biological Chemistry. 268, 35, p. 26365-26374 10 p.

    Research output: Contribution to journalArticle

  246. The glycoinositol phospholipids of Leishmania mexicana promastigotes: evidence for the presence of three distinct pathways of glycolipid biosynthesis

    McConville, M. J., Collidge, T. A. C., Ferguson, M. A. J. & Schneider, P. 1993 In : Journal of Biological Chemistry. 268, 21, p. 15595-604 10 p.

    Research output: Contribution to journalArticle

  247. The mechanism of inhibition of glycosylphosphatidylinositol anchor biosynthesis in Trypanosoma brucei by mannosamine

    Ralton, J. E., Milne, K., Güther, M. L. S., Field, R. A. & Ferguson, M. A. J. 1993 In : Journal of Biological Chemistry. 268, 32, p. 24183-24189 7 p.

    Research output: Contribution to journalArticle

  248. A murein hydrolase is the specific target of bulgecin in Escherichia coli

    Templin, M. F., Edwards, D. H. & Holtje, J-V. 5 Oct 1992 In : Journal of Biological Chemistry. 267, 28, p. 20039-20043 5 p.

    Research output: Contribution to journalArticle

  249. Refined structure of the lipophosphoglycan of Leishmania-donovani

    Thomas, J. R., McConville, M. J., Thomas-Oates, J. E., Homans, S. W., Ferguson, M. A. J., Gorin, P. A. J., Greis, K. D. & Turco, S. J. 5 Apr 1992 In : Journal of Biological Chemistry. 267, 10, p. 6829-6833 5 p.

    Research output: Contribution to journalArticle

  250. Structural studies on the glycosylphosphatidylinositol membrane anchor of Trypanosoma cruzi 1G7-antigen: The structure of the glycan core

    Guther, M. L. S., de Almeida, M. L. C., Yoshida, N. & Ferguson, M. A. J. 5 Apr 1992 In : Journal of Biological Chemistry. 267, 10, p. 6820-6828 9 p.

    Research output: Contribution to journalArticle

  251. Structure of Leishmania mexicana lipophosphoglycan

    Ilg, T., Etges, R., Overath, P., McConville, M. J., Thomas-Oates, J., Thomas, J., Homans, S. W. & Ferguson, M. A. 5 Apr 1992 In : Journal of Biological Chemistry. 267, 10, p. 6834-40 7 p.

    Research output: Contribution to journalArticle

  252. Purification and characterization of an extracellular phosphoglycan from Leishmania donovani

    Greis, K. D., Turco, S. J., Thomas, J. R., McConville, M. J., Homans, S. W. & Ferguson, M. A. J. 25 Mar 1992 In : Journal of Biological Chemistry. 267, 9, p. 5876-5881 6 p.

    Research output: Contribution to journalArticle

  253. Complete structure of the glycan of lipopeptidophosphoglycan from Trypanosoma cruzi epimastigotes

    de Lederkremer, R. M., Lima, C., Ramirez, M. I., Ferguson, M. A. J., Homans, S. W. & Thomas-Oates, J. 15 Dec 1991 In : Journal of Biological Chemistry. 266, 35, p. 23670-23675 6 p.

    Research output: Contribution to journalArticle

  254. A cDNA encoding rabbit muscle protein phosphatase 1 alpha complements the Aspergillus cell cycle mutation, bimG11

    Doonan, J. H., MacKintosh, C., Osmani, S., Cohen, P., Bai, G., Lee, E. Y. & Morris, N. R. 1991 In : Journal of Biological Chemistry. 266, 28, p. 18889-18894 6 p.

    Research output: Contribution to journalArticle

  255. Structure of the lipophosphoglycan from Leishmania major

    McConville, M. J., Thomas-Oates, J. E., Ferguson, M. A. J. & Homans, S. W. 15 Nov 1990 In : Journal of Biological Chemistry. 265, 32, p. 19611-19623 13 p.

    Research output: Contribution to journalArticle

  256. Structure of the glycosyl-phosphatidylinositol membrane anchor of the Leishmania major promastigote surface protease.

    Schneider, P., Ferguson, M., McConville, M. J., Mehlert, A., Homans, S. W. & Bordier, C. 5 Oct 1990 In : Journal of Biological Chemistry. 265, 28, p. 16955-16964 10 p.

    Research output: Contribution to journalArticle

  257. Structures of the N-linked oligosaccharides of gp63, the major surface glycoprotein, from Leishmania mexicana amazonensis

    Olafson, R. W., Thomas, J. R., Ferguson, M. A. J., Dwek, R. A., Chaudhuri, M., Chang, K-P. & Rademacher, T. W. 25 Jul 1990 In : Journal of Biological Chemistry. 265, 21, p. 12240-12247 8 p.

    Research output: Contribution to journalArticle

  258. Glycolipid precursors for the membrane anchor of Trypanosoma brucei variant surface glycoproteins.: I. Can structure of the phosphatidylinositol-specific phospholipase C sensitive and resistant glycolipids

    Mayor, S., Menon, A. K., Cross, G. A. M., Ferguson, M. A. J., Dwek, R. A. & Rademacher, T. W. 15 Apr 1990 In : Journal of Biological Chemistry. 265, 11, p. 6164-6173 10 p.

    Research output: Contribution to journalArticle

  259. The calcium-binding site of clathrin light chains

    Näthke, I., Hill, B. L., Parham, P. & Brodsky, F. M. 1990 In : Journal of Biological Chemistry. 265, 30, p. 18621-18627 7 p.

    Research output: Contribution to journalArticle

  260. Structure of the phosphosaccharide-inositol core of the Leishmania donovani lipophosphoglycan

    Turco, S. J., Orlandi Jr., P. A., Homans, S. W., Ferguson, M. A. J., Dwek, R. A. & Rademacher, T. W. 25 Apr 1989 In : Journal of Biological Chemistry. 264, 12, p. 6711-6715 5 p.

    Research output: Contribution to journalArticle

  261. Candidate glycophospholipid precursor for the glycosylphosphatidylinositol membrane anchor of Trypanosoma brucei variant surface glycoproteins

    Menon, A. K., Mayor, S., Ferguson, M. A. J., Duszenko, M. & Cross, G. A. M. 5 Feb 1988 In : Journal of Biological Chemistry. 263, 4, p. 1970-1977 8 p.

    Research output: Contribution to journalArticle

  262. Both near ultraviolet radiation and the oxidizing agent hydrogen peroxide induce a 32-kDa stress protein in normal human skin fibroblasts

    Keyse, S. M. & Tyrrell, R. M. 25 Oct 1987 In : Journal of Biological Chemistry. 262, 30, p. 14821-5 5 p.

    Research output: Contribution to journalArticle

  263. Purification and characterization of a novel glycan-phosphatidylinositol-specific phospholipase C from Trypanosoma brucei

    Fox, J. A., Duszenko, M., Ferguson, M. A. J., Low, M. G. & Cross, G. A. M. 25 Nov 1986 In : Journal of Biological Chemistry. 261, 33, p. 15767-15771 5 p.

    Research output: Contribution to journalArticle

  264. Biosynthesis of Trypanosoma brucei variant surface glycoproteins.: N-Glycosylation and addition of a phosphatidylinositol membrane anchor

    Ferguson, M. A. J., Duszenko, M., Lamont, G. S., Overath, P. & Cross, G. A. M. 5 Jan 1986 In : Journal of Biological Chemistry. 261, 1, p. 356-362 7 p.

    Research output: Contribution to journalArticle

  265. Glycosyl-sn-1,2-dimyristylphosphatidylinositol is covalently linked to Trypanosoma brucei variant surface glycoprotein

    Ferguson, M. A. J., Low, M. G. & Cross, G. A. M. 25 Nov 1985 In : Journal of Biological Chemistry. 260, 27, p. 14547-14555 9 p.

    Research output: Contribution to journalArticle

  266. Trypanosoma brucei variant surface glycoprotein has a sn-1,2-dimyristyl glycerol membrane anchor at its COOH terminus

    Ferguson, M. A. J., Haldar, K. & Cross, G. A. M. 25 Apr 1985 In : Journal of Biological Chemistry. 260, 8, p. 4963-4968 6 p.

    Research output: Contribution to journalArticle

  267. Acylation of a Plasmodium falciparum merozoite surface antigen via sn-1,2-diacyl glycerol

    Haldar, K., Ferguson, M. A. J. & Cross, G. A. M. 25 Apr 1985 In : Journal of Biological Chemistry. 260, 8, p. 4969-4974 6 p.

    Research output: Contribution to journalArticle

  268. Myristylation of the membrane form of a Trypanosoma-brucei variant surface glycoprotein

    Ferguson, M. A. . J. & Cross, G. A. M. 10 Mar 1984 In : Journal of Biological Chemistry. 259, 5, p. 3011-3015 5 p.

    Research output: Contribution to journalArticle

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