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  1. MSK1 and 2 inhibit LPS induced prostaglandin production via an IL-10 feedback loop

    Mackenzie, K. F., Van Den Bosch, M. W. M., Naqvi, S., Elcombe, S. E., McGuire, V. A., Reith, A. D., Blackshear, P. J., Dean, J. L. & Arthur, J. S. C. 2013 In : Molecular and Cellular Biology.

    Research output: Contribution to journal › Article

  2. Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP Axis

    Rada, P., Rojo, A. I., Evrard-Todeschi, N., Innamorato, N. G., Cotte, A., Jaworski, T., Tobón-Velasco, J. C., Devijver, H., García-Mayoral, M. F., Van Leuven, F., Hayes, J. D., Bertho, G. & Cuadrado, A. 2012 In : Molecular and Cellular Biology. 32, 17, p. 3486-99, 14 p.

    Research output: Contribution to journal › Article

  3. Contribution of Casein Kinase 2 and Spleen Tyrosine Kinase to CFTR Trafficking and Protein Kinase A-Induced Activity

    Luz, S., Kongsuphol, P., Mendes, A. I., Romeiras, F., Sousa, M., Schreiber, R., Matos, P., Jordan, P., Mehta, A., Amaral, M. D., Kunzelmann, K. & Farinha, C. M. Nov-2011 In : Molecular and Cellular Biology. 31, 22, p. 4392-4404, 13 p.

    Research output: Contribution to journal › Article

  4. SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner

    Rada, P., Rojo, A. I., Chowdhry, S., McMahon, M., Hayes, J. D. & Cuadrado, A. Mar-2011 In : Molecular and Cellular Biology. 31, 6, p. 1121-1133, 13 p.

    Research output: Contribution to journal › Article

  5. Mechanism of Hypoxia-Induced NF-kappa B

    Culver, C., Sundqvist, A., Mudie, S., Melvin, A., Xirodimas, D. & Rocha, S. 10-Oct-2010 In : Molecular and Cellular Biology. 30, 20, p. 4901-4921, 21 p.

    Research output: Contribution to journal › Article

  6. miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo

    Leslie Pedrioli, D. M., Karpanen, T., Dabouras, V., Jurisic, G., Shin, J. W., Marino, D., Kälin, R. E., Brändli, A. W., Detmar, M., Van De Hoek, G., Schulte-Merker, S., Leidel, S. & Cinelli, P. Jul-2010 In : Molecular and Cellular Biology. 30, 14, p. 3620-3634, 15 p.

    Research output: Contribution to journal › Article

  7. SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na+-K+-Cl- cotransporter 2

    Reiche, J., Theilig, F., Rafiqi, F. H., Carlo, A-S., Militz, D., Mutig, K., Todiras, M., Christensen, E. I., Ellison, D. H., Bader, M., Nykjaer, A., Bachmann, S., Alessi, D. & Willnow, T. E. 15-Jun-2010 In : Molecular and Cellular Biology. 30, 12, p. 3027-3037, 11 p.

    Research output: Contribution to journal › Article

  8. S-Adenosyl Homocysteine Hydrolase Is Required for Myc-Induced mRNA Cap Methylation, Protein Synthesis, and Cell Proliferation

    Fernandez-Sanchez, M. E., Gonatopoulos-Pournatzis, T., Preston, G., Lawlor, M. A. & Cowling, V. H. 1-Dec-2009 In : Molecular and Cellular Biology. 29, 23, p. 6182-6191, 10 p.

    Research output: Contribution to journal › Article

  9. Phosphoinositide (3,4,5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation

    Waugh, C., Sinclair, L., Finlay, D., Bayascas, J. R. & Cantrell, D. 1-Nov-2009 In : Molecular and Cellular Biology. 29, 21, p. 5952-5962, 11 p.

    Research output: Contribution to journal › Article

  10. Efficient chromosome biorientation and the tension checkpoint in saccharomyces cerevisiae both require Bir1

    Makrantoni, V. & Stark, M. J. R. 15-Aug-2009 In : Molecular and Cellular Biology. 29, 16, p. 4552-4562, 11 p.

    Research output: Contribution to journal › Article

  11. SWI/SNF and Asf1p cooperate to displace histones during induction of the saccharomyces cerevisiae HO promoter

    Gkikopoulos, T., Havas, K. M., Dewar, H. & Owen-Hughes, T. Aug-2009 In : Molecular and Cellular Biology. 29, 15, p. 4057-4066, 10 p.

    Research output: Contribution to journal › Article

  12. Cholesterol Metabolism: the Main Pathway Acting Downstream of Cytochrome P450 Oxidoreductase in Skeletal Development of the Limb

    Schmidt, K., Hughes, C., Chudek, J. A., Goodyear, S. R., Aspden, R. M., Talbot, R., Gundersen, T. E., Blomhoff, R., Henderson, C., Wolf, C. R. & Tickle, C. 15-May-2009 In : Molecular and Cellular Biology. 29, 10, p. 2716-2729, 14 p.

    Research output: Contribution to journal › Article

  13. Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance

    Bayascas, J. R., Wullschleger, S., Sakamoto, K., Garcia-Martinez, J. M., Clacher, C., Komander, D., van Aalten, D. M. F., Boini, K. M., Lan, F., Lipina, C., Logie, L., Sutherland, C., Chudek, J. A., van Diepen, J. A., Voshol, P. J., Lucocq, J. M. & Alessi, D. R. May-2008 In : Molecular and Cellular Biology. 28, 10, p. 3258-3272, 15 p.

    Research output: Contribution to journal › Article

  14. Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IκBα kinase

    Windheim, M., Stafford, M., Cohen, P. & Peggie, M. Mar-2008 In : Molecular and Cellular Biology. 28, 5, p. 1783-1791, 9 p.

    Research output: Contribution to journal › Article

  15. c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1

    Cowling, V. H., D'Cruz, C. M., Chodosh, L. A. & Cole, M. D. 2007 In : Molecular and Cellular Biology. 27, 14, p. 5135-5146, 12 p.

    Research output: Contribution to journal › Article

  16. Histone tails and the H3 alphaN helix regulate nucleosome mobility and stability

    Ferreira, H., Somers, J., Webster, R., Flaus, A. & Owen-Hughes, T. 2007 In : Molecular and Cellular Biology. 27, 11, p. 4037-48, 12 p.

    Research output: Contribution to journal › Article

  17. The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding

    Cowling, V. H. & Cole, M. D. 2007 In : Molecular and Cellular Biology. 27, 6, p. 2059-2073, 15 p.

    Research output: Contribution to journal › Article

  18. UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination

    Alpi, A., Langevin, F., Mosedale, G., Machida, Y. J., Dutta, A. & Patel, K. J. 2007 In : Molecular and Cellular Biology. 27, 24, p. 8421-8430, 10 p.

    Research output: Contribution to journal › Article

  19. RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor

    Panov, K. I., Panova, T. B., Gadal, O., Nishiyama, K., Saito, T., Russell, J. & Zomerdijk, J. C. B. M. Jul-2006 In : Molecular and Cellular Biology. 26, 14, p. 5436-5448, 13 p.

    Research output: Contribution to journal › Article

  20. A conserved Myc protein domain, MBIV, regulates DNA binding, apoptosis, transformation, and G2 arrest

    Cowling, V. H., Chandriani, S., Whitfield, M. L. & Cole, M. D. Jun-2006 In : Molecular and Cellular Biology. 26, 11, p. 4226-4239, 14 p.

    Research output: Contribution to journal › Article

  21. Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes

    Matthews, S. A., Liu, P., Spitaler, M., Olson, E. N., McKinsey, T. A., Cantrell, D. A. & Scharenberg, A. M. Feb-2006 In : Molecular and Cellular Biology. 26, 4, p. 1569-1577, 9 p.

    Research output: Contribution to journal › Article

  22. Sialoadhesin-deficient mice exhibit subtle changes in B- and T-cell populations and reduced immunoglobulin M levels

    Oetke, C., Vinson, M. C., Jones, C. & Crocker, P. R. Feb-2006 In : Molecular and Cellular Biology. 26, 4, p. 1549-1557, 9 p.

    Research output: Contribution to journal › Article

  23. Casein kinase 2 associates with initiation-competent RNA polymerase I and has multiple roles in ribosomal DNA transcription

    Panova, T. B., Panov, K. I., Russell, J. & Zomerdijk, J. C. B. M. 2006 In : Molecular and Cellular Biology. 26, 16, p. 5957-5968, 12 p.

    Research output: Contribution to journal › Article

  24. Generation and characterization of p38beta (MAPK11) gene-targeted mice

    Beardmore, V. A., Hinton, H. J., Eftychi, C., Apostolaki, M., Armaka, M., Darragh, J., McIlrath, J., Carr, J. M., Armit, L. J., Clacher, C., Malone, L., Kollias, G. & Arthur, S. C. Dec-2005 In : Molecular and Cellular Biology. 25, 23, p. 10454-10464, 11 p.

    Research output: Contribution to journal › Article

  25. The dual-specificity protein phosphatase DUSP9/MKP-4 is essential for placental function but is not required for normal embryonic development

    Christie, G. R., Williams, D. J., MacIsaac, F., Dickinson, R. J., Rosewell, I. & Keyse, S. M. Sep-2005 In : Molecular and Cellular Biology. 25, 18, p. 8323-8333, 11 p.

    Research output: Contribution to journal › Article

  26. Mice with a disruption of the thrombospondin 3 gene differ in geometric and biomechanical properties of bone and have accelerated development of the femoral head

    Hankenson, K. D., Hormuzdi, S. G., Meganck, J. A. & Bornstein, P. 1-Jul-2005 In : Molecular and Cellular Biology. 25, 13, p. 5599-5606, 8 p.

    Research output: Contribution to journal › Article

  27. Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5

    Mandl, M., Slack, D. N. & Keyse, S. M. 2005 In : Molecular and Cellular Biology. 25, 5, p. 1830-1845, 16 p.

    Research output: Contribution to journal › Article

  28. Multiple genetic pathways involving the Caenorhabditis elegans Bloom's syndrome genes him-6, rad-51, and top-3 are needed to maintain genome stability in the germ line

    Wicky, C., Alpi, A., Passannante, M., Rose, A., Gartner, A. & Muller, F. 2004 In : Molecular and Cellular Biology. 24, 11, p. 5016-5027, 12 p.

    Research output: Contribution to journal › Article

  29. Identification of novel roles of the cytochrome P450 system in early embryogenesis: effects on vasculogenesis and retinoic acid homeostasis

    Otto, D. M. E., Henderson, C. J., Carrie, D., Davey, M., Gundersen, T. E., Blomhoff, R., Adams, R. H., Tickle, C. & Wolf, C. R. Sep-2003 In : Molecular and Cellular Biology. 23, 17, p. 6103-6116, 14 p.

    Research output: Contribution to journal › Article

  30. p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1

    Rocha, S., Martin, A. M., Meek, D. W. & Perkins, N. D. Jul-2003 In : Molecular and Cellular Biology. 23, 13, p. 4713-4727, 15 p.

    Research output: Contribution to journal › Article

  31. Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism

    Powell, D. J., Hajduch, E., Kular, G. & Hundal, H. S. H. 2003 In : Molecular and Cellular Biology. 23, 21, p. 7794-7808, 15 p.

    Research output: Contribution to journal › Article

  32. Dynamic properties of nucleosomes during thermal and ATP-driven mobilization

    Flaus, A. & Owen-Hughes, T. 2003 In : Molecular and Cellular Biology. 23, 21, p. 7767-7779, 13 p.

    Research output: Contribution to journal › Article

  33. Both binding and activation of p38 mitogen-activated protein kinase (MAPK) play essential roles in regulation of the nucleocytoplasmic distribution of MAPK-activated protein kinase 5 by cellular stress

    Seternes, O. M., Johansen, B., Hegge, B., Johannessen, M., Keyse, S. M. & Moens, U. Oct-2002 In : Molecular and Cellular Biology. 22, 20, p. 6931-45, 15 p.

    Research output: Contribution to journal › Article

  34. Hypophosphorylation of Mdm2 augments p53 stability

    Blattner, C., Hay, T., Meek, D. W. & Lane, D. P. Sep-2002 In : Molecular and Cellular Biology. 22, 17, p. 6170-6182, 13 p.

    Research output: Contribution to journal › Article

  35. MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts

    Wiggin, G. R., Soloaga, A., Foster, J. M., Murray-Tait, V., Cohen, P. & Arthur, J. S. C. Apr-2002 In : Molecular and Cellular Biology. 22, 8, p. 2871-2881, 11 p.

    Research output: Contribution to journal › Article

  36. UBF binding in vivo is not restricted to regulatory sequences within the vertebrate ribosomal DNA repeat

    O'Sullivan, A. C., Sullivan, G. J. & McStay, B. Jan-2002 In : Molecular and Cellular Biology. 22, 2, p. 657-668, 12 p.

    Research output: Contribution to journal › Article

  37. Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation

    Li, J., Gorospe, M., Hutter, D., Barnes, J., Keyse, S. M. & Liu, Y. Dec-2001 In : Molecular and Cellular Biology. 21, 23, p. 8213-24, 12 p.

    Research output: Contribution to journal › Article

  38. A step subsequent to preinitiation complex assembly at the ribosomal RNA gene promoter is rate limiting for human RNA polymerase I-dependent transcription

    Panov, K. I., Friedrich, J. K. & Zomerdijk, J. C. B. M. Apr-2001 In : Molecular and Cellular Biology. 21, 8, p. 2641-2649, 9 p.

    Research output: Contribution to journal › Article

  39. A gene-targeting approach identifies a function for the first intron in expression of the α1(I) collagen gene

    Hormuzdi, S. G., Penttinen, R., Jaenisch, R. & Bornstein, P. Jun-1998 In : Molecular and Cellular Biology. 18, 6, p. 3368-3375, 8 p.

    Research output: Contribution to journal › Article

  40. The Saccharomyces cerevisiae gene SDS22 encodes a potential regulator of the mitotic function of yeast type 1 protein phosphatase

    MACKELVIE, S. A. R. A. H. H., ANDREWS, P. A. U. L. D. & STARK, M. I. C. H. A. E. L. J. R. Jul-1995 In : Molecular and Cellular Biology. 15, 7, p. 3777-3785, 9 p.

    Research output: Contribution to journal › Article

  41. Two Saccharomyces cerevisiae genes which control sensitivity to G1 arrest induced by Kluyveromyces lactis toxin

    BUTLER, A. N. D. R. E. W. R., WHITE, J. O. H. N. H., FOLAWIYO, Y. E. T. U. N. D. E., EDLIN, A. N. G. E. L. A., GARDINER, D. O. N. A. L. D. & STARK, M. I. C. H. A. E. L. J. R. Sep-1994 In : Molecular and Cellular Biology. 14, 9, p. 6306-6316, 11 p.

    Research output: Contribution to journal › Article

  42. Inactivation of the protein phosphatase 2A regulatory subunit A results in morphological and transcriptional defects in Saccharomyces cerevisiae

    VANZYL, W. I. L. L. E. M., HUANG, W. E. I. D. O. N. G., SNEDDON, A. L. A. N. A., STARK, M. I. C. H. A. E. L., CAMIER, S. Y. L. V. I. E., WERNER, M. I. C. H. E. L., MARCK, C. H. R. I. S. T. I. A. N., SENTENAC, A. N. D. R. E. & BROACH, J. A. M. E. S. R. Nov-1992 In : Molecular and Cellular Biology. 12, 11, p. 4946-4959, 14 p.

    Research output: Contribution to journal › Article

  43. Oxidant stress leads to transcriptional activation of the human heme oxygenase gene in cultured skin fibroblasts

    Keyse, S. M., Applegate, L. A., Tromvoukis, Y. & Tyrrell, R. M. 1990 In : Molecular and Cellular Biology. 10, 9, p. 4967-9, 3 p.

    Research output: Contribution to journal › Article

  44. Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells

    Meek, D. W. & Eckhart, W. Jan-1988 In : Molecular and Cellular Biology. 8, 1, p. 461-465, 5 p.

    Research output: Contribution to journal › Article

  45. Determination of the spectrum of mutations induced by defined-wavelength solar UVB (313-nm) radiation in mammalian cells by use of a shuttle vector

    Keyse, S. M., Amaudruz, F. & Tyrrell, R. M. 1988 In : Molecular and Cellular Biology. 8, 12, p. 5425-31, 7 p.

    Research output: Contribution to journal › Article

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