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  1. MSK1 and MSK2 inhibit lipopolysaccharide-induced prostaglandin production via an interleukin-10 feedback loop

    MacKenzie, K. F., Van den Bosch, M. W. M., Naqvi, S., Elcombe, S. E., McGuire, V. A., Reith, A. D., Blackshear, P. J., Dean, J. L. E. & Arthur, J. S. C. Apr 2013 In : Molecular and Cellular Biology. 33, 7, p. 1456-1467 12 p.

    Research output: Contribution to journalArticle

  2. Cross talk between the Akt and p38α pathways in macrophages downstream of toll-like receptor signaling

    McGuire, V. A., Gray, A., Monk, C. E., Santos, S. G., Lee, K., Aubareda, A., Crowe, J., Ronkina, N., Schwermann, J., Batty, I. H., Leslie, N. R., Dean, J. L. E., O'Keefe, S. J., Boothby, M., Gaestel, M. & Arthur, J. S. C. 2013 In : Molecular and Cellular Biology. 33, 21, p. 4152-4165 14 p.

    Research output: Contribution to journalArticle

  3. Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP Axis

    Rada, P., Rojo, A. I., Evrard-Todeschi, N., Innamorato, N. G., Cotte, A., Jaworski, T., Tobón-Velasco, J. C., Devijver, H., García-Mayoral, M. F., Van Leuven, F., Hayes, J. D., Bertho, G. & Cuadrado, A. 2012 In : Molecular and Cellular Biology. 32, 17, p. 3486-99 14 p.

    Research output: Contribution to journalArticle

  4. Identification of RhoGAP22 as an Akt-dependent regulator of cell motility in response to insulin

    Rowland, A. F., Larance, M., Hughes, W. E. & James, D. E. Dec 2011 In : Molecular and Cellular Biology. 31, 23, p. 4789-4800 12 p.

    Research output: Contribution to journalArticle

  5. Contribution of casein kinase 2 and spleen tyrosine kinase to CFTR trafficking and protein kinase A-induced activity

    Luz, S., Kongsuphol, P., Mendes, A. I., Romeiras, F., Sousa, M., Schreiber, R., Matos, P., Jordan, P., Mehta, A., Amaral, M. D., Kunzelmann, K. & Farinha, C. M. Nov 2011 In : Molecular and Cellular Biology. 31, 22, p. 4392-4404 13 p.

    Research output: Contribution to journalArticle

  6. Elongator protein 3b negatively regulates ribosomal DNA transcription in African Trypanosomes

    Alsford, S. & Horn, D. May 2011 In : Molecular and Cellular Biology. 31, 9, p. 1822-1832 11 p.

    Research output: Contribution to journalArticle

  7. SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner

    Rada, P., Rojo, A. I., Chowdhry, S., McMahon, M., Hayes, J. D. & Cuadrado, A. Mar 2011 In : Molecular and Cellular Biology. 31, 6, p. 1121-1133 13 p.

    Research output: Contribution to journalArticle

  8. Mechanism of Hypoxia-Induced NF-kappa B

    Culver, C., Sundqvist, A., Mudie, S., Melvin, A., Xirodimas, D. & Rocha, S. 10 Oct 2010 In : Molecular and Cellular Biology. 30, 20, p. 4901-4921 21 p.

    Research output: Contribution to journalArticle

  9. miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo

    Leslie Pedrioli, D. M., Karpanen, T., Dabouras, V., Jurisic, G., Van De Hoek, G., Shin, J. W., Marino, D., Kälin, R. E., Leidel, S., Cinelli, P., Schulte-Merker, S., Brändli, A. W. & Detmar, M. Jul 2010 In : Molecular and Cellular Biology. 30, 14, p. 3620-3634 15 p.

    Research output: Contribution to journalArticle

  10. SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na+-K+-Cl- cotransporter 2

    Reiche, J., Theilig, F., Rafiqi, F. H., Carlo, A-S., Militz, D., Mutig, K., Todiras, M., Christensen, E. I., Ellison, D. H., Bader, M., Nykjaer, A., Bachmann, S., Alessi, D. & Willnow, T. E. 15 Jun 2010 In : Molecular and Cellular Biology. 30, 12, p. 3027-3037 11 p.

    Research output: Contribution to journalArticle

  11. S-Adenosyl Homocysteine Hydrolase Is Required for Myc-Induced mRNA Cap Methylation, Protein Synthesis, and Cell Proliferation

    Fernandez-Sanchez, M. E., Gonatopoulos-Pournatzis, T., Preston, G., Lawlor, M. A. & Cowling, V. H. 1 Dec 2009 In : Molecular and Cellular Biology. 29, 23, p. 6182-6191 10 p.

    Research output: Contribution to journalArticle

  12. Efficient chromosome biorientation and the tension checkpoint in saccharomyces cerevisiae both require Bir1

    Makrantoni, V. & Stark, M. J. R. 15 Aug 2009 In : Molecular and Cellular Biology. 29, 16, p. 4552-4562 11 p.

    Research output: Contribution to journalArticle

  13. SWI/SNF and Asf1p cooperate to displace histones during induction of the saccharomyces cerevisiae HO promoter

    Gkikopoulos, T., Havas, K. M., Dewar, H. & Owen-Hughes, T. Aug 2009 In : Molecular and Cellular Biology. 29, 15, p. 4057-4066 10 p.

    Research output: Contribution to journalArticle

  14. Cholesterol Metabolism: the Main Pathway Acting Downstream of Cytochrome P450 Oxidoreductase in Skeletal Development of the Limb

    Schmidt, K., Hughes, C., Chudek, J. A., Goodyear, S. R., Aspden, R. M., Talbot, R., Gundersen, T. E., Blomhoff, R., Henderson, C., Wolf, C. R. & Tickle, C. 15 May 2009 In : Molecular and Cellular Biology. 29, 10, p. 2716-2729 14 p.

    Research output: Contribution to journalArticle

  15. Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance

    Bayascas, J. R., Wullschleger, S., Sakamoto, K., Garcia-Martinez, J. M., Clacher, C., Komander, D., van Aalten, D. M. F., Boini, K. M., Lan, F., Lipina, C., Logie, L., Sutherland, C., Chudek, J. A., van Diepen, J. A., Voshol, P. J., Lucocq, J. M. & Alessi, D. R. May 2008 In : Molecular and Cellular Biology. 28, 10, p. 3258-3272 15 p.

    Research output: Contribution to journalArticle

  16. Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IκBα kinase

    Windheim, M., Stafford, M., Peggie, M. & Cohen, P. Mar 2008 In : Molecular and Cellular Biology. 28, 5, p. 1783-1791 9 p.

    Research output: Contribution to journalArticle

  17. Phosphorylation of Slx4 by Mec1 and Tel1 regulates the single-strand annealing mode of DNA repair in budding yeast

    Flott, S., Alabert, C., Toh, G. W., Toth, R., Sugawara, N., Campbell, D. G., Haber, J. E., Pasero, P. & Rouse, J. Sep 2007 In : Molecular and Cellular Biology. 27, 18, p. 6433-45 13 p.

    Research output: Contribution to journalArticle

  18. c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1

    Cowling, V. H., D'Cruz, C. M., Chodosh, L. A. & Cole, M. D. 2007 In : Molecular and Cellular Biology. 27, 14, p. 5135-5146 12 p.

    Research output: Contribution to journalArticle

  19. Histone tails and the H3 alphaN helix regulate nucleosome mobility and stability

    Ferreira, H., Somers, J., Webster, R., Flaus, A. & Owen-Hughes, T. 2007 In : Molecular and Cellular Biology. 27, 11, p. 4037-48 12 p.

    Research output: Contribution to journalArticle

  20. UBE2T, the Fanconi anemia core complex, and FANCD2 are recruited independently to chromatin: a basis for the regulation of FANCD2 monoubiquitination

    Alpi, A., Langevin, F., Mosedale, G., Machida, Y. J., Dutta, A. & Patel, K. J. 2007 In : Molecular and Cellular Biology. 27, 24, p. 8421-8430 10 p.

    Research output: Contribution to journalArticle

  21. RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor

    Panov, K. I., Panova, T. B., Gadal, O., Nishiyama, K., Saito, T., Russell, J. & Zomerdijk, J. C. B. M. Jul 2006 In : Molecular and Cellular Biology. 26, 14, p. 5436-5448 13 p.

    Research output: Contribution to journalArticle

  22. A conserved Myc protein domain, MBIV, regulates DNA binding, apoptosis, transformation, and G2 arrest

    Cowling, V. H., Chandriani, S., Whitfield, M. L. & Cole, M. D. Jun 2006 In : Molecular and Cellular Biology. 26, 11, p. 4226-4239 14 p.

    Research output: Contribution to journalArticle

  23. Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes

    Matthews, S. A., Liu, P., Spitaler, M., Olson, E. N., McKinsey, T. A., Cantrell, D. A. & Scharenberg, A. M. Feb 2006 In : Molecular and Cellular Biology. 26, 4, p. 1569-1577 9 p.

    Research output: Contribution to journalArticle

  24. Sialoadhesin-deficient mice exhibit subtle changes in B- and T-cell populations and reduced immunoglobulin M levels

    Oetke, C., Vinson, M. C., Jones, C. & Crocker, P. R. Feb 2006 In : Molecular and Cellular Biology. 26, 4, p. 1549-1557 9 p.

    Research output: Contribution to journalArticle

  25. Casein kinase 2 associates with initiation-competent RNA polymerase I and has multiple roles in ribosomal DNA transcription

    Panova, T. B., Panov, K. I., Russell, J. & Zomerdijk, J. C. B. M. 2006 In : Molecular and Cellular Biology. 26, 16, p. 5957-5968 12 p.

    Research output: Contribution to journalArticle

  26. Generation and characterization of p38beta (MAPK11) gene-targeted mice

    Beardmore, V. A., Hinton, H. J., Eftychi, C., Apostolaki, M., Armaka, M., Darragh, J., McIlrath, J., Carr, J. M., Armit, L. J., Clacher, C., Malone, L., Kollias, G. & Arthur, S. C. Dec 2005 In : Molecular and Cellular Biology. 25, 23, p. 10454-10464 11 p.

    Research output: Contribution to journalArticle

  27. The dual-specificity protein phosphatase DUSP9/MKP-4 is essential for placental function but is not required for normal embryonic development

    Christie, G. R., Williams, D. J., MacIsaac, F., Dickinson, R. J., Rosewell, I. & Keyse, S. M. Sep 2005 In : Molecular and Cellular Biology. 25, 18, p. 8323-8333 11 p.

    Research output: Contribution to journalArticle

  28. Mice with a disruption of the thrombospondin 3 gene differ in geometric and biomechanical properties of bone and have accelerated development of the femoral head

    Hankenson, K. D., Hormuzdi, S. G., Meganck, J. A. & Bornstein, P. 1 Jul 2005 In : Molecular and Cellular Biology. 25, 13, p. 5599-5606 8 p.

    Research output: Contribution to journalArticle

  29. Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5

    Mandl, M., Slack, D. N. & Keyse, S. M. 2005 In : Molecular and Cellular Biology. 25, 5, p. 1830-1845 16 p.

    Research output: Contribution to journalArticle

  30. Multiple genetic pathways involving the Caenorhabditis elegans Bloom's syndrome genes him-6, rad-51, and top-3 are needed to maintain genome stability in the germ line

    Wicky, C., Alpi, A., Passannante, M., Rose, A., Gartner, A. & Muller, F. 2004 In : Molecular and Cellular Biology. 24, 11, p. 5016-5027 12 p.

    Research output: Contribution to journalArticle

  31. Identification of novel roles of the cytochrome P450 system in early embryogenesis: effects on vasculogenesis and retinoic acid homeostasis

    Otto, D. M. E., Henderson, C. J., Carrie, D., Davey, M., Gundersen, T. E., Blomhoff, R., Adams, R. H., Tickle, C. & Wolf, C. R. Sep 2003 In : Molecular and Cellular Biology. 23, 17, p. 6103-6116 14 p.

    Research output: Contribution to journalArticle

  32. p53 represses cyclin D1 transcription through down regulation of Bcl-3 and inducing increased association of the p52 NF-kappaB subunit with histone deacetylase 1

    Rocha, S., Martin, A. M., Meek, D. W. & Perkins, N. D. Jul 2003 In : Molecular and Cellular Biology. 23, 13, p. 4713-4727 15 p.

    Research output: Contribution to journalArticle

  33. Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism

    Powell, D. J., Hajduch, E., Kular, G. & Hundal, H. S. H. 2003 In : Molecular and Cellular Biology. 23, 21, p. 7794-7808 15 p.

    Research output: Contribution to journalArticle

  34. Dynamic properties of nucleosomes during thermal and ATP-driven mobilization

    Flaus, A. & Owen-Hughes, T. 2003 In : Molecular and Cellular Biology. 23, 21, p. 7767-7779 13 p.

    Research output: Contribution to journalArticle

  35. Both binding and activation of p38 mitogen-activated protein kinase (MAPK) play essential roles in regulation of the nucleocytoplasmic distribution of MAPK-activated protein kinase 5 by cellular stress

    Seternes, O. M., Johansen, B., Hegge, B., Johannessen, M., Keyse, S. M. & Moens, U. Oct 2002 In : Molecular and Cellular Biology. 22, 20, p. 6931-45 15 p.

    Research output: Contribution to journalArticle

  36. Hypophosphorylation of Mdm2 augments p53 stability

    Blattner, C., Hay, T., Meek, D. W. & Lane, D. P. Sep 2002 In : Molecular and Cellular Biology. 22, 17, p. 6170-6182 13 p.

    Research output: Contribution to journalArticle

  37. MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts

    Wiggin, G. R., Soloaga, A., Foster, J. M., Murray-Tait, V., Cohen, P. & Arthur, J. S. C. Apr 2002 In : Molecular and Cellular Biology. 22, 8, p. 2871-2881 11 p.

    Research output: Contribution to journalArticle

  38. UBF binding in vivo is not restricted to regulatory sequences within the vertebrate ribosomal DNA repeat

    O'Sullivan, A. C., Sullivan, G. J. & McStay, B. Jan 2002 In : Molecular and Cellular Biology. 22, 2, p. 657-668 12 p.

    Research output: Contribution to journalArticle

  39. Transcriptional induction of MKP-1 in response to stress is associated with histone H3 phosphorylation-acetylation

    Li, J., Gorospe, M., Hutter, D., Barnes, J., Keyse, S. M. & Liu, Y. Dec 2001 In : Molecular and Cellular Biology. 21, 23, p. 8213-24 12 p.

    Research output: Contribution to journalArticle

  40. Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division

    Arthur, J. S. C., Elce, J. S., Hegadorn, C., Williams, K. & Greer, P. A. Jun 2000 In : Molecular and Cellular Biology. 20, 12, p. 4474-4481 8 p.

    Research output: Contribution to journalArticle

  41. A gene-targeting approach identifies a function for the first intron in expression of the α1(I) collagen gene

    Hormuzdi, S. G., Penttinen, R., Jaenisch, R. & Bornstein, P. Jun 1998 In : Molecular and Cellular Biology. 18, 6, p. 3368-3375 8 p.

    Research output: Contribution to journalArticle

  42. The Saccharomyces cerevisiae gene SDS22 encodes a potential regulator of the mitotic function of yeast type 1 protein phosphatase

    MACKELVIE, S. A. R. A. H. H., ANDREWS, P. A. U. L. D. & STARK, M. I. C. H. A. E. L. J. R. Jul 1995 In : Molecular and Cellular Biology. 15, 7, p. 3777-3785 9 p.

    Research output: Contribution to journalArticle

  43. Two Saccharomyces cerevisiae genes which control sensitivity to G1 arrest induced by Kluyveromyces lactis toxin

    BUTLER, A. N. D. R. E. W. R., WHITE, J. O. H. N. H., FOLAWIYO, Y. E. T. U. N. D. E., EDLIN, A. N. G. E. L. A., GARDINER, D. O. N. A. L. D. & STARK, M. I. C. H. A. E. L. J. R. Sep 1994 In : Molecular and Cellular Biology. 14, 9, p. 6306-6316 11 p.

    Research output: Contribution to journalArticle

  44. Inactivation of the protein phosphatase 2A regulatory subunit A results in morphological and transcriptional defects in Saccharomyces cerevisiae

    VANZYL, W. I. L. L. E. M., HUANG, W. E. I. D. O. N. G., SNEDDON, A. L. A. N. A., STARK, M. I. C. H. A. E. L., CAMIER, S. Y. L. V. I. E., WERNER, M. I. C. H. E. L., MARCK, C. H. R. I. S. T. I. A. N., SENTENAC, A. N. D. R. E. & BROACH, J. A. M. E. S. R. Nov 1992 In : Molecular and Cellular Biology. 12, 11, p. 4946-4959 14 p.

    Research output: Contribution to journalArticle

  45. Oxidant stress leads to transcriptional activation of the human heme oxygenase gene in cultured skin fibroblasts

    Keyse, S. M., Applegate, L. A., Tromvoukis, Y. & Tyrrell, R. M. 1990 In : Molecular and Cellular Biology. 10, 9, p. 4967-9 3 p.

    Research output: Contribution to journalArticle

  46. Phosphorylation of p53 in normal and simian virus 40-transformed NIH 3T3 cells

    Meek, D. W. & Eckhart, W. Jan 1988 In : Molecular and Cellular Biology. 8, 1, p. 461-465 5 p.

    Research output: Contribution to journalArticle

  47. Determination of the spectrum of mutations induced by defined-wavelength solar UVB (313-nm) radiation in mammalian cells by use of a shuttle vector

    Keyse, S. M., Amaudruz, F. & Tyrrell, R. M. 1988 In : Molecular and Cellular Biology. 8, 12, p. 5425-31 7 p.

    Research output: Contribution to journalArticle

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