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Molecular Microbiology

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  1. Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre

    Bellini, D., Caly, D. L., McCarthy, Y., Bumann, M., An, S-Q., Dow, J. M., Ryan, R. P. & Walsh, M. A. Jan 2014 In : Molecular Microbiology. 91, 1, p. 26-38 13 p.

    Research output: Contribution to journalArticle

  2. The PAS domain-containing histidine kinase RpfS is a second sensor for the diffusible signal factor of Xanthomonas campestris

    An, S-Q., Allan, J. H., McCarthy, Y., Febrer, M., Dow, J. M. & Ryan, R. P. 2014 In : Molecular Microbiology.

    Research output: Contribution to journalArticle

  3. Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy

    Ong, H. B., Sienkiewicz, N., Wyllie, S., Patterson, S. & Fairlamb, A. H. Oct 2013 In : Molecular Microbiology. 90, 2, p. 443-455 13 p.

    Research output: Contribution to journalArticle

  4. A mechanical signal transmitted by the flagellum controls signalling in Bacillus subtilis

    Cairns, L. S., Marlow, V. L., Bissett, E., Ostrowski, A. & Stanley-Wall, N. R. Oct 2013 In : Molecular Microbiology. 90, 1, p. 6-21 16 p.

    Research output: Contribution to journalArticle

  5. Signal peptide etiquette during assembly of a complex respiratory enzyme

    James, M. J., Coulthurst, S. J., Palmer, T. & Sargent, F. Oct 2013 In : Molecular Microbiology. 90, 2, p. 400-414 15 p.

    Research output: Contribution to journalArticle

  6. Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as an antifungal target

    Fang, W., Du, T., Raimi, O. G., Hurtado-Guerrero, R., Urbaniak, M. D., Ibrahim, A. F. M., Ferguson, M. A. J., Jin, C. & van Aalten, D. M. F. Aug 2013 In : Molecular Microbiology. 89, 3, p. 479-493 15 p.

    Research output: Contribution to journalArticle

  7. High-resolution transcriptional analysis of the regulatory influence of cell-to-cell signalling reveals novel genes that contribute to Xanthomonas phytopathogenesis

    An, S-Q., Febrer, M., McCarthy, Y., Tang, D-J., Clissold, L., Kaithakottil, G., Swarbreck, D., Tang, J-L., Rogers, J., Dow, J. M. & Ryan, R. P. Jun 2013 In : Molecular Microbiology. 88, 6, p. 1058-1069 12 p.

    Research output: Contribution to journalArticle

  8. The Escherichia coli SLC26 homologue YchM (DauA) is a C(4) -dicarboxylic acid transporter

    Karinou, E., Compton, E. L. R., Morel, M. & Javelle, A. Feb 2013 In : Molecular Microbiology. 87, 3, p. 623-640 18 p.

    Research output: Contribution to journalArticle

  9. Dynamic complex formation between HD-GYP, GGDEF and PilZ domain proteins regulates motility in Xanthomonas campestris

    Ryan, R. P., McCarthy, Y., Kiely, P. A., O'Connor, R., Farah, C. S., Armitage, J. P. & Dow, J. M. Nov 2012 In : Molecular Microbiology. 86, 3, p. 557-67 11 p.

    Research output: Contribution to journalArticle

  10. New secreted toxins and immunity proteins encoded within the type VI secretion system gene cluster of Serratia marcescens

    English, G., Trunk, K., Rao, V. A., Srikannathasan, V., Hunter, W. N. & Coulthurst, S. J. Nov 2012 In : Molecular Microbiology. 86, 4, p. 921-936 16 p.

    Research output: Contribution to journalArticle

  11. Chemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosome

    Jones, D. C., Alphey, M. S., Wyllie, S. & Fairlamb, A. H. Oct 2012 In : Molecular Microbiology. 86, 1, p. 51-64 14 p.

    Research output: Contribution to journalArticle

  12. Molecular dissection of TatC defines critical regions essential for protein transport and a TatB-TatC contact site

    Kneuper, H., Maldonado, B., Jäger, F., Buchanan, G., Keller, R., Palmer, T., Krehenbrink, M., Berks, B. C. & Müller, M. Sep 2012 In : Molecular Microbiology. 85, 5, p. 945-961 17 p.

    Research output: Contribution to journalArticle

  13. Inactivation of PbTopo III beta causes hyper-excision of the Pathogenicity Island HAI2 resulting in reduced virulence of Pectobacterium atrosepticum

    Vanga, B. R., Butler, R. C., Toth, I. K., Ronson, C. W. & Pitman, A. R. May 2012 In : Molecular Microbiology. 84, 4, p. 648-663 16 p.

    Research output: Contribution to journalArticle

  14. The de novo and salvage pathways of GDP-mannose biosynthesis are both sufficient for the growth of bloodstream-form Trypanosoma brucei

    Kuettel, S., Wadum, M. C. T., Guther, M. L. S., Marino, K., Riemer, C. & Ferguson, M. A. J. Apr 2012 In : Molecular Microbiology. 84, 2, p. 340-351 12 p.

    Research output: Contribution to journalArticle

  15. Overlapping transport and chaperone-binding functions within a bacterial twin-arginine signal peptide

    Grahl, S., Maillard, J., Spronk, C. A. E. M., Vuister, G. W. & Sargent, F. Mar 2012 In : Molecular Microbiology. 83, 6, p. 1254-1267 14 p.

    Research output: Contribution to journalArticle

  16. Phosphoglucomutase is absent in Trypanosoma brucei and redundantly substituted by phosphomannomutase and phospho-N-acetylglucosamine mutase

    Bandini, G., Marino, K., Güther, M. L. S., Wernimont, A. K., Kuettel, S., Qiu, W., Afzal, S., Kelner, A., Hui, R. & Ferguson, M. A. J. 2012 In : Molecular Microbiology. 85, 3, p. 513-534 22 p.

    Research output: Contribution to journalArticle

  17. Processing by rhomboid protease is required for Providencia stuartii TatA to interact with TatC and to form functional homo-oligomeric complexes

    Fritsch, M. J., Krehenbrink, M., Tarry, M. J., Berks, B. C. & Palmer, T. 2012 In : Molecular Microbiology. 84, 6, p. 1108-1123 16 p.

    Research output: Contribution to journalArticle

  18. Socializing, networking and development: A report from the second 'Young Microbiologists Symposium on Microbe Signalling, Organization and Pathogenesis'

    Caly, D. L., Coulthurst, S. J., Geoghegan, J. A., Malone, J. G. & Ryan, R. P. 2012 In : Molecular Microbiology. 86, 3, p. 501-512 12 p.

    Research output: Contribution to journalArticle

  19. The archetype Pseudomonas aeruginosa proteins TssB and TagJ form a novel subcomplex in the bacterial type VI secretion system

    Lossi, N. S., Manoli, E., Simpson, P., Jones, C., Hui, K., Dajani, R., Coulthurst, S. J., Freemont, P. & Filloux, A. 2012 In : Molecular Microbiology. 86, 2, p. 437-456 20 p.

    Research output: Contribution to journalArticle

  20. A multi-repeat adhesin of the phytopathogen, Pectobacterium atrosepticum, is secreted by a Type I pathway and is subject to complex regulation involving a non-canonical diguanylate cyclase

    Perez-Mendoza, D., Coulthurst, S. J., Humphris, S., Campbell, E., Welch, M., Toth, I. K. & Salmond, G. P. C. Nov 2011 In : Molecular Microbiology. 82, 3, p. 719-733 15 p.

    Research output: Contribution to journalArticle

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