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  1. Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains

    Kneuper, H., Cao, Z. P., Twomey, K. B., Zoltner, M., Jäger, F., Cargill, J. S., Chalmers, J., van der Kooi-Pol, M. M., van Dijl, J. M., Ryan, R. P., Hunter, W. N. & Palmer, T. Sep 2014 In : Molecular Microbiology. 93, 5, p. 928-943 15 p.

    Research output: Contribution to journalArticle

  2. Biofilm formation by Bacillus subtilis: new insights into regulatory strategies and assembly mechanisms

    Cairns, L. S., Hobley, L. & Stanley-Wall, N. R. Aug 2014 In : Molecular Microbiology. 93, 4, p. 587-598 12 p.

    Research output: Contribution to journalArticle

  3. A conserved and essential basic region mediates tRNA binding to the Elp1 subunit of the Saccharomyces cerevisiae Elongator complex

    Di Santo, R., Bandau, S. & Stark, M. J. R. Jun 2014 In : Molecular Microbiology. 92, 6, p. 1227-1242 16 p.

    Research output: Contribution to journalArticle

  4. The essential roles of cytidine diphosphate-diacylglycerol synthase in bloodstream form Trypanosoma brucei

    Lilley, A. C., Major, L., Young, S., Stark, M. J. R. & Smith, T. K. May 2014 In : Molecular Microbiology. 92, 3, p. 453-470 18 p.

    Research output: Contribution to journalArticle

  5. The PAS domain-containing histidine kinase RpfS is a second sensor for the diffusible signal factor of Xanthomonas campestris

    An, S-Q., Allan, J. H., McCarthy, Y., Febrer, M., Dow, J. M. & Ryan, R. P. May 2014 In : Molecular Microbiology. 92, 3, p. 586-597 12 p.

    Research output: Contribution to journalArticle

  6. Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre

    Bellini, D., Caly, D. L., McCarthy, Y., Bumann, M., An, S-Q., Dow, J. M., Ryan, R. P. & Walsh, M. A. Jan 2014 In : Molecular Microbiology. 91, 1, p. 26-38 13 p.

    Research output: Contribution to journalArticle

  7. Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy

    Ong, H. B., Sienkiewicz, N., Wyllie, S., Patterson, S. & Fairlamb, A. H. Oct 2013 In : Molecular Microbiology. 90, 2, p. 443-455 13 p.

    Research output: Contribution to journalArticle

  8. A mechanical signal transmitted by the flagellum controls signalling in Bacillus subtilis

    Cairns, L. S., Marlow, V. L., Bissett, E., Ostrowski, A. & Stanley-Wall, N. R. Oct 2013 In : Molecular Microbiology. 90, 1, p. 6-21 16 p.

    Research output: Contribution to journalArticle

  9. Signal peptide etiquette during assembly of a complex respiratory enzyme

    James, M. J., Coulthurst, S. J., Palmer, T. & Sargent, F. Oct 2013 In : Molecular Microbiology. 90, 2, p. 400-414 15 p.

    Research output: Contribution to journalArticle

  10. Genetic and structural validation of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as an antifungal target

    Fang, W., Du, T., Raimi, O. G., Hurtado-Guerrero, R., Urbaniak, M. D., Ibrahim, A. F. M., Ferguson, M. A. J., Jin, C. & van Aalten, D. M. F. Aug 2013 In : Molecular Microbiology. 89, 3, p. 479-493 15 p.

    Research output: Contribution to journalArticle

  11. High-resolution transcriptional analysis of the regulatory influence of cell-to-cell signalling reveals novel genes that contribute to Xanthomonas phytopathogenesis

    An, S-Q., Febrer, M., McCarthy, Y., Tang, D-J., Clissold, L., Kaithakottil, G., Swarbreck, D., Tang, J-L., Rogers, J., Dow, J. M. & Ryan, R. P. Jun 2013 In : Molecular Microbiology. 88, 6, p. 1058-1069 12 p.

    Research output: Contribution to journalArticle

  12. The Escherichia coli SLC26 homologue YchM (DauA) is a C(4) -dicarboxylic acid transporter

    Karinou, E., Compton, E. L. R., Morel, M. & Javelle, A. Feb 2013 In : Molecular Microbiology. 87, 3, p. 623-640 18 p.

    Research output: Contribution to journalArticle

  13. Determinants of substrate specificity and biochemical properties of the sn-glycerol-3-phosphate ATP binding cassette transporter (UgpB-AEC2) of Escherichia coli

    Wuttge, S., Bommer, M., Jager, F., Martins, B. M., Jacob, S., Licht, A., Scheffel, F., Dobbek, H. & Schneider, E. Nov 2012 In : Molecular Microbiology. 86, 4, p. 908-920 13 p.

    Research output: Contribution to journalArticle

  14. Dynamic complex formation between HD-GYP, GGDEF and PilZ domain proteins regulates motility in Xanthomonas campestris

    Ryan, R. P., McCarthy, Y., Kiely, P. A., O'Connor, R., Farah, C. S., Armitage, J. P. & Dow, J. M. Nov 2012 In : Molecular Microbiology. 86, 3, p. 557-67 11 p.

    Research output: Contribution to journalArticle

  15. New secreted toxins and immunity proteins encoded within the type VI secretion system gene cluster of Serratia marcescens

    English, G., Trunk, K., Rao, V. A., Srikannathasan, V., Hunter, W. N. & Coulthurst, S. J. Nov 2012 In : Molecular Microbiology. 86, 4, p. 921-936 16 p.

    Research output: Contribution to journalArticle

  16. Chemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosome

    Jones, D. C., Alphey, M. S., Wyllie, S. & Fairlamb, A. H. Oct 2012 In : Molecular Microbiology. 86, 1, p. 51-64 14 p.

    Research output: Contribution to journalArticle

  17. Molecular dissection of TatC defines critical regions essential for protein transport and a TatB-TatC contact site

    Kneuper, H., Maldonado, B., Jager, F., Buchanan, G., Keller, R., Palmer, T., Krehenbrink, M., Berks, B. C. & Müller, M. Sep 2012 In : Molecular Microbiology. 85, 5, p. 945-961 17 p.

    Research output: Contribution to journalArticle

  18. Inactivation of PbTopo III beta causes hyper-excision of the Pathogenicity Island HAI2 resulting in reduced virulence of Pectobacterium atrosepticum

    Vanga, B. R., Butler, R. C., Toth, I. K., Ronson, C. W. & Pitman, A. R. May 2012 In : Molecular Microbiology. 84, 4, p. 648-663 16 p.

    Research output: Contribution to journalArticle

  19. The de novo and salvage pathways of GDP-mannose biosynthesis are both sufficient for the growth of bloodstream-form Trypanosoma brucei

    Kuettel, S., Wadum, M. C. T., Guther, M. L. S., Marino, K., Riemer, C. & Ferguson, M. A. J. Apr 2012 In : Molecular Microbiology. 84, 2, p. 340-351 12 p.

    Research output: Contribution to journalArticle

  20. Overlapping transport and chaperone-binding functions within a bacterial twin-arginine signal peptide

    Grahl, S., Maillard, J., Spronk, C. A. E. M., Vuister, G. W. & Sargent, F. Mar 2012 In : Molecular Microbiology. 83, 6, p. 1254-1267 14 p.

    Research output: Contribution to journalArticle

  21. Phosphoglucomutase is absent in Trypanosoma brucei and redundantly substituted by phosphomannomutase and phospho-N-acetylglucosamine mutase

    Bandini, G., Marino, K., Güther, M. L. S., Wernimont, A. K., Kuettel, S., Qiu, W., Afzal, S., Kelner, A., Hui, R. & Ferguson, M. A. J. 2012 In : Molecular Microbiology. 85, 3, p. 513-534 22 p.

    Research output: Contribution to journalArticle

  22. Processing by rhomboid protease is required for Providencia stuartii TatA to interact with TatC and to form functional homo-oligomeric complexes

    Fritsch, M. J., Krehenbrink, M., Tarry, M. J., Berks, B. C. & Palmer, T. 2012 In : Molecular Microbiology. 84, 6, p. 1108-1123 16 p.

    Research output: Contribution to journalArticle

  23. Socializing, networking and development: A report from the second 'Young Microbiologists Symposium on Microbe Signalling, Organization and Pathogenesis'

    Caly, D. L., Coulthurst, S. J., Geoghegan, J. A., Malone, J. G. & Ryan, R. P. 2012 In : Molecular Microbiology. 86, 3, p. 501-512 12 p.

    Research output: Contribution to journalArticle

  24. The archetype Pseudomonas aeruginosa proteins TssB and TagJ form a novel subcomplex in the bacterial type VI secretion system

    Lossi, N. S., Manoli, E., Simpson, P., Jones, C., Hui, K., Dajani, R., Coulthurst, S. J., Freemont, P. & Filloux, A. 2012 In : Molecular Microbiology. 86, 2, p. 437-456 20 p.

    Research output: Contribution to journalArticle

  25. A multi-repeat adhesin of the phytopathogen, Pectobacterium atrosepticum, is secreted by a Type I pathway and is subject to complex regulation involving a non-canonical diguanylate cyclase

    Perez-Mendoza, D., Coulthurst, S. J., Humphris, S., Campbell, E., Welch, M., Toth, I. K. & Salmond, G. P. C. Nov 2011 In : Molecular Microbiology. 82, 3, p. 719-733 15 p.

    Research output: Contribution to journalArticle

  26. The CRP/FNR family protein Bcam1349 is a c-di-GMP effector that regulates biofilm formation in the respiratory pathogen Burkholderia cenocepacia

    Fazli, M., O'Connell, A., Nilsson, M., Niehaus, K., Dow, J. M., Givskov, M., Ryan, R. P. & Tolker-Nielsen, T. 1 Oct 2011 In : Molecular Microbiology. 82, 2, p. 327-341 15 p.

    Research output: Contribution to journalArticle

  27. Dissecting the complete lipoprotein biogenesis pathway in Streptomyces scabies

    Widdick, D. A., Hicks, M. G., Thompson, B. J., Tschumi, A., Chandra, G., Sutcliffe, I. C., Bruelle, J. K., Sander, P., Palmer, T. & Hutchings, M. I. Jun 2011 In : Molecular Microbiology. 80, 5, p. 1395-1412 18 p.

    Research output: Contribution to journalArticle

  28. A sensor kinase recognizing the cell-cell signal BDSF (cis-2-dodecenoic acid) regulates virulence in Burkholderia cenocepacia

    McCarthy, Y., Yang, L., Twomey, K. B., Sass, A., Tolker-Nielsen, T., Mahenthiralingam, E., Dow, J. M. & Ryan, R. P. Sep 2010 In : Molecular Microbiology. 77, 5, p. 1220-36 17 p.

    Research output: Contribution to journalArticle

  29. Histone deacetylases play distinct roles in telomeric VSG expression site silencing in African trypanosomes

    Wang, Q-P., Kawahara, T. & Horn, D. Sep 2010 In : Molecular Microbiology. 77, 5, p. 1237-1245 9 p.

    Research output: Contribution to journalArticle

  30. Investigating lipoprotein biogenesis and function in the model Gram-positive bacterium Streptomyces coelicolor

    Thompson, B. J., Widdick, D. A., Hicks, M. G., Chandra, G., Sutcliffe, I. C., Palmer, T. & Hutchings, M. I. Aug 2010 In : Molecular Microbiology. 77, 4, p. 943-957 15 p.

    Research output: Contribution to journalArticle

  31. Trypanosoma brucei pteridine reductase 1 is essential for survival in vitro and for virulence in mice

    Sienkiewicz, N., Ong, H. B. & Fairlamb, A. H. Aug 2010 In : Molecular Microbiology. 77, 3, p. 658-671 14 p.

    Research output: Contribution to journalArticle

  32. The twin arginine protein transport pathway exports multiple virulence proteins in the plant pathogen Streptomyces scabies

    Joshi, M. V., Mann, S. G., Antelmann, H., Widdick, D. A., Fyans, J. K., Chandra, G., Hutchings, M. I., Toth, I., Hecker, M., Loria, R. & Palmer, T. Jul 2010 In : Molecular Microbiology. 77, 1, p. 252-271 20 p.

    Research output: Contribution to journalArticle

  33. C-terminal amino acid residues of the trimeric autotransporter adhesin YadA of Yersinia enterocolitica are decisive for its recognition and assembly by BamA

    Lehr, U., Schuetz, M., Oberhettinger, P., Ruiz-Perez, F., Donald, J. W., Palmer, T., Linke, D., Henderson, I. R. & Autenrieth, I. B. 2010 In : Molecular Microbiology. 78, 4, p. 932-946 15 p.

    Research output: Contribution to journalArticle

  34. Post-translational control of Bacillus subtilis biofilm formation mediated by tyrosine phosphorylation

    Kiley, T. B. & Stanley-Wall, N. R. 2010 In : Molecular Microbiology. 78, 4, p. 947-963 17 p.

    Research output: Contribution to journalArticle

  35. Dissecting the essentiality of the bifunctional trypanothione synthetase-amidase in Trypanosoma brucei using chemical and genetic methods

    Wyllie, S., Oza, S. L., Patterson, S., Spinks, D., Thompson, S. & Fairlamb, A. H. Nov 2009 In : Molecular Microbiology. 74, 3, p. 529-540 12 p.

    Research output: Contribution to journalArticle

  36. Elongator function depends on antagonistic regulation by casein kinase Hrr25 and protein phosphatase Sit4

    Mehlgarten, C., Jablonowski, D., Breunig, K. D., Stark, M. J. R. & Schaffrath, R. Sep 2009 In : Molecular Microbiology. 73, 5, p. 869-881 13 p.

    Research output: Contribution to journalArticle

  37. Nurturing scientific mutualism: A report from the 'Young Microbiologists Mini-Symposium on microbe signalling, organisation and pathogenesis'

    Ryan, R. P., Romeo, T., De Keersmaecker, S. C. J. & Coulthurst, S. J. Sep 2009 In : Molecular Microbiology. 73, 5, p. 760-774 15 p.

    Research output: Contribution to journalArticle

  38. The ethanolamine branch of the Kennedy pathway is essential in the bloodstream form of Trypanosoma brucei

    Gibellini, F., Hunter, W. N. & Smith, T. K. Sep 2009 In : Molecular Microbiology. 73, 5, p. 826-843 18 p.

    Research output: Contribution to journalArticle

  39. Identification of a glycosylphosphatidylinositol anchor-modifying beta 1-3 N-acetylglucosaminyl transferase in Trypanosoma brucei

    Izquierdo, L., Nakanishi, M., Mehlert, A., Machray, G., Barton, G. J. & Ferguson, M. A. J. Jan 2009 In : Molecular Microbiology. 71, 2, p. 478-491 14 p.

    Research output: Contribution to journalArticle

  40. A versatile partner of eukaryotic protein complexes that is involved in multiple biological processes: Kti11/Dph3

    Baer, C., Zabel, R., Liu, S., Stark, M. J. R. & Schaffrath, R. Sep 2008 In : Molecular Microbiology. 69, 5, p. 1221-1233 13 p.

    Research output: Contribution to journalArticle

  41. Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes

    Kawahara, T., Siegel, T. N., Ingram, A. K., Alsford, S., Cross, G. A. M. & Horn, D. Aug 2008 In : Molecular Microbiology. 69, 4, p. 1054-1068 15 p.

    Research output: Contribution to journalArticle

  42. Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes

    Sienkiewicz, N., Jaroslawski, S., Wyllie, S. & Fairlamb, A. H. Jul 2008 In : Molecular Microbiology. 69, 2, p. 520-533 14 p.

    Research output: Contribution to journalArticle

  43. Fold and function of polypeptide transport-associated domains responsible for delivering unfolded proteins to membranes

    Knowles, T. J., Jeeves, M., Bobat, S., Dancea, F., McClelland, D., Palmer, T., Overduin, M. & Henderson, I. R. Jun 2008 In : Molecular Microbiology. 68, 5, p. 1216-1227 12 p.

    Research output: Contribution to journalArticle

  44. Control of the cell elongation-division cycle by shuttling of PBP1 protein in Bacillus subtilis

    Claessen, D., Emmins, R., Hamoen, L. W., Daniel, R. A., Errington, J. & Edwards, D. H. May 2008 In : Molecular Microbiology. 68, 4, p. 1029-1046 18 p.

    Research output: Contribution to journalArticle

  45. Acetylation of histone H4K4 is cell cycle regulated and mediated by HAT3 in Trypanosoma brucei

    Siegel, T. N., Kawahara, T., DeGrasse, J. A., Janzen, C. J., Horn, D. & Cross, G. A. M. Feb 2008 In : Molecular Microbiology. 67, 4, p. 762-771 10 p.

    Research output: Contribution to journalArticle

  46. Interspecies signalling via the Stenotrophomonas maltophilia diffusible signal factor influences biofilm formation and polymyxin tolerance in Pseudomonas aeruginosa

    Ryan, R. P., Fouhy, Y., Garcia, B. F., Watt, S. A., Niehaus, K., Yang, L., Tolker-Nielsen, T. & Dow, J. M. 2008 In : Molecular Microbiology. 68, 1, p. 75-86 12 p.

    Research output: Contribution to journalArticle

  47. DegU co-ordinates multicellular behaviour exhibited by Bacillus subtilis

    Verhamme, D., Kiley, T. B. & Stanley-Wall, N. R. Jul 2007 In : Molecular Microbiology. 65, 2, p. 554-568 15 p.

    Research output: Contribution to journalArticle

  48. A novel phospholipase from Trypanosoma brucei

    Richmond, G. S. & Smith, T. K. Feb 2007 In : Molecular Microbiology. 63, 4, p. 1078-95 18 p.

    Research output: Contribution to journalArticle

  49. Secretion by numbers: protein traffic in prokaryotes

    Economou, A., Christie, P. J., Fernandez, R. C., Palmer, T., Plano, G. V. & Pugsley, A. P. 2006 In : Molecular Microbiology. 62, 2, p. 308-319 12 p.

    Research output: Contribution to journalArticle

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