Molecular Pharmacology

Evidence that Cytochrome b5 and Cytochrome b5 Reductase Can Act as Sole Electron Donors to the Hepatic Cytochrome P450 System

Henderson, C. J., McLaughlin, L. A. & Wolf, C. R. Jun-2013 In : Molecular Pharmacology. 83, 6, p. 1209-1217, 9 p.

Research output: Contribution to journal › Article

Modeling Human Cytochrome P450 2D6 Metabolism and Drug-Drug Interaction by a Novel Panel of Knockout and Humanized Mouse Lines

Scheer, N., Kapelyukh, Y., McEwan, J., Beuger, V., Stanley, L. A., Rode, A. & Wolf, C. R. Jan-2012 In : Molecular Pharmacology. 81, 1, p. 63-72, 10 p.

Research output: Contribution to journal › Article

Quantitative Prediction of Human Pregnane X Receptor and Cytochrome P450 3A4 Mediated Drug-Drug Interaction in a Novel Multiple Humanized Mouse Line

Hasegawa, M., Kapelyukh, Y., Tahara, H., Seibler, J., Rode, A., Krueger, S., Lee, D. N., Wolf, C. R. & Scheer, N. Sep-2011 In : Molecular Pharmacology. 80, 3, p. 518-528, 11 p.

Research output: Contribution to journal › Article

Deletion of Microsomal Cytochrome b(5) Profoundly Affects Hepatic and Extrahepatic Drug Metabolism

McLaughlin, L. A., Ronseaux, S., Finn, R. D., Henderson, C. J. & Wolf, C. R. Aug-2010 In : Molecular Pharmacology. 78, 2, p. 269-278, 10 p.

Research output: Contribution to journal › Article

delta Receptors Are Required for Full Inhibitory Coupling of mu Receptors to Voltage-Dependent Ca2+ Channels in Dorsal Root Ganglion Neurons

Walwyn, W., John, S., Maga, M., Evans, C. J. & Hales, T. G. Jul-2009 In : Molecular Pharmacology. 76, 1, p. 134-143, 10 p.

Research output: Contribution to journal › Article

Direct subunit-dependent multimodal 5-hydroxytryptamine(3) receptor antagonism by methadone

Deeb, T. Z., Sharp, D. & Hales, T. G. Apr-2009 In : Molecular Pharmacology. 75, 4, p. 908-917, 10 p.

Research output: Contribution to journal › Article

An essential role for constitutive endocytosis, but not activity, in the axonal targeting of the CB1 cannabinoid receptor

McDonald, N. A., Henstridge, C. M., Connolly, C. N. & Irving, A. J. 2007 In : Molecular Pharmacology. 71, 4, p. 976-984, 9 p.

Research output: Contribution to journal › Article

Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways

Blackburn, A. C., Matthaei, K. I., Lim, C., Taylor, M. C., Cappello, J. Y., Hayes, J. D., Anders, M. W. & Board, P. G. 2006 In : Molecular Pharmacology. 69, 2, p. 650-7, 8 p.

Research output: Contribution to journal › Article

Proteasomal degradation of human CYP1B1: effect of the Asn453Ser polymorphism on the post-translational regulation of CYP1B1 expression

Bandiera, S., Weidlich, S., Harth, V., Broede, P., Ko, Y. & Friedberg, T. 2005 In : Molecular Pharmacology. 67, 2, p. 435-443, 9 p.

Research output: Contribution to journal › Article

Expression of the aflatoxin B1-8,9-epoxide-metabolizing murine glutathione S-transferase A3 subunit is regulated by the Nrf2 transcription factor through an antioxidant response element

Jowsey, I. R., Jiang, Q., Itoh, K., Yamamoto, M. & Hayes, J. D. 2003 In : Molecular Pharmacology. 64, 5, p. 1018-28, 11 p.

Research output: Contribution to journal › Article