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Molecular Pharmacology

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  1. Modeling Human Cytochrome P450 2D6 Metabolism and Drug-Drug Interaction by a Novel Panel of Knockout and Humanized Mouse Lines

    Scheer, N., Kapelyukh, Y., McEwan, J., Beuger, V., Stanley, L. A., Rode, A. & Wolf, C. R. Jan 2012 In : Molecular Pharmacology. 81, 1, p. 63-72 10 p.

    Research output: Contribution to journalArticle

  2. Quantitative Prediction of Human Pregnane X Receptor and Cytochrome P450 3A4 Mediated Drug-Drug Interaction in a Novel Multiple Humanized Mouse Line

    Hasegawa, M., Kapelyukh, Y., Tahara, H., Seibler, J., Rode, A., Krueger, S., Lee, D. N., Wolf, C. R. & Scheer, N. Sep 2011 In : Molecular Pharmacology. 80, 3, p. 518-528 11 p.

    Research output: Contribution to journalArticle

  3. Deletion of Microsomal Cytochrome b(5) Profoundly Affects Hepatic and Extrahepatic Drug Metabolism

    McLaughlin, L. A., Ronseaux, S., Finn, R. D., Henderson, C. J. & Wolf, C. R. Aug 2010 In : Molecular Pharmacology. 78, 2, p. 269-278 10 p.

    Research output: Contribution to journalArticle

  4. delta Receptors Are Required for Full Inhibitory Coupling of mu Receptors to Voltage-Dependent Ca2+ Channels in Dorsal Root Ganglion Neurons

    Walwyn, W., John, S., Maga, M., Evans, C. J. & Hales, T. G. Jul 2009 In : Molecular Pharmacology. 76, 1, p. 134-143 10 p.

    Research output: Contribution to journalArticle

  5. Direct subunit-dependent multimodal 5-hydroxytryptamine(3) receptor antagonism by methadone

    Deeb, T. Z., Sharp, D. & Hales, T. G. Apr 2009 In : Molecular Pharmacology. 75, 4, p. 908-917 10 p.

    Research output: Contribution to journalArticle

  6. An essential role for constitutive endocytosis, but not activity, in the axonal targeting of the CB1 cannabinoid receptor

    McDonald, N. A., Henstridge, C. M., Connolly, C. N. & Irving, A. J. 2007 In : Molecular Pharmacology. 71, 4, p. 976-984 9 p.

    Research output: Contribution to journalArticle

  7. Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways

    Blackburn, A. C., Matthaei, K. I., Lim, C., Taylor, M. C., Cappello, J. Y., Hayes, J. D., Anders, M. W. & Board, P. G. 2006 In : Molecular Pharmacology. 69, 2, p. 650-7 8 p.

    Research output: Contribution to journalArticle

  8. Proteasomal degradation of human CYP1B1: effect of the Asn453Ser polymorphism on the post-translational regulation of CYP1B1 expression

    Bandiera, S., Weidlich, S., Harth, V., Broede, P., Ko, Y. & Friedberg, T. 2005 In : Molecular Pharmacology. 67, 2, p. 435-443 9 p.

    Research output: Contribution to journalArticle

  9. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

    Inman, G. J., Nicolás, F. J., Callahan, J. F., Harling, J. D., Gaster, L. M., Reith, A. D., Laping, N. J. & Hill, C. S. 1 Jul 2002 In : Molecular Pharmacology. 62, 1, p. 65-74 10 p.

    Research output: Contribution to journalArticle

  10. Molecular cloning, genomic positioning, promoter identification, and characterization of the novel cyclic AMP-specific phosphodiesterase PDE4A10

    Rena, G., Begg, F., Ross, A., Mackenzie, C., Mcphee, I., Campbell, L., Huston, E., Sullivan, M. & Houslay, M. D. 2001 In : Molecular Pharmacology. 59, 5, p. 996-1011 16 p.

    Research output: Contribution to journalArticle

  11. Ciclazindol inhibits ATP-sensitive K+ channels and stimulates insulin secretion in CR1-G1 insulin-secreting cells

    Lee, K., Khan, R. N., Rowe, I. C., Ozanne, S. E., Hall, A. C., Papadakis, E., Hales, C. N. & Ashford, M. L. Apr 1996 In : Molecular Pharmacology. 49, 4, p. 715-20 6 p.

    Research output: Contribution to journalArticle

  12. Divergent regulation of cytochrome P450 enzymes by morphine and pethidine: a neuroendocrine mechanism?

    Rane, A., Liu, Z., Henderson, C. J. & Wolf, C. R. Jan 1995 In : Molecular Pharmacology. 47, 1, p. 57-64 8 p.

    Research output: Contribution to journalArticle

  13. The effects of trypsin on ATP-sensitive potassium channel properties and sulfonylurea receptors in the CRI-G1 insulin-secreting cell line

    Lee, K., Ozanne, S. E., Rowe, I. C. M., Hales, C. N. & Ashford, M. L. J. Jul 1994 In : Molecular Pharmacology. 46, 1, p. 176-185 10 p.

    Research output: Contribution to journalArticle

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