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Oncogene

  1. AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11

    Piscitello, D., Varshney, D., Lilla, S., Vizioli, M. G., Reid, C., Gorbunova, V., Seluanov, A., Gillespie, D. A. & Adams, P. D. 2 Oct 2017 In : Oncogene. 12 p.

    Research output: Contribution to journalArticle

  2. P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment

    Wada, M., Canals, D., Adada, M., Coant, N., Salama, M. F., Helke, K. L., Arthur, J. S., Shroyer, K. R., Kitatani, K., Obeid, L. M. & Hannun, Y. A. 7 Aug 2017 In : Oncogene.

    Research output: Contribution to journalArticle

  3. Mice deleted for cell division cycle 73 gene develop parathyroid and uterine tumours: model for the hyperparathyroidism-jaw tumour syndrome

    Walls, G. V., Stevenson, M., Lines, K. E., Newey, P. J., Reed, A. A. C., Bowl, M. R., Jeyabalan, J., Harding, B., Bradley, K. J., Manek, S., Chen, J., Wang, P. Z., Williams, B. O., Teh, B. T. & Thakker, R. V. 13 Jul 2017 In : Oncogene. 36, 28, p. 4025-4036 12 p.

    Research output: Contribution to journalArticle

  4. Crosstalk between NRF2 and HIPK2 shapes cytoprotective responses

    Torrente, L., Sanchez, C., Moreno Dorta, R., Chowdhry, S., Cabello, P., Isono, K., Koseki, H., Honda, T., Hayes, J., Dinkova-Kostova, A. & de la Vega, L. 10 Jul 2017 In : Oncogene.

    Research output: Contribution to journalArticle

  5. WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner

    Brown, K., Yang, P., Nobre Salvador, D., Kulikauskas, R., Ruohola-Baker, H., Robitaille, A. M., Chien, A. J., Moon, R. T. & Sherwood, V. 1 Jun 2017 In : Oncogene. 36, 22, p. 3119-3136 18 p.

    Research output: Contribution to journalArticle

  6. Inhibition of cholesterol metabolism underlies synergy between mTOR pathway inhibition and chloroquine in bladder cancer cells

    King, M. A., Ganley, I. G. & Flemington, V. 25 Aug 2016 In : Oncogene. 35, 34, p. 4518-4528 11 p.

    Research output: Contribution to journalArticle

  7. The heparan sulfate sulfotransferase 3-OST3A (HS3ST3A) is a novel tumor regulator and a prognostic marker in breast cancer

    Mao, X., Gauche, C., Coughtrie, M. W. H., Bui, C., Gulberti, S., Merhi-Soussi, F., Ramalanjaona, N., Bertin-Jung, I., Diot, A., Dumas, D., De Freitas Caires, N., Thompson, A. M., Bourdon, J-C., Ouzzine, M. & Fournel-Gigleux, S. 4 Apr 2016 In : Oncogene. 35, p. 5043-5055 13 p.

    Research output: Contribution to journalArticle

  8. The NEDD8 inhibitor MLN4924 increases the size of the nucleolus and activates p53 through the ribosomal-Mdm2 pathway

    Bailly, A., Perrin, A., Bou Malhab, L. J., Pion, E., Larance, M., Nagala, M., Smith, P., O'Donohue, M-F., Gleizes, P-E., Zomerdijk, J., Lamond, A. I. & Xirodimas, D. P. 28 Jan 2016 In : Oncogene. 35, 4, p. 415-426 12 p.

    Research output: Contribution to journalArticle

  9. PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally inhibiting the tumor-suppressor p53

    Wimmer, P., Berscheminski, J., Blanchette, P., Groitl, P., Branton, P. E., Hay, R. T., Dobner, T. & Schreiner, S. 7 Jan 2016 In : Oncogene. 35, p. 69-82 14 p.

    Research output: Contribution to journalArticle

  10. Prohibitin is required for transcriptional repression by the WT1-BASP1 complex

    Toska, E., Shandilya, J., Goodfellow, S. J., Medler, K. F. & Roberts, S. G. E. 23 Oct 2014 In : Oncogene. 33, 43, p. 5100-5108 9 p.

    Research output: Contribution to journalArticle

  11. The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.

    Sparks, A., Dayal, S., Das, J., Robertson, P., Menendez, S. & Saville, M. K. Oct 2014 In : Oncogene. 33, 38, p. 4685-4696 12 p.

    Research output: Contribution to journalArticle

  12. PDK1 controls upstream PI3K expression and PIP3 generation

    Dieterle, A. M., Böhler, P., Keppeler, H., Alers, S., Berleth, N., Drießen, S., Hieke, N., Pietkiewicz, S., Löffler, A. S., Peter, C., Gray, A., Leslie, N. R., Shinohara, H., Kurosaki, T., Engelke, M., Wienands, J., Bonin, M., Wesselborg, S. & Stork, B. 5 Jun 2014 In : Oncogene. 33, 23, p. 3043-3053 11 p.

    Research output: Contribution to journalArticle

  13. HIF-independent role of prolyl hydroxylases in the cellular response to amino acids

    Durán, R. V., Mackenzie, E. D., Boulahbel, H., Frezza, C., Heiserich, L., Tardito, S., Bussolati, O., Rocha, S., Hall, M. N. & Gottlieb, E. 19 Sep 2013 In : Oncogene. 32, 38, p. 4549-4556 8 p.

    Research output: Contribution to journalArticle

  14. The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage

    Nicol, S. M., Bray, S. E., Derek Black, H., Lorimore, S. A., Wright, E. G., Lane, D. P., Meek, D. W., Coates, P. J. & Fuller-Pace, F. V. 18 Jul 2013 In : Oncogene. 32, 29, p. 3461-3469 9 p.

    Research output: Contribution to journalArticle

  15. The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression

    Bernard, H., Garmy-Susini, B., Ainaoui, N., Van Den Berghe, L., Peurichard, A., Javerzat, S., Bikfalvi, A., Lane, D. P., Bourdon, J. C. & Prats, A-C. 25 Apr 2013 In : Oncogene. 32, 17, p. 2150-2160 11 p.

    Research output: Contribution to journalArticle

  16. p53 is activated in response to disruption of the pre-mRNA splicing machinery

    Allende-Vega, N., Dayal, S., Agarwala, U., Sparks, A., Bourdon, J-C. & Saville, M. K. 3 Jan 2013 In : Oncogene. 32, 1, p. 1-14 14 p.

    Research output: Contribution to journalArticle

  17. Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia

    Ånensen, N., Hjelle, S. M., Van Belle, W., Haaland, I., Silden, E., Bourdon, J-C., Hovland, R., Taskén, K., Knappskog, S., Lønning, P. E., Bruserud, O. & Gjertsen, B. T. 2012 In : Oncogene. 31, 12, p. 1533-1545 13 p.

    Research output: Contribution to journalArticle

  18. C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances

    Muller, P., Ruckova, E., Halada, P., Coates, P. J., Hrstka, R., Lane, D. P. & Vojtesek, B. 2012 In : Oncogene.

    Research output: Contribution to journalArticle

  19. Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

    Chowdhry, S., Zhang, Y., McMahon, M., Sutherland, C., Cuadrado, A. & Hayes, J. D. 2012 In : Oncogene. 32, p. 3765-3781 17 p.

    Research output: Contribution to journalArticle

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