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Oncogene

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  1. The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.

    Sparks, A., Dayal, S., Das, J., Robertson, P., Menendez, S. & Saville, M. K. 18 Sep 2014 In : Oncogene. 33, 38, p. 4685-4696 12 p.

    Research output: Contribution to journalArticle

  2. PDK1 controls upstream PI3K expression and PIP3 generation

    Dieterle, A. M., Böhler, P., Keppeler, H., Alers, S., Berleth, N., Drießen, S., Hieke, N., Pietkiewicz, S., Löffler, A. S., Peter, C., Gray, A., Leslie, N. R., Shinohara, H., Kurosaki, T., Engelke, M., Wienands, J., Bonin, M., Wesselborg, S. & Stork, B. 5 Jun 2014 In : Oncogene. 33, 23, p. 3043-3053 11 p.

    Research output: Contribution to journalArticle

  3. HIF-independent role of prolyl hydroxylases in the cellular response to amino acids

    Durán, R. V., Mackenzie, E. D., Boulahbel, H., Frezza, C., Heiserich, L., Tardito, S., Bussolati, O., Rocha, S., Hall, M. N. & Gottlieb, E. 19 Sep 2013 In : Oncogene. 32, 38, p. 4549-4556 8 p.

    Research output: Contribution to journalArticle

  4. The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage

    Nicol, S. M., Bray, S. E., Derek Black, H., Lorimore, S. A., Wright, E. G., Lane, D. P., Meek, D. W., Coates, P. J. & Fuller-Pace, F. V. 18 Jul 2013 In : Oncogene. 32, 29, p. 3461-3469 9 p.

    Research output: Contribution to journalArticle

  5. The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression

    Bernard, H., Garmy-Susini, B., Ainaoui, N., Van Den Berghe, L., Peurichard, A., Javerzat, S., Bikfalvi, A., Lane, D. P., Bourdon, J. C. & Prats, A-C. 25 Apr 2013 In : Oncogene. 32, 17, p. 2150-2160 11 p.

    Research output: Contribution to journalArticle

  6. p53 is activated in response to disruption of the pre-mRNA splicing machinery

    Allende-Vega, N., Dayal, S., Agarwala, U., Sparks, A., Bourdon, J-C. & Saville, M. K. 3 Jan 2013 In : Oncogene. 32, 1, p. 1-14 14 p.

    Research output: Contribution to journalArticle

  7. Prohibitin is required for transcriptional repression by the WT1-BASP1 complex

    Toska, E., Shandilya, J., Goodfellow, S. J., Medler, K. F. & Roberts, S. G. E. 2013 In : Oncogene.

    Research output: Contribution to journalArticle

  8. Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia

    Ånensen, N., Hjelle, S. M., Van Belle, W., Haaland, I., Silden, E., Bourdon, J-C., Hovland, R., Taskén, K., Knappskog, S., Lønning, P. E., Bruserud, O. & Gjertsen, B. T. 2012 In : Oncogene. 31, 12, p. 1533-1545 13 p.

    Research output: Contribution to journalArticle

  9. C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances

    Muller, P., Ruckova, E., Halada, P., Coates, P. J., Hrstka, R., Lane, D. P. & Vojtesek, B. 2012 In : Oncogene.

    Research output: Contribution to journalArticle

  10. Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

    Chowdhry, S., Zhang, Y., McMahon, M., Sutherland, C., Cuadrado, A. & Hayes, J. D. 2012 In : Oncogene. 32, p. 3765-3781 17 p.

    Research output: Contribution to journalArticle

  11. Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma

    Watt, S., Pourreyron, C., Purdie, K., Hogan, C., Cole, C. L., Foster, N., Pratt, N., Bourdon, J-C., Appleyard, V., Murray, K., Thompson, A., Mao, X., Mein, C., Bruckner-Tuderman, L., Evans, A., McGrath, J. A., Proby, C. M., Foerster, J., Leigh, I. & South, A. Nov 2011 In : Oncogene. 30, 46, p. 4666-4677 12 p.

    Research output: Contribution to journalArticle

  12. Absence of the Birt-Hogg-Dube gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility

    Preston, R. S., Philp, A., Claessens, T., Gijezen, L., Dydensborg, A. B., Dunlop, E. A., Harper, K. T., Brinkhuizen, T., Menko, F. H., Davies, D. M., Land, S. C., Pause, A., Baar, K., van Steensel, M. A. M. & Tee, A. R. 2011 In : Oncogene. 30, 10, p. 1159-1173 15 p.

    Research output: Contribution to journalArticle

  13. Cdc25B is negatively regulated by p53 through Sp1 and NF-Y transcription factors

    Dalvai, M., Mondesert, O., Bourdon, J-C., Ducommun, B. & Dozier, C. 2011 In : Oncogene. 30, 19, p. 2282-2288 7 p.

    Research output: Contribution to journalArticle

  14. Endoglin expression in breast tumor cells suppresses invasion and metastasis and correlates with improved clinical outcome

    Henry, L. A., Johnson, D. A., Sarrio, D., Lee, S., Quinlan, P. R., Crook, T., Thompson, A. M., Reis-Filho, J. S. & Isacke, C. M. 2011 In : Oncogene. 30, 9, p. 1046-1058 13 p.

    Research output: Contribution to journalArticle

  15. Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol

    Radulescu, S., Ridgway, R. A., Appleton, P., Kroboth, K., Patel, S., Woodgett, J., Taylor, S., Nathke, I. S. & Sansom, O. J. Dec 2010 In : Oncogene. 29, 49, p. 6418-6427 10 p.

    Research output: Contribution to journalArticle

  16. The RNA helicase p68 modulates expression and function of the Delta 133 isoform(s) of p53, and is inversely associated with Delta 133p53 expression in breast cancer

    Moore, H. C., Jordan, L. B., Bray, S. E., Baker, L., Quinlan, P. R., Purdie, C. A., Thompson, A. M., Bourdon, J-C. & Fuller-Pace, F. V. Dec 2010 In : Oncogene. 29, 49, p. 6475-6484 10 p.

    Research output: Contribution to journalArticle

  17. Enhanced mRNA cap methylation increases Cyclin D1 expression and promotes cell transformation

    Cowling, V. H. 11 Feb 2010 In : Oncogene. 29, 6, p. 930-936 7 p.

    Research output: Contribution to journalArticle

  18. Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN

    Davidson, L., Maccario, H., Perera, N. M., Yang, X., Spinelli, L., Tibarewal, P., Glancy, B., Gray, A., Weijer, C. J., Downes, C. P. & Leslie, N. R. 4 Feb 2010 In : Oncogene. 29, 5, p. 687-697 11 p.

    Research output: Contribution to journalArticle

  19. MdmX is a substrate for the deubiquitinating enzyme USP2a

    Allende-Vega, N., Sparks, A., Lane, D. P. & Saville, M. K. 21 Jan 2010 In : Oncogene. 29, 3, p. 432-441 10 p.

    Research output: Contribution to journalArticle

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