Organic and Biomolecular Chemistry

Diversity oriented syntheses of fused pyrimidines designed as potential antifolates

Gibson, C. L., Huggan, J. K., Kennedy, A., Kiefer, L., Lee, J. H., Suckling, C. J., Clements, C., Harvey, A. L., Hunter, W. N. & Tulloch, L. B. 2009 In : Organic and Biomolecular Chemistry. 7, 9, p. 1829-1842, 14 p.

Research output: Contribution to journal › Article

Novel functionalized melamine-based nitroheterocycles: synthesis and activity against trypanosomatid parasites

Baliani, A., Peal, V., Gros, L., Brun, R., Kaiser, M., Barrett, M. P. & Gilbert, I. H. 2009 In : Organic and Biomolecular Chemistry. 7, 6, p. 1154-1166, 13 p.

Research output: Contribution to journal › Article

Solid-phase synthesis of cyclic peptide chitinase inhibitors: SAR of the argifin scaffold

Dixon, M. J., Nathubhai, A., Andersen, O. A., van Aalten, D. M. F. & Eggleston, I. M. 2009 In : Organic and Biomolecular Chemistry. 7, 2, p. 259-268, 10 p.

Research output: Contribution to journal › Article

Inhibitors of the kinase IspE: structure-activity relationships and co-crystal structure analysis

Hirsch, A. K. H., Alphey, M. S., Lauw, S., Seet, M., Barandun, L., Eisenreich, W., Rohdich, F., Hunter, W. N., Bacher, A. & Diederich, F. 2008 In : Organic and Biomolecular Chemistry. 6, 15, p. 2719-2730, 12 p.

Research output: Contribution to journal › Article

The small molecule tool (S)-(-)-blebbistatin: novel insights of relevance to myosin inhibitor design

Lucas-Lopez, C., Allingham, J. S., Lebl, T., Lawson, C. P. A. T., Brenk, R., Sellers, J. R., Rayment, I. & Westwood, N. J. 2008 In : Organic and Biomolecular Chemistry. 6, 12, p. 2076-2084, 9 p.

Research output: Contribution to journal › Article

Sensing of remote oxyanion binding at the DNA binding domain of the molybdate-dependent transcriptional regulator, ModE

Boxer, D. H., Zhang, H., Gourley, D. G., Hunter, W. N., Kelly, S. M. & Price, N. C. 2004 In : Organic and Biomolecular Chemistry. 2, 19, p. 2829-2837, 9 p.

Research output: Contribution to journal › Article

Synthesis of (R)-2-methyl-4-deoxy and (R)-2-methyl-4,5-dideoxy analogues of 6-phosphogluconate as potential inhibitors of 6-phosphogluconate dehydrogenase

Dardonville, C. & Gilbert, I. H. 2003 In : Organic and Biomolecular Chemistry. 1, 3, p. 552-559, 8 p.

Research output: Contribution to journal › Article