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Pharmacogenetics and Genomics

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  1. Robust association of the LPA locus with low-density lipoprotein cholesterol lowering response to statin treatment in a meta-analysis of 30 467 individuals from both randomized control trials and observational studies and association with coronary artery disease outcome during statin treatment

    Donnelly, L. A., van Zuydam, N. R., Zhou, K., Tavendale, R., Carr, F., Maitland-van der Zee, A. H., Leusink, M., de Boer, A., Doevendans, P. A., Asselbergs, F. W., Morris, A. D., Pearson, E. R., Klungel, O. H., Doney, A. S. F. & Palmer, C. N. A. 2013 In : Pharmacogenetics and Genomics. 23, 10, p. 518-525 8 p.

    Research output: Contribution to journalArticle

  2. Glutathione S-transferase M1 (GSTM1) genotype but not GSTT1 or MC1R genotype influences erythemal sensitivity to narrow band (TL-01) UVB phototherapy

    Smith, G., Weidlich, S., Dawe, R. S. & Ibbotson, S. H. Apr 2011 In : Pharmacogenetics and Genomics. 21, 4, p. 217-224 8 p.

    Research output: Contribution to journalArticle

  3. Polymorphisms in xenobiotic metabolizing enzymes and diet influence colorectal adenoma risk

    Northwood, E. L., Elliott, F., Forman, D., Barrett, J. H., Wilkie, M. J. V., Carey, F. A., Steele, R. J. C., Wolf, R., Bishop, T. & Smith, G. 2010 In : Pharmacogenetics and Genomics. 20, 5, p. 315-326 12 p.

    Research output: Contribution to journalArticle

  4. Nomenclature for alleles of the cytochrome P450 oxidoreductase gene

    Sim, S. C., Miller, W. L., Zhong, X-B., Arlt, W., Ogata, T., Ding, X., Wolf, C. R., Flueck, C. E., Pandey, A. V., Henderson, C. J., Porter, T. D., Daly, A. K., Nebert, D. W. & Ingelman-Sundberg, M. 2009 In : Pharmacogenetics and Genomics. 19, 7, p. 565-566 2 p.

    Research output: Contribution to journalLetter

  5. A paucimorphic variant in the HMO-CoA reductase gene is associated with lipid-lowering response to statin treatment in diabetes: a GoDARTS study

    Donnelly, L. A., Doney, A. S. F., Dannfald, J., Whitley, A. L., Lang, C. C., Morris, A. D., Donnan, P. T. & Palmer, C. N. A. Dec 2008 In : Pharmacogenetics and Genomics. 18, 12, p. 1021-1026 6 p.

    Research output: Contribution to journalArticle

  6. Characterization of the effects of four HTR3B polymorphisms an human 5-HT3AB receptor expression and signalling

    Krzywkowski, K., Davies, P. A., Irving, A. J., Brauner-Osborne, H. & Jensen, A. A. Dec 2008 In : Pharmacogenetics and Genomics. 18, 12, p. 1027-1040 14 p.

    Research output: Contribution to journalArticle

  7. Apolipoprotein E genotypes are associated with lipid-lowering responses to statin treatment in diabetes: a Go-DARTS study

    Donnelly, L. A., Palmer, C. N. A., Whitley, A. L., Lang, C. C., Doney, A. S. F., Morris, A. D. & Donnan, P. T. Apr 2008 In : Pharmacogenetics and Genomics. 18, 4, p. 279-287 9 p.

    Research output: Contribution to journalArticle

  8. Naturally occurring variations in the human 5-HT3A gene profoundly impact 5-HT3 receptor function and expression

    Krzywkowski, K., Jensen, A. A., Connolly, C. N. & Brauner-Osborne, H. Apr 2007 In : Pharmacogenetics and Genomics. 17, 4, p. 255-266 12 p.

    Research output: Contribution to journalArticle

  9. A splice site polymorphism in the G-protein beta subunit influences antidepressant efficacy in depression

    Wilkie, M. J. V., Smith, D., Reid, I. C., Day, R. K., Matthews, K., Wolf, R., Blackwood, D. & Smith, G. Mar 2007 In : Pharmacogenetics and Genomics. 17, 3, p. 207-215 9 p.

    Research output: Contribution to journalArticle

  10. No evidence that polymorphisms in CYP2C8, CYP2C9, UGT1A6, PPAR[delta] and PPAR[gamma] act as modifiers of the protective effect of regular NSAID use on the risk of colorectal carcinoma

    McGreavey, L. E., Turner, F., Smith, G., Boylan, K., Bishop, D. T., Forman, D., Wolf, C. R. & Barrett, J. H. 2005 In : Pharmacogenetics and Genomics. 15, 10, p. 713-721 9 p.

    Research output: Contribution to journalArticle

  11. Phenol sulphotransferase SULT1A1*1 genotype is associated with reduced risk of colorectal cancer

    Bamber, D. E., Fryer, A. A., Strange, R. C., Elder, J. B., Deakin, M., Rajagopal, R., Fawole, A., Gilissen, R. A. H. J., Campbell, F. C. & Coughtrie, M. W. H. 2001 In : Pharmacogenetics and Genomics. 11, 8, p. 679-685 7 p.

    Research output: Contribution to journalArticle

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