PLoS Genetics

The amidation step of Diphthamide biosynthesis in yeast requires DPH6, a gene identified through mining the DPH1-DPH5 interaction network

Uthman, S., Baer, C., Scheidt, V., Liu, S., Ten Have, S., Giorgini, F., Stark, M. J. R. & Schaffrath, R. 2013 In : PLoS Genetics. 9, 2, e1003334

Research output: Contribution to journal › Article

New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes

Sandholm, N. , Salem, R. M. , McKnight, A. J. , Brennan, E. P. , Forsblom, C. , Isakova, T. , McKay, G. J. , Williams, W. W. , Sadlier, D. M. , Makinen, V-P. , Swan, E. J. , Palmer, C. , Boright, A. P. , Ahlqvist, E. , Deshmukh, H. A. , Keller, B. J. , Huang, H. , Ahola, A. J. , Fagerholm, E. , Gordin, D. & 73 others Harjutsalo, V., He, B., Heikkila, O., Hietala, K., Kyto, J., Lahermo, P., Lehto, M., Lithovius, R., Osterholm, A-M., Parkkonen, M., Pitkaniemi, J., Rosengard-Barlund, M., Saraheimo, M., Sarti, C., Soderlund, J., Soro-Paavonen, A., Syreeni, A., Thorn, L. M., Tikkanen, H., Tolonen, N., Tryggvason, K., Tuomilehto, J., Waden, J., Gill, G. V., Prior, S., Guiducci, C., Mirel, D. B., Taylor, A., Hosseini, S. M., Parving, H-H., Rossing, P., Tarnow, L., Ladenvall, C., Alhenc-Gelas, F., Lefebvre, P., Rigalleau, V., Roussel, R., Tregouet, D-A., Maestroni, A., Maestroni, S., Falhammar, H., Gu, T., Mollsten, A., Cimponeriu, D., Ioana, M., Mota, M., Mota, E., Serafinceanu, C., Stavarachi, M., Hanson, R. L., Nelson, R. G., Kretzler, M., Colhoun, H. M., Panduru, N. M., Gu, H. F., Brismar, K., Zerbini, G., Hadjadj, S., Marre, M., Groop, L., Lajer, M., Bull, S. B., Waggott, D., Paterson, A. D., Savage, D. A., Bain, S. C., Martin, F., Hirschhorn, J. N., Godson, C., Florez, J. C., Groop, P-H., Maxwell, A. P. & DCCT-EDIC Res Grp 20-Sep-2012 In : PLoS Genetics. 8, 9, 13 p., e1002921

Research output: Contribution to journal › Article

Raf1 is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modification

Buscaino, A., White, S. A., Houston, D. R., Lejeune, E., Simmer, F., de Lima Alves, F., Diyora, P. T., Bayne, E. H., Rappsilber, J., Allshire, R. C. & Urano, T. 1-Feb-2012 In : PLoS Genetics. 8, 2, e1002499

Research output: Contribution to journal › Article

Combining Comparative Proteomics and Molecular Genetics Uncovers Regulators of Synaptic and Axonal Stability and Degeneration In Vivo

Wishart, T. M., Rooney, T. M., Lamont, D. J., Wright, A. K., Morton, A. J., Jackson, M., Freeman, M. R. & Gillingwater, T. H. 2012 In : PLoS Genetics. 8, 8

Research output: Contribution to journal › Article

Genome-wide association and functional follow-up reveals new loci for kidney function

Pattaro, C. , Koettgen, A. , Teumer, A. , Garnaas, M. , Boeger, C. A. , Fuchsberger, C. , Olden, M. , Chen, M-H. , Tin, A. , Taliun, D. , Li, M. , Gao, X. , Gorski, M. , Yang, Q. , Hundertmark, C. , Foster, M. C. , O'Seaghdha, C. M. , Glazer, N. , Isaacs, A. , Liu, C-T. & 147 others Smith, A. V., O'Connell, J. R., Struchalin, M., Tanaka, T., Li, G., Johnson, A. D., Gierman, H. J., Feitosa, M., Hwang, S-J., Atkinson, E. J., Lohman, K., Cornelis, M. C., Johansson, A., Toenjes, A., Dehghan, A., Chouraki, V., Holliday, E. G., Sorice, R., Kutalik, Z., Lehtimaeki, T., Esko, T., Deshmukh, H., Ulivi, S., Chu, A. Y., Murgia, F., Trompet, S., Imboden, M., Kollerits, B., Pistis, G., Harris, T. B., Launer, L. J., Aspelund, T., Eiriksdottir, G., Mitchell, B. D., Boerwinkle, E., Schmidt, H., Cavalieri, M., Rao, M., Hu, F. B., Demirkan, A., Oostra, B. A., de Andrade, M., Turner, S. T., Ding, J., Andrews, J. S., Freedman, B. I., Koenig, W., Illig, T., Doering, A., Wichmann, H. -E., Kolcic, I., Zemunik, T., Boban, M., Minelli, C., Wheeler, H. E., Igl, W., Zaboli, G., Wild, S. H., Wright, A. F., Campbell, H., Ellinghaus, D., Nothlings, U., Jacobs, G., Biffar, R., Endlich, K., Ernst, F., Homuth, G., Kroemer, H. K., Nauck, M., Stracke, S., Voelker, U., Voelzke, H., Kovacs, P., Stumvoll, M., Magi, R., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Aulchenko, Y. S., Polasek, O., Hastie, N., Vitart, V., Helmer, C., Wang, J. J., Ruggiero, D., Bergmann, S., Kaehoenen, M., Viikari, J., Nikopensius, T., Province, M., Ketkar, S., Colhoun, H., Doney, A., Robino, A., Giulianini, F., Kraemer, B. K., Portas, L., Ford, I., Buckley, B. M., Adam, M., Thun, G-A., Paulweber, B., Haun, M., Sala, C., Metzger, M., Mitchell, P., Ciullo, M., Kim, S. K., Vollenweider, P., Raitakari, O., Metspalu, A., Palmer, C., Gasparini, P., Pirastu, M., Jukema, J. W., Probst-Hensch, N. M., Kronenberg, F., Toniolo, D., Gudnason, V., Shuldiner, A. R., Coresh, J., Schmidt, R., Ferrucci, L., Siscovick, D. S., van Duijn, C. M., Borecki, I., Kardia, S. L. R., Liu, Y., Curhan, G. C., Rudan, I., Gyllensten, U., Wilson, J. F., Franke, A., Pramstaller, P. P., Rettig, R., Prokopenko, I., Witteman, J. C. M., Hayward, C., Ridker, P., Parsa, A., Bochud, M., Heid, I. M., Goessling, W., Chasman, D. I., Kao, W. H. L., Fox, C. S. & WTCCC2, CARDIoGRAM Consortium, CARe Consortium, ICBP Consortium 2012 In : PLoS Genetics. 8, 3, p. -, 15 p., e1002584

Research output: Contribution to journal › Article

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

Perry, J. R. B. , Voight, B. F. , Yengo, L. , Amin, N. , Dupuis, J. , Ganser, M. , Grallert, H. , Navarro, P. , Li, M. , Qi, L. , Steinthorsdottir, V. , Scott, R. A. , Almgren, P. , Arking, D. E. , Aulchenko, Y. , Balkau, B. , Benediktsson, R. , Bergman, R. N. , Boerwinkle, E. , Bonnycastle, L. & 56 others Burtt, N. P., Campbell, H., Charpentier, G., Collins, F. S., Gieger, C., Green, T., Hadjadj, S., Hattersley, A. T., Herder, C., Hofman, A., Johnson, A. D., Kottgen, A., Kraft, P., Labrune, Y., Langenberg, C., Manning, A. K., Mohlke, K. L., Morris, A. P., Oostra, B., Pankow, J., Petersen, A-K., Pramstaller, P. P., Prokopenko, I., Rathmann, W., Rayner, W., Roden, M., Rudan, I., Rybin, D., Scott, L. J., Sigurdsson, G., Sladek, R., Thorleifsson, G., Thorsteinsdottir, U., Tuomilehto, J., Uitterlinden, A. G., Vivequin, S., Weedon, M. N., Wright, A. F., Hu, F. B., Illig, T., Kao, L., Meigs, J. B., Wilson, J. F., Stefansson, K., van Duijn, C., Altschuler, D., Morris, A. D., Boehnke, M., McCarthy, M. I., Froguel, P., Palmer, C. N. A., Wareham, N. J., Groop, L., Frayling, T. M., Cauchi, S. & GIANT Consortium, DIAGRAM Consortium, MAGIC 2012 In : PLoS Genetics. 8, 5, p. -, 14 p., e1002741

Research output: Contribution to journal › Article

Regulation of Caenorhabditis elegans p53/CEP-1-Dependent Germ Cell Apoptosis by Ras/MAPK Signaling

Rutkowski, R., Dickinson, R., Stewart, G., Craig, A., Schimpl, M., Keyse, S. M. & Gartner, A. Aug-2011 In : PLoS Genetics. 7, 8, p. -, 21 p., e1002238

Research output: Contribution to journal › Article

Association between Common Variation at the FTO Locus and Changes in Body Mass Index from Infancy to Late Childhood: The Complex Nature of Genetic Association through Growth and Development

Sovio, U. , Mook-Kanamori, D. O. , Warrington, N. M. , Lawrence, R. , Briollais, L. , Palmer, C. N. A. , Cecil, J. , Sandling, J. K. , Syvanen, A-C. , Kaakinen, M. , Beilin, L. J. , Millwood, I. Y. , Bennett, A. J. , Laitinen, J. , Pouta, A. , Molitor, J. , Smith, G. D. , Ben-Shlomo, Y. , Jaddoe, V. W. V. , Palmer, L. J. & 6 others Pennell, C. E., Cole, T. J., McCarthy, M. I., Jarvelin, M-R., Timpson, N. J. & Early Growth Genetics Consortium Feb-2011 In : PLoS Genetics. 7, 2, p. -, 13 p., e1001307

Research output: Contribution to journal › Article

Evolutionary conserved regulation of HIF-1 beta by NF-kappa B

van Uden, P., Kenneth, N. S., Webster, R., Muller, H. A., Mudie, S. & Rocha, S. Jan-2011 In : PLoS Genetics. 7, 1, p. -, 15 p., e1001285

Research output: Contribution to journal › Article

Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension

Padmanabhan, S. , Melander, O. , Johnson, T. , Di Blasio, A. M. , Lee, W. K. , Gentilini, D. , Hastie, C. E. , Menni, C. , Monti, M. C. , Delles, C. , Laing, S. , Corso, B. , Navis, G. , Kwakernaak, A. J. , van der Harst, P. , Bochud, M. , Maillard, M. , Burnier, M. , Hedner, T. , Kjeldsen, S. & 54 others Wahlstrand, . B., Sjogren, M., Fava, C., Montagnana, M., Danese, E., Torffvit, O., Hedblad, B., Snieder, H., Connell, J. M. C., Brown, M., Samani, N. J., Farrall, M., Cesana, G., Mancia, G., Signorini, S., Grassi, G., Eyheramendy, S., Wichmann, H. E., Laan, M., Strachan, D. P., Sever, P., Shields, D. C., Stanton, A., Vollenweider, P., Teumer, A., Voelzke, H., Rettig, R., Newton-Cheh, C., Arora, P., Zhang, F., Soranzo, N., Spector, T. D., Lucas, G., Kathiresan, S., Siscovick, D. S., Luan, J., Loos, R. J. F., Wareham, N. J., Penninx, B. W., Nolte, I. M., McBride, M., Miller, W. H., Nicklin, S. A., Baker, A. H., Graham, D., McDonald, R. A., Pell, J. P., Sattar, N., Welsh, P., Munroe, P., Caulfield, M. J., Zanchetti, A., Dominiczak, A. F. & Global BPgen Consortium Oct-2010 In : PLoS Genetics. 6, 10, p. -, 11 p., e1001177

Research output: Contribution to journal › Article