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Proceedings of the National Academy of Sciences of the United States of America

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  1. Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions

    Ismail, H. M., O'Neill, P. M., Hong, D. W., Finn, R. D., Henderson, C. J., Wright, A. T., Cravatt, B. F., Hemingway, J. & Paine, M. J. I. 3 Dec 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 49, p. 19766-19771 6 p.

    Research output: Contribution to journalArticle

  2. Variation in the interaction between alleles of HvAPETALA2 and microRNA172 determines the density of grains on the barley inflorescence

    Houston, K., McKim, S. M., Comadran, J., Bonar, N., Druka, I., Uzrek, N., Cirillo, E., Guzy-Wrobelska, J., Collins, N. C., Halpin, C., Hansson, M., Dockter, C., Druka, A. & Waugh, R. 8 Oct 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 41, p. 16675-16680 6 p.

    Research output: Contribution to journalArticle

  3. Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains

    Emmerich, C. H., Ordureau, A., Strickson, S., Arthur, J. S. C., Pedrioli, P. G. A., Komander, D. & Cohen, P. 17 Sep 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 38, p. 15247-15252 6 p.

    Research output: Contribution to journalArticle

  4. Live cell imaging shows reversible assembly of the TatA component of the twin-arginine protein transport system

    Alcock, F., Baker, M. A. B., Greene, N. P., Palmer, T., Wallace, M. I. & Berks, B. C. 17 Sep 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 38, p. E3650-E3659 10 p.

    Research output: Contribution to journalArticle

  5. BslA is a self-assembling bacterial hydrophobin that coats the Bacillus subtilis biofilm

    Hobley, L., Ostrowski, A., Rao, F. V., Bromley, K. M., Porter, M., Prescott, A. R., Macphee, C. E., van Aalten, D. M. F. & Stanley-Wall, N. R. 13 Aug 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 33, p. 13600-13605 6 p.

    Research output: Contribution to journalArticle

  6. Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery

    Silvestre, H. L., Blundell, T. L., Abell, C. & Ciulli, A. 6 Aug 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 32, p. 12984-12989 6 p.

    Research output: Contribution to journalArticle

  7. TRNA tKUUU, tQUUG, and tEUUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding

    Rezgui, V. A. N., Tyagi, K., Ranjan, N., Konevega, A. L., Mittelstaet, J., Rodnina, M. V., Peter, M. & Pedrioli, P. G. A. 23 Jul 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 30, p. 12289-12294 6 p.

    Research output: Contribution to journalArticle

  8. Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation

    Kawasaki, N., Vela, J. L., Nycholat, C. M., Rademacher, C., Khurana, A., van Rooijen, N., Crocker, P. R., Kronenberg, M. & Paulson, J. C. 7 May 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 19, p. 7826-7831 6 p.

    Research output: Contribution to journalArticle

  9. Evolution of modular intraflagellar transport from a coatomer-like progenitor

    van Dam, T. J. P., Townsend, M. J., Turk, M., Schlessinger, A., Sali, A., Field, M. C. & Huynen, M. A. 23 Apr 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 17, p. 6943-6948 6 p.

    Research output: Contribution to journalArticle

  10. Mechanical model of blebbing in nuclear lamin meshworks

    Funkhouser, C. M., Sknepnek, R., Shimi, T., Goldman, A. E., Goldman, R. D. & de la Cruz, M. O. 26 Feb 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 9, p. 3248-3253 6 p.

    Research output: Contribution to journalArticle

  11. Chronic exposure to arsenic in drinking water can lead to resistance to antimonial drugs in a mouse model of visceral leishmaniasis

    Perry, M. R., Wyllie, S., Raab, A., Feldmann, J. & Fairlamb, A. H. 2013 In : Proceedings of the National Academy of Sciences. n/a, n/a

    Research output: Contribution to journalArticle

  12. Crystal structure and functional mechanism of a human antimicrobial membrane channel

    Song, C., Weichbrodt, C., Salnikov, E. S., Dynowski, M., Forsberg, B. O., Bechinger, B., Steinem, C., De Groot, B. L., Zachariae, U. & Zeth, K. 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 12, p. 4586-4591 6 p.

    Research output: Contribution to journalArticle

  13. Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival

    Song, J., Lokmic, Z., Lämmermann, T., Rolf, J., Wu, C., Zhang, X., Hallmann, R., Hannocks, M-J., Horn, N., Ruegg, M. A., Sonnenberg, A., Georges-Labouesse, E., Winkler, T. H., Kearney, J. F., Cardell, S. & Sorokin, L. 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 31, p. E2915-E2924 10 p.

    Research output: Contribution to journalArticle

  14. Structural basis for cooperativity of CRM1 export complex formation

    Monecke, T., Haselbach, D., Voß, B., Russek, A., Neumann, P., Thomson, E., Hurt, E., Zachariae, U., Stark, H., Grubmul̈ler, H., Dickmanns, A. & Ficner, R. 2013 In : Proceedings of the National Academy of Sciences of the United States of America. 110, 3, p. 960-965 6 p.

    Research output: Contribution to journalArticle

  15. P38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

    Risco, A., Del Dresno, C., Mambol, A., Alsina-Beauchamp, D., MacKenzie, K. F., Yang, H-T., Barber, D. F., Morcelle, C., Arthur, J. S. C., Ley, S. C., Ardavin, C. F. & Cuenda, A. 10 Jul 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 28, p. 11200-11205 6 p.

    Research output: Contribution to journalArticle

  16. Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes

    Baker, N., Glover, L., Munday, J. C., Andres, D. A., Barrett, M. P., de Koning, H. P. & Horn, D. 3 Jul 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 27, p. 10996-11001 6 p.

    Research output: Contribution to journalArticle

  17. Extending the timescale and range of ecosystem services through paleoenvironmental analyses, exemplified in the lower Yangtze basin

    Dearing, J. A., Yang, X., Dong, X., Zhang, E., Chen, X., Langdon, P. G., Zhang, K., Zhang, W. & Dawson, T. P. 1 May 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 18, p. E1111-E1120 10 p.

    Research output: Contribution to journalArticle

  18. Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death

    Gammoh, N., Lam, D., Puente, C., Marks, P. A., Jiang, X. & Ganley, I. 24 Apr 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 17, p. 6561-6565 5 p.

    Research output: Contribution to journalArticle

  19. Electroconvulsive therapy reduces frontal cortical connectivity in severe depressive disorder

    Perrin, J. S., Merz, S., Bennett, D. M., Currie, J., Steele, D. J., Reid, I. C. & Schwarzbauer, C. 3 Apr 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 14, p. 5464-5468 5 p.

    Research output: Contribution to journalArticle

  20. Host-targeting protein 1 (SpHtp1) from the oomycete Saprolegnia parasitica translocates specifically into fish cells in a tyrosine-O-sulphate-dependent manner

    Wawra, S., Bain, J., Durward, E., de Bruijn, I., Minor, K. L., Matena, A., Loebach, L., Whisson, S. C., Bayer, P., Porter, A. J., Birch, P. R. J., Secombes, C. J. & van West, P. 7 Feb 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 6, p. 2096-2101 6 p.

    Research output: Contribution to journalArticle

  21. Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process

    Castaneda-Bueno, M., Graciela Cervantes-Perez, L., Vazquez, N., Uribe, N., Kantesaria, S., Morla, L., Bobadilla, N. A., Doucet, A., Alessi, D. R. & Gamba, G. 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 20, p. 7929-7934 6 p.

    Research output: Contribution to journalArticle

  22. Leishmania TDR1 structure, a unique trimeric glutathione transferase capable of deglutathionylation and antimonial prodrug activation

    Fyfe, P. K., Westrop, G. D., Silva, A. M., Coombs, G. H. & Hunter, W. N. 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 29, p. 11693-11698 6 p.

    Research output: Contribution to journalArticle

  23. Live imaging of nascent RNA dynamics reveals distinct types of transcriptional pulse regulation

    Muramoto, T., Cannon, D., Gierlinski, M., Corrigan, A., Barton, G. J. & Chubb, J. R. 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 19, p. 7350-7355 6 p.

    Research output: Contribution to journalArticle

  24. Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages

    Clark, K., Mackenzie, K. F., Petkevicius, K., Kristariyanto, Y., Zhang, J., Choi, H. G., Peggie, M., Plater, L., Pedrioli, P. G. A., McIver, E., Gray, N. S., Arthur, J. S. C. & Cohen, P. 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 42, p. 16986-91 6 p.

    Research output: Contribution to journalArticle

  25. Tibet is one of the centers of domestication of cultivated barley

    Dai, F., Nevo, E., Wu, D., Comadran, J., Zhou, M., Qiu, L., Chen, Z., Beiles, A., Chen, G. & Zhang, G. 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 42, p. 16969-16973 5 p.

    Research output: Contribution to journalArticle

  26. Pannexins in ischemia-induced neurodegeneration

    Bargiotas, P., Krenz, A., Hormuzdi, S. G., Ridder, D. A., Herb, A., Barakat, W., Penuela, S., von Engelhardt, J., Monyer, H. & Schwaninger, M. 20 Dec 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 51, p. 20772-20777 6 p.

    Research output: Contribution to journalArticle

  27. Phytophthora infestans effector AVRblb2 prevents secretion of a plant immune protease at the haustorial interface

    Bozkurt, T. O., Schornack, S., Win, J., Shindo, T., Ilyas, M., Oliva, R., Cano, L. M., Jones, A. M. E., Huitema, E., van der Hoorn, R. A. L. & Kamoun, S. 20 Dec 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 51, p. 20832-20837 6 p.

    Research output: Contribution to journalArticle

  28. Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability

    Ikematsu, N., Dallas, M. L., Ross, F. A., Lewis, R. W., Rafferty, J. N., David, J. A., Suman, R., Peers, C., Hardie, D. G. & Evans, A. M. 1 Nov 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 44, p. 18132-18137 6 p.

    Research output: Contribution to journalArticle

  29. Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

    Leigh, I. M. & 32 others Wang, N. J., Sanborn, Z., Arnett, K. L., Bayston, L. J., Liao, W., Proby, C. M., Collisson, E. A., Gordon, P. B., Jakkula, L., Pennypacker, S., Zou, Y., Sharma, M., North, J. P., Vemula, S. S., Mauro, T. M., Neuhaus, I. M., LeBoit, P. E., Hur, J. S., Park, K., Huh, N., Kwok, P-Y., Arron, S. T., Massion, P. P., Bale, A. E., Haussler, D., Cleaver, J. E., Gray, J. W., Spellman, P. T., South, A. P., Aster, J. C., Blacklow, S. C. & Cho, R. J. 25 Oct 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 43, p. 17761-17766 6 p.

    Research output: Contribution to journalArticle

  30. The TRAF-associated protein TANK facilitates cross-talk within the I kappa B kinase family during Toll-like receptor signaling

    Clark, K., Takeuchi, O., Akira, S. & Cohen, P. 11 Oct 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 41, p. 17093-17098 6 p.

    Research output: Contribution to journalArticle

  31. Genetic analysis of specific and redundant roles for p38 alpha and p38 beta MAPKs during mouse development

    del Barco Barrantes, I., Manuel Coya, J., Maina, F., Arthur, J. S. C. & Nebreda, A. R. 2 Aug 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 31, p. 12764-12769 6 p.

    Research output: Contribution to journalArticle

  32. Control of mTORC1 signaling by the Opitz syndrome protein MID1

    Liu, E., Knutzen, C. A., Krauss, S., Schweiger, S. & Chiang, G. G. 24 May 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 21, p. 8680-8685 6 p.

    Research output: Contribution to journalArticle

  33. Platonic and Archimedean geometries in multicomponent elastic membranes

    Vernizzi, G., Sknepnek, R. & de la Cruz, M. O. 15 Mar 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 11, p. 4292-4296 5 p.

    Research output: Contribution to journalArticle

  34. Temperature-sensitive ipl1-2/Aurora B mutation is suppressed by mutations in TOR complex 1 via the Glc7/PP1 phosphatase

    Tatchell, K., Makrantoni, V., Stark, M. J. R. & Robinson, L. C. 8 Mar 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 10, p. 3994-3999 6 p.

    Research output: Contribution to journalArticle

  35. Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains

    Akutsu, M., Ye, Y., Virdee, S., Chin, J. W. & Komander, D. 8 Feb 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 6, p. 2228-2233 6 p.

    Research output: Contribution to journalArticle

  36. Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning

    Bell, K. F., Al-Mubarak, B., Fowler, J. H., Baxter, P. S., Gupta, K., Tsujita, T., Chowdhry, S., Patani, R., Chandran, S., Horsburgh, K., Hayes, J. D. & Hardingham, G. E. 4 Jan 2011 In : Proceedings of the National Academy of Sciences of the United States of America. 108, 1, p. E1-E2 2 p.

    Research output: Contribution to journalLetter

  37. Functional dynamics in the voltage-dependent anion channel

    Villinger, S., Briones, R., Giller, K., Zachariae, U., Lange, A., De Groot, B. L., Griesinger, C., Becker, S. & Zweckstetter, M. 28 Dec 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 52, p. 22546-22551 6 p.

    Research output: Contribution to journalArticle

  38. Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling

    Kickstein, E., Krauss, S., Thornhill, P., Rutschow, D., Zeller, R., Sharkey, J., Williamson, R., Fuchs, M., Koehler, A., Glossmann, H., Schneider, R., Sutherland, C. & Schweiger, S. 14 Dec 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 50, p. 21830-21835 6 p.

    Research output: Contribution to journalArticle

  39. Uncoupling the Warburg effect from cancer

    Najafov, A. & Alessi, D. R. 9 Nov 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 45, p. 19135-19136 2 p.

    Research output: Contribution to journalComment/debate

  40. Ancient class of translocated oomycete effectors targets the host nucleus

    Schornack, S., van Damme, M., Bozkurt, T. O., Cano, L. M., Smoker, M., Thines, M., Gaulin, E., Kamoun, S. & Huitema, E. 5 Oct 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 40, p. 17421-17426 6 p.

    Research output: Contribution to journalArticle

  41. Advanced hardware and software tools for fast multidimensional imaging of living cells

    Swedlow, J. R. 14 Sep 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 37, p. 16005-16006 2 p.

    Research output: Contribution to journalEditorial

  42. The serine/arginine-rich protein SF2/ASF regulates protein sumoylation

    Pelisch, F., Gerez, J., Druker, J., Schor, I. E., Munoz, M. J., Risso, G., Petrillo, E., Westman, B. J., Lamond, A. I., Arzt, E. & Srebrow, A. 14 Sep 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 37, p. 16119-16124 6 p.

    Research output: Contribution to journalArticle

  43. DNA polymerase theta up-regulation is associated with poor survival in breast cancer, perturbs DNA replication, and promotes genetic instability

    Thompson, A. & 23 others Lemee, F., Bergoglio, V., Fernandez-Vidal, A., Machado-Silva, A., Pillaire, M-J., Bieth, A., Gentil, C., Baker, L., Martin, A-L., Leduc, C., Lam, E., Magdeleine, E., Filleron, T., Oumouhou, N., Kaina, B., Seki, M., Grimal, F., Lacroix-Triki, M., Roche, H., Bourdon, J-C., Wood, R. D., Hoffmann, J-S. & Cazaux, C. 27 Jul 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 30, p. 13390-13395 6 p.

    Research output: Contribution to journalArticle

  44. Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme

    Wilson, T. J., Li, N-S., Lu, J., Frederiksen, J. K., Piccirilli, J. A. & Lilley, D. M. J. 29 Jun 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 26, p. 11751-11756 6 p.

    Research output: Contribution to journalArticle

  45. Activity of any class IA PI3K isoform can sustain cell proliferation and survival

    Foukas, L. C., Berenjeno, I. M., Gray, A., Khwaja, A. & Vanhaesebroeck, B. 22 Jun 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 25, p. 11381-11386 6 p.

    Research output: Contribution to journalArticle

  46. Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase

    Mankouri, J., Tedbury, P. R., Gretton, S., Hughes, M. E., Griffin, S. D. C., Dallas, M. L., Green, K. A., Hardie, D. G., Peers, C. & Harris, M. 22 Jun 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 25, p. 11549-11554 6 p.

    Research output: Contribution to journalArticle

  47. Electrophilic tuning of the chemoprotective natural product sulforaphane

    Ahn, Y-H., Hwang, Y., Liu, H., Wang, X-J., Zhang, Y., Stephenson, K. K., Boronina, T. N., Cole, R. N., Dinkova-Kostova, A. T., Talalay, P. & Cole, P. A. 25 May 2010 In : Proceedings of the National Academy of Sciences of the United States of America. 107, 21, p. 9590-9595 6 p.

    Research output: Contribution to journalArticle

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