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Albena Dinkova-Kostova

  1. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

    Mills, E. L. , Ryan, D. G. , Prag, H. A. , Dikovskaya, D. , Menon, D. , Zaslona, Z. , Jedrychowski, M. P. , Costa, A. S. H. , Higgins, M. , Hams, E. , Szpyt, J. , Runtsch, M. C. , King, M. S. , McGouran, J. F. , Fischer, R. , Kessler, B. M. , McGettrick, A. F. , Hughes, M. M. , Carroll, R. G. , Booty, L. M. & 15 others Knatko, E. V., Meakin, P. J., Ashford, M. L. J., Modis, L. K., Brunori, G., Sévin, D. C., Fallon, P. G., Caldwell, S. T., Kunji, E. R. S., Chouchani, E. T., Frezza, C., Dinkova-Kostova, A. T., Hartley, R. C., Murphy, M. P. & O'Neill, L. A. 5 Apr 2018 In : Nature. 556, 7699, p. 113-117 5 p.

    Research output: Contribution to journalLetter

  2. Author Correction: Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates

    Bartolome, F., Esteras, N., Martin-Requero, A., Boutoleau-Bretonniere, C., Vercelletto, M., Gabelle, A., Ber, I. L., Honda, T., Dinkova-Kostova, A. T., Hardy, J., Carro, E. & Abramov, A. Y. 1 Mar 2018 In : Scientific Reports. 8, p. 1-2 2 p., 4064

    Research output: Contribution to journalArticle

  3. Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)

    Sharma, R. S., Harrison, D. J., Kisielewski, D., Cassidy, D. M., McNeilly, A. D., Gallagher, J. R., Walsh, S. V., Honda, T., McCrimmon, R. J., Dinkova-Kostova, A. T., Ashford, M. L. J., Dillon, J. F. & Hayes, J. D. 1 Mar 2018 In : CMGH: Cellular and Molecular Gastroenterology and Hepatology. 5, 3, p. 367-398 32 p.

    Research output: Contribution to journalArticle

  4. The role of Nrf2 signaling in counteracting neurodegenerative diseases

    Dinkova-Kostova, A. T., Kostov, R. V. & Kazantsev, A. G. 11 Jan 2018 In : FEBS Journal.

    Research output: Contribution to journalReview article

  5. Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

    Kalin, J. H. , Wu, . M. , Gomez, A. V. , Song, Y. , Das, . J. , Hayward, D. , Adejola, . N. , Wu, M. , Panova, I. , Chung, H. J. , Kim, E. , Roberts, H. J. , Roberts, J. M. , Prusevich, P. , Jeliazkov, J. R. , Burman, S. S. R. , Fairall, L. , Milano, C. , Eroglu, A. , Proby, C. & 14 others Dinkova-Kostova, A., Hancock, W. W., Gray, J. J., Bradner, J. E., Valente, S., Mai, A., Anders, N. M., Rudek, M. A., Hu, Y., Ryu, B., Schwabe, J. W. R., Mattevi, A., Alani, R. M. & Cole, P. A. 4 Jan 2018 In : Nature Communications. 9, 1, p. 1-13 13 p., 53

    Research output: Contribution to journalArticle

  6. Crosstalk between NRF2 and HIPK2 shapes cytoprotective responses

    Torrente, L., Sanchez, C., Moreno Dorta, R., Chowdhry, S., Cabello, P., Isono, K., Koseki, H., Honda, T., Hayes, J., Dinkova-Kostova, A. & de la Vega, L. 2 Nov 2017 In : Oncogene. 36, 44, p. 6204-6212 9 p.

    Research output: Contribution to journalArticle

  7. KEAP1 and done? Targeting the NRF2 pathway with sulforaphane: Targeting the NRF2 Pathway with Sulforaphane

    Dinkova-Kostova, A. T., Fahey, J. W., Kostov, R. V. & Kensler, T. W. Nov 2017 In : Trends in Food Science and Technology. 69, B, p. 257-269 13 p.

    Research output: Contribution to journalReview article

  8. Oxidative stress and chronic inflammation in osteoarthritis: can Nrf2 counteract these partners in crime?

    Marchev, A. S., Dimitrova, P. A., Burns, A. J., Kostov, R., Dinkova-Kostova, A. & Georgiev, M. I. 11 Sep 2017 In : Annals of the New York Academy of Sciences. 1401, p. 114-135 22 p.

    Research output: Contribution to journalReview article

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