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Albena T. Dinkova-Kostova

  1. A dicyanotriterpenoid induces cytoprotective enzymes and reduces multiplicity of skin tumors in UV-irradiated mice

    Dinkova-Kostova, A. T., Jenkins, S. N., Wehage, S. L., Huso, D. L., Benedict, A. L., Stephenson, K. K., Fahey, J. W., Liu, H., Liby, K. T., Honda, T., Gribble, G. W., Sporn, M. B. & Talalay, P. 21 Mar 2008 In : Biochemical and Biophysical Research Communications. 367, 4, p. 859-865 7 p.

    Research output: Contribution to journalArticle

  2. A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin

    Liby, K., Yore, M. M., Roebuck, B. D., Baumgartner, K. J., Honda, T., Sundararajan, C., Yoshizawa, H., Gribble, G. W., Williams, C. R., Risingsong, R., Royce, D. B., Dinkova-Kostova, A. T., Stephenson, K. K., Egner, P. A., Yates, M. S., Groopman, J. D., Kensler, T. W. & Sporn, M. B. 15 Aug 2008 In : Cancer Research. 68, 16, p. 6727-6733 7 p.

    Research output: Contribution to journalArticle

  3. Activation of the NRF2 Signaling Pathway by Copper-Mediated Redox Cycling of Para- and Ortho-Hydroquinones

    Wang, X. J., Hayes, J. D., Higgins, L. G., Wolf, C. R. & Dinkova-Kostova, A. T. 29 Jan 2010 In : Chemistry & Biology. 17, 1, p. 75-85 11 p.

    Research output: Contribution to journalArticle

  4. An Exceptionally Potent Inducer of Cytoprotective Enzymes elucidation of the structural features that determine inducer potency and reactivity with Keap1

    Dinkova-Kostova, A. T., Talalay, P., Sharkey, J., Zhang, Y., Holtzclaw, W. D., Wang, X. J., David, E., Schiavoni, K. H., Finlayson, S., Mierke, D. F. & Honda, T. 29 Oct 2010 In : Journal of Biological Chemistry. 285, 44, p. 33747-33755 9 p.

    Research output: Contribution to journalArticle

  5. Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway

    Hayes, J. D., McMahon, M., Chowdhry, S. & Dinkova-Kostova, A. T. 2010 In : Antioxidants & Redox Signaling. 13, 11, p. 1713-1748 36 p.

    Research output: Contribution to journalArticle

  6. Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity

    Calabrese, V., Cornelius, C., Mancuso, C., Pennisi, G., Calafato, S., Bellia, F., Bates, T. E., Giuffrida Stella, A. M., Schapira, T., Rizzarelli, E. & Dinkova-Kostova, A. 2008 In : Neurochemical Research. 33, 12, p. 2444-71 28 p.

    Research output: Contribution to journalArticle

  7. Chemical constituents and NAD(P)H:Quinone oxidoreductase 1 (NQO1) inducer activity of Teucrium oliverianum Ging. ex Benth

    Shahat, A. A., Alsaid, M. S., Khan, J. A., Higgins, M. & Dinkova-Kostova, A. T. Apr 2016 In : Indian Journal of Traditional Knowledge. 15, 2, p. 232-236 5 p.

    Research output: Contribution to journalArticle

  8. Chemical tuning enhances both potency toward Nrf2 and in vitro therapeutic index of triterpenoids

    Copple, I. M., Shelton, L. M., Walsh, J., Kratschmar, D. V., Lister, A., Odermatt, A., Goldring, C. E., Dinkova-Kostova, A. T., Honda, T. & Park, B. K. Aug 2014 In : Toxicological Sciences. 140, 2, p. 462-469 8 p.

    Research output: Contribution to journalArticle

  9. Design, synthesis, and evaluation of triazole derivatives that induce Nrf2 dependent gene products and inhibit the Keap1-Nrf2 protein-protein interaction

    Bertrand, H. C., Schaap, M., Baird, L., Georgakopoulos, N. D., Fowkes, A., Thiollier, C., Kachi, H., Dinkova-Kostova, A. T. & Wells, G. 24 Sep 2015 In : Journal of Medicinal Chemistry. 58, 18, p. 7186-7194 9 p.

    Research output: Contribution to journalArticle

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