Discovery - University of Dundee - Online Publications

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Albena Dinkova-Kostova

  1. Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates

    Bartolome, F., Esteras, N., Martin-Requero, A., Boutoleau-Bretonniere, C., Vercelletto, M., Gabelle, A., Le Ber, I., Honda, T., Dinkova-Kostova, A. T., Hardy, J., Carro, E. & Abramov, A. Y. 10 May 2017 In : Scientific Reports. 7, p. 1-14 14 p., 1666

    Research output: Contribution to journalArticle

  2. Activation of Nrf2 signaling augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity

    Olagnier, D., Lababidi, R. R., Bel Hadj, S., Sze, A., Liu, Y., Dayalan Naidu, S., Ferrari, M., Jiang, Y., Chiang, C., Beljanski, V., Goulet, M-L., Knatko, E. V., Dinkova-Kostova, A. T., Hiscott, J. & Lin, R. 27 Apr 2017 In : Molecular Therapy. 17 p.

    Research output: Contribution to journalArticle

  3. Flavonolignan 2,3-dehydrosilydianin activates Nrf2 and upregulates NAD(P)H: quinone oxidoreductase 1 in Hepa1c1c7 cells

    Roubalová, L., Dinkova-Kostova, A. T., Biedermann, D., Křen, V., Ulrichová, J. & Vrba, J. 24 Apr 2017 In : Fitoterapia. 119, p. 115-120 6 p.

    Research output: Contribution to journalArticle

  4. Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants

    Dinkova-Kostova, A. T., Kostov, R. V. & Canning, P. 1 Mar 2017 In : Archives of Biochemistry and Biophysics. 617, p. 84-93 10 p.

    Research output: Contribution to journalArticle

  5. KEAP1 and done? Targeting the NRF2 pathway with sulforaphane

    Dinkova-Kostova, A. T., Fahey, J. W., Kostov, R. V. & Kensler, T. W. 16 Feb 2017 In : Trends in Food Science and Technology. 13 p.

    Research output: Contribution to journalReview article

  6. NRF2 as an emerging therapeutic target

    Copple, I. M., Dinkova-Kostova, A. T., Kensler, T. W., Liby, K. T. & Wigley, W. C. 31 Jan 2017 In : Oxidative Medicine and Cellular Longevity. 2017, 2 p., 8165458

    Research output: Contribution to journalEditorial

  7. Regulation of the mammalian heat shock factor 1

    Dayalan Naidu, S. & Dinkova-Kostova, A. 4 Jan 2017 In : FEBS Journal.

    Research output: Contribution to journalReview article

  8. Whole-exome sequencing validates a preclinical mouse model for the prevention and treatment of cutaneous squamous cell carcinoma

    Knatko, E. V., Praslicka, B., Higgins, M., Evans, A., Purdie, K. J., Harwood, C. A., Proby, C. M., Ooi, A. & Dinkova-Kostova, A. T. Jan 2017 In : Cancer Prevention Research. 10, 1, p. 67-75 9 p.

    Research output: Contribution to journalArticle

  9. Semisynthetic flavonoid 7-O-galloylquercetin activates Nrf2 and induces Nrf2-dependent gene expression in RAW264.7 and Hepa1c1c7 cells

    Roubalová, L., Biedermann, D., Papoušková, B., Vacek, J., Kuzma, M., Křen, V., Ulrichová, J., Dinkova-Kostova, A. T. & Vrba, J. 25 Dec 2016 In : Chemico-Biological Interactions. 260, p. 58-66 9 p.

    Research output: Contribution to journalArticle

  10. Regulation of the CNC-bZIP transcription factor Nrf2 by Keap1 and the axis between GSK-3 and β-TrCP

    Hayes, J. D., Ebisine, K., Sharma, R. S., Chowdhry, S., Dinkova-Kostova, A. T. & Sutherland, C. Dec 2016 In : Current Opinion in Toxicology. 1, p. 92-103 12 p.

    Research output: Contribution to journalReview article

  11. The multifaceted role of Nrf2 in mitochondrial function

    Holmström, K. M., Kostov, R. V. & Dinkova-Kostova, A. T. Dec 2016 In : Current Opinion in Toxicology. 1, p. 80-91 12 p.

    Research output: Contribution to journalReview article

  12. Nrf2-mediated neuroprotection response to recurrent hypoglycemia is insufficient to prevent cognitive impairment in a rodent model of type 1 diabetes

    McNeilly, A. D., Gallagher, J. R., Dinkova-Kostova, A. T., Hayes, J. D., Sharkey, J., Ashford, M. L. J. & McCrimmon, R. J. 1 Oct 2016 In : Diabetes. 65, 10, p. 3151-3160 10 p.

    Research output: Contribution to journalArticle

  13. Heat Shock Factor 1 is a Substrate for p38 Mitogen-Activated Protein Kinases

    Dayalan Naidu, S., Sutherland, C., Zhang, Y., Risco, A., de la Vega, L., Caunt, C. J., Hastie, C. J., Lamont, D. J., Torrente, L., Chowdhry, S., Benjamin, I. J., Keyse, S. M., Cuenda, A. & Dinkova-Kostova, A. T. 15 Sep 2016 In : Molecular and Cellular Biology. 36, 18, p. 2403-2417 15 p.

    Research output: Contribution to journalArticle

  14. Electron affinity of tricyclic, bicyclic, and monocyclic compounds containing cyanoenones correlates with their potency as inducers of a cytoprotective enzyme

    Bensasson, R. V., Dinkova-Kostova, A. T., Zheng, S., Saito, A., Li, W., Zoete, V. & Honda, T. 1 Sep 2016 In : Bioorganic & Medicinal Chemistry Letters. 26, 17, p. 4345-4349 5 p.

    Research output: Contribution to journalArticle

  15. NAD(P)H: quinone oxidoreductase 1 inducer activity of some novel anilinoquinazoline derivatives

    Ghorab, M. M., Alsaid, M. S., Higgins, M., Dinkova-Kostova, A. T., Shahat, A. A., Elghazawy, N. H. & Arafa, R. K. 8 Aug 2016 In : Drug Design, Development and Therapy. 10, p. 2515-2524 10 p.

    Research output: Contribution to journalArticle

  16. Rhodiola rosea L.: from golden root to green cell factories

    Marchev, A. S., Dinkova-Kostova, A. T., György, Z., Mirmazloum, I., Aneva, I. Y. & Georgiev, M. I. Aug 2016 In : Phytochemistry Reviews. 15, 4, p. 515-536 22 p.

    Research output: Contribution to journalArticle

  17. SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models

    Dinkova-Kostova, A. T. & 23 others Quinti, L., Casale, M., Moniot, S., Pais, T. F., Van Kanegan, M. J., Kaltenbach, L. S., Pallos, J., Lim, R. G., Naidu, S. D., Runne, H., Meisel, L., Rauf, N. A., Leyfer, D., Maxwell, M. M., Saiah, E., Landers, J. E., Luthi-Carter, R., Abagyan, R., Steegborn, C., Marsh, J. L., Lo, D. C., Thompson, L. M. & Kazantsev, A. G. 21 Jul 2016 In : Cell Chemical Biology. 23, 7, p. 849-861 13 p.

    Research output: Contribution to journalArticle

  18. Potency of extracts from selected Egyptian plants as inducers of the Nrf2-dependent chemopreventive enzyme NQO1

    Hamed, A. R., Hegazy, M-E. F., Higgins, M., Mohamed, T. A., Abdel-Azim, N. S., Pare, P. W. & Dinkova-Kostova, A. T. Jul 2016 In : Journal of Natural Medicines. 70, 3, p. 683-688 6 p.

    Research output: Contribution to journalArticle

  19. Loss of Nrf2 abrogates the protective effect of Keap1 down regulation in a preclinical model of cutaneous squamous cell carcinoma

    Knatko, E. V., Higgins, M., Fahey, J. W. & Dinkova-Kostova, A. 24 May 2016 In : Scientific Reports. 6, 7 p., 25804

    Research output: Contribution to journalArticle

  20. Nrf2 activation in the treatment of neurodegenerative diseases: A focus on its role in mitochondrial bioenergetics and function

    Esteras, N., Dinkova-Kostova, A. T. & Abramov, A. Y. May 2016 In : Biological Chemistry. 397, 5, p. 383-400 18 p.

    Research output: Contribution to journalArticle

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