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Albena Dinkova-Kostova

  1. KEAP1 and done? Targeting the NRF2 pathway with sulforaphane

    Dinkova-Kostova, A. T., Fahey, J. W., Kostov, R. V. & Kensler, T. W. Nov 2017 In : Trends in Food Science and Technology. 69, B, p. 257-269 13 p.

    Research output: Contribution to journalReview article

  2. Metabolic and Homeostatic Changes in Seizures and Acquired Epilepsy-Mitochondria, Calcium Dynamics and Reactive Oxygen Species

    Kovac, S., Dinkova Kostova, A. T., Herrmann, A. M., Melzer, N., Meuth, S. G. & Gorji, A. 8 Sep 2017 In : International Journal of Molecular Sciences. 18, 9, p. 1-19 19 p., 1935

    Research output: Contribution to journalReview article

  3. Transcription factors NRF2 and HSF1 have opposing functions in autophagy

    Dayalan Naidu, S., Dikovskaya, D., Gaurilcikaite, E., Knatko, E., Healy, Z. R., Mohan, H., Koh, . G., Laurell, A., Ball, G., Olagnier, D., de la Vega, L., Ganley, I., Talalay, P. & Dinkova-Kostova, A. 8 Sep 2017 In : Scientific Reports. 7, p. 1-12 12 p., 11023

    Research output: Contribution to journalArticle

  4. Crosstalk between NRF2 and HIPK2 shapes cytoprotective responses

    Torrente, L., Sanchez, C., Moreno Dorta, R., Chowdhry, S., Cabello, P., Isono, K., Koseki, H., Honda, T., Hayes, J., Dinkova-Kostova, A. & de la Vega, L. 10 Jul 2017 In : Oncogene.

    Research output: Contribution to journalArticle

  5. OxidaIve stress management in the hair follicle: Could targeting NRF2 counter age-related hair disorders and beyond?

    Jadkauskaite, L., Coulombe, P. A., Schäfer, M., Dinkova-Kostova, A. T., Paus, R. & Haslam, I. S. 7 Jul 2017 In : BioEssays. 9 p.

    Research output: Contribution to journalArticle

  6. Oxidative stress and chronic inflammation in osteoarthritis: can Nrf2 counteract these partners in crime?

    Marchev, A. S., Dimitrova, P. A., Burns, A. J., Kostov, R., Dinkova-Kostova, A. & Georgiev, M. I. 29 Jun 2017 In : Annals of the New York Academy of Sciences. 1401, p. 114-135 22 p.

    Research output: Contribution to journalReview article

  7. KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients

    Quinti, L. , Dayalan Naidu, S. , Träge, U. , Chen, X. , Kegel-Gleason, K. , Lleres, D. , Connolly, C. , Chopra, V. , Low, C. , Moniot, S. , Sapp, E. , Tousley, A. R. , Vodicka, P. , Van Kanegan, M. J. , Kaltenbach, L. S. , Crawford, L. A. , Fuszard, M. , Higgins, M. , Miller, J. R. C. , Farmer, R. E. & 19 others Potluri, V., Samajdar, S., Meisel, L., Zhang, N., Snyder, A., Stein, R., Hersch, S. M., Ellerby, L. M., Weerapana, E., Schwarzschild, M. A., Steegborn, C., Leavitt, B. R., Degterev, A., Tabrizi, S. J., Lo, D. C., DiFiglia, M., Thompson, L. M., Dinkova-Kostova, A. & Kazantsev, A. G. 6 Jun 2017 In : Proceedings of the National Academy of Sciences of the United States of America. 114, 23, p. e4676-e4685 10 p.

    Research output: Contribution to journalArticle

  8. Flavonolignan 2,3-dehydrosilydianin activates Nrf2 and upregulates NAD(P)H: quinone oxidoreductase 1 in Hepa1c1c7 cells

    Roubalová, L., Dinkova-Kostova, A. T., Biedermann, D., Křen, V., Ulrichová, J. & Vrba, J. Jun 2017 In : Fitoterapia. 119, p. 115-120 6 p.

    Research output: Contribution to journalArticle

  9. Regulation of the mammalian heat shock factor 1

    Dayalan Naidu, S. & Dinkova-Kostova, A. T. Jun 2017 In : FEBS Journal. 284, 11, p. 1606-1627 22 p.

    Research output: Contribution to journalReview article

  10. Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates

    Bartolome, F., Esteras, N., Martin-Requero, A., Boutoleau-Bretonniere, C., Vercelletto, M., Gabelle, A., Le Ber, I., Honda, T., Dinkova-Kostova, A. T., Hardy, J., Carro, E. & Abramov, A. Y. 10 May 2017 In : Scientific Reports. 7, p. 1-14 14 p., 1666

    Research output: Contribution to journalArticle

  11. Activation of Nrf2 signaling augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity

    Olagnier, D., Lababidi, R. R., Bel Hadj, S., Sze, A., Liu, Y., Dayalan Naidu, S., Ferrari, M., Jiang, Y., Chiang, C., Beljanski, V., Goulet, M-L., Knatko, E. V., Dinkova-Kostova, A. T., Hiscott, J. & Lin, R. 27 Apr 2017 In : Molecular Therapy. 17 p.

    Research output: Contribution to journalArticle

  12. Activation of Nrf2 signaling as a common treatment of neurodegenerative diseases

    Dinkova-Kostova, A. T. & Kazantsev, A. G. Apr 2017 In : Neurodegenerative Disease Management. 7, 2, p. 97-100 4 p.

    Research output: Contribution to journalEditorial

  13. Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants

    Dinkova-Kostova, A. T., Kostov, R. V. & Canning, P. 1 Mar 2017 In : Archives of Biochemistry and Biophysics. 617, p. 84-93 10 p.

    Research output: Contribution to journalArticle

  14. NRF2 as an emerging therapeutic target

    Copple, I. M., Dinkova-Kostova, A. T., Kensler, T. W., Liby, K. T. & Wigley, W. C. 31 Jan 2017 In : Oxidative Medicine and Cellular Longevity. 2017, 2 p., 8165458

    Research output: Contribution to journalEditorial

  15. Whole-exome sequencing validates a preclinical mouse model for the prevention and treatment of cutaneous squamous cell carcinoma

    Knatko, E. V., Praslicka, B., Higgins, M., Evans, A., Purdie, K. J., Harwood, C. A., Proby, C. M., Ooi, A. & Dinkova-Kostova, A. T. Jan 2017 In : Cancer Prevention Research. 10, 1, p. 67-75 9 p.

    Research output: Contribution to journalArticle

  16. Semisynthetic flavonoid 7-O-galloylquercetin activates Nrf2 and induces Nrf2-dependent gene expression in RAW264.7 and Hepa1c1c7 cells

    Roubalová, L., Biedermann, D., Papoušková, B., Vacek, J., Kuzma, M., Křen, V., Ulrichová, J., Dinkova-Kostova, A. T. & Vrba, J. 25 Dec 2016 In : Chemico-Biological Interactions. 260, p. 58-66 9 p.

    Research output: Contribution to journalArticle

  17. Regulation of the CNC-bZIP transcription factor Nrf2 by Keap1 and the axis between GSK-3 and β-TrCP

    Hayes, J. D., Ebisine, K., Sharma, R. S., Chowdhry, S., Dinkova-Kostova, A. T. & Sutherland, C. Dec 2016 In : Current Opinion in Toxicology. 1, p. 92-103 12 p.

    Research output: Contribution to journalReview article

  18. The multifaceted role of Nrf2 in mitochondrial function

    Holmström, K. M., Kostov, R. V. & Dinkova-Kostova, A. T. Dec 2016 In : Current Opinion in Toxicology. 1, p. 80-91 12 p.

    Research output: Contribution to journalReview article

  19. Nrf2-mediated neuroprotection response to recurrent hypoglycemia is insufficient to prevent cognitive impairment in a rodent model of type 1 diabetes

    McNeilly, A. D., Gallagher, J. R., Dinkova-Kostova, A. T., Hayes, J. D., Sharkey, J., Ashford, M. L. J. & McCrimmon, R. J. 1 Oct 2016 In : Diabetes. 65, 10, p. 3151-3160 10 p.

    Research output: Contribution to journalArticle

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