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Albena T. Dinkova-Kostova

  1. The multifaceted role of Nrf2 in mitochondrial function

    Holmström, K. M., Kostov, R. V. & Dinkova-Kostova, A. 1 Dec 2016 In : Current Opinion in Toxicology. 1, p. 80-91 12 p.

    Research output: Contribution to journalArticle

  2. Semisynthetic flavonoid 7-O-galloylquercetin activates Nrf2 and induces Nrf2-dependent gene expression in RAW264.7 and Hepa1c1c7 cells

    Roubalová, L., Biedermann, D., Papoušková, B., Vacek, J., Kuzma, M., Křen, V., Ulrichová, J., Dinkova-Kostova, A. T. & Vrba, J. 25 Dec 2016 In : Chemico-Biological Interactions. 260, p. 58-66 9 p.

    Research output: Contribution to journalArticle

  3. Nrf2-mediated neuroprotection response to recurrent hypoglycemia is insufficient to prevent cognitive impairment in a rodent model of type 1 diabetes

    McNeilly, A. D., Gallagher, J. R., Dinkova-Kostova, A. T., Hayes, J. D., Sharkey, J., Ashford, M. L. J. & McCrimmon, R. J. 1 Oct 2016 In : Diabetes. 65, 10, p. 3151-3160 10 p.

    Research output: Contribution to journalArticle

  4. Heat Shock Factor 1 is a Substrate for p38 Mitogen-Activated Protein Kinases

    Dayalan Naidu, S., Sutherland, C., Zhang, Y., Risco, A., de la Vega, L., Caunt, C. J., Hastie, C. J., Lamont, D. J., Torrente, L., Chowdhry, S., Benjamin, I. J., Keyse, S. M., Cuenda, A. & Dinkova-Kostova, A. T. 15 Sep 2016 In : Molecular and Cellular Biology. 36, 18, p. 2403-2417 15 p.

    Research output: Contribution to journalArticle

  5. Electron affinity of tricyclic, bicyclic, and monocyclic compounds containing cyanoenones correlates with their potency as inducers of a cytoprotective enzyme

    Bensasson, R. V., Dinkova-Kostova, A. T., Zheng, S., Saito, A., Li, W., Zoete, V. & Honda, T. 1 Sep 2016 In : Bioorganic & Medicinal Chemistry Letters. 26, 17, p. 4345-4349 5 p.

    Research output: Contribution to journalArticle

  6. NAD(P)H: quinone oxidoreductase 1 inducer activity of some novel anilinoquinazoline derivatives

    Ghorab, M. M., Alsaid, M. S., Higgins, M., Dinkova-Kostova, A. T., Shahat, A. A., Elghazawy, N. H. & Arafa, R. K. 8 Aug 2016 In : Drug Design, Development and Therapy. 10, p. 2515-2524 10 p.

    Research output: Contribution to journalArticle

  7. Keap1, the cysteine-based mammalian intracellular sensor for electrophiles and oxidants

    Dinkova-Kostova, A. T., Kostov, R. V. & Canning, P. 3 Aug 2016 In : Archives of Biochemistry and Biophysics. 10 p.

    Research output: Contribution to journalArticle

  8. Rhodiola rosea L.: from golden root to green cell factories

    Marchev, A. S., Dinkova-Kostova, A. T., György, Z., Mirmazloum, I., Aneva, I. Y. & Georgiev, M. I. Aug 2016 In : Phytochemistry Reviews. 15, 4, p. 515-536 22 p.

    Research output: Contribution to journalArticle

  9. SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models

    Dinkova-Kostova, A. T. & 23 others Quinti, L., Casale, M., Moniot, S., Pais, T. F., Van Kanegan, M. J., Kaltenbach, L. S., Pallos, J., Lim, R. G., Naidu, S. D., Runne, H., Meisel, L., Rauf, N. A., Leyfer, D., Maxwell, M. M., Saiah, E., Landers, J. E., Luthi-Carter, R., Abagyan, R., Steegborn, C., Marsh, J. L., Lo, D. C., Thompson, L. M. & Kazantsev, A. G. 21 Jul 2016 In : Cell Chemical Biology. 23, 7, p. 849-861 13 p.

    Research output: Contribution to journalArticle

  10. Potency of extracts from selected Egyptian plants as inducers of the Nrf2-dependent chemopreventive enzyme NQO1

    Hamed, A. R., Hegazy, M-E. F., Higgins, M., Mohamed, T. A., Abdel-Azim, N. S., Pare, P. W. & Dinkova-Kostova, A. T. Jul 2016 In : Journal of Natural Medicines. 70, 3, p. 683-688 6 p.

    Research output: Contribution to journalArticle

  11. Loss of Nrf2 abrogates the protective effect of Keap1 down regulation in a preclinical model of cutaneous squamous cell carcinoma

    Knatko, E. V., Higgins, M., Fahey, J. W. & Dinkova-Kostova, A. 24 May 2016 In : Scientific Reports. 6, 7 p., 25804

    Research output: Contribution to journalArticle

  12. Nrf2 activation in the treatment of neurodegenerative diseases: A focus on its role in mitochondrial bioenergetics and function

    Esteras, N., Dinkova-Kostova, A. T. & Abramov, A. Y. May 2016 In : Biological Chemistry. 397, 5, p. 383-400 18 p.

    Research output: Contribution to journalArticle

  13. Synthesis, molecular modeling and NAD(P)H: quinone oxidoreductase 1 inducer activity of novel 2-phenylquinazolin-4-amine derivatives

    Ghorab, M. M., Alsaid, M. S., Higgins, M., Dinkova-Kostova, A. T., Shahat, A. A., Elghazawy, N. H. & Arafa, R. K. 7 Apr 2016 In : Journal of Enzyme Inhibition and Medicinal Chemistry. p. 1-7 7 p.

    Research output: Contribution to journalArticle

  14. Chemical constituents and NAD(P)H:Quinone oxidoreductase 1 (NQO1) inducer activity of Teucrium oliverianum Ging. ex Benth

    Shahat, A. A., Alsaid, M. S., Khan, J. A., Higgins, M. & Dinkova-Kostova, A. T. Apr 2016 In : Indian Journal of Traditional Knowledge. 15, 2, p. 232-236 5 p.

    Research output: Contribution to journalArticle

  15. Filaggrin genotype does not determine the skin's threshold to UV-induced erythema

    Forbes, D., Johnston, L., Gardner, J., MacCallum, S. F., Campbell, L. E., Dinkova-Kostova, A. T., McLean, W. H. I., Ibbotson, S. H., Dawe, R. S. & Brown, S. J. Apr 2016 In : Journal of Allergy and Clinical Immunology. 137, 4, p. 1280-1282.e3 6 p.

    Research output: Contribution to journalLetter

  16. Bioactive polymethoxylated flavonoids from Chiliadenus montanus

    Hamed, A. R., Mohamed, T. A., Tawfik, W. A., Hassan, E. M., Higgins, M., El-Toumy, S. A. & Dinkova-Kostova, A. T. 31 Mar 2016 In : Journal of Chemical and Pharmaceutical Research. 8, 3, p. 788-793 6 p.

    Research output: Contribution to journalArticle

  17. NAD(P)H: Quinone oxidoreductase 1 inducer activity of novel 4-aminoquinazoline derivatives

    Ghorab, M. M., Alsaid, M. S., El-Gazzar, M. G., Higgins, M., Dinkova-Kostova, A. T. & Shahat, A. A. 21 Jan 2016 In : Journal of Enzyme Inhibition and Medicinal Chemistry. 7 p.

    Research output: Contribution to journalArticle

  18. Synthesis and NAD(P)H: Quinone oxidoreductase 1 inducer activity of acetamide and pyridine-3-carbonitrile derivatives

    Ghorab, M. M., Shahat, A. A., Alsaid, M. S., Higgins, M., Dinkova-Kostova, A. T. & Naser, A. A. 2016 In : Biomedical Research. 27, 4

    Research output: Contribution to journalArticle

  19. Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease

    Tebay, L. E., Robertson, H., Durant, S. T., Vitale, S. R., Penning, T. M., Dinkova-Kostova, A. T. & Hayes, J. D. Nov 2015 In : Free Radical Biology and Medicine. 88, Part B, p. 108-146 39 p.

    Research output: Contribution to journalArticle

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