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Blair H. Smith

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  1. Genome-wide association analysis identifies six new loci associated with forced vital capacity

    Smith, B. H. & 159 others Loth, D. W., Artigas, M. S., Gharib, S. A., Wain, L. V., Franceschini, N., Koch, B., Pottinger, T. D., Smith, A. V., Duan, Q., Oldmeadow, C., Lee, M. K., Strachan, D. P., James, A. L., Huffman, J. E., Vitart, V., Ramasamy, A., Wareham, N. J., Kaprio, J., Wang, X-Q., Trochet, H., Kähönen, M., Flexeder, C., Albrecht, E., Lopez, L. M., de Jong, K., Thyagarajan, B., Alves, A. C., Enroth, S., Omenaas, E., Joshi, P. K., Fall, T., Viñuela, A., Launer, L. J., Loehr, L. R., Fornage, M., Li, G., Wilk, J. B., Tang, W., Manichaikul, A., Lahousse, L., Harris, T. B., North, K. E., Rudnicka, A. R., Hui, J., Gu, X., Lumley, T., Wright, A. F., Hastie, N. D., Campbell, S., Kumar, R., Pin, I., Scott, R. A., Pietiläinen, K. H., Surakka, I., Liu, Y., Holliday, E. G., Schulz, H., Heinrich, J., Davies, G., Vonk, J. M., Wojczynski, M., Pouta, A., Johansson, A., Wild, S. H., Ingelsson, E., Rivadeneira, F., Völzke, H., Hysi, P. G., Eiriksdottir, G., Morrison, A. C., Rotter, J. I., Gao, W., Postma, D. S., White, W. B., Rich, S. S., Hofman, A., Aspelund, T., Couper, D., Smith, L. J., Psaty, B. M., Lohman, K., Burchard, E. G., Uitterlinden, A. G., Garcia, M., Joubert, B. R., McArdle, W. L., Musk, A. B., Hansel, N., Heckbert, S. R., Zgaga, L., van Meurs, J. B. J., Navarro, P., Rudan, I., Oh, Y-M., Redline, S., Jarvis, D. L., Zhao, J. H., Rantanen, T., O'Connor, G. T., Ripatti, S., Scott, R. J., Karrasch, S., Grallert, H., Gaddis, N. C., Starr, J. M., Wijmenga, C., Minster, R. L., Lederer, D. J., Pekkanen, J., Gyllensten, U., Campbell, H., Morris, A. P., Gläser, S., Hammond, C. J., Burkart, K. M., Beilby, J., Kritchevsky, S. B., Gudnason, V., Hancock, D. B., Williams, O. D., Polasek, O., Zemunik, T., Kolcic, I., Petrini, M. F., Wjst, M., Kim, W. J., Porteous, D. J., Generation Scotland, Viljanen, A., Heliövaara, M., Attia, J. R., Sayers, I., Hampel, R., Gieger, C., Deary, I. J., Boezen, H. M., Newman, A., Jarvelin, M-R., Wilson, J. F., Lind, L., Stricker, B. H., Teumer, A., Spector, T. D., Melén, E., Peters, M. J., Lange, L. A., Barr, R. G., Bracke, K. R., Verhamme, F. M., Sung, J., Hiemstra, P. S., Cassano, P. A., Sood, A., Hayward, C., Dupuis, J., Hall, I. P., Brusselle, G. G., Tobin, M. D. & London, S. J. Jul 2014 In : Nature Genetics. 46, 7, p. 669-677 9 p.

    Research output: Contribution to journalArticle

  2. Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study

    Norsworthy, P. J., Vandrovcova, J., Thomas, E. R. A., Campbell, A., Kerr, S. M., Biggs, J., Game, L., Soutar, A. K., Smith, B. H., Dominiczak, A. F., Porteous, D. J., Morris, A. D., Generation Scotland & Aitman, T. J. 23 Jun 2014 In : BMC Medical Genetics. 15, 7 p.70

    Research output: Contribution to journalArticle

  3. A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain

    Meng, W., Deshmukh, H. A., van Zuydam, N. R., Liu, Y., Donnelly, L. A., Zhou, K., Morris, A. D., Colhoun, H. M., Palmer, C. N. A., Smith, B. H., Wellcome Trust Case Control Consortium 2 (WTCCC2) & Surrogate Markers for Micro- and Macro-Vascular Hard Endpoints for Innovative Diabetes Tools (SUMMIT) Study Group 2014 In : European Journal of Pain.

    Research output: Contribution to journalArticle

  4. A study of National Health Service management of chronic osteoarthritis and low back pain

    Hart, O. R., Uden, R. M., McMullan, J. E., Ritchie, M. S., Williams, T. D. & Smith, B. H. 2014 In : Primary Health Care Research and Development. 10 p.

    Research output: Contribution to journalArticle

  5. Does a history of depression actually mediate smoking-related pain?: Findings from a cross-sectional general population-based study

    van Hecke, O., Torrance, N., Cochrane, L., Cavanagh, J., Donnan, P. T., Padmanabhan, S., Porteous, D. J., Hocking, L. & Smith, B. H. 2014 In : European Journal of Pain.

    Research output: Contribution to journalArticle

  6. Managing chronic pain in the non-specialist setting: a new SIGN guideline

    Smith, B. H., Hardman, J. D., Stein, A., Colvin, L. & SIGN Chronic Pain Guideline Development Group 2014 In : British Journal of General Practice. 64, 624, p. e462-e464 3 p.

    Research output: Contribution to journalArticle

  7. Molecular genetic contributions to socioeconomic status and intelligence

    Marioni, R. E., Davies, G., Hayward, C., Liewald, D., Kerr, S. M., Campbell, A., Luciano, M., Smith, B. H., Padmanabhan, S., Hocking, L. J., Hastie, N. D., Wright, A. F., Porteous, D. J., Visscher, P. M. & Deary, I. J. 2014 In : Intelligence. 44, May-June, p. 26-32 7 p.

    Research output: Contribution to journalArticle

  8. Cardiovascular risk factors associated with the metabolic syndrome are more prevalent in people reporting chronic pain: results from a cross-sectional general population study

    Goodson, N. J., Smith, B. H., Hocking, L. J., McGilchrist, M. M., Dominiczak, A. F., Morris, A., Porteous, D. J. & Goebel, A. Sep 2013 In : PAIN. 154, 9, p. 1595-1602 8 p.

    Research output: Contribution to journalArticle

  9. Association of DISC1 variants with age of onset in a population-based sample of recurrent major depression

    Thomson, P. A., MacIntyre, D. J., Hamilton, G., Dominiczak, A., Smith, B. H., Morris, A., Evans, K. L. & Porteous, D. J. Jul 2013 In : Molecular Psychiatry. 18, 7, p. 745-747 3 p.

    Research output: Contribution to journalLetter

  10. Cohort profile: Generation Scotland: Scottish Family Health Study (GS:SFHS). The study, its participants and their potential for genetic research on health and illness

    Smith, B. H., Campbell, A., Linksted, P., Fitzpatrick, B., Jackson, C., Kerr, S. M., Deary, I. J., Macintyre, D. J., Campbell, H., McGilchrist, M., Hocking, L. J., Wisely, L., Ford, I., Lindsay, R. S., Morton, R., Palmer, C. N. A., Dominiczak, A. F., Porteous, D. J. & Morris, A. D. Jun 2013 In : International Journal of Epidemiology. 42, 3, p. 689-700 12 p.

    Research output: Contribution to journalArticle

  11. Ask the experts: neuropathic pain from a primary care perspective

    Smith, B. H. May 2013 In : Pain Management. 3, 3, p. 173-6 4 p.

    Research output: Contribution to journalArticle

  12. Can pragmatic trials help us better understand chronic pain and improve treatment?

    Rowbotham, M. C., Gilron, I., Glazer, C., Rice, A. S. C., Smith, B. H., Stewart, W. F. & Wasan, A. D. May 2013 In : PAIN. 154, 5, p. 643-646 4 p.

    Research output: Contribution to journalArticle

  13. Neuropathic pain in the community: more under-treated than refractory?

    Torrance, N., Ferguson, J. A., Afolabi, E., Bennett, M. I., Serpell, M. G., Dunn, K. M. & Smith, B. H. May 2013 In : PAIN. 154, 5, p. 690–699 10 p.

    Research output: Contribution to journalArticle

  14. Cost-effectiveness of self-management methods for the treatment of chronic pain in an aging adult population: a systematic review of the literature

    Boyers, D., McNamee, P., Clarke, A., Jones, D., Martin, D., Schofield, P. & Smith, B. H. Apr 2013 In : Clinical Journal of Pain. 29, 4, p. 366-375 10 p.

    Research output: Contribution to journalArticle

  15. Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

    Smith, B. H. & 51 others Peters, M. J., Broer, L., Willemen, H. L. D. M., Eiriksdottir, G., Hocking, L. J., Holliday, K. L., Horan, M. A., Meulenbelt, I., Neogi, T., Popham, M., Schmidt, C. O., Soni, A., Valdes, A. M., Amin, N., Dennison, E. M., Eijkelkamp, N., Harris, T. B., Hart, D. J., Hofman, A., Huygen, F. J. P. M., Jameson, K. A., Jones, G. T., Launer, L. J., Kerkhof, H. J. M., De Kruijf, M., McBeth, J., Kloppenburg, M., Ollier, W. E., Oostra, B., Payton, A., Rivadeneira, F., Smith, A. V., Stolk, L., Teumer, A., Thomson, W., Uitterlinden, A. G., Wang, K., Van Wingerden, S. H., Arden, N. K., Cooper, C., Felson, D., Gudnason, V., Macfarlane, G. J., Pendleton, N., Slagboom, P. E., Spector, T. D., Völzke, H., Kavelaars, A., Van Duijn, C. M., Williams, F. M. K. & Van Meurs, J. B. J. Mar 2013 In : Annals of the Rheumatic Diseases. 72, 3, p. 427-436 10 p.

    Research output: Contribution to journalArticle

  16. Lessons from Mackenzie that still resonate

    Van Hecke, O., Smith, B. H. & Sullivan, F. M. Mar 2013 In : British Journal of General Practice. 63, 608, p. 158-159 2 p.

    Research output: Contribution to journalComment/debate

  17. Chronic pain epidemiology and its clinical relevance

    van Hecke, O., Torrance, N. & Smith, B. H. 2013 In : British Journal of Anaesthesia. 111, 1, p. 13-18 6 p.

    Research output: Contribution to journalArticle

  18. Neuropathic pain: a pathway for care developed by the British Pain Society

    Smith, B. H., Lee, J., Price, C. & Baranowski, A. P. 2013 In : British Journal of Anaesthesia. 111, 1, p. 73-79 7 p.

    Research output: Contribution to journalArticle

  19. Pedigree and genotyping quality analyses of over 10,000 DNA samples from the Generation Scotland: Scottish Family Health Study

    Kerr, S. M., Campbell, A., Murphy, L., Hayward, C., Jackson, C., Wain, L. V., Tobin, M. D., Dominiczak, A., Morris, A., Smith, B. H. & Porteous, D. J. 2013 In : BMC Medical Genetics. 14, 38

    Research output: Contribution to journalArticle

  20. Pharmacist-led management of chronic pain in primary care: results from a randomised controlled exploratory trial

    Bruhn, H., Bond, C. M., Elliott, A. M., Hannaford, P. C., Lee, A. J., McNamee, P., Smith, B. H., Watson, M. C., Holland, R. & Wright, D. 2013 In : BMJ Open. 3, 4, e002361

    Research output: Contribution to journalArticle

  21. Predictors of QTc and QTc prolongation in the Generation Scotland Family Study

    Brown, C. E., Hastie, C. E., Alghamdi, J., Schulz, C., Hocking, L. J., Luciano, M., Porteous, D., Morris, A., Smith, B. H., Dominiczak, A. F., Tobias, E. S., Delles, C. & Padmanabhan, S. 2013 In : Journal of Human Hypertension. 27, 10, p. 639-639 1 p.

    Research output: Contribution to journalMeeting abstract

  22. Heritability of chronic pain in 2195 extended families

    Hocking, L. J., Morris, A. D., Dominiczak, A. F., Porteous, D. J., Smith, B. H. & Generation Scotland Aug 2012 In : European Journal of Pain. 16, 7, p. 1053-1063 11 p.

    Research output: Contribution to journalArticle

  23. Substance misuse of gabapentin

    Smith, B. H., Higgins, C., Baldacchino, A., Kidd, B. & Bannister, J. Aug 2012 In : British Journal of General Practice. 62, 601, p. 406-7 2 p.

    Research output: Contribution to journalArticle

  24. Epidemiology of neuropathic pain and its impact on quality of life

    Smith, B. H. & Torrance, N. 1 Jun 2012 In : Current Pain and Headache Reports. 16, 3, p. 191-198 8 p.

    Research output: Contribution to journalArticle

  25. Towards a definition of refractory neuropathic pain for epidemiological research: an international Delphi survey of experts

    Smith, B. H., Torrance, N., Ferguson, J. A., Bennett, M. I., Serpell, M. G. & Dunn, K. M. 28 May 2012 In : BMC Neurology. 12, 29

    Research output: Contribution to journalArticle

  26. "I feel so stupid because I can't give a proper answer..." How older adults describe chronic pain: a qualitative study

    Clarke, A., Anthony, G., Gray, D., Jones, D., McNamee, P., Schofield, P., Smith, B. H. & Martin, D. 2012 In : BMC Geriatrics. 12, 1, 78

    Research output: Contribution to journalArticle

  27. Alzheimer's disease risk factor complement receptor 1 is associated with depression

    Hamilton, G., Evans, K. L., MacIntyre, D. J., Deary, I. J., Dominiczak, A., Smith, B. H., Morris, A. D., Porteous, D. J. & Thomson, P. A. 2012 In : Neuroscience Letters. 510, 1, p. 6-9 4 p.

    Research output: Contribution to journalArticle

  28. Commentary: a thesis that still warrants defence and promotion

    Smith, B. H., Guthrie, B., Sullivan, F. M. & Morris, A. D. 2012 In : International Journal of Epidemiology. 41, 6, p. 1518-1522 5 p.

    Research output: Contribution to journalArticle

  29. Genetic variation in hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression

    McIntosh, A. M., Simen, A. A., Evans, K. L., Hall, J., MacIntyre, D. J., Blackwood, D., Morris, A. D., Smith, B. H., Dominiczak, A., Porteous, D., Deary, I. J. & Thomson, P. A. 2012 In : Frontiers in Genetics. 3, 00116

    Research output: Contribution to journalArticle

  30. The impact of chronic musculoskeletal pain on physical activity in older adults: implications for self-management

    Martin, D. J., Anthony, G. B., Clarke, A., Jones, D., McNamee, P., Schofield, P. A. & Smith, B. H. 2012 In : Journal of Aging and Physical Activity. 20, Supplement, p. S294-S295 2 p.

    Research output: Contribution to journalMeeting abstract

  31. Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function

    Smith, B. H. & 50 others Artigas, M. S., Wain, L. V., Repapi, E., Obeidat, M., Sayers, I., Burton, P. R., Johnson, T., Zhao, J. H., Albrecht, E., Dominiczak, A. F., Kerr, S. M., Cadby, G., Hui, J., Palmer, L. J., Hingorani, A. D., Wannamethee, S. G., Whincup, P. H., Ebrahim, S., Smith, G. D., Barroso, I., Loos, R. J. F., Wareham, N. J., Cooper, C., Dennison, E., Shaheen, S. O., Liu, J. Z., Marchini, J., Dahgam, S., Naluai, A. T., Olin, A-C., Karrasch, S., Heinrich, J., Schulz, H., McKeever, T. M., Pavord, I. D., Heliovaara, M., Ripatti, S., Surakka, I., Blakey, J. D., Kahonen, M., Britton, J. R., Nyberg, F., Holloway, J. W., Lawlor, D. A., Morris, R. W., James, A. L., Jackson, C. M., Hall, I. P., Tobin, M. D. & SpiroMeta Consortium, Med Res Council Natl Survey Hlth D 1 Oct 2011 In : American Journal of Respiratory and Critical Care Medicine. 184, 7, p. 786-795 10 p.

    Research output: Contribution to journalArticle

  32. Management of chronic pain in primary care

    Smith, B. H. & Torrance, N. Jun 2011 In : Current Opinion in Supportive and Palliative Care. 5, 2, p. 137-142 6 p.

    Research output: Contribution to journalArticle

  33. Using discrete choice experiments to inform randomised controlled trials: an application to chronic low back pain management in primary care

    Yi, D., Ryan, M., Campbell, S., Elliott, A., Torrance, N., Chambers, A., Johnston, M., Hannaford, P. & Smith, B. H. May 2011 In : European Journal of Pain. 15, 5, p. - 10 p.

    Research output: Contribution to journalArticle

  34. Potential pain management programmes in primary care: a UK-wide questionnaire and Delphi survey of experts

    Torrance, N., Smith, B. H., Elliott, A. M., Campbell, S. E., Chambers, W. A., Hannaford, P. C. & Johnston, M. Feb 2011 In : Family Practice. 28, 1, p. 41-48 8 p.

    Research output: Contribution to journalArticle

  35. NeuPSIG guidelines on neuropathic pain assessment

    Haanpaa, M., Attal, N., Backonja, M., Baron, R., Bennett, M., Bouhassira, D., Cruccu, G., Hansson, P., Haythornthwaite, J. A., Iannetti, G. D., Jensen, T. S., Kauppila, T., Nurmikko, T. J., Rice, A. S. C., Rowbotham, M., Serra, J., Sommer, C., Smith, B. H. & Treede, R-D. Jan 2011 In : PAIN. 152, 1, p. 14-27 14 p.

    Research output: Contribution to journalScientific review

  36. Is chronic pain associated with subsequent cancer?: A cohort record linkage study

    Elliott, A. M., Torrance, N., Smith, B. H. & Lee, A. J. Sep 2010 In : European Journal of Pain. 14, 8, p. 860-863 4 p.

    Research output: Contribution to journalArticle

  37. Corrigendum to Genetic variation in the beta2-adrenergic receptor but not catecholamine-O-methyltransferase predisposes to chronic pain: results from the 1958 British Birth Cohort Study (vol 149, pg 143, 2010)

    Hocking, L. J., Smith, B. H., Jones, G. T., Reid, D. M., Strachan, D. P. & Macfarlane, G. J. Jul 2010 In : PAIN. 150, 1, p. 210-210 1 p.

    Research output: Contribution to journalComment/debate

  38. Cardiovascular risk factors are increased in people reporting chronic pain symptoms

    Goodson, N. J., Smith, B. H. & Goebel, A. Apr 2010 p. I8-I8 1 p.

    Research output: Contribution to conferenceAbstract

  39. Genetic variation in the beta2-adrenergic receptor but not catecholamine-O-methyltransferase predisposes to chronic pain: results from the 1958 British Birth Cohort Study

    Hocking, L. J., Smith, B. H., Jones, G. T., Reid, D. M., Strachan, D. P. & Macfarlane, G. J. Apr 2010 In : PAIN. 149, 1, p. 143-151 9 p.

    Research output: Contribution to journalArticle

  40. Severe chronic pain is associated with increased 10 year mortality: a cohort record linkage study

    Torrance, N., Elliott, A. M., Lee, A. J. & Smith, B. H. Apr 2010 In : European Journal of Pain. 14, 4, p. 380-386 7 p.

    Research output: Contribution to journalArticle

  41. Commentary: This pain is killing me

    Smith, B. H. 1 Mar 2010 In : British Journal of General Practice. 60, 572, p. e112

    Research output: Contribution to journalComment/debate

  42. Epidemiology of neuropathic pain: what do we really know?

    Smith, B. H. 2010 3rd International Congress on Neuropathic Pain (Neupsig). Wells, C. D. (ed.). 40128 BOLOGNA: Medimond S R L, p. 79-88 10 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  43. Pharmacological management of neuropathic pain in non-specialist settings: summary of NICE guidance

    Tan, T., Barry, P., Reken, S., Baker, M. & Smith, B. 2010 In : British Medical Journal. 340, p. c1079

    Research output: Contribution to journalArticle

  44. Postsurgical pain: epidemiology

    Smith, B. H. & Bruce, J. 2010 3rd International Congress on Neuropathic Pain (Neupsig). Wells, C. D. (ed.). 40128 BOLOGNA: Medimond S R L, p. 73-78 6 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  45. Shared genetic aetiology between cognitive ability and cardiovascular disease risk factors: Generation Scotland's Scottish family health study

    Luciano, M., Batty, G. D., McGilchrist, M., Linksted, P., Fitzpatrick, B., Jackson, C., Pattie, A., Dominiczak, A. F., Morris, A. D., Smith, B. H., Porteous, D. & Deary, I. J. 2010 In : Artificial Intelligence. 38, 3, p. 304-313 10 p.

    Research output: Contribution to journalArticle

  46. A randomised controlled trial of the use of aciclovir and/or prednisolone for the early treatment of Bell's palsy: the BELLS study

    Sullivan, F. M., Swan, I. R. C., Donnan, P. T., Morrison, J. M., Smith, B., McKinstry, B., Davenport, R. J., Vale, L. D., Clarkson, J. E., Hernandez, R., Stewart, K., Hammersley, V., Hayavi, S., McAteer, A., Gray, D. & Daly, F. Oct 2009 In : Health Technology Assessment. 13, 47, p. iii-iv, ix-xi 1-130 121 p.

    Research output: Contribution to journalArticle

  47. Assessment of neuropathic pain in primary care

    Haanpaa, M. L., Backonja, M-M., Bennett, M. I., Bouhassira, D., Cruccu, G., Hansson, P. T., Jensen, T. S., Kauppila, T., Rice, A. S. C., Smith, B. H., Treede, R-D. & Baron, R. Oct 2009 In : American Journal of Medicine. 122, 10, p. S13-S21 9 p.

    Research output: Contribution to journalArticle

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