Discovery - University of Dundee - Online Publications

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Colin Henderson

  1. Defining human pathways of drug metabolism in vivo through the development of a multiple humanized mouse model

    Scheer, N., Kapelyukh, Y., Rode, A., Oswald, S., Busch, D., McLaughlin, L. A., Lin, D., Henderson, C. J. & Wolf, C. R. Nov 2015 In : Drug Metabolism and Disposition. 43, 11, p. 1679-1690 12 p.

    Research output: Contribution to journalArticle

  2. Model systems for understanding mechanisms of non-genotoxic carcinogenesis: response

    Braeuning, A., Henderson, C. J., Wolf, C. R. & Schwarz, M. Oct 2015 In : Toxicological Sciences. 147, 2, p. 299-300 2 p.

    Research output: Contribution to journalLetter

  3. Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action

    Kostov, R. V., Knatko, E. V., McLaughlin, L. A., Henderson, C. J., Zheng, S., Huang, J. T. J., Honda, T. & Dinkova-Kostova, A. T. 25 Sep 2015 In : Biochemical and Biophysical Research Communications. 465, 3, p. 402-407 6 p.

    Research output: Contribution to journalArticle

  4. Proteome-wide identification and quantification of S-glutathionylation targets in mouse liver

    McGarry, D. J., Chen, W., Chakravarty, P., Lamont, D. L., Wolf, C. R. & Henderson, C. J. Jun 2015 In : Biochemical Journal. 469, 1, p. 25-32 8 p.

    Research output: Contribution to journalArticle

  5. Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability

    Henderson, C. J., Cameron, A. R., Chatham, L., Stanley, L. A. & Wolf, C. R. May 2015 In : Toxicological Sciences. 145, 1, p. 138-148 11 p.

    Research output: Contribution to journalArticle

  6. Cytochrome b5 is a major determinant of human cytochrome P450 CYP2D6 and CYP3A4 activity in vivo

    Henderson, C. J., McLaughlin, L. A., Scheer, N., Stanley, L. A. & Wolf, C. R. Apr 2015 In : Molecular Pharmacology. 87, 4, p. 733-739 7 p.

    Research output: Contribution to journalArticle

  7. An enhanced in vivo stable isotope labeling by amino acids in cell culture (SILAC) model for quantification of drug metabolism enzymes

    MacLeod, A. K., Fallon, P. G., Sharp, S., Henderson, C. J., Wolf, C. R. & Huang, J. T-J. Mar 2015 In : Molecular & Cellular Proteomics. 14, 3, p. 750-760 11 p.

    Research output: Contribution to journalArticle

  8. Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability

    Henderson, C. J., McLaughlin, L. A., Osuna-Cabello, M., Taylor, M., Gilbert, I., McLaren, A. W. & Wolf, C. R. 1 Feb 2015 In : Biochemical Journal. 465, 3, p. 479-488 10 p.

    Research output: Contribution to journalArticle

  9. Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration

    Pajaud, J., Ribault, C., Ben Mosbah, I., Rauch, C., Henderson, C., Bellaud, P., Aninat, C., Loyer, P., Morel, F. & Corlu, A. 15 Jan 2015 In : Cell Death and Disease. 6, 13 p., e1598

    Research output: Contribution to journalArticle

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