Colin Henderson

Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver

Mutch, D. M., Crespy, V., Clough, J., Henderson, C. J., Lariani, S., Mansourian, R., Moulin, J., Wolf, C. R. & Williamson, G. Jul-2006 In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 291, 1, p. G63-G72, 10 p.

Research output: Contribution to journal › Article

Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases

Arlt, V. M., Henderson, C. J., Wolf, C. R., Schmeiser, H. H., Phillips, D. H. & Stiborova, M. 28-Mar-2006 In : Cancer Letters. 234, 2, p. 220-231, 12 p.

Research output: Contribution to journal › Article

The hepatic cytochrome P450 reductase null mouse as a tool to identify a successful candidate entity

Henderson, C. J., Pass, G. J. & Wolf, C. R. 15-Mar-2006 In : Toxicology Letters. 162, 1, p. 111-117, 7 p.

Research output: Contribution to journal › Article

Relationship between hepatic phenotype and changes in gene expression in cytochrome P450 reductase (POR) null mice

Wang, X. J., Chamberlain, M., Vassieva, O., Henderson, C. J. & Wolf, C. R. 15-Jun-2005 In : Biochemical Journal. 388, 3, p. 857-867, 11 p.

Research output: Contribution to journal › Article

Role of hepatic cytochrome P450s in the pharmacokinetics and toxicity of cyclophosphamide: studies with the hepatic cytochrome P450 reductase null mouse

Pass, G. J., Carrie, D., Boylan, M., Lorimore, S., Wright, E., Houston, B., Henderson, C. J. & Wolf, C. R. 15-May-2005 In : Cancer Research. 65, 10, p. 4211-4217, 7 p.

Research output: Contribution to journal › Article

Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H: quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols

Arlt, V. M., Stiborova, M., Henderson, C. J., Osborne, M. R., Bieler, C. A., Frei, E., Martinek, V., Sopko, B., Wolf, C. R., Schmeiser, H. H. & Phillips, D. H. 1-Apr-2005 In : Cancer Research. 65, 7, p. 2644-2652, 9 p.

Research output: Contribution to journal › Article

The murine Cyp1a1 gene is expressed in a restricted spatial and temporal pattern during embryonic development

Campbell, S. J., Henderson, C. J., Anthony, D. C., Davidson, D., Clark, A. J. & Wolf, C. R. 18-Feb-2005 In : Journal of Biological Chemistry. 280, 7, p. 5828-5835, 8 p.

Research output: Contribution to journal › Article

Transcription factor Nrf2 is essential for induction of NAD(P)H:quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates

McWalter, G. K., Higgins, L. G., McLellan, L. I., Henderson, C. J., Song, L., Thornalley, P. J., Itoh, K., Yamamoto, M. & Hayes, J. D. 1-Dec-2004 In : Journal of Nutrition. 134, 12, p. 3499S-3506S

Research output: Contribution to journal › Article

Identification of novel roles of the cytochrome P450 system in early embryogenesis: effects on vasculogenesis and retinoic acid homeostasis

Otto, D. M. E., Henderson, C. J., Carrie, D., Davey, M., Gundersen, T. E., Blomhoff, R., Adams, R. H., Tickle, C. & Wolf, C. R. Sep-2003 In : Molecular and Cellular Biology. 23, 17, p. 6103-6116, 14 p.

Research output: Contribution to journal › Article