Discovery - University of Dundee - Online Publications

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Colin Henderson

  1. Measuring in vivo responses to endogenous and exogenous oxidative stress using a novel Heme Oxygenase 1 reporter mouse

    McMahon, M., Ding, S., Acosta-Jimenez, L. P., Frangova, T. G., Henderson, C. J. & Wolf, C. R. 31 Oct 2017 In : Journal of Physiology.

    Research output: Contribution to journalArticle

  2. Xenobiotic CAR activators induce Dlk1-Dio3 locus non-coding RNA expression in mouse liver

    Pouché , L. , Vitobello, A. , Römer, M. , Glogovac, M. , MacLeod, A. K. , Ellinger-Ziegelbauer, H. , Westphal, M. , Dubost, V. , Stiehl, D. P. , Dumotier, B. , Fekete, A. , Moulin, P. , Zell, A. , Schwarz, M. , Moreno , R. , Huang, J. T. J. , Elcombe, C. R. , Henderson, C. J. , Wolf, C. R. , Moggs, J. G. & 1 others Terranova, R. Aug 2017 In : Toxicological Sciences. 158, 2, p. 367-378 11 p.

    Research output: Contribution to journalArticle

  3. Corrigendum to "Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer"

    MacLeod, A. K., Acosta-Jimenez, L., Coates, P. J., McMahon, M., Carey, F. A., Honda, T., Hayes, J. D., Henderson, C. J. & Wolf, C. R. 21 Mar 2017 In : British Journal of Cancer. 117, 1 p.

    Research output: Contribution to journalArticle

  4. Feedback control of AHR signalling regulates intestinal immunity

    Schiering, C., Wincent, E., Metidji, A., Iseppon, A., Li, Y., Potocnik, A. J., Omenetti, S., Henderson, C. J., Wolf, C. R., Nebert, D. W. & Stockinger, B. 9 Feb 2017 In : Nature. 542, 7640, p. 242-245 4 p.

    Research output: Contribution to journalLetter

  5. Aryl hydrocarbon receptor is required for optimal B-cell proliferation

    Villa, M., Gialitakis, M., Tolaini, M., Ahlfors, H., Henderson, C. J., Wolf, C. R., Brink, R. & Stockinger, B. 4 Jan 2017 In : EMBO Journal. 36, 1, p. 116-128 13 p.

    Research output: Contribution to journalArticle

  6. Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer

    MacLeod, A. K., Acosta-Jimenez, L., Coates, P. J., McMahon, M., Carey, F. A., Honda, T., Henderson, C. J. & Wolf, C. R. 6 Dec 2016 In : British Journal of Cancer. 115, 12, p. 1530-1539 10 p.

    Research output: Contribution to journalArticle

  7. Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans

    Takahashi, S., Fukami, T., Masuo, Y., Brocker, C. N., Xie, C., Krausz, K. W., Wolf, C. R., Henderson, C. J. & Gonzalez, F. J. Dec 2016 In : Journal of Lipid Research. 57, p. 2130-2037 8 p.

    Research output: Contribution to journalArticle

  8. Olaparib, monotherapy or with ionizing radiation, exacerbates DNA damage in normal tissues: insights from a new p21 reporter mouse

    McMahon, M., Frangova, T. G., Henderson, C. J. & Wolf, C. R. Dec 2016 In : Molecular Cancer Research. 14, 12, p. 1195-1203 9 p.

    Research output: Contribution to journalArticle

  9. Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

    Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J. 20 Nov 2016 New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January, p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  10. Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π

    McMillan, D. H. , van der Velden, J. L. J. , Lahue, K. G. , Quan, X. , Schneider, R. W. , Iberg, M. S. , Nolin, J. D. , Abdalla, S. , Casey, D. T. , Tew, K. D. , Townsend, D. M. , Henderson, C. J. , Wolf, C. R. , Butnor, K. J. , Taatjes, D. J. , Budd, R. C. , Irvin, C. G. , van der Vliet, A. , Flemer, S. , Anathy, V. & 1 others Janssen-Heininger, Y. M. W. 2 Jun 2016 In : JCI Insight. 1, 8, 16 p., e85717

    Research output: Contribution to journalArticle

  11. The role of protein-protein and protein-membrane Interactions on P450 function

    Scott, E. E., Wolf, C. R., Otyepka, M., Humphreys, S. C., Reed, J. R., Henderson, C. J., McLaughlin, L. A., Paloncyova, M., Navratilova, V., Berka, K., Anzenbacher, P., Dahal, U. P., Barnaba, C., Brozik, J. A., Jones, J. P., Estrada, F., Laurence, J. S., Park, J. W. & Backes, W. L. Apr 2016 In : Drug Metabolism and Disposition. 44, 4, p. 576-590 15 p.

    Research output: Contribution to journalArticle

  12. Activation status of the Pregnane X Receptor influences Vemurafenib availability in humanized mouse models

    MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R. 1 Nov 2015 In : Cancer Research. 75, 21, p. 4573-4581 10 p.

    Research output: Contribution to journalArticle

  13. Defining human pathways of drug metabolism in vivo through the development of a multiple humanized mouse model

    Scheer, N., Kapelyukh, Y., Rode, A., Oswald, S., Busch, D., McLaughlin, L. A., Lin, D., Henderson, C. J. & Wolf, C. R. Nov 2015 In : Drug Metabolism and Disposition. 43, 11, p. 1679-1690 12 p.

    Research output: Contribution to journalArticle

  14. Model systems for understanding mechanisms of non-genotoxic carcinogenesis: response

    Braeuning, A., Henderson, C. J., Wolf, C. R. & Schwarz, M. Oct 2015 In : Toxicological Sciences. 147, 2, p. 299-300 2 p.

    Research output: Contribution to journalLetter

  15. Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action

    Kostov, R. V., Knatko, E. V., McLaughlin, L. A., Henderson, C. J., Zheng, S., Huang, J. T. J., Honda, T. & Dinkova-Kostova, A. T. 25 Sep 2015 In : Biochemical and Biophysical Research Communications. 465, 3, p. 402-407 6 p.

    Research output: Contribution to journalArticle

  16. Proteome-wide identification and quantification of S-glutathionylation targets in mouse liver

    McGarry, D. J., Chen, W., Chakravarty, P., Lamont, D. L., Wolf, C. R. & Henderson, C. J. Jun 2015 In : Biochemical Journal. 469, 1, p. 25-32 8 p.

    Research output: Contribution to journalArticle

  17. Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability

    Henderson, C. J., Cameron, A. R., Chatham, L., Stanley, L. A. & Wolf, C. R. May 2015 In : Toxicological Sciences. 145, 1, p. 138-148 11 p.

    Research output: Contribution to journalArticle

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