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Gillian Smith

  1. Evidence that serine 304 is not a key ligand-binding residue in the active site of cytochrome P450 2D6

    Ellis, S. W., Hayhurst, G. P., Lightfoot, T., Smith, G., Harlow, J., Rowland-Yeo, K., Larsson, C., Mahling, J., Lim, C. K., Wolf, C. R., Blackburn, M. G., Lennard, M. S. & Tucker, G. T. 2000 In : Biochemical Journal. 345 , 3, p. 565-571 7 p.

    Research output: Contribution to journalArticle

  2. Pharmacogenetics

    Wolf, C. R., Smith, G. & Smith, R. L. 2000 In : British Medical Journal. 320, 7240, p. 987-90 4 p.

    Research output: Contribution to journalArticle

  3. Adaptive responses to environmental chemicals

    Wolf, C. R., Smith, G., Smith, A. G., Brown, K. & Henderson, C. J. 1999 Cellular responses to stress. Downes, C. P., Wolf, C. R. & Lane, D. P. (eds.). London: Portland Press Ltd, p. 129-139 11 p. (Biochemical Society symposia; no. 64)

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  4. Cytochrome P450 CYP2D6

    Wolf, C. R. & Smith, G. 1999 In : IARC Scientific Publications. 148, p. 209-29 21 p.

    Research output: Contribution to journalArticle

  5. Pharmacogenetics

    Wolf, C. R. & Smith, G. 1999 In : British Medical Bulletin. 55, 2, p. 366-86 21 p.

    Research output: Contribution to journalArticle

  6. Determinants of the substrate specificity of human cytochrome P-450 CYP2D6: design and construction of a mutant with testosterone hydroxylase activity

    Smith, G., Modi, S., Pillai, I., Lian, L-Y., Sutcliffe, M. J., Pritchard, M. P., Friedberg, T., Roberts, G. C. K. & Wolf, C. R. 1998 In : Biochemical Journal. 331 , 3, p. 783-792 10 p.

    Research output: Contribution to journalArticle

  7. Molecular genetics of the human cytochrome P450 monooxygenase superfamily

    Smith, G., Stubbins, M. J., Harries, L. W. & Wolf, C. R. 1998 In : Xenobiotica. 28, 12, p. 1129-1165 37 p.

    Research output: Contribution to journalArticle

  8. Genetic structural and functional analysis of cytochrome P450s in the CYP2D gene family

    Wolf, C. R., Modi, S., Lian, L. Y., Paine, M., Smith, G. & Roberts, G. C. K. 31 Jul 1997 In : FASEB Journal. 11, 9, p. A773-A773 1 p., P25

    Research output: Contribution to journalMeeting abstract

  9. Active site models of human cytochrome P450s based on NMR relaxation measurements

    Modi, S., Paine, M. J., Oliver, C. F., Smith, G., Sutcliffe, M. J., Gilham, D. E., Shaw, A. N. J., Lian, L. Y., Primrose, W. U., Wolf, C. R. & Roberts, G. C. K. 1997 In : FASEB Journal. 11, 9, p. A771-A771 1 p.

    Research output: Contribution to journalMeeting abstract

  10. Active-site topologies of human CYP2D6 and its aspartate-301 → glutamate, asparagine, and glycine mutants

    Mackman, R., Tschirret-Guth, R. A., Smith, G., Hayhurst, G. P., Ellis, S. W., Lennard, M. S., Tucker, G. T., Wolf, C. R. & Ortiz de Montellano, P. R. 1996 In : Archives of Biochemistry and Biophysics. 331, 1, p. 134-140 7 p.

    Research output: Contribution to journalArticle

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