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Gillian Smith

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  1. Determinants of the substrate specificity of human cytochrome P-450 CYP2D6: design and construction of a mutant with testosterone hydroxylase activity

    Smith, G., Modi, S., Pillai, I., Lian, L-Y., Sutcliffe, M. J., Pritchard, M. P., Friedberg, T., Roberts, G. C. K. & Wolf, C. R. 1998 In : Biochemical Journal. 331 , 3, p. 783-792 10 p.

    Research output: Contribution to journalArticle

  2. Molecular genetics of the human cytochrome P450 monooxygenase superfamily

    Smith, G., Stubbins, M. J., Harries, L. W. & Wolf, C. R. 1998 In : Xenobiotica. 28, 12, p. 1129-1165 37 p.

    Research output: Contribution to journalArticle

  3. Genetic structural and functional analysis of cytochrome P450s in the CYP2D gene family

    Wolf, C. R., Modi, S., Lian, L. Y., Paine, M., Smith, G. & Roberts, G. C. K. 31 Jul 1997 In : FASEB Journal. 11, 9, p. A773-A773 1 p.P25

    Research output: Contribution to journalMeeting abstract

  4. Active site models of human cytochrome P450s based on NMR relaxation measurements

    Modi, S., Paine, M. J., Oliver, C. F., Smith, G., Sutcliffe, M. J., Gilham, D. E., Shaw, A. N. J., Lian, L. Y., Primrose, W. U., Wolf, C. R. & Roberts, G. C. K. 1997 In : FASEB Journal. 11, 9, p. A771-A771 1 p.

    Research output: Contribution to journalMeeting abstract

  5. Active-site topologies of human CYP2D6 and its aspartate-301 → glutamate, asparagine, and glycine mutants

    Mackman, R., Tschirret-Guth, R. A., Smith, G., Hayhurst, G. P., Ellis, S. W., Lennard, M. S., Tucker, G. T., Wolf, C. R. & Ortiz de Montellano, P. R. 1996 In : Archives of Biochemistry and Biophysics. 331, 1, p. 134-140 7 p.

    Research output: Contribution to journalArticle

  6. Genetic analysis of the human cytochrome P450 CYP2C9 locus

    Stubbins, M. J., Harries, L. W., Smith, G., Tarbit, M. H. & Wolf, C. R. 1996 In : Pharmacogenetics. 6, 5, p. 429-39 11 p.

    Research output: Contribution to journalArticle

  7. Characterization of anti-LKM-antibody targets in patients with autoimmune hepatitis typ2 and hepatitis-C

    Thalhammer, T., Smith, G., Wolf, H., Wolf, R., Boltznitulescu, G., Dopplinger, C. & Penner, E. 1995 In : FASEB Journal. 9, 3, p. A146 1 p.851

    Research output: Contribution to journalMeeting abstract

  8. Evidence that aspartic acid 301 is a critical substrate-contact residue in the active site of cytochrome P450 2D6

    Ellis, S. W., Hayhurst, G. P., Smith, G., Lightfoot, T., Wong, M. M. S., Simula, A. P., Ackland, M. J., Sternberg, M. J. E., Lennard, M. S., Tucker, G. T. & Wolf, C. R. 1995 In : Journal of Biological Chemistry. 270, 49, p. 29055-29058 4 p.

    Research output: Contribution to journalComment/debate

  9. Metabolic polymorphisms and cancer susceptibility

    Smith, G., Stanley, L. A., Sim, E., Strange, R. C. & Wolf, C. R. 1995 In : Cancer Surveys. 25, p. 27-65 39 p.

    Research output: Contribution to journalArticle

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