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Gillian Smith

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  1. Glutathione S-transferase P1 (GSTP1) directly influences platinum drug chemosensitivity in ovarian tumour cell lines

    Sawers, L., Ferguson, M. J., Ihrig, B. R., Young, H. C., Chakravarty, P., Wolf, C. R. & Smith, G. 2014 In : British Journal of Cancer.

    Research output: Contribution to journalArticle

  2. Cytochrome P450 CYP1B1 Interacts with 8-Methoxypsoralen (8-MOP) and Influences Psoralen-Ultraviolet A (PUVA) Sensitivity

    Deeni, Y. Y., Ibbotson, S. H., Woods, J. A., Wolf, C. R. & Smith, G. 23 Sep 2013 In : PLoS ONE. 8, 9, e75494

    Research output: Contribution to journalArticle

  3. Cytochrome P450 CYP1B1 interacts with 8-methoxypsoralen (8-MOP) and influences psoralen-ultraviolet (PUVA) sensitivity

    Deeni, Y. Y., Ibbotson, S. H., Woods, J. A., Wolf, C. R. & Smith, G. 2013 In : PLoS ONE. 8, 9, e75494

    Research output: Contribution to journalArticle

  4. Individuality in FGF1 expression significantly influences platinum resistance and progression-free survival in ovarian cancer

    Smith, G., Ng, M. T. H., Shepherd, L., Herrington, C. S., Gourley, C., Ferguson, M. & Wolf, C. R. 9 Oct 2012 In : British Journal of Cancer. 107, 8, p. 1327-1336 10 p.

    Research output: Contribution to journalArticle

  5. Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1

    McNeilly, A. D., Woods, J. A., Ibbotson, S. H., Wolf, C. R. & Smith, G. Feb 2012 In : Drug Metabolism and Disposition. 40, 2, p. 283-289 7 p.

    Research output: Contribution to journalArticle

  6. Glutathione S-transferase genotype is associated with sensitivity to psoralen-ultraviolet A photochemotherapy

    Ibbotson, S. H., Dawe, R. S., Dinkova-Kostova, A. T., Weidlich, S., Farr, P. M., Ferguson, J., Wolf, C. R. & Smith, G. Feb 2012 In : British Journal of Dermatology. 166, 2, p. 380-388 9 p.

    Research output: Contribution to journalArticle

  7. Pyrosequencing-based methods reveal marked inter-individual differences in oncogene mutation burden in human colorectal tumours

    Weidlich, S., Walsh, K., Crowther, D., Burczynski, M. E., Feuerstein, G., Carey, F., Steele, R. J. C., Wolf, C. R., Miele, G. & Smith, G. 12 Jul 2011 In : British Journal of Cancer. 105, 2, p. 246-254 9 p.

    Research output: Contribution to journalArticle

  8. Glutathione S-transferase M1 (GSTM1) genotype but not GSTT1 or MC1R genotype influences erythemal sensitivity to narrow band (TL-01) UVB phototherapy

    Smith, G., Weidlich, S., Dawe, R. S. & Ibbotson, S. H. Apr 2011 In : Pharmacogenetics and Genomics. 21, 4, p. 217-224 8 p.

    Research output: Contribution to journalArticle

  9. Activating K-Ras mutations outwith "hotspot" codons in sporadic colorectal tumours: implications for personalised cancer medicine

    Smith, G., Bounds, R., Wolf, H., Pratt, N., Carey, F., Steele, R. & Wolf, C. Sep 2010 In : Journal of Pathology. 222, S1, p. S12-S12 1 p.

    Research output: Contribution to journalBook/Film/Article review

  10. Glutathione S-transferase M1 (GSTM1) genotype is associated with serum 8-MOP concentration and PUVA sensitivity

    Ibbotson, S. H., Dawe, R. S., Weidlich, S., Dinkova-Kostova, A. T., Farr, P. M., Ferguson, J., Wolf, C. R. & Smith, G. Apr 2010 In : British Journal of Dermatology. 162, 4, p. 941-941 1 p.

    Research output: Contribution to journalMeeting abstract

  11. Activating K-Ras mutations outwith 'hotspot' codons in sporadic colorectal tumours: implications for personalised cancer medicine

    Smith, G., Bounds, R., Wolf, H., Steele, R., Carey, F. & Wolf, R. 16 Feb 2010 In : British Journal of Cancer. 102, 4, p. 693-703 11 p.

    Research output: Contribution to journalArticle

  12. Polymorphisms in xenobiotic metabolizing enzymes and diet influence colorectal adenoma risk

    Northwood, E. L., Elliott, F., Forman, D., Barrett, J. H., Wilkie, M. J. V., Carey, F. A., Steele, R. J. C., Wolf, R., Bishop, T. & Smith, G. 2010 In : Pharmacogenetics and Genomics. 20, 5, p. 315-326 12 p.

    Research output: Contribution to journalArticle

  13. Genetic Variants in XRCC2: New Insights Into Colorectal Cancer Tumorigenesis

    Curtin, K., Lin, W-Y., George, R., Katory, M., Shorto, J., Cannon-Albright, L. A., Smith, G., Bishop, D. T., Cox, A., Camp, N. J. & Colorectal Canc Study Grp Sep 2009 In : Cancer Epidemiology, Biomarkers & Prevention. 18, 9, p. 2476-2484 9 p.

    Research output: Contribution to journalArticle

  14. Glutathione S-transferase M1 genotype is associated with erythemal sensitivity to narrowband ultraviolet B in patients with psoriasis

    Ibbotson, S. H., Weidlich, S., Ferguson, J., Wolf, R., Dawe, R. S. & Smith, G. Apr 2009 In : British Journal of Dermatology. 160, 4, p. 928-928 1 p.

    Research output: Contribution to journalArticle

  15. Polymorphisms in the SLC6A4 and HTR2A genes influence treatment outcome following antidepressant therapy

    Wilkie, M. J. V., Smith, G., Day, R., Matthews, K., Smith, D., Blackwood, D., Reid, I. C. & Wolf, R. 2009 In : Pharmacogenomics Journal. 9, 1, p. 61-70 10 p.

    Research output: Contribution to journalArticle

  16. Methylene tetrahydrofolate reductase genotype modifies the chemopreventive effect of folate in colorectal adenoma, but not colorectal cancer

    Lightfoot, T. J., Barrett, J. H., Bishop, T., Northwood, E. L., Smith, G., Wilkie, M. J. V., Steele, R. J. C., Carey, F. A., Key, T. J., Wolf, R. & Forman, D. Sep 2008 In : Cancer Epidemiology, Biomarkers & Prevention. 17, 9, p. 2421-2430 10 p.

    Research output: Contribution to journalArticle

  17. DUSP6/MKP-3 expression and K-ras mutation in colorectal cancer

    Conlin, A., Smith, G., Steele, R. J. C. & Wolf, C. R. Mar 2008 In : Gut. 57, Supplement 1, p. A134-A134 1 p.350

    Research output: Contribution to journalBook/Film/Article review

  18. Melanocortin 1 receptor (MC1R) genotype influences erythemal sensitivity to psoralen-ultraviolet A photochemotherapy

    Smith, G., Wilkie, M. J. V., Deeni, Y. Y., Farr, P. M., Ferguson, J., Wolf, C. R. & Ibbotson, S. H. Dec 2007 In : British Journal of Dermatology. 157, 6, p. 1230-4 5 p.

    Research output: Contribution to journalArticle

  19. A splice site polymorphism in the G-protein beta subunit influences antidepressant efficacy in depression

    Wilkie, M. J. V., Smith, D., Reid, I. C., Day, R. K., Matthews, K., Wolf, R., Blackwood, D. & Smith, G. Mar 2007 In : Pharmacogenetics and Genomics. 17, 3, p. 207-215 9 p.

    Research output: Contribution to journalArticle

  20. Can dietary furanocoumarin ingestion enhance the erythemal response during high-dose UVA1 therapy?

    Beattie, P. E., Wilkie, M. J. V., Smith, G., Ferguson, J. & Ibbotson, S. Jan 2007 In : Journal of the American Academy of Dermatology. 56, 1, p. 84-87 4 p.

    Research output: Contribution to journalArticle

  21. Genetic factors associated with the aetiology and treatment of colorectal cancer

    Wolf, C. R., Steele, R. J. C., Carey, F. A., Pratt, N. D., Bishop, D. T., Barrett, J. H., Forman, D. & Smith, G. 1 Sep 2006 In : Toxicology. 226, 1, p. 14-14 1 p.

    Research output: Contribution to journalMeeting abstract

  22. Inter- and intrasubject variation in cytoprotective gene expression in patients with psoriasis

    Smith, G., Hearn, R., Wolf, C. R., Ferguson, J. & Ibbotson, S. H. Jul 2006 In : British Journal of Dermatology. 155, 1, p. 254-254 1 p.P26

    Research output: Contribution to journalMeeting abstract

  23. Melanocortin 1 receptor genotype influences erythemal sensitivity and treatment response in patients undergoing psoralen plus ultraviolet A treatment

    Smith, G., Wilkie, M. J. V., Deeni, Y. Y., Ferguson, J., Wolf, C. R. & Ibbotson, S. H. Jul 2006 In : British Journal of Dermatology. 155, 1, p. 240-240 1 p.O15

    Research output: Contribution to journalMeeting abstract

  24. Chromosomal changes in colorectal adenomas: relationship to gene mutations and potential for clinical utility

    Leslie, A., Stewart, A., Baty, D. U., Mechan, D., McGreavey, L., Smith, G., Wolf, C. R., Sales, M., Pratt, N. R., Steele, R. J. C. & Carey, F. A. Feb 2006 In : Genes, Chromosomes and Cancer. 45, 2, p. 126-135 10 p.

    Research output: Contribution to journalArticle

  25. Identification of CYP2S1 ligands

    Dickmann, L. J., Deeni, Y., Smith, G. & Wolf, C. R. 2006 In : Drug Metabolism Reviews. 38, Suppl., p. 56-56 1 p.

    Research output: Contribution to journalMeeting abstract

  26. Identification of CYP2S1 ligands

    Dickmann, L. J., Deeni, Y., Smith, G. & Wolf, C. R. 2006

    Research output: Contribution to conferenceAbstract

  27. Regulation of cutaneous drug-metabolizing enzymes and cytoprotective gene expression by topical drugs in human skin in vivo

    Smith, G., Ibbotson, S. H., Comrie, M. M., Dawe, R. S., Bryden, A., Ferguson, J. & Wolf, C. R. 2006 In : British Journal of Dermatology. 155, 2, p. 275-81 7 p.

    Research output: Contribution to journalArticle

  28. Mutation and tissue microarray analysis of tumour suppressor genes and cell cycle-related proteins in colorectal cancer

    Robertson, K. E., Conlin, A., Miller, J., Smith, G., Steele, R. J. C., Wolf, C. R., Levison, D. A. & Carey, F. A. 2005 In : Journal of Pathology. 207, Suppl. 1, p. 43-43 1 p.

    Research output: Contribution to journalMeeting abstract

  29. Mutation and tissue microarray analysis of tumour suppressor genes and cell cycle-related proteins in colorectal cancer

    Robertson, K. E., Conlin, A., Miller, J., Smith, G., Steele, R. J. C., Wolf, C. R., Levison, D. A. & Carey, F. A. 2005

    Research output: Contribution to conferenceAbstract

  30. No evidence that polymorphisms in CYP2C8, CYP2C9, UGT1A6, PPAR[delta] and PPAR[gamma] act as modifiers of the protective effect of regular NSAID use on the risk of colorectal carcinoma

    McGreavey, L. E., Turner, F., Smith, G., Boylan, K., Bishop, D. T., Forman, D., Wolf, C. R. & Barrett, J. H. 2005 In : Pharmacogenetics and Genomics. 15, 10, p. 713-721 9 p.

    Research output: Contribution to journalArticle

  31. The prognostic significance of K-ras, p53, and APC mutations in colorectal carcinoma

    Conlin, A., Smith, G., Carey, F. A., Wolf, C. R. & Steele, R. J. C. 2005 In : Gut. 54, 9, p. 1283-1286 4 p.

    Research output: Contribution to journalArticle

  32. Vegetable, fruit and meat consumption and potential risk modifying genes in relation to colorectal cancer

    Turner, F., Smith, G., Sachse, C., Lightfoot, T., Garner, R. C., Wolf, C. R., Forman, D., Bishop, D. T., Barrett, J. H. & Colorectal Cancer Study Group 1 Nov 2004 In : International Journal of Cancer. 112, 2, p. 259-264 6 p.

    Research output: Contribution to journalArticle

  33. Regulation of cytochrome P450 CYP2S1 in human skin by UVR and topical drugs used to treat psoriasis

    Smith, G., Deeni, Y. Y., Dawe, R. S., Evans, A. T., Ferguson, J., Wolf, C. R. & Ibbotson, S. H. Aug 2004 In : Drug Metabolism Reviews. 36, Supplement 1, p. 181-181 1 p.363

    Research output: Contribution to journalMeeting abstract

  34. No association of polymorphisms in CYP17, CYP19, and HSD17-B1 with plasma estradiol concentrations in 1,090 British women

    Travis, R. C., Churchman, M., Edwards, S. A., Smith, G., Verkasalo, P. K., Wolf, C. R., Wolf, H. & Key, T. J. 2004 In : Cancer Epidemiology, Biomarkers & Prevention. 13, 12, p. 2282-4 3 p.

    Research output: Contribution to journalArticle

  35. Phenotyping of N-acetyltransferase type 2 by caffeine from uncontrolled dietary exposure

    Jetter, A., Kinzig-Schippers, M., Illauer, M., Hermann, R., Erb, K., Borlak, J., Wolf, H., Smith, G., Cascorbi, I., Sorgel, F. & Fuhr, U. 2004 In : European Journal of Clinical Pharmacology. 60, 1, p. 17-21 5 p.

    Research output: Contribution to journalArticle

  36. Mutations of APC, K-ras, and p53 are associated with specific chromosomal aberrations in colorectal adenocarcinomas

    Leslie, A., Pratt, N. R., Gillespie, K., Sales, M., Kernohan, N. M., Smith, G., Wolf, C. R., Carey, F. A. & Steele, R. J. C. Aug 2003 In : Cancer Research. 63, 15, p. 4656-4661 6 p.

    Research output: Contribution to journalArticle

  37. Quantitative real-time reverse transcription-polymerase chain reaction analysis of drug metabolizing and cytoprotective genes in psoriasis and regulation by ultraviolet radiation

    Smith, G., Dawe, R. S., Clark, C., Evans, A. T., Comrie, M. M., Wolf, C. R., Ferguson, J. & Ibbotson, S. H. Aug 2003 In : Journal of Investigative Dermatology. 121, 2, p. 390-398 9 p.

    Research output: Contribution to journalArticle

  38. Cytochrome P450 CYP2S1 expression in human skin: individuality in regulation by therapeutic agents for psoriasis and other skin diseases

    Smith, G., Deeni, Y. Y., Dawe, R. S., Comrie, M. M., Wolf, C. R., Ferguson, J. & Ibbotson, S. H. Apr 2003 In : British Journal of Dermatology. 148, 4, p. 853-853 1 p.O16

    Research output: Contribution to journalMeeting abstract

  39. Cutaneous expression of cytochrome P450 CYP2S1: individuality in regulation by therapeutic agents for psoriasis and other skin diseases

    Smith, G., Wolf, C. R., Deeni, Y. Y., Dawe, R. S., Evans, A. T., Comrie, M. M., Ferguson, J. & Ibbotson, S. H. 2003 In : Lancet. 361, 9366, p. 1336-1343 8 p.

    Research output: Contribution to journalArticle

  40. Investigation of interaction between N-acetyltransferase 2 and heterocyclic amines as potential risk factors for colorectal cancer

    Barrett, J. H., Smith, G., Waxman, R., Gooderham, N., Lightfoot, T., Garner, R. C., Augustsson, K., Wolf, C. R., Bishop, D. T. & Forman, D. 2003 In : Carcinogenesis. 24, 2, p. 275-282 8 p.

    Research output: Contribution to journalArticle

  41. Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism

    Sachse, C., Bhambra, U., Smith, G., Lightfoot, T. J., Barrett, J. H., Scollay, J., Garner, R. C., Boobis, A. R., Wolf, C. R., Gooderham, N. J. & Colorectal Cancer Study Group 2003 In : British Journal of Clinical Pharmacology. 55, 1, p. 68-76 9 p.

    Research output: Contribution to journalArticle

  42. Topical coal tar and all-trans retinoic acid modulate drug metabolising gene expression in human skin in vivo

    Ibbotson, S. H., Smith, G., Sawe, R. S., Comrie, M. M., Bryden, A., Wolf, C. E. & Ferguson, J. 2003 In : British Journal of Dermatology. 148, 4, p. 861-861 1 p.P15

    Research output: Contribution to journalMeeting abstract

  43. Topical coal tar and all-trans retinoic acid modulate drug metabolising gene expression in human skin in vivo

    Ibbotson, S. H., Smith, G., Sawe, R. S., Comrie, M. M., Bryden, A., Wolf, C. E. & Ferguson, J. 2003

    Research output: Contribution to conferencePoster

  44. A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer

    Sachse, C., Smith, G., Wilkie, M. J. V., Barrett, J. H., Waxman, R., Sullivan, F., Forman, D., Bishop, D. T., Wolf, C. R. & Colorectal Cancer Study Group Nov 2002 In : Carcinogenesis. 23, 11, p. 1839-49 11 p.

    Research output: Contribution to journalArticle

  45. Expression and regulation of cytoprotective genes by ultraviolet radiation in skin of patients with psoriasis

    Smith, G., Dawe, R. S., Evans, A. T., Comrie, M. M., Ferguson, J., Wolf, C. R. & Ibbotson, S. H. Sep 2002 In : Journal of Investigative Dermatology. 119, 3, p. 740-740 1 p.166

    Research output: Contribution to journalMeeting abstract

  46. Chromosomal abnormality and gene mutation in sporadic colorectal cancer

    Leslie, A., Smith, G., Pratt, N. R., Carey, F. A., Wolf, C. R. & Steele, R. J. C. 2002 In : British Journal of Surgery. 89, 5, p. 663-664 2 p.

    Research output: Contribution to journalMeeting abstract

  47. Factors influencing the cellular accumulation of SN-38 and camptothecin

    Cummings, J., Boyd, G., Macpherson, J. S., Wolf, H., Smith, G., Smyth, J. F. & Jodrell, D. I. 2002 In : Cancer Chemotherapy and Pharmacology. 49, 3, p. 194-200 7 p.

    Research output: Contribution to journalArticle

  48. Mutations in APC, Kirsten-ras, and p53—alternative genetic pathways to colorectal cancer

    Smith, G., Carey, F. A., Beattie, J., Wilkie, M. J. V., Lightfoot, T. J., Coxhead, J., Garner, R. C., Steele, R. J. C. & Wolf, C. R. 2002 In : Proceedings of the National Academy of Sciences of the United States of America. 99, 14, p. 9433-9438 6 p.

    Research output: Contribution to journalArticle

  49. Relation of mismatch repair protein status with mutational and chromosomal abnormalities in colorectal cancer

    Allen, D., Smith, G., Steele, R. J. C., Wolf, C. R. & Carey, F. A. 2002 In : Journal of Pathology. 198, 1, p. 34A-34A 1 p.

    Research output: Contribution to journalMeeting abstract

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