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John Hayes

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  1. Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms

    Gupta, K., Patani, R., Baxter, P., Serio, A., Story, D., Tsujita, T., Hayes, J. D., Pedersen, R. A., Hardingham, G. E. & Chandran, S. May-2012 In : Cell Death & Differentiation. 19, 5, p. 779-787, 9 p.

    Research output: Contribution to journal › Article

  2. Peptide inhibitors of the Keap1-Nrf2 protein-protein interaction

    Hancock, R., Bertrand, H. C., Tsujita, T., Naz, S., El-Bakry, A., Laoruchupong, J., Hayes, J. D. & Wells, G. 15-Jan-2012 In : Free Radical Biology and Medicine. 52, 2, p. 444-451, 8 p.

    Research output: Contribution to journal › Article

  3. Analysis of the role of Nrf2 in the expression of liver proteins in mice using two-dimensional gel-based proteomics

    Abdullah, A., Kitteringham, N. R., Jenkins, R. E., Goldring, C., Higgins, L., Yamamoto, M., Hayes, J. & Park, B. K. 2012 In : Pharmacological Reports. 64, 3, p. 680-697, 18 p.

    Research output: Contribution to journal › Article

  4. Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

    Chowdhry, S., Zhang, Y., McMahon, M., Sutherland, C., Cuadrado, A. & Hayes, J. D. 2012 In : Oncogene.

    Research output: Contribution to journal › Article

  5. Nrf2 orchestrates fuel partitioning for cell proliferation

    Hayes, J. D. & Ashford, M. L. J. 2012 In : Cell Metabolism. 16, 2, p. 139-141, 3 p.

    Research output: Contribution to journal › Article

  6. Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP Axis

    Rada, P., Rojo, A. I., Evrard-Todeschi, N., Innamorato, N. G., Cotte, A., Jaworski, T., Tobón-Velasco, J. C., Devijver, H., García-Mayoral, M. F., Van Leuven, F., Hayes, J. D., Bertho, G. & Cuadrado, A. 2012 In : Molecular and Cellular Biology. 32, 17, p. 3486-99, 14 p.

    Research output: Contribution to journal › Article

  7. Nrf2-mediated induction of antioxidant response element-driven gene expression by flavonoids is dependent on their chemical structure

    Xiao, H., Hourihan, J. M., Brown, L., McMahon, M., Stewart, D. & Hayes, J. D. 18-Dec-2011 In : Toxicology. 290, 2-3, p. 126-127, 2 p.

    Research output: Contribution to journal › Book/Film/Article review

  8. The cap'n'collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics

    Higgins, L. G. & Hayes, J. D. 30-Jun-2011 In : Chemico-Biological Interactions. 192, 1-2, p. 37-45, 9 p.

    Research output: Contribution to journal › Article

  9. Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents

    Higgins, L. G. & Hayes, J. D. May-2011 In : Drug Metabolism Reviews. 43, 2, p. 92-137, 46 p.

    Research output: Contribution to journal › Scientific review

  10. SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner

    Rada, P., Rojo, A. I., Chowdhry, S., McMahon, M., Hayes, J. D. & Cuadrado, A. Mar-2011 In : Molecular and Cellular Biology. 31, 6, p. 1121-1133, 13 p.

    Research output: Contribution to journal › Article

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