Discovery - University of Dundee - Online Publications

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Michael McMahon

  1. Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

    Chowdhry, S., Zhang, Y., McMahon, M., Sutherland, C., Cuadrado, A. & Hayes, J. D. 2012 In : Oncogene. 32, p. 3765-3781 17 p.

    Research output: Contribution to journalArticle

  2. Nrf2-mediated induction of antioxidant response element-driven gene expression by flavonoids is dependent on their chemical structure

    Xiao, H., Hourihan, J. M., Brown, L., McMahon, M., Stewart, D. & Hayes, J. D. 18 Dec 2011 In : Toxicology. 290, 2-3, p. 126-127 2 p.

    Research output: Contribution to journalBook/Film/Article review

  3. SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner

    Rada, P., Rojo, A. I., Chowdhry, S., McMahon, M., Hayes, J. D. & Cuadrado, A. Mar 2011 In : Molecular and Cellular Biology. 31, 6, p. 1121-1133 13 p.

    Research output: Contribution to journalArticle

  4. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription

    Jain, A., Lamark, T., Sjottem, E., Larsen, K. B., Awuh, J. A., Overvatn, A., McMahon, M., Hayes, J. D. & Johansen, T. 16 Jul 2010 In : Journal of Biological Chemistry. 285, 29, p. 22576-22591 16 p.

    Research output: Contribution to journalArticle

  5. Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway

    Hayes, J. D., McMahon, M., Chowdhry, S. & Dinkova-Kostova, A. T. 2010 In : Antioxidants & Redox Signaling. 13, 11, p. 1713-1748 36 p.

    Research output: Contribution to journalArticle

  6. 1-Cyano-2,3-epithiopropane is a novel plant-derived chemopreventive agent which induces cytoprotective genes that afford resistance against the genotoxic alpha,beta-unsaturated aldehyde acrolein

    Kelleher, M. O., McMahon, M., Eggleston, I. M., Dixon, M. J., Taguchi, K., Yamamoto, M. & Hayes, J. D. Oct 2009 In : Carcinogenesis. 30, 10, p. 1754-1762 9 p.

    Research output: Contribution to journalArticle

  7. NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

    Hayes, J. D. & McMahon, M. Apr 2009 In : Trends in Biochemical Sciences. 34, 4, p. 176-188 13 p.

    Research output: Contribution to journalScientific review

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