Roland Wolf

Generation and characterization of a novel multidrug resistance protein 2 humanized mouse line

Scheer, N., Balimane, P., Hayward, M. D., Buechel, S., Kauselmann, G. & Wolf, C. R. 2012 In : Drug Metabolism and Disposition. 40, 11, p. 2212-2218, 7 p.

Research output: Contribution to journal › Article

Tauroursodeoxycholic acid prevents MPTP-induced dopaminergic cell death in a mouse model of Parkinson's disease

Castro-Caldas, M., Carvalho, A. N., Rodrigues, E., Henderson, C. J., Wolf, C. R., Rodrigues, C. M. P. & Gama, M. J. 2012 In : Molecular Neurobiology. 46, 2, p. 475-486, 12 p.

Research output: Contribution to journal › Article

Non-catalytic mechanisms involved in glutathione Stransferase Pi mediated cytoprotection

McGarry, D. J., Wolf, C. R. & Henderson, C. J. 18-Dec-2011 In : Toxicology. 290, 2-3, p. 130-130, 1 p.

Research output: Contribution to journal › Book/Film/Article review

Effect of hepatic cytochrome P450 (P450) oxidoreductase deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 reductase conditional null mice

Arlt, V. M., Singh, R., Stiborova, M., da Costa, G. G., Frei, E., Evans, J. D., Farmer, P. B., Wolf, C. R., Henderson, C. J. & Phillips, D. H. Dec-2011 In : Drug Metabolism and Disposition. 39, 12, p. 2169-2173, 5 p.

Research output: Contribution to journal › Article

Increased Skin Papilloma Formation in Mice Lacking Glutathione Transferase GSTP

Henderson, C. J., Ritchie, K. J., McLaren, A., Chakravarty, P. & Wolf, C. R. 15-Nov-2011 In : Cancer Research. 71, 22, p. 7048-7060, 13 p.

Research output: Contribution to journal › Article

Humanizing pi-Class Glutathione S-Transferase Regulation in a Mouse Model Alters Liver Toxicity in Response to Acetaminophen Overdose

Vaughn, M. P., Shinohara, D. B., Castagna, N., Hicks, J. L., Netto, G., De Marzo, A. M., Speed, T. J., Reichert, Z. R., Kwabi-Addo, B., Henderson, C. J., Wolf, C. R., Yegnasubramanian, S. & Nelson, W. G. 11-Oct-2011 In : PLoS ONE. 6, 10, p. -, 10 p., e25707

Research output: Contribution to journal › Article

Enzyme and protein engineering: engineering a self-sufficient human cytochrome P450 monooxygenase system

Deeni, Y. & Wolf, R. Sep-2011 In : Current Opinion in Biotechnology. 22, p. S18-S18, 1 p.

Research output: Contribution to journal › Book/Film/Article review

Quantitative Prediction of Human Pregnane X Receptor and Cytochrome P450 3A4 Mediated Drug-Drug Interaction in a Novel Multiple Humanized Mouse Line

Hasegawa, M., Kapelyukh, Y., Tahara, H., Seibler, J., Rode, A., Krueger, S., Lee, D. N., Wolf, C. R. & Scheer, N. Sep-2011 In : Molecular Pharmacology. 80, 3, p. 518-528, 11 p.

Research output: Contribution to journal › Article

Role of CAR and PXR in xenobiotic toxicity

Wolf, C. R., Elcombe, C., Rode, A., Scheer, N., Bower, C. & Henderson, C. 28-Aug-2011 In : Toxicology Letters. 205, p. S13-S13, 1 p.

Research output: Contribution to journal › Book/Film/Article review

The Imidazoacridinone Antitumor Drug, C-1311, Is Metabolized by Flavin Monooxygenases but Not by Cytochrome P450s

Potega, A., Dabrowska, E., Niemira, M., Kot-Wasik, A., Ronseaux, S., Henderson, C. J., Wolf, C. R. & Mazerska, Z. Aug-2011 In : Drug Metabolism and Disposition. 39, 8, p. 1423-1432, 10 p.

Research output: Contribution to journal › Article