Discovery - University of Dundee - Online Publications

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Roland Wolf

  1. Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer

    MacLeod, A. K., Acosta-Jimenez, L., Coates, P. J., McMahon, M., Carey, F. A., Honda, T., Henderson, C. J. & Wolf, C. R. 6 Dec 2016 In : British Journal of Cancer. 115, 12, p. 1530-1539 10 p.

    Research output: Contribution to journalArticle

  2. Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans

    Takahashi, S., Fukami, T., Masuo, Y., Brocker, C. N., Xie, C., Krausz, K. W., Wolf, C. R., Henderson, C. J. & Gonzalez, F. J. Dec 2016 In : Journal of Lipid Research. 57, p. 2130-2037 8 p.

    Research output: Contribution to journalArticle

  3. Olaparib, monotherapy or with ionizing radiation, exacerbates DNA damage in normal tissues: insights from a new p21 reporter mouse

    McMahon, M., Frangova, T. G., Henderson, C. J. & Wolf, C. R. Dec 2016 In : Molecular Cancer Research. 14, 12, p. 1195-1203 9 p.

    Research output: Contribution to journalArticle

  4. Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

    Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J. 20 Nov 2016 New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January, p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  5. Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π

    McMillan, D. H. , van der Velden, J. L. J. , Lahue, K. G. , Quan, X. , Schneider, R. W. , Iberg, M. S. , Nolin, J. D. , Abdalla, S. , Casey, D. T. , Tew, K. D. , Townsend, D. M. , Henderson, C. J. , Wolf, C. R. , Butnor, K. J. , Taatjes, D. J. , Budd, R. C. , Irvin, C. G. , van der Vliet, A. , Flemer, S. , Anathy, V. & 1 others Janssen-Heininger, Y. M. W. 2 Jun 2016 In : JCI Insight. 1, 8, 16 p., e85717

    Research output: Contribution to journalArticle

  6. Loss of Tet1-associated 5-hydroxymethylcytosine is concomitant with aberrant promoter hypermethylation in liver cancer

    Thomson, J. P., Ottaviano, R., Unterberger, E. B., Lempiäinen, H., Muller, A., Terranova, R., Illingworth, R. S., Webb, S., Kerr, A. R. W., Lyall, M. J., Drake, A. J., Wolf, C. R., Moggs, J. G., Schwarz, M. & Meehan, R. R. 15 May 2016 In : Cancer Research. 76, 10, p. 3097-3108 12 p.

    Research output: Contribution to journalArticle

  7. The role of protein-protein and protein-membrane Interactions on P450 function

    Scott, E. E., Wolf, C. R., Otyepka, M., Humphreys, S. C., Reed, J. R., Henderson, C. J., McLaughlin, L. A., Paloncyova, M., Navratilova, V., Berka, K., Anzenbacher, P., Dahal, U. P., Barnaba, C., Brozik, J. A., Jones, J. P., Estrada, F., Laurence, J. S., Park, J. W. & Backes, W. L. Apr 2016 In : Drug Metabolism and Disposition. 44, 4, p. 576-590 15 p.

    Research output: Contribution to journalArticle

  8. Recurrent Coding Sequence Variation Explains only A Small Fraction of the Genetic Architecture of Colorectal Cancer

    Timofeeva, M. N. , Kinnersley, B. , Farrington, S. M. , Whiffin, N. , Palles, C. , Svinti, V. , Lloyd, A. , Gorman, M. , Ooi, L. Y. , Hosking, F. , Barclay, E. , Zgaga, L. , Dobbins, S. , Martin, L. , Theodoratou, E. , Broderick, P. , Tenesa, A. , Smillie, C. , Grimes, G. , Hayward, C. & 41 others Campbell, A., Porteous, D., Deary, I. J., Harris, S. E., Northwood, E. L., Barrett, J. H., Smith, G., Wolf, R., Forman, D., Morreau, H., Ruano, D., Tops, C., Wijnen, J., Schrumpf, M., Boot, A., Vasen, H. F. A., Hes, F. J., Van Wezel, T., Franke, A., Lieb, W., Schafmayer, C., Hampe, J., Buch, S., Propping, P., Hemminki, K., Försti, A., Westers, H., Hofstra, R., Pinheiro, M., Pinto, C., Teixeira, M., Ruiz-Ponte, C., Fernández-Rozadilla, C., Carracedo, A., Castells, A., Castellví-Bel, S., Campbell, H., Bishop, D. T., Tomlinson, I. P. M., Dunlop, M. G. & Houlston, R. S. 10 Nov 2015 In : Scientific Reports. 5, 10 p., 16286

    Research output: Contribution to journalArticle

  9. Activation status of the Pregnane X Receptor influences Vemurafenib availability in humanized mouse models

    MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R. 1 Nov 2015 In : Cancer Research. 75, 21, p. 4573-4581 10 p.

    Research output: Contribution to journalArticle

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