Roland Wolf

A general strategy for the expression of recombinant human cytochrome P450s in Escherichia coli using bacterial signal peptides: expression of CYP3A4, CYP2A6, and CYP2E1

Pritchard, M. P., Ossetian, R., Li, D. N., Henderson, C. J., Burchell, B., Wolf, C. R. & Friedberg, T. 15-Sep-1997 In : Archives of Biochemistry and Biophysics. 345, 2, p. 342-354, 13 p.

Research output: Contribution to journal › Article

Genetic structural and functional analysis of cytochrome P450s in the CYP2D gene family

Wolf, C. R., Modi, S., Lian, L. Y., Paine, M., Smith, G. & Roberts, G. C. K. 31-Jul-1997 In : FASEB Journal. 11, 9, p. A773-A773, 1 p., P25

Research output: Contribution to journal › Meeting abstract

Active site models of human cytochrome P450s based on NMR relaxation measurements

Modi, S., Paine, M. J., Oliver, C. F., Smith, G., Sutcliffe, M. J., Gilham, D. E., Shaw, A. N. J., Lian, L. Y., Primrose, W. U., Wolf, C. R. & Roberts, G. C. K. 1997 In : FASEB Journal. 11, 9, p. A771-A771, 1 p.

Research output: Contribution to journal › Meeting abstract

Coexpression of a human P450 (CYP3A4) and P450 reductase generates a highly functional monooxygenase system in Escherichia coli

Blake, J. A. R., Pritchard, M., Ding, S., Smith, G. C. M., Burchell, B., Wolf, C. R. & Friedberg, T. 18-Nov-1996 In : FEBS Letters. 397, 2-3, p. 210-214, 5 p.

Research output: Contribution to journal › Article

Transfer of PCBs via lactation simultaneously induces the expression of P450 isoenzymes and the protooncogenes c-Ha-ras and c-raf in neonates

Borlak, J. T., Scott, A., Henderson, C. J., Jenke, H. J. & Wolf, C. R. 23-Feb-1996 In : Biochemical Pharmacology. 51, 4, p. 517-529, 13 p.

Research output: Contribution to journal › Article

Active-site topologies of human CYP2D6 and its aspartate-301 → glutamate, asparagine, and glycine mutants

Mackman, R., Tschirret-Guth, R. A., Smith, G., Hayhurst, G. P., Ellis, S. W., Lennard, M. S., Tucker, G. T., Wolf, C. R. & Ortiz de Montellano, P. R. 1996 In : Archives of Biochemistry and Biophysics. 331, 1, p. 134-140, 7 p.

Research output: Contribution to journal › Article

Genetic analysis of the human cytochrome P450 CYP2C9 locus

Stubbins, M. J., Harries, L. W., Smith, G., Tarbit, M. H. & Wolf, C. R. 1996 In : Pharmacogenetics. 6, 5, p. 429-39, 11 p.

Research output: Contribution to journal › Article

Characterization of anti-LKM-antibody targets in patients with autoimmune hepatitis typ2 and hepatitis-C

Thalhammer, T., Smith, G., Wolf, H., Wolf, R., Boltznitulescu, G., Dopplinger, C. & Penner, E. 9-Mar-1995 In : FASEB Journal. 9, 3, p. A146-A146, 1 p., 851

Research output: Contribution to journal › Meeting abstract

Divergent regulation of cytochrome P450 enzymes by morphine and pethidine: a neuroendocrine mechanism?

Rane, A., Liu, Z., Henderson, C. J. & Wolf, C. R. Jan-1995 In : Molecular Pharmacology. 47, 1, p. 57-64, 8 p.

Research output: Contribution to journal › Article

Evidence that aspartic acid 301 is a critical substrate-contact residue in the active site of cytochrome P450 2D6

Ellis, S. W., Hayhurst, G. P., Smith, G., Lightfoot, T., Wong, M. M. S., Simula, A. P., Ackland, M. J., Sternberg, M. J. E., Lennard, M. S., Tucker, G. T. & Wolf, C. R. 1995 In : Journal of Biological Chemistry. 270, 49, p. 29055-29058, 4 p.

Research output: Contribution to journal › Comment/debate