Discovery - University of Dundee - Online Publications

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Roland Wolf

  1. Determinants of the substrate specificity of human cytochrome P-450 CYP2D6: design and construction of a mutant with testosterone hydroxylase activity

    Smith, G., Modi, S., Pillai, I., Lian, L-Y., Sutcliffe, M. J., Pritchard, M. P., Friedberg, T., Roberts, G. C. K. & Wolf, C. R. 1998 In : Biochemical Journal. 331 , 3, p. 783-792 10 p.

    Research output: Contribution to journalArticle

  2. Molecular genetics of the human cytochrome P450 monooxygenase superfamily

    Smith, G., Stubbins, M. J., Harries, L. W. & Wolf, C. R. 1998 In : Xenobiotica. 28, 12, p. 1129-1165 37 p.

    Research output: Contribution to journalArticle

  3. A general strategy for the expression of recombinant human cytochrome P450s in Escherichia coli using bacterial signal peptides: expression of CYP3A4, CYP2A6, and CYP2E1

    Pritchard, M. P., Ossetian, R., Li, D. N., Henderson, C. J., Burchell, B., Wolf, C. R. & Friedberg, T. 15 Sep 1997 In : Archives of Biochemistry and Biophysics. 345, 2, p. 342-354 13 p.

    Research output: Contribution to journalArticle

  4. Genetic structural and functional analysis of cytochrome P450s in the CYP2D gene family

    Wolf, C. R., Modi, S., Lian, L. Y., Paine, M., Smith, G. & Roberts, G. C. K. 31 Jul 1997 In : FASEB Journal. 11, 9, p. A773-A773 1 p., P25

    Research output: Contribution to journalMeeting abstract

  5. Active site models of human cytochrome P450s based on NMR relaxation measurements

    Modi, S., Paine, M. J., Oliver, C. F., Smith, G., Sutcliffe, M. J., Gilham, D. E., Shaw, A. N. J., Lian, L. Y., Primrose, W. U., Wolf, C. R. & Roberts, G. C. K. 1997 In : FASEB Journal. 11, 9, p. A771-A771 1 p.

    Research output: Contribution to journalMeeting abstract

  6. Coexpression of a human P450 (CYP3A4) and P450 reductase generates a highly functional monooxygenase system in Escherichia coli

    Blake, J. A. R., Pritchard, M., Ding, S., Smith, G. C. M., Burchell, B., Wolf, C. R. & Friedberg, T. 18 Nov 1996 In : FEBS Letters. 397, 2-3, p. 210-214 5 p.

    Research output: Contribution to journalArticle

  7. Transfer of PCBs via lactation simultaneously induces the expression of P450 isoenzymes and the protooncogenes c-Ha-ras and c-raf in neonates

    Borlak, J. T., Scott, A., Henderson, C. J., Jenke, H. J. & Wolf, C. R. 23 Feb 1996 In : Biochemical Pharmacology. 51, 4, p. 517-529 13 p.

    Research output: Contribution to journalArticle

  8. Active-site topologies of human CYP2D6 and its aspartate-301 → glutamate, asparagine, and glycine mutants

    Mackman, R., Tschirret-Guth, R. A., Smith, G., Hayhurst, G. P., Ellis, S. W., Lennard, M. S., Tucker, G. T., Wolf, C. R. & Ortiz de Montellano, P. R. 1996 In : Archives of Biochemistry and Biophysics. 331, 1, p. 134-140 7 p.

    Research output: Contribution to journalArticle

  9. Genetic analysis of the human cytochrome P450 CYP2C9 locus

    Stubbins, M. J., Harries, L. W., Smith, G., Tarbit, M. H. & Wolf, C. R. 1996 In : Pharmacogenetics. 6, 5, p. 429-39 11 p.

    Research output: Contribution to journalArticle

  10. Divergent regulation of cytochrome P450 enzymes by morphine and pethidine: a neuroendocrine mechanism?

    Rane, A., Liu, Z., Henderson, C. J. & Wolf, C. R. Jan 1995 In : Molecular Pharmacology. 47, 1, p. 57-64 8 p.

    Research output: Contribution to journalArticle

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