Roland Wolf

Deletion of Microsomal Cytochrome b(5) Profoundly Affects Hepatic and Extrahepatic Drug Metabolism

McLaughlin, L. A., Ronseaux, S., Finn, R. D., Henderson, C. J. & Wolf, C. R. Aug-2010 In : Molecular Pharmacology. 78, 2, p. 269-278, 10 p.

Research output: Contribution to journal › Article

Human Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) Support the Hypertrophic but not the Hyperplastic Response to the Murine Nongenotoxic Hepatocarcinogens Phenobarbital and Chlordane In Vivo

Ross, J., Plummer, S. M., Rode, A., Scheer, N., Bower, C. C., Vogel, O., Henderson, C. J., Wolf, C. R. & Elcombe, C. R. Aug-2010 In : Toxicological Sciences. 116, 2, p. 452-466, 15 p.

Research output: Contribution to journal › Article

Peroxiredoxin Gene Expression Signatures in Liver Reflect Toxic Insult

Young, R., Hayes, J. D., Brown, K., Wolf, C. R. & Whitelaw, C. B. A. Aug-2010 In : ASSAY and Drug Development Technologies. 8, 4, p. 512-517, 6 p.

Research output: Contribution to journal › Article

In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in Mice

Scheer, N., Ross, J., Kapelyukh, Y., Rode, A. & Wolf, C. R. Jul-2010 In : Drug Metabolism and Disposition. 38, 7, p. 1046-1053, 8 p.

Research output: Contribution to journal › Article

Polymorphisms in xenobiotic metabolizing enzymes and diet influence colorectal adenoma risk

Northwood, E. L., Elliott, F., Forman, D., Barrett, J. H., Wilkie, M. J. V., Carey, F. A., Steele, R. J. C., Wolf, R., Bishop, T. & Smith, G. May-2010 In : Pharmacogenetics and Genomics. 20, 5, p. 315-326, 12 p.

Research output: Contribution to journal › Article

Glutathione S-transferase M1 (GSTM1) genotype is associated with serum 8-MOP concentration and PUVA sensitivity

Ibbotson, S. H., Dawe, R. S., Weidlich, S., Dinkova-Kostova, A. T., Farr, P. M., Ferguson, J., Wolf, C. R. & Smith, G. Apr-2010 In : British Journal of Dermatology. 162, 4, p. 941-941, 1 p.

Research output: Contribution to journal › Meeting abstract

The Hepatic cytochrome P450 reductase null (HRN) mouse model as a tool to study xenobiotic metabolism

Arlt, V. M., Henderson, C. J., Wolf, C. R., Phillips, D. H. & Stiborova, M. Mar-2010 In : Naunyn-Schmiedeberg's Archives of Pharmacology. 381, p. 83-83, 1 p.

Research output: Contribution to journal › Book/Film/Article review

Activating K-Ras mutations outwith 'hotspot' codons in sporadic colorectal tumours: implications for personalised cancer medicine

Smith, G., Bounds, R., Wolf, H., Steele, R., Carey, F. & Wolf, R. 16-Feb-2010 In : British Journal of Cancer. 102, 4, p. 693-703, 11 p.

Research output: Contribution to journal › Article

Activation of the NRF2 Signaling Pathway by Copper-Mediated Redox Cycling of Para- and Ortho-Hydroquinones

Wang, X. J., Hayes, J. D., Higgins, L. G., Wolf', C. R. & Dinkova-Kostova, A. T. 29-Jan-2010 In : Chemistry & Biology. 17, 1, p. 75-85, 11 p.

Research output: Contribution to journal › Article

Markedly enhanced colon tumorigenesis in Apc(Min) mice lacking glutathione S-transferase Pi

Ritchie, K. J., Walsh, S., Sansom, O. J., Henderson, C. J. & Wolf, C. R. 8-Dec-2009 In : Proceedings of the National Academy of Sciences of the United States of America. 106, 49, p. 20859-20864, 6 p.

Research output: Contribution to journal › Article