Discovery - University of Dundee - Online Publications

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Roland Wolf

  1. Xenobiotic CAR activators induce Dlk1-Dio3 locus non-coding RNA expression in mouse liver

    Henderson, C. J. , Wolf, C. R. & 19 others Pouché , L., Vitobello, A., Römer, M., Glogovac, M., MacLeod, A. K., Ellinger-Ziegelbauer, H., Westphal, M., Dubost, V., Stiehl, D. P., Dumotier, B., Fekete, A., Moulin, P., Zell, A., Schwarz, M., Moreno , R., Huang, J. T. J., Elcombe, C. R., Moggs, J. G. & Terranova, R. 25 May 2017 In : Toxicological Sciences.

    Research output: Contribution to journalArticle

  2. Progress in identifying epigenetic mechanisms of xenobiotic-induced non-genotoxic carcinogenesis

    Terranova, R., Vitobello, A., Del Rio Espinola, A., Wolf, C. R., Schwarz, M., Thomson, J. M., Meehan, R. & Moggs, J. G. Apr 2017 In : Current Opinion in Toxicology. 3, p. 62-70 9 p.

    Research output: Contribution to journalReview article

  3. Corrigendum to "Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer"

    MacLeod, A. K., Acosta-Jimenez, L., Coates, P. J., McMahon, M., Carey, F. A., Honda, T., Hayes, J. D., Henderson, C. J. & Wolf, C. R. 21 Mar 2017 In : British Journal of Cancer. 1 p.

    Research output: Contribution to journalArticle

  4. Feedback control of AHR signalling regulates intestinal immunity

    Schiering, C., Wincent, E., Metidji, A., Iseppon, A., Li, Y., Potocnik, A. J., Omenetti, S., Henderson, C. J., Wolf, C. R., Nebert, D. W. & Stockinger, B. 9 Feb 2017 In : Nature. 542, 7640, p. 242-245 4 p.

    Research output: Contribution to journalLetter

  5. Aryl hydrocarbon receptor is required for optimal B-cell proliferation

    Villa, M., Gialitakis, M., Tolaini, M., Ahlfors, H., Henderson, C. J., Wolf, C. R., Brink, R. & Stockinger, B. 4 Jan 2017 In : EMBO Journal. 36, 1, p. 116-128 13 p.

    Research output: Contribution to journalArticle

  6. Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer

    MacLeod, A. K., Acosta-Jimenez, L., Coates, P. J., McMahon, M., Carey, F. A., Honda, T., Henderson, C. J. & Wolf, C. R. 6 Dec 2016 In : British Journal of Cancer. 115, 12, p. 1530-1539 10 p.

    Research output: Contribution to journalArticle

  7. Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans

    Takahashi, S., Fukami, T., Masuo, Y., Brocker, C. N., Xie, C., Krausz, K. W., Wolf, C. R., Henderson, C. J. & Gonzalez, F. J. Dec 2016 In : Journal of Lipid Research. 57, p. 2130-2037 8 p.

    Research output: Contribution to journalArticle

  8. Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

    Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J. 20 Nov 2016 New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January, p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  9. Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π

    Henderson, C. J. , Wolf, C. R. & 19 others McMillan, D. H., van der Velden, J. L. J., Lahue, K. G., Quan, X., Schneider, R. W., Iberg, M. S., Nolin, J. D., Abdalla, S., Casey, D. T., Tew, K. D., Townsend, D. M., Butnor, K. J., Taatjes, D. J., Budd, R. C., Irvin, C. G., van der Vliet, A., Flemer, S., Anathy, V. & Janssen-Heininger, Y. M. W. 2 Jun 2016 In : JCI Insight. 1, 8, 16 p., e85717

    Research output: Contribution to journalArticle

  10. Loss of Tet1-associated 5-hydroxymethylcytosine is concomitant with aberrant promoter hypermethylation in liver cancer

    Thomson, J. P., Ottaviano, R., Unterberger, E. B., Lempiäinen, H., Muller, A., Terranova, R., Illingworth, R. S., Webb, S., Kerr, A. R. W., Lyall, M. J., Drake, A. J., Wolf, C. R., Moggs, J. G., Schwarz, M. & Meehan, R. R. 15 May 2016 In : Cancer Research. 76, 10, p. 3097-3108 12 p.

    Research output: Contribution to journalArticle

  11. The role of protein-protein and protein-membrane Interactions on P450 function

    Scott, E. E., Wolf, C. R., Otyepka, M., Humphreys, S. C., Reed, J. R., Henderson, C. J., McLaughlin, L. A., Paloncyova, M., Navratilova, V., Berka, K., Anzenbacher, P., Dahal, U. P., Barnaba, C., Brozik, J. A., Jones, J. P., Estrada, F., Laurence, J. S., Park, J. W. & Backes, W. L. Apr 2016 In : Drug Metabolism and Disposition. 44, 4, p. 576-590 15 p.

    Research output: Contribution to journalArticle

  12. Recurrent Coding Sequence Variation Explains only A Small Fraction of the Genetic Architecture of Colorectal Cancer

    Smith, G. , Wolf, R. & 59 others Timofeeva, M. N., Kinnersley, B., Farrington, S. M., Whiffin, N., Palles, C., Svinti, V., Lloyd, A., Gorman, M., Ooi, L. Y., Hosking, F., Barclay, E., Zgaga, L., Dobbins, S., Martin, L., Theodoratou, E., Broderick, P., Tenesa, A., Smillie, C., Grimes, G., Hayward, C., Campbell, A., Porteous, D., Deary, I. J., Harris, S. E., Northwood, E. L., Barrett, J. H., Forman, D., Morreau, H., Ruano, D., Tops, C., Wijnen, J., Schrumpf, M., Boot, A., Vasen, H. F. A., Hes, F. J., Van Wezel, T., Franke, A., Lieb, W., Schafmayer, C., Hampe, J., Buch, S., Propping, P., Hemminki, K., Försti, A., Westers, H., Hofstra, R., Pinheiro, M., Pinto, C., Teixeira, M., Ruiz-Ponte, C., Fernández-Rozadilla, C., Carracedo, A., Castells, A., Castellví-Bel, S., Campbell, H., Bishop, D. T., Tomlinson, I. P. M., Dunlop, M. G. & Houlston, R. S. 10 Nov 2015 In : Scientific Reports. 5, 10 p., 16286

    Research output: Contribution to journalArticle

  13. Activation status of the Pregnane X Receptor influences Vemurafenib availability in humanized mouse models

    MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R. 1 Nov 2015 In : Cancer Research. 75, 21, p. 4573-4581 10 p.

    Research output: Contribution to journalArticle

  14. Defining human pathways of drug metabolism in vivo through the development of a multiple humanized mouse model

    Scheer, N., Kapelyukh, Y., Rode, A., Oswald, S., Busch, D., McLaughlin, L. A., Lin, D., Henderson, C. J. & Wolf, C. R. Nov 2015 In : Drug Metabolism and Disposition. 43, 11, p. 1679-1690 12 p.

    Research output: Contribution to journalArticle

  15. Model systems for understanding mechanisms of non-genotoxic carcinogenesis: response

    Braeuning, A., Henderson, C. J., Wolf, C. R. & Schwarz, M. Oct 2015 In : Toxicological Sciences. 147, 2, p. 299-300 2 p.

    Research output: Contribution to journalLetter

  16. Proteome-wide identification and quantification of S-glutathionylation targets in mouse liver

    McGarry, D. J., Chen, W., Chakravarty, P., Lamont, D. L., Wolf, C. R. & Henderson, C. J. Jun 2015 In : Biochemical Journal. 469, 1, p. 25-32 8 p.

    Research output: Contribution to journalArticle

  17. Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability

    Henderson, C. J., Cameron, A. R., Chatham, L., Stanley, L. A. & Wolf, C. R. May 2015 In : Toxicological Sciences. 145, 1, p. 138-148 11 p.

    Research output: Contribution to journalArticle

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