Discovery - University of Dundee - Online Publications

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Roland Wolf

  1. Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk: A case-control study in unselected white European populations

    Sheth, H. , Northwood, E. , Ulrich, C. M. , Scherer, D. , Elliott, F. , Barrett, J. H. , Forman, D. , Wolf, C. R. , Smith, G. , Jackson, M. S. , Santibanez-Koref, M. , Haile, R. , Casey, G. , Jenkins, M. , Win, A. K. , Hopper, J. L. , Marchand, L. L. , Lindor, N. M. , Thibodeau, S. N. , Potter, J. D. & 2 others Burn, J. & Bishop, D. T. 9 Feb 2018 In : PLoS ONE. 13, 2, p. 1-17 17 p., e0192223

    Research output: Contribution to journalArticle

  2. Identification of novel pathways of osimertinib disposition and potential implications for the outcome of lung cancer therapy

    MacLeod, A. K., Lin, D., Huang, J. T-J., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R. 6 Feb 2018 In : Clinical Cancer Research.

    Research output: Contribution to journalArticle

  3. Cytochrome b5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b5 /P450 reductase null (HBRN) mice

    Reed, L., Mrizova, I., Barta, F., Indra, R., Moserova, M., Kopka, K., Schmeiser, H. H., Wolf, C. R., Henderson, C. J., Stiborova, M., Phillips, D. H. & Arlt, V. M. 24 Jan 2018 In : Archives of Toxicology. 14 p.

    Research output: Contribution to journalArticle

  4. Measuring in vivo responses to endogenous and exogenous oxidative stress using a novel Heme Oxygenase 1 reporter mouse

    McMahon, M., Ding, S., Acosta-Jimenez, L. P., Frangova, T. G., Henderson, C. J. & Wolf, C. R. 1 Jan 2018 In : Journal of Physiology. 596, 1, p. 105-127 23 p.

    Research output: Contribution to journalArticle

  5. Corrigendum to "Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer"

    MacLeod, A. K., Acosta-Jimenez, L., Coates, P. J., McMahon, M., Carey, F. A., Honda, T., Hayes, J. D., Henderson, C. J. & Wolf, C. R. 22 Aug 2017 In : British Journal of Cancer. 117, 1 p., e1

    Research output: Contribution to journalArticle

  6. Xenobiotic CAR activators induce Dlk1-Dio3 locus non-coding RNA expression in mouse liver

    Pouché , L. , Vitobello, A. , Römer, M. , Glogovac, M. , MacLeod, A. K. , Ellinger-Ziegelbauer, H. , Westphal, M. , Dubost, V. , Stiehl, D. P. , Dumotier, B. , Fekete, A. , Moulin, P. , Zell, A. , Schwarz, M. , Moreno , R. , Huang, J. T. J. , Elcombe, C. R. , Henderson, C. J. , Wolf, C. R. , Moggs, J. G. & 1 others Terranova, R. Aug 2017 In : Toxicological Sciences. 158, 2, p. 367-378 11 p.

    Research output: Contribution to journalArticle

  7. Progress in identifying epigenetic mechanisms of xenobiotic-induced non-genotoxic carcinogenesis

    Terranova, R., Vitobello, A., Del Rio Espinola, A., Wolf, C. R., Schwarz, M., Thomson, J. M., Meehan, R. & Moggs, J. G. Apr 2017 In : Current Opinion in Toxicology. 3, p. 62-70 9 p.

    Research output: Contribution to journalReview article

  8. Feedback control of AHR signalling regulates intestinal immunity

    Schiering, C., Wincent, E., Metidji, A., Iseppon, A., Li, Y., Potocnik, A. J., Omenetti, S., Henderson, C. J., Wolf, C. R., Nebert, D. W. & Stockinger, B. 9 Feb 2017 In : Nature. 542, 7640, p. 242-245 4 p.

    Research output: Contribution to journalLetter

  9. Aryl hydrocarbon receptor is required for optimal B-cell proliferation

    Villa, M., Gialitakis, M., Tolaini, M., Ahlfors, H., Henderson, C. J., Wolf, C. R., Brink, R. & Stockinger, B. 4 Jan 2017 In : EMBO Journal. 36, 1, p. 116-128 13 p.

    Research output: Contribution to journalArticle

  10. Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer

    MacLeod, A. K., Acosta-Jimenez, L., Coates, P. J., McMahon, M., Carey, F. A., Honda, T., Henderson, C. J. & Wolf, C. R. 6 Dec 2016 In : British Journal of Cancer. 115, 12, p. 1530-1539 10 p.

    Research output: Contribution to journalArticle

  11. Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans

    Takahashi, S., Fukami, T., Masuo, Y., Brocker, C. N., Xie, C., Krausz, K. W., Wolf, C. R., Henderson, C. J. & Gonzalez, F. J. Dec 2016 In : Journal of Lipid Research. 57, p. 2130-2037 8 p.

    Research output: Contribution to journalArticle

  12. Olaparib, monotherapy or with ionizing radiation, exacerbates DNA damage in normal tissues: insights from a new p21 reporter mouse

    McMahon, M., Frangova, T. G., Henderson, C. J. & Wolf, C. R. Dec 2016 In : Molecular Cancer Research. 14, 12, p. 1195-1203 9 p.

    Research output: Contribution to journalArticle

  13. Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

    Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J. 20 Nov 2016 New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January, p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  14. Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π

    McMillan, D. H. , van der Velden, J. L. J. , Lahue, K. G. , Quan, X. , Schneider, R. W. , Iberg, M. S. , Nolin, J. D. , Abdalla, S. , Casey, D. T. , Tew, K. D. , Townsend, D. M. , Henderson, C. J. , Wolf, C. R. , Butnor, K. J. , Taatjes, D. J. , Budd, R. C. , Irvin, C. G. , van der Vliet, A. , Flemer, S. , Anathy, V. & 1 others Janssen-Heininger, Y. M. W. 2 Jun 2016 In : JCI Insight. 1, 8, 16 p., e85717

    Research output: Contribution to journalArticle

  15. Loss of Tet1-associated 5-hydroxymethylcytosine is concomitant with aberrant promoter hypermethylation in liver cancer

    Thomson, J. P., Ottaviano, R., Unterberger, E. B., Lempiäinen, H., Muller, A., Terranova, R., Illingworth, R. S., Webb, S., Kerr, A. R. W., Lyall, M. J., Drake, A. J., Wolf, C. R., Moggs, J. G., Schwarz, M. & Meehan, R. R. 15 May 2016 In : Cancer Research. 76, 10, p. 3097-3108 12 p.

    Research output: Contribution to journalArticle

  16. The role of protein-protein and protein-membrane Interactions on P450 function

    Scott, E. E., Wolf, C. R., Otyepka, M., Humphreys, S. C., Reed, J. R., Henderson, C. J., McLaughlin, L. A., Paloncyova, M., Navratilova, V., Berka, K., Anzenbacher, P., Dahal, U. P., Barnaba, C., Brozik, J. A., Jones, J. P., Estrada, F., Laurence, J. S., Park, J. W. & Backes, W. L. Apr 2016 In : Drug Metabolism and Disposition. 44, 4, p. 576-590 15 p.

    Research output: Contribution to journalArticle

  17. Recurrent Coding Sequence Variation Explains only A Small Fraction of the Genetic Architecture of Colorectal Cancer

    Timofeeva, M. N. , Kinnersley, B. , Farrington, S. M. , Whiffin, N. , Palles, C. , Svinti, V. , Lloyd, A. , Gorman, M. , Ooi, L. Y. , Hosking, F. , Barclay, E. , Zgaga, L. , Dobbins, S. , Martin, L. , Theodoratou, E. , Broderick, P. , Tenesa, A. , Smillie, C. , Grimes, G. , Hayward, C. & 41 others Campbell, A., Porteous, D., Deary, I. J., Harris, S. E., Northwood, E. L., Barrett, J. H., Smith, G., Wolf, R., Forman, D., Morreau, H., Ruano, D., Tops, C., Wijnen, J., Schrumpf, M., Boot, A., Vasen, H. F. A., Hes, F. J., Van Wezel, T., Franke, A., Lieb, W., Schafmayer, C., Hampe, J., Buch, S., Propping, P., Hemminki, K., Försti, A., Westers, H., Hofstra, R., Pinheiro, M., Pinto, C., Teixeira, M., Ruiz-Ponte, C., Fernández-Rozadilla, C., Carracedo, A., Castells, A., Castellví-Bel, S., Campbell, H., Bishop, D. T., Tomlinson, I. P. M., Dunlop, M. G. & Houlston, R. S. 10 Nov 2015 In : Scientific Reports. 5, 10 p., 16286

    Research output: Contribution to journalArticle

  18. Activation status of the Pregnane X Receptor influences Vemurafenib availability in humanized mouse models

    MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R. 1 Nov 2015 In : Cancer Research. 75, 21, p. 4573-4581 10 p.

    Research output: Contribution to journalArticle

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