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Roland Wolf

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  1. A role for cytochrome b5 in the in vivo disposition of anti-cancer and cytochrome P450 probe drugs in mice

    Henderson, C. J., McLaughlin, L. A., Finn, R. D., Ronseaux, S., Kapelyukh, Y. & Wolf, C. R. Jan 2014 In : Drug Metabolism and Disposition. 42, 1, p. 70-77 8 p.

    Research output: Contribution to journalArticle

  2. Cytochrome P450 CYP1B1 interacts with 8-methoxypsoralen (8-MOP) and influences psoralen-ultraviolet (PUVA) sensitivity

    Deeni, Y. Y., Ibbotson, S. H., Woods, J. A., Wolf, C. R. & Smith, G. 23 Sep 2013 In : PLoS ONE. 8, 9, e75494

    Research output: Contribution to journalArticle

  3. Ubiquitin-proteasome system impairment and MPTP-induced oxidative stress in the brain of C57BL/6 wild-type and GSTP knockout mice

    Carvalho, A. N., Marques, C., Rodrigues, E., Henderson, C. J., Wolf, C. R., Pereira, P. & Gama, M. J. Apr 2013 In : Molecular Neurobiology. 47, 2, p. 662-72 11 p.

    Research output: Contribution to journalArticle

  4. NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology

    Riddick, D. S., Ding, X., Wolf, C. R., Porter, T. D., Pandey, A. V., Zhang, Q-Y., Gu, J., Finn, R. D., Ronseaux, S., McLaughlin, L. A., Henderson, C. J., Zou, L. & Flück, C. E. Jan 2013 In : Drug Metabolism and Disposition. 41, 1, p. 12-23 12 p.

    Research output: Contribution to journalArticle

  5. The involvement of mitochondrial amidoxime reducing components 1 and 2 and mitochondrial cytochrome b5 in N-reductive metabolism in human cells

    Plitzko, B., Ott, G., Reichmann, D., Henderson, C. J., Wolf, C. R., Mendel, R., Bittner, F., Clement, B. & Havemeyer, A. 2013 In : Journal of Biological Chemistry. 288, 28, p. 20228-20237 10 p.

    Research output: Contribution to journalArticle

  6. Individuality in FGF1 expression significantly influences platinum resistance and progression-free survival in ovarian cancer

    Smith, G., Ng, M. T. H., Shepherd, L., Herrington, C. S., Gourley, C., Ferguson, M. & Wolf, C. R. 9 Oct 2012 In : British Journal of Cancer. 107, 8, p. 1327-1336 10 p.

    Research output: Contribution to journalArticle

  7. Characterization of a Human Keratinocyte HaCaT Cell Line Model to Study the Regulation of CYP2S1

    McNeilly, A. D., Woods, J. A., Ibbotson, S. H., Wolf, C. R. & Smith, G. Feb 2012 In : Drug Metabolism and Disposition. 40, 2, p. 283-289 7 p.

    Research output: Contribution to journalArticle

  8. Glutathione S-transferase genotype is associated with sensitivity to psoralen-ultraviolet A photochemotherapy

    Ibbotson, S. H., Dawe, R. S., Dinkova-Kostova, A. T., Weidlich, S., Farr, P. M., Ferguson, J., Wolf, C. R. & Smith, G. Feb 2012 In : British Journal of Dermatology. 166, 2, p. 380-388 9 p.

    Research output: Contribution to journalArticle

  9. The role of bioreductive activation of antitumour anthracycline drugs in cytotoxic activity against sensitive and multidrug resistant leukaemia HL60 cells

    Kostrzewa-Nowak, D., Bieg, B., Paine, M. J. I., Wolf, C. R. & Tarasiuk, J. 14 Jan 2012 In : European Journal of Pharmacology. 674, 2-3, p. 112-125 14 p.

    Research output: Contribution to journalArticle

  10. Glutathione S-Transferase pi Mediates MPTP-Induced c-Jun N-Terminal Kinase Activation in the Nigrostriatal Pathway

    Castro-Caldas, M., Carvalho, A. N., Rodrigues, E., Gama, M. J., Henderson, C. & Wolf, C. R. 1 Jan 2012 In : Molecular Neurobiology. p. 1-12 12 p.

    Research output: Contribution to journalArticle

  11. Modeling Human Cytochrome P450 2D6 Metabolism and Drug-Drug Interaction by a Novel Panel of Knockout and Humanized Mouse Lines

    Scheer, N., Kapelyukh, Y., McEwan, J., Beuger, V., Stanley, L. A., Rode, A. & Wolf, C. R. Jan 2012 In : Molecular Pharmacology. 81, 1, p. 63-72 10 p.

    Research output: Contribution to journalArticle

  12. Conditional expression of human PPARδ and a dominant negative variant of hPPARδ in vivo

    Higgins, L. G., Garbacz, W. G., Gustafsson, M. C. U., Sitheswaran, N., Ashby, P. R., Wolf, C. R. & Palmer, C. N. A. 2012 In : PPAR Research. 12 p.216817

    Research output: Contribution to journalArticle

  13. Exposure to benzo[a]pyrene of hepatic cytochrome P450 reductase null (HRN) and P450 reductase conditional null (RCN) mice: detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and P-postlabelling

    Arlt, V. M., Poirier, M. C., Sykes, S. E., John, K., Moserova, M., Stiborova, M., Wolf, C. R., Henderson, C. J. & Phillips, D. H. 2012 In : Toxicology Letters. 213, 2, p. 160-166 7 p.

    Research output: Contribution to journalArticle

  14. Generation and characterization of a novel multidrug resistance protein 2 humanized mouse line

    Scheer, N., Balimane, P., Hayward, M. D., Buechel, S., Kauselmann, G. & Wolf, C. R. 2012 In : Drug Metabolism and Disposition. 40, 11, p. 2212-2218 7 p.

    Research output: Contribution to journalArticle

  15. Tauroursodeoxycholic acid prevents MPTP-induced dopaminergic cell death in a mouse model of Parkinson's disease

    Castro-Caldas, M., Carvalho, A. N., Rodrigues, E., Henderson, C. J., Wolf, C. R., Rodrigues, C. M. P. & Gama, M. J. 2012 In : Molecular Neurobiology. 46, 2, p. 475-486 12 p.

    Research output: Contribution to journalArticle

  16. Non-catalytic mechanisms involved in glutathione Stransferase Pi mediated cytoprotection

    McGarry, D. J., Wolf, C. R. & Henderson, C. J. 18 Dec 2011 In : Toxicology. 290, 2-3, p. 130-130 1 p.

    Research output: Contribution to journalBook/Film/Article review

  17. Effect of hepatic cytochrome P450 (P450) oxidoreductase deficiency on 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA Adduct Formation in P450 reductase conditional null mice

    Arlt, V. M., Singh, R., Stiborova, M., da Costa, G. G., Frei, E., Evans, J. D., Farmer, P. B., Wolf, C. R., Henderson, C. J. & Phillips, D. H. Dec 2011 In : Drug Metabolism and Disposition. 39, 12, p. 2169-2173 5 p.

    Research output: Contribution to journalArticle

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