A novel protein transport system involved in the biogenesis of bacterial electron transfer chains. / Berks, Ben C.; Sargent, Frank; De Leeuw, Erik; Hinsley, Andrew P.; Stanley, Nicola R.; Jack, Rachael L.; Buchanan, Grant; Palmer, Tracy.
In: Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1459, No. 2-3, 2000, p. 325-30.Research output: Contribution to journal › Article
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TY - JOUR
T1 - A novel protein transport system involved in the biogenesis of bacterial electron transfer chains
A1 - Berks,Ben C.
A1 - Sargent,Frank
A1 - De Leeuw,Erik
A1 - Hinsley,Andrew P.
A1 - Stanley,Nicola R.
A1 - Jack,Rachael L.
A1 - Buchanan,Grant
A1 - Palmer,Tracy
AU - Berks,Ben C.
AU - Sargent,Frank
AU - De Leeuw,Erik
AU - Hinsley,Andrew P.
AU - Stanley,Nicola R.
AU - Jack,Rachael L.
AU - Buchanan,Grant
AU - Palmer,Tracy
PY - 2000
Y1 - 2000
N2 - The Tat system is a recently discovered bacterial protein transport pathway that functions primarily in the biosynthesis of proteins containing redox active cofactors. Analogous transport systems are found in plant organelles. Remarkably and uniquely the Tat system functions to transported a diverse range of folded proteins across a biological membrane, a feat that must be achieved without rendering the membrane freely permeable to protons and other ions. Here we review the operation of the bacterial Tat system and propose a model for the structural organisation of the Tat preprotein translocase.
AB - The Tat system is a recently discovered bacterial protein transport pathway that functions primarily in the biosynthesis of proteins containing redox active cofactors. Analogous transport systems are found in plant organelles. Remarkably and uniquely the Tat system functions to transported a diverse range of folded proteins across a biological membrane, a feat that must be achieved without rendering the membrane freely permeable to protons and other ions. Here we review the operation of the bacterial Tat system and propose a model for the structural organisation of the Tat preprotein translocase.
U2 - 10.1016/S0005-2728(00)00168-7
DO - 10.1016/S0005-2728(00)00168-7
M1 - Article
JO - Biochimica et Biophysica Acta (BBA) - Bioenergetics
JF - Biochimica et Biophysica Acta (BBA) - Bioenergetics
SN - 0005-2728
IS - 2-3
VL - 1459
SP - 325
EP - 330
ER -