Discovery - University of Dundee - Online Publications

Library & Learning Centre

A randomised controlled trial testing the feasibility and efficacy of a physical activity behavioural change intervention in managing fatigue with gynaecological cancer survivors

Standard

A randomised controlled trial testing the feasibility and efficacy of a physical activity behavioural change intervention in managing fatigue with gynaecological cancer survivors. / Donnelly, C.M.; Blaney, J.M.; Lowe-Strong, A.; McCrum-Gardner, E.; Gracey, J.H.; Rankin, J.P.; Campbell, A.

In: Gynecologic Oncology, Vol. 122, No. 3, 01.09.2011, p. 618-624.

Research output: Contribution to journalArticle

Harvard

Donnelly, CM, Blaney, JM, Lowe-Strong, A, McCrum-Gardner, E, Gracey, JH, Rankin, JP & Campbell, A 2011, 'A randomised controlled trial testing the feasibility and efficacy of a physical activity behavioural change intervention in managing fatigue with gynaecological cancer survivors' Gynecologic Oncology, vol 122, no. 3, pp. 618-624.

APA

Donnelly, C. M., Blaney, J. M., Lowe-Strong, A., McCrum-Gardner, E., Gracey, J. H., Rankin, J. P., & Campbell, A. (2011). A randomised controlled trial testing the feasibility and efficacy of a physical activity behavioural change intervention in managing fatigue with gynaecological cancer survivors. Gynecologic Oncology, 122(3), 618-624doi: 10.1016/j.ygyno.2011.05.029

Vancouver

Donnelly CM, Blaney JM, Lowe-Strong A, McCrum-Gardner E, Gracey JH, Rankin JP et al. A randomised controlled trial testing the feasibility and efficacy of a physical activity behavioural change intervention in managing fatigue with gynaecological cancer survivors. Gynecologic Oncology. 2011 Sep 1;122(3):618-624.

Author

Donnelly, C.M.; Blaney, J.M.; Lowe-Strong, A.; McCrum-Gardner, E.; Gracey, J.H.; Rankin, J.P.; Campbell, A. / A randomised controlled trial testing the feasibility and efficacy of a physical activity behavioural change intervention in managing fatigue with gynaecological cancer survivors.

In: Gynecologic Oncology, Vol. 122, No. 3, 01.09.2011, p. 618-624.

Research output: Contribution to journalArticle

Bibtex - Download

@article{b5ccb4ad785643a49a3bef7bf233acbe,
title = "A randomised controlled trial testing the feasibility and efficacy of a physical activity behavioural change intervention in managing fatigue with gynaecological cancer survivors",
author = "C.M. Donnelly and J.M. Blaney and A. Lowe-Strong and E. McCrum-Gardner and J.H. Gracey and J.P. Rankin and A. Campbell",
year = "2011",
volume = "122",
number = "3",
pages = "618--624",
journal = "Gynecologic Oncology",
issn = "0090-8258",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - A randomised controlled trial testing the feasibility and efficacy of a physical activity behavioural change intervention in managing fatigue with gynaecological cancer survivors

A1 - Donnelly,C.M.

A1 - Blaney,J.M.

A1 - Lowe-Strong,A.

A1 - McCrum-Gardner,E.

A1 - Gracey,J.H.

A1 - Rankin,J.P.

A1 - Campbell,A.

AU - Donnelly,C.M.

AU - Blaney,J.M.

AU - Lowe-Strong,A.

AU - McCrum-Gardner,E.

AU - Gracey,J.H.

AU - Rankin,J.P.

AU - Campbell,A.

PY - 2011/9/1

Y1 - 2011/9/1

N2 - Objective: To determine the feasibility and efficacy of a physical activity behavioural change intervention in managing cancer-related fatigue among gynaecological cancer survivors during and post anti-cancer treatments. Methods: A two arm, single blind, randomised controlled trial was conducted within the Northern Ireland regional Cancer Centre. Thirty three sedentary gynaecological cancer survivors (stage I-III; = 3 years post diagnosis), experiencing cancer-related fatigue (mild-severe) took part. Participants were randomly assigned to a behavioural change, moderate intensity physical activity intervention (n = 16) or a Contact Control group (n = 17). The primary outcome was fatigue (Multidimensional Fatigue Symptom Inventory-Short Form and Functional Assessment in Chronic Illness Therapy-Fatigue subscale). Secondary outcomes included quality of life, physical functioning, positive and negative affect, depression, body composition, sleep dysfunction and self-reported physical activity. Feasibility was assessed based on the recruitment rate, programme and physical activity adherence and participants' programme evaluation, including optional focus groups (n = 16). Results: Twenty five percent of eligible women took part (33/134). Participants were 8.7 (SD = 9.1) months post diagnosis, with a mean age of 53 (SD = 10.3) years. The majority of the sample had a diagnosis of ovarian (n = 12) or endometrial cancer (n = 11). Significant differences favouring the intervention group were observed for fatigue at 12 weeks and 6 months follow-up (12 week: mean difference = -11.06; 95% confidence interval (CI) = -21.89 to - 0.23; effect size (d) = 0.13; p = 0.046; 6 month: mean difference = -19.48; 95% CI = - 19.67 to - 19.15; effect size (d) = 0.20; p = 0.01). A mean of 10 calls (SD = 1.2 calls) were delivered to the Physical Activity Group, and 10 (SD = 1.6 calls) to the CC group. The intervention was positively perceived based on exit questionnaire and focus group findings. Conclusions: A physical activity behavioural change intervention for gynaecological cancer survivors is feasible in terms of participants' programme adherence and evaluation, and the intervention demonstrates improvements in fatigue. However, confirmation in the form of a larger fully powered RCT is warranted. © 2011 Elsevier Inc.

AB - Objective: To determine the feasibility and efficacy of a physical activity behavioural change intervention in managing cancer-related fatigue among gynaecological cancer survivors during and post anti-cancer treatments. Methods: A two arm, single blind, randomised controlled trial was conducted within the Northern Ireland regional Cancer Centre. Thirty three sedentary gynaecological cancer survivors (stage I-III; = 3 years post diagnosis), experiencing cancer-related fatigue (mild-severe) took part. Participants were randomly assigned to a behavioural change, moderate intensity physical activity intervention (n = 16) or a Contact Control group (n = 17). The primary outcome was fatigue (Multidimensional Fatigue Symptom Inventory-Short Form and Functional Assessment in Chronic Illness Therapy-Fatigue subscale). Secondary outcomes included quality of life, physical functioning, positive and negative affect, depression, body composition, sleep dysfunction and self-reported physical activity. Feasibility was assessed based on the recruitment rate, programme and physical activity adherence and participants' programme evaluation, including optional focus groups (n = 16). Results: Twenty five percent of eligible women took part (33/134). Participants were 8.7 (SD = 9.1) months post diagnosis, with a mean age of 53 (SD = 10.3) years. The majority of the sample had a diagnosis of ovarian (n = 12) or endometrial cancer (n = 11). Significant differences favouring the intervention group were observed for fatigue at 12 weeks and 6 months follow-up (12 week: mean difference = -11.06; 95% confidence interval (CI) = -21.89 to - 0.23; effect size (d) = 0.13; p = 0.046; 6 month: mean difference = -19.48; 95% CI = - 19.67 to - 19.15; effect size (d) = 0.20; p = 0.01). A mean of 10 calls (SD = 1.2 calls) were delivered to the Physical Activity Group, and 10 (SD = 1.6 calls) to the CC group. The intervention was positively perceived based on exit questionnaire and focus group findings. Conclusions: A physical activity behavioural change intervention for gynaecological cancer survivors is feasible in terms of participants' programme adherence and evaluation, and the intervention demonstrates improvements in fatigue. However, confirmation in the form of a larger fully powered RCT is warranted. © 2011 Elsevier Inc.

U2 - 10.1016/j.ygyno.2011.05.029

DO - 10.1016/j.ygyno.2011.05.029

M1 - Article

JO - Gynecologic Oncology

JF - Gynecologic Oncology

SN - 0090-8258

IS - 3

VL - 122

SP - 618

EP - 624

ER -

Documents

Library & Learning Centre

Contact | Accessibility | Policy