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Alzheimer's disease risk factor complement receptor 1 is associated with depression

Alzheimer's disease risk factor complement receptor 1 is associated with depression

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Original languageEnglish
Pages6-9
Number of pages4
JournalNeuroscience Letters
Journal publication date2012
Volume510
Issue1
DOIs
StatePublished

Abstract

Variation in the complement receptor 1 gene (CR1) has been identified in recent genome-wide association studies as a risk factor for Alzheimer's disease. Here, we show that two Alzheimer's disease-associated CR1 variants, rs6656401 and rs3818361, are associated with major recurrent depression in females in a population-based cohort using individuals from the Generation Scotland: Scottish Family Health Study. (C) 2012 Elsevier Ireland Ltd. All rights reserved.

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