TY - JOUR T1 - Alzheimer's disease risk factor complement receptor 1 is associated with depression A1 - Hamilton,Gillian A1 - Evans,Kathryn L. A1 - MacIntyre,Donald J. A1 - Deary,Ian J. A1 - Dominiczak,Anna A1 - Smith,Blair H. A1 - Morris,Andrew D. A1 - Porteous,David J. A1 - Thomson,Pippa A. AU - Hamilton,Gillian AU - Evans,Kathryn L. AU - MacIntyre,Donald J. AU - Deary,Ian J. AU - Dominiczak,Anna AU - Smith,Blair H. AU - Morris,Andrew D. AU - Porteous,David J. AU - Thomson,Pippa A. PY - 2012 Y1 - 2012 N2 -

Variation in the complement receptor 1 gene (CR1) has been identified in recent genome-wide association studies as a risk factor for Alzheimer's disease. Here, we show that two Alzheimer's disease-associated CR1 variants, rs6656401 and rs3818361, are associated with major recurrent depression in females in a population-based cohort using individuals from the Generation Scotland: Scottish Family Health Study. (C) 2012 Elsevier Ireland Ltd. All rights reserved.

AB -

Variation in the complement receptor 1 gene (CR1) has been identified in recent genome-wide association studies as a risk factor for Alzheimer's disease. Here, we show that two Alzheimer's disease-associated CR1 variants, rs6656401 and rs3818361, are associated with major recurrent depression in females in a population-based cohort using individuals from the Generation Scotland: Scottish Family Health Study. (C) 2012 Elsevier Ireland Ltd. All rights reserved.

UR - http://www.scopus.com/inward/record.url?partnerID=yv4JPVwI&eid=2-s2.0-84856552809&md5=5d20df4c914c2071a663aa7a5ffaddf5 U2 - 10.1016/j.neulet.2011.12.059 DO - 10.1016/j.neulet.2011.12.059 M1 - Article JO - Neuroscience Letters JF - Neuroscience Letters SN - 0304-3940 IS - 1 VL - 510 SP - 6 EP - 9 ER -