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AMPK and autophagy get connected

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AMPK and autophagy get connected. / Hardie, D. Grahame.

In: EMBO Journal, Vol. 30, No. 4, 16.02.2011, p. 634-635.

Research output: Contribution to journalEditorial

Harvard

Hardie, DG 2011, 'AMPK and autophagy get connected' EMBO Journal, vol 30, no. 4, pp. 634-635.

APA

Hardie, D. G. (2011). AMPK and autophagy get connected. EMBO Journal, 30(4), 634-635doi: 10.1038/emboj.2011.12

Vancouver

Hardie DG. AMPK and autophagy get connected. EMBO Journal. 2011 Feb 16;30(4):634-635.

Author

Hardie, D. Grahame / AMPK and autophagy get connected.

In: EMBO Journal, Vol. 30, No. 4, 16.02.2011, p. 634-635.

Research output: Contribution to journalEditorial

Bibtex - Download

@article{c25b9c98b60b42f6a3d2c7902b47ed29,
title = "AMPK and autophagy get connected",
author = "Hardie, {D. Grahame}",
year = "2011",
volume = "30",
number = "4",
pages = "634--635",
journal = "EMBO Journal",
issn = "0261-4189",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - AMPK and autophagy get connected

A1 - Hardie,D. Grahame

AU - Hardie,D. Grahame

PY - 2011/2/16

Y1 - 2011/2/16

N2 - <p>The energy sensor AMP-activated protein kinase (AMPK), which is activated by ATP depletion or glucose starvation, was previously thought to activate autophagy entirely through its ability to inactivate mTOR complex-1. Two recent papers now provide evidence that it also mediates this by direct phosphorylation of the protein kinase that initiate autophagy, ULK1. Surprisingly, however, the two groups identified different sites on ULK1.</p>

AB - <p>The energy sensor AMP-activated protein kinase (AMPK), which is activated by ATP depletion or glucose starvation, was previously thought to activate autophagy entirely through its ability to inactivate mTOR complex-1. Two recent papers now provide evidence that it also mediates this by direct phosphorylation of the protein kinase that initiate autophagy, ULK1. Surprisingly, however, the two groups identified different sites on ULK1.</p>

KW - CELLULAR-ENERGY

KW - GROWTH

U2 - 10.1038/emboj.2011.12

DO - 10.1038/emboj.2011.12

M1 - Editorial

JO - EMBO Journal

JF - EMBO Journal

SN - 0261-4189

IS - 4

VL - 30

SP - 634

EP - 635

ER -

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