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Anaerobic adaptation in Pseudomonas aeruginosa

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Anaerobic adaptation in Pseudomonas aeruginosa : definition of the Anr and Dnr regulons. / Trunk, Katharina; Benkert, Beatrice; Quaeck, Nicole; Muench, Richard; Scheer, Maurice; Garbe, Julia; Jaensch, Lothar; Trost, Matthias; Wehland, Juergen; Buer, Jan; Jahn, Martina; Schobert, Max; Jahn, Dieter.

In: Environmental Microbiology, Vol. 12, No. 6, 06.2010, p. 1719-1733.

Research output: Contribution to journalArticle

Harvard

Trunk, K, Benkert, B, Quaeck, N, Muench, R, Scheer, M, Garbe, J, Jaensch, L, Trost, M, Wehland, J, Buer, J, Jahn, M, Schobert, M & Jahn, D 2010, 'Anaerobic adaptation in Pseudomonas aeruginosa: definition of the Anr and Dnr regulons' Environmental Microbiology, vol 12, no. 6, pp. 1719-1733.

APA

Trunk, K., Benkert, B., Quaeck, N., Muench, R., Scheer, M., Garbe, J., Jaensch, L., Trost, M., Wehland, J., Buer, J., Jahn, M., Schobert, M., & Jahn, D. (2010). Anaerobic adaptation in Pseudomonas aeruginosa: definition of the Anr and Dnr regulons. Environmental Microbiology, 12(6), 1719-1733doi: 10.1111/j.1462-2920.2010.02252.x

Vancouver

Trunk K, Benkert B, Quaeck N, Muench R, Scheer M, Garbe J et al. Anaerobic adaptation in Pseudomonas aeruginosa: definition of the Anr and Dnr regulons. Environmental Microbiology. 2010 Jun;12(6):1719-1733.

Author

Trunk, Katharina; Benkert, Beatrice; Quaeck, Nicole; Muench, Richard; Scheer, Maurice; Garbe, Julia; Jaensch, Lothar; Trost, Matthias; Wehland, Juergen; Buer, Jan; Jahn, Martina; Schobert, Max; Jahn, Dieter / Anaerobic adaptation in Pseudomonas aeruginosa : definition of the Anr and Dnr regulons.

In: Environmental Microbiology, Vol. 12, No. 6, 06.2010, p. 1719-1733.

Research output: Contribution to journalArticle

Bibtex - Download

@article{ad4c783dcbc3409ab254d4cc3639d966,
title = "Anaerobic adaptation in Pseudomonas aeruginosa",
author = "Katharina Trunk and Beatrice Benkert and Nicole Quaeck and Richard Muench and Maurice Scheer and Julia Garbe and Lothar Jaensch and Matthias Trost and Juergen Wehland and Jan Buer and Martina Jahn and Max Schobert and Dieter Jahn",
year = "2010",
volume = "12",
number = "6",
pages = "1719--1733",
journal = "Environmental Microbiology",
issn = "1462-2912",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Anaerobic adaptation in Pseudomonas aeruginosa

T2 - definition of the Anr and Dnr regulons

A1 - Trunk,Katharina

A1 - Benkert,Beatrice

A1 - Quaeck,Nicole

A1 - Muench,Richard

A1 - Scheer,Maurice

A1 - Garbe,Julia

A1 - Jaensch,Lothar

A1 - Trost,Matthias

A1 - Wehland,Juergen

A1 - Buer,Jan

A1 - Jahn,Martina

A1 - Schobert,Max

A1 - Jahn,Dieter

AU - Trunk,Katharina

AU - Benkert,Beatrice

AU - Quaeck,Nicole

AU - Muench,Richard

AU - Scheer,Maurice

AU - Garbe,Julia

AU - Jaensch,Lothar

AU - Trost,Matthias

AU - Wehland,Juergen

AU - Buer,Jan

AU - Jahn,Martina

AU - Schobert,Max

AU - Jahn,Dieter

PY - 2010/6

Y1 - 2010/6

N2 - <p>The anaerobic metabolism of the opportunistic pathogen Pseudomonas aeruginosa is important for growth and biofilm formation during persistent infections. The two Fnr-type transcription factors Anr and Dnr regulate different parts of the underlying network in response to oxygen tension and NO. Little is known about all members of the Anr and Dnr regulons and the mediated immediate response to oxygen depletion. Comprehensive transcriptome and bioinformatics analyses in combination with a limited proteome analyses were used for the investigation of the P. aeruginosa response to an immediate oxygen depletion and for definition of the corresponding Anr and Dnr regulons. We observed at first the activation of fermentative pathways for immediate energy generation followed by induction of alternative respiratory chains. A solid position weight matrix model was deduced from the experimentally identified Anr boxes and used for identification of 170 putative Anr boxes in potential P. aeruginosa promoter regions. The combination with the experimental data unambiguously identified 130 new members for the Anr and Dnr regulons. The basis for the understanding of two regulons of P. aeruginosa central to biofilm formation and infection is now defined.</p>

AB - <p>The anaerobic metabolism of the opportunistic pathogen Pseudomonas aeruginosa is important for growth and biofilm formation during persistent infections. The two Fnr-type transcription factors Anr and Dnr regulate different parts of the underlying network in response to oxygen tension and NO. Little is known about all members of the Anr and Dnr regulons and the mediated immediate response to oxygen depletion. Comprehensive transcriptome and bioinformatics analyses in combination with a limited proteome analyses were used for the investigation of the P. aeruginosa response to an immediate oxygen depletion and for definition of the corresponding Anr and Dnr regulons. We observed at first the activation of fermentative pathways for immediate energy generation followed by induction of alternative respiratory chains. A solid position weight matrix model was deduced from the experimentally identified Anr boxes and used for identification of 170 putative Anr boxes in potential P. aeruginosa promoter regions. The combination with the experimental data unambiguously identified 130 new members for the Anr and Dnr regulons. The basis for the understanding of two regulons of P. aeruginosa central to biofilm formation and infection is now defined.</p>

U2 - 10.1111/j.1462-2920.2010.02252.x

DO - 10.1111/j.1462-2920.2010.02252.x

M1 - Article

JO - Environmental Microbiology

JF - Environmental Microbiology

SN - 1462-2912

IS - 6

VL - 12

SP - 1719

EP - 1733

ER -

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