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Biomaterials in regenerative medicine

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Biomaterials in regenerative medicine : engineering to recapitulate the natural. / Keatch, Robert P.; Schor, Ana M.; Vorstius, Jan B.; Schor, Seth L.

In: Current Opinion in Biotechnology, Vol. 23, No. 4, 08.2012, p. 579-582.

Research output: Contribution to journalArticle

Harvard

Keatch, RP, Schor, AM, Vorstius, JB & Schor, SL 2012, 'Biomaterials in regenerative medicine: engineering to recapitulate the natural' Current Opinion in Biotechnology, vol 23, no. 4, pp. 579-582., 10.1016/j.copbio.2012.01.017

APA

Keatch, R. P., Schor, A. M., Vorstius, J. B., & Schor, S. L. (2012). Biomaterials in regenerative medicine: engineering to recapitulate the natural. Current Opinion in Biotechnology, 23(4), 579-582. 10.1016/j.copbio.2012.01.017

Vancouver

Keatch RP, Schor AM, Vorstius JB, Schor SL. Biomaterials in regenerative medicine: engineering to recapitulate the natural. Current Opinion in Biotechnology. 2012 Aug;23(4):579-582. Available from: 10.1016/j.copbio.2012.01.017

Author

Keatch, Robert P.; Schor, Ana M.; Vorstius, Jan B.; Schor, Seth L. / Biomaterials in regenerative medicine : engineering to recapitulate the natural.

In: Current Opinion in Biotechnology, Vol. 23, No. 4, 08.2012, p. 579-582.

Research output: Contribution to journalArticle

Bibtex - Download

@article{85230efd011a4a0f8b5b84576ed5e31f,
title = "Biomaterials in regenerative medicine: engineering to recapitulate the natural",
author = "Keatch, {Robert P.} and Schor, {Ana M.} and Vorstius, {Jan B.} and Schor, {Seth L.}",
year = "2012",
doi = "10.1016/j.copbio.2012.01.017",
volume = "23",
number = "4",
pages = "579--582",
journal = "Current Opinion in Biotechnology",
issn = "0958-1669",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Biomaterials in regenerative medicine

T2 - engineering to recapitulate the natural

A1 - Keatch,Robert P.

A1 - Schor,Ana M.

A1 - Vorstius,Jan B.

A1 - Schor,Seth L.

AU - Keatch,Robert P.

AU - Schor,Ana M.

AU - Vorstius,Jan B.

AU - Schor,Seth L.

PY - 2012/8

Y1 - 2012/8

N2 - <p>The functional significance of the extracellular matrix (ECM) has generally been defined in terms of the provision of a structural support for cell adhesion and the establishment of tissue physical integrity. Recent evidence has, however, led to a paradigm shift according to which the ECM is increasingly recognised to exert a profound influence on cell behaviour, including gene expression, migration and the maintenance of functional homeostasis. The objective of this focussed review is to highlight selected observations underpinning this conclusion. Finally, we discuss the implications of these findings for regenerative medicine in the specific context of developing the 'next generation' of advanced wound care devices for the clinical management of recalcitrant chronic wounds.</p>

AB - <p>The functional significance of the extracellular matrix (ECM) has generally been defined in terms of the provision of a structural support for cell adhesion and the establishment of tissue physical integrity. Recent evidence has, however, led to a paradigm shift according to which the ECM is increasingly recognised to exert a profound influence on cell behaviour, including gene expression, migration and the maintenance of functional homeostasis. The objective of this focussed review is to highlight selected observations underpinning this conclusion. Finally, we discuss the implications of these findings for regenerative medicine in the specific context of developing the 'next generation' of advanced wound care devices for the clinical management of recalcitrant chronic wounds.</p>

UR - http://www.scopus.com/inward/record.url?scp=84857976045&partnerID=8YFLogxK

U2 - 10.1016/j.copbio.2012.01.017

DO - 10.1016/j.copbio.2012.01.017

M1 - Article

JO - Current Opinion in Biotechnology

JF - Current Opinion in Biotechnology

SN - 0958-1669

IS - 4

VL - 23

SP - 579

EP - 582

ER -

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